| GenBank top hits | e value | %identity | Alignment |
|---|
| KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma] | 5.3e-219 | 57.61 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYE+WK+NLRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ + HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSN TR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS IPNYNPRDIIRNVRRML GE MLPM PWYRGF GTIEK ATK GGTSYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
+ FLDSVTR+++KNDKDKEK AK PFIEQADHHSDDK VSIDVHLTEENMILA+QEGLK+KFKLT TVSTSNMHLFDAN
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
ELQ KGFTPF KKTKSVEPEVAGASNET +K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
Query: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
DK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDA A+ VR QQR I NN++KPK+SRNAPKAPR+SKKT+N ET ESM
Subjt: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
Query: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
D T SSSTTTEVA+N VVKPKGKAAPRKAPAKK QGKA V +D ++DDEVLEL+DRLAAYK++SSP+ SEVSAMETEVP AKKKEPSKRAAAKKK
Subjt: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
Query: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
TTAKSAQ S DDSD+ DF++KEIAP P AKK GGGRKAAANAKTTK + K
Subjt: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
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| XP_022152631.1 DNA topoisomerase 2 isoform X1 [Momordica charantia] | 2.8e-220 | 57.67 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYESWKE+LRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ ++ HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSNVTR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS +PNYNPRDII NV+R+L+GETM+PM PWY+GF G IEK ATK GG SYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
++FLDSVTR+A+KN DKEK AK PFIEQADHHSDDK VSIDVHLTEENMILALQEGLK+KFKLT TVSTSNMHLFD+N
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET--------MKQRRVRK--------
ELQAKGFTPF KKTKSVEPEVAGASNET K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET--------MKQRRVRK--------
Query: -------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRN-APKAPRDSKKTTNLETNLESM
+ D+LKGEVEDLRKATPKSLWLKDLD+LEKELDEMDRNDA AE VR QQR+ ANN+VKPK+SRN APKAPR+SKKT N ET ESM
Subjt: -------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRN-APKAPRDSKKTTNLETNLESM
Query: DTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKKT
DT SSSTT EVASNAVVKPKGKAAPRKAPAKK GK VVN + ++DDEVLEL+DRLAAYKIDSSPDRSEVSAMETEVP AKKKEPSKRA AKKKT
Subjt: DTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKKT
Query: TAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKP
TAKSAQ S++DDSD++DF++KE+AP P AKKGGG + AANAKTTKP
Subjt: TAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKP
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| XP_022935015.1 DNA topoisomerase 2 isoform X1 [Cucurbita moschata] | 1.2e-218 | 57.38 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYE+WK+NLRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ + HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSN TR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS IPNYNPRDIIRNVRRML GE MLPM PWYRGF GTIEK ATK GGTSYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
+ FLDSVTR+++KNDKDKEK AK PFIEQADHHSDDK VSIDVHLTEENMILA+QEGLK+KFKLT TVSTSNMHLFDAN
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
ELQ KGFTPF KKTKSVEPEVAGASNET +K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
Query: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
DK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDA A+ VR QQR I NN++KPK+SRNAPKAPR+SKKT+N ET ESM
Subjt: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
Query: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
D T SSSTTTEVA+N VVKPKGKAAPRKAPAKK QGK V +D ++DDEVLEL+DRLAAYK++SSP+ SEVSAMETEVP AKKKEPSKRAAAKKK
Subjt: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
Query: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
TTAKSAQ S DDSD+ DF++KEIAP P AKK GGGRKAAANAKTTK ++++
Subjt: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
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| XP_023527820.1 DNA topoisomerase 2 isoform X1 [Cucurbita pepo subsp. pepo] | 8.2e-220 | 57.73 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYE+WK+NLRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ + HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSN TR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS IPNYNPRDIIRNVRRML GE MLPM PWYRGF GTIEK ATK GGTSYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
+ FLDSVTR+++KNDKDKEK AK PFIEQADHHSDDK VSIDVHLTEENMILA+QEGLK+KFKLT TVSTSNMHLFDAN
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
ELQ KGFTPF KKTKSVEPEVAGASNET +K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
Query: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
DK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDA A+ VR QQR I NN+VKPK+SRNAPKAPR+SKKT+N ET ESM
Subjt: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
Query: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
D T SSSTTTEVA+N VVKPKGKAAPRKAPAKK QGKA V +D ++DDEVLEL+DRLAAYK++SSP+ SEVSAMETEVP AKKKEPSKRAAAKKK
Subjt: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
Query: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
TTAKSAQ S DDSDN DF++KEIAP P AKK GGGRKAAANAKTTK ++++
Subjt: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
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| XP_023527823.1 DNA topoisomerase 2 isoform X3 [Cucurbita pepo subsp. pepo] | 4.1e-219 | 57.61 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYE+WK+NLRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ + HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSN TR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS IPNYNPRDIIRNVRRML GE MLPM PWYRGF GTIEK ATK GGTSYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
+ FLDSVTR+++KNDKDKEK AK PFIEQADHHSDDK VSIDVHLTEENMILA+QEGLK+KFKLT TVSTSNMHLFDAN
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
ELQ KGFTPF KKTKSVEPEVAGASNET +K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
Query: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
DK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDA A+ VR QQR I NN+VKPK+SRNAPKAPR+SKKT+N ET ESM
Subjt: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
Query: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
D T SSSTTTEVA+N VVKPKGKAAPRKAPAKK GKA V +D ++DDEVLEL+DRLAAYK++SSP+ SEVSAMETEVP AKKKEPSKRAAAKKK
Subjt: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
Query: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
TTAKSAQ S DDSDN DF++KEIAP P AKK GGGRKAAANAKTTK ++++
Subjt: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
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| TrEMBL top hits | e value | %identity | Alignment |
|---|
| A0A6J1DGT3 DNA topoisomerase 2 | 3.7e-218 | 57.43 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYESWKE+LRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ ++ HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSNVTR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS +PNYNPRDII NV+R+L+GETM+PM PWY+GF G IEK ATK GG SYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
++FLDSVTR+A+KN DKEK AK PFIEQADHHSDDK VSIDVHLTEENMILALQEGLK+KFKLT TVSTSNMHLFD+N
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET--------MKQRRVRK--------
ELQAKGFTPF KKTKSVEPEVAGASNET K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET--------MKQRRVRK--------
Query: -------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRN-APKAPRDSKKTTNLETNLESM
+ D+LKGEVEDLRKATPKSLWLKDLD+LEKELDEMDRNDA AE VR QQR+ ANN+VKPK+SRN APKAPR+SKKT N ET ESM
Subjt: -------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRN-APKAPRDSKKTTNLETNLESM
Query: DTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKKT
DT SSSTT EVASNAVVKPKGKAAPRKAPAKK GK VVN + ++DDEVLEL+DRLAAYKIDSSPDRSE AMETEVP AKKKEPSKRA AKKKT
Subjt: DTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKKT
Query: TAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKP
TAKSAQ S++DDSD++DF++KE+AP P AKKGGG + AANAKTTKP
Subjt: TAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKP
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| A0A6J1DIB5 DNA topoisomerase 2 | 1.4e-220 | 57.67 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYESWKE+LRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ ++ HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSNVTR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS +PNYNPRDII NV+R+L+GETM+PM PWY+GF G IEK ATK GG SYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
++FLDSVTR+A+KN DKEK AK PFIEQADHHSDDK VSIDVHLTEENMILALQEGLK+KFKLT TVSTSNMHLFD+N
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET--------MKQRRVRK--------
ELQAKGFTPF KKTKSVEPEVAGASNET K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET--------MKQRRVRK--------
Query: -------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRN-APKAPRDSKKTTNLETNLESM
+ D+LKGEVEDLRKATPKSLWLKDLD+LEKELDEMDRNDA AE VR QQR+ ANN+VKPK+SRN APKAPR+SKKT N ET ESM
Subjt: -------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRN-APKAPRDSKKTTNLETNLESM
Query: DTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKKT
DT SSSTT EVASNAVVKPKGKAAPRKAPAKK GK VVN + ++DDEVLEL+DRLAAYKIDSSPDRSEVSAMETEVP AKKKEPSKRA AKKKT
Subjt: DTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKKT
Query: TAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKP
TAKSAQ S++DDSD++DF++KE+AP P AKKGGG + AANAKTTKP
Subjt: TAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKP
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| A0A6J1F3D6 DNA topoisomerase 2 | 2.9e-218 | 57.26 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYE+WK+NLRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ + HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSN TR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS IPNYNPRDIIRNVRRML GE MLPM PWYRGF GTIEK ATK GGTSYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
+ FLDSVTR+++KNDKDKEK AK PFIEQADHHSDDK VSIDVHLTEENMILA+QEGLK+KFKLT TVSTSNMHLFDAN
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
ELQ KGFTPF KKTKSVEPEVAGASNET +K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
Query: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
DK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDA A+ VR QQR I NN++KPK+SRNAPKAPR+SKKT+N ET ESM
Subjt: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
Query: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
D T SSSTTTEVA+N VVKPKGKAAPRKAPAKK GK V +D ++DDEVLEL+DRLAAYK++SSP+ SEVSAMETEVP AKKKEPSKRAAAKKK
Subjt: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
Query: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
TTAKSAQ S DDSD+ DF++KEIAP P AKK GGGRKAAANAKTTK ++++
Subjt: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
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| A0A6J1F9E0 DNA topoisomerase 2 | 5.8e-219 | 57.38 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYE+WK+NLRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ + HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSN TR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS IPNYNPRDIIRNVRRML GE MLPM PWYRGF GTIEK ATK GGTSYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
+ FLDSVTR+++KNDKDKEK AK PFIEQADHHSDDK VSIDVHLTEENMILA+QEGLK+KFKLT TVSTSNMHLFDAN
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
ELQ KGFTPF KKTKSVEPEVAGASNET +K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
Query: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
DK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDA A+ VR QQR I NN++KPK+SRNAPKAPR+SKKT+N ET ESM
Subjt: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
Query: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
D T SSSTTTEVA+N VVKPKGKAAPRKAPAKK QGK V +D ++DDEVLEL+DRLAAYK++SSP+ SEVSAMETEVP AKKKEPSKRAAAKKK
Subjt: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
Query: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
TTAKSAQ S DDSD+ DF++KEIAP P AKK GGGRKAAANAKTTK ++++
Subjt: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
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| A0A6J1IWX9 DNA topoisomerase 2 | 4.9e-218 | 57.26 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLLRVPSFLVEFITP+ + ATHRNGTVLSFYTMPEYE+WK+NLRGNASGWSIKY GLGTSTSKEGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
F+QL KHKK+ + HDGEAIELAFSKKKIEER N LIL + +Q
Subjt: FDQLEKHKKNLFGRC-HDGEAIELAFSKKKIEER--------------------------NLRLILKLICFIQ---------------------------
Query: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
GGKDHASSRYIYTKLSN TR
Subjt: --------------------------------------------------------GGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNGSEGIGTGWSS IPNYNPRDIIRNVRRML+GE MLPM PWYRGF GTIEK ATK GGTSYTVSGIIE VSDT LRI ELPV +WTN Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
+ FLDSVTR+++KNDKDKEK AK PFIEQADHHSDDK VSI+VHLTEENMILA+QEGLK+KFKLT TVSTSNMHLFDAN
Subjt: RKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN---------------------
Query: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
ELQ KGFTPF KKTKSVEPEVAGASNET +K RV
Subjt: ------------------------------------------------ELQAKGFTPFSKKTKSVEPEVAGASNET---------MKQRRVRK-------
Query: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
DK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDA A+ VR QQR I NN++KPK+SRNAPKAPR+SKKT+N ET ESM
Subjt: --------------GNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESM
Query: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
D SSSTTTEVA+N VVKPKGKAAPRKAPAKK QGKA V +D + DDEVLEL+DRLAAYK++SSP+ SEVSAMETEVP AKKKEPSKRAAAKKK
Subjt: D-TVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEVP-----AKKKEPSKRAAAKKK
Query: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
TTAKSAQ S DDSD+ DF++KEIAP P AKK GGGRKAAANAKTTK ++++
Subjt: TTAKSAQTSNHDDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRK
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| SwissProt top hits | e value | %identity | Alignment |
|---|
| O24308 DNA topoisomerase 2 | 3.6e-109 | 36.13 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLL+VPSFLVEF TP+ R A+H N T+ SFY+MPEYE+WKE L +A+ W IKY GLGTST +EGREY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLIL------------------KLICFI----------
F L +H+K+ ++ DG AIELAFSKKK E R N LIL K+ FI
Subjt: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLIL------------------KLICFI----------
Query: ------------------------------------QGGKDHASSRYIYTKLSNVTR-------------------------YMPIIPMVLVNGSEGIGT
GGKDHAS+RYIYT+LS VTR YMPIIP+VLVNGSEGIGT
Subjt: ------------------------------------QGGKDHASSRYIYTKLSNVTR-------------------------YMPIIPMVLVNGSEGIGT
Query: GWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKGGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKYRKFLDSVTRIASKNDKDKEK
GWSS IPNYNPR+II NVRR+L GE ++PM PWY+GF GTIEK A +GG Y V+G + + + RI ELP+ +WT Y++FL+S+T D
Subjt: GWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKGGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKYRKFLDSVTRIASKNDKDKEK
Query: TAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN-----------------------------------------
K P IE + DD IV I++ + E + LQEGL +KFKLT T+STSNMHLFDA
Subjt: TAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN-----------------------------------------
Query: ---------------------------ELQAKGFTPFSKKTKSVEPEVAGASNE------------------------------------TMKQRRVRKG
EL+ KGFTP +K KS +P+VAGA+++ T+ V+K
Subjt: ---------------------------ELQAKGFTPFSKKTKSVEPEVAGASNE------------------------------------TMKQRRVRKG
Query: NEDKLKGEVE-DLRKATP-KSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESMDTVSSSTTTEVAS
++K + E E ++ TP SLWLKDLD EK+LDE+D A + R Q N K ++ P+ +++KK ++E ++ +
Subjt: NEDKLKGEVE-DLRKATP-KSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANNEVKPKLSRNAPKAPRDSKKTTNLETNLESMDTVSSSTTTEVAS
Query: NAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETE----VPAKKKEPSKRAAAKKKTTA---KSAQTSNHD
V KPKG+AAP+K N+ E +D++ L++RLAAY I+SS ++S+ AME+E A KK+ +KR AKKK++ +S + +
Subjt: NAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETE----VPAKKKEPSKRAAAKKKTTA---KSAQTSNHD
Query: DSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAK
D D++D +E+ A KK GG + AA NAK
Subjt: DSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAK
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| P08096 DNA topoisomerase 2 | 1.9e-57 | 33.26 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++N++ S +PSLL++P FL++FITP+ + R V +FYT+PEYE WKE N GW IKY GLGTS + + Y
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFG-RCHDGEAIELAFSKKKIEER-------------------------------------NLRLILKLI-------------CF-----
F L++H K + D E IE+AF+KKK + R N+R I ++ CF
Subjt: FDQLEKHKKNLFG-RCHDGEAIELAFSKKKIEER-------------------------------------NLRLILKLI-------------CF-----
Query: ------------------------------------------------------IQGGKDHASSRYIYTKLSNVTR------------------------
+GGK+ ++SRY+ T LS + R
Subjt: ------------------------------------------------------IQGGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKGGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKYR
Y+PI+PMVLVNG+EGIGTGWS+ IPNYNP+DI N+R ML GE + M PWYRGF G+I K+A Y +SGII + + + I ELP+ WT +
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKGGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKYR
Query: KFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN
++L++ EK K FI + H + V +V LTE M AL E L+ KFKL++T +TSNM FDA+
Subjt: KFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDAN
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| P30182 DNA topoisomerase 2 | 9.5e-102 | 34.26 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++NFIHSFWPSLL+VPSFLVEFITP+ + VLSFY+MPEYE WKE+L+GNA+GW IKY GLGTST++EG+EY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLIL---------------------KLICFI-------
F L HKK+ ++ DGEAIELAFSKKKIE R N LIL + I F+
Subjt: FDQLEKHKKN-LFGRCHDGEAIELAFSKKKIEER--------------------------NLRLIL---------------------KLICFI-------
Query: -------------------------------------------------------QGGKDHASSRYIYTKLSNVTR------------------------
GGKD AS+RYI+TKLS VTR
Subjt: -------------------------------------------------------QGGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
YMPIIP VLVNG+EGIGTGWS+ IPNYNPR+I+ NVRR+L GE+M+PM PWYRGF GTIEK A+K GG +YT++G+ E V +T +RI ELP+ +W + Y
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATK-GGTSYTVSGIIEVVSDTMLRIIELPVCQWTNKY
Query: RKFLDSVTRIASKNDKDKEKTAKG-PFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFD----------------------
+ FL S+ KT G PF + ++D+K V D+ L+EENM+ A QEG +KFKLT T++TSNMHLFD
Subjt: RKFLDSVTRIASKNDKDKEKTAKG-PFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFD----------------------
Query: -----------------------------------------------ANELQAKGFTPFSKKTKSVEPEVAGASNE------------------------
+L+ KGFTPF +K +SVE +AGA ++
Subjt: -----------------------------------------------ANELQAKGFTPFSKKTKSVEPEVAGASNE------------------------
Query: ------------TMKQRRVRKGNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENV--RIQQRVIANNEVKPKLSRNAPKAPRDSKKTT
T+++ + DK+ V D++K TPKSLWL DL+SL+KEL+++D DA + Q+++ A + K+ R APK P KKTT
Subjt: ------------TMKQRRVRKGNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENV--RIQQRVIANNEVKPKLSRNAPKAPRDSKKTT
Query: NLETNLESMDTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEED-DEVLELRDRLAAYKIDSSPDRSEVSAMETEVPAKKKEPSKRAA
+ E+ + S+ T+ VVKPK + +K ++ +A +D++ + EV++ + R A K +P ++ + + ++
Subjt: NLETNLESMDTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEED-DEVLELRDRLAAYKIDSSPDRSEVSAMETEVPAKKKEPSKRAA
Query: AKKKTTAKSAQTSNH-DDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRKGG
+ ++K+A+TS D++D V E+AP KK GGRK AA P RK G
Subjt: AKKKTTAKSAQTSNH-DDSDNEDFKVKEIAPSAPTAKKGGGGRKAAANAKTTKPRRRRKGG
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| Q55BP5 Probable DNA topoisomerase 2 | 2.1e-53 | 26.66 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
DHDGSHIKGL++N +H FWP+LLR+P FLVEFITP+ ++ + N +SFYTMPE+ W+E N GW +KY GLGTST EG+EY
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRLATHRNGTVLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEGREY
Query: FDQLEKHKKNLFGRCHDGEAIELAFSKKKIEER---------------------------NLRLILKLI------------------------CF-----
F LE+HK + + IELAFSK + ++R N L+L I CF
Subjt: FDQLEKHKKNLFGRCHDGEAIELAFSKKKIEER---------------------------NLRLILKLI------------------------CF-----
Query: ------------------------------------------------------IQGGKDHASSRYIYTKLSNVTR------------------------
I GGKD +S+RYI+T+L+++ R
Subjt: ------------------------------------------------------IQGGKDHASSRYIYTKLSNVTR------------------------
Query: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKG----GTSYTVSGIIEVVSDTMLRIIELPVCQWT
Y+P+IPM+LVNG GIGTGWSS+IPNYNPRD+I+N+R ++G+ + P+ PWYRGFLG+IE A +G G Y GI + +SD I ELP+ WT
Subjt: -YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKG----GTSYTVSGIIEVVSDTMLRIIELPVCQWT
Query: NKYRKFLDSV----TRIASKNDKDK-------------------------------EKTAKG--------------PFIEQADHHSDDKIVSIDVHLTEE
YR+ LD + TR K +K+K E T K I+ D + +K+ + + E
Subjt: NKYRKFLDSV----TRIASKNDKDK-------------------------------EKTAKG--------------PFIEQADHHSDDKIVSIDVHLTEE
Query: NMILALQEGLKEKFKLT---------------------------------------------KTVSTSNMHLFD-ANELQAKGF-------------TPF
NM++ +EG ++F T K + SN+ D N+L+ F
Subjt: NMILALQEGLKEKFKLT---------------------------------------------KTVSTSNMHLFD-ANELQAKGF-------------TPF
Query: SKKTKSVEPEVAGASNETMKQ--------------------------RRVRKGNEDKLKGEVE-DLRKATP-KSLWLKDLDSLEKELDEMDRNDAHAENV
KK + + E A S++ K RV+K E++ + E D+ +TP + ++ +DLD+LEK LD+ D D +N
Subjt: SKKTKSVEPEVAGASNETMKQ--------------------------RRVRKGNEDKLKGEVE-DLRKATP-KSLWLKDLDSLEKELDEMDRNDAHAENV
Query: RIQQRVIANNEVKPKLSRNAPKAPRDSKKT-------------TNLETNL------ESMDTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVN
+ + P+ + + K +D+K+ T ++N+ +S DT S+ST+T +SN A K P ++ K+ +V+
Subjt: RIQQRVIANNEVKPKLSRNAPKAPRDSKKT-------------TNLETNL------ESMDTVSSSTTTEVASNAVVKPKGKAAPRKAPAKKLQGKAIVVN
Query: VDSE---EDDEVLELRDRLAAYK----IDSSPDRSEVSAMETEVPAKKKEPSKRAAA--KKKTT--AKSAQTSNH---DDSDNEDFKVK
+DS+ +DD V+ + + K I+ S + + S E++ + + P KR+ A KK TT K A TS DD ++D +K
Subjt: VDSE---EDDEVLELRDRLAAYK----IDSSPDRSEVSAMETEVPAKKKEPSKRAAA--KKKTT--AKSAQTSNH---DDSDNEDFKVK
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| Q9Y8G8 DNA topoisomerase 2 | 1.9e-54 | 28.22 | Show/hide |
Query: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRL--ATHRNGT-VLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEG
DHDGSHIKGL++NF+ + +PSLL++P FL+EFITP+ ++ +N T SF+TMPEYE+WKE G+ GW KY GLGTST+++
Subjt: DHDGSHIKGLVLNFIHSFWPSLLRVPSFLVEFITPLSRL--ATHRNGT-VLSFYTMPEYESWKENLRGNASGWSIKYTIRSCINSLSDCVGLGTSTSKEG
Query: REYFDQLEKHKKNLFGRCHDGEA--IELAFSKKKIEER-------------------------------------NLRLILKLI-------------CF-
+ YF L++H K F D E IELAFSKKK +ER N+R I ++ CF
Subjt: REYFDQLEKHKKNLFGRCHDGEA--IELAFSKKKIEER-------------------------------------NLRLILKLI-------------CF-
Query: ----------------------------------------------------------IQGGKDHASSRYIYTKLSNVTR--------------------
+QGG D AS+RYIYT+L R
Subjt: ----------------------------------------------------------IQGGKDHASSRYIYTKLSNVTR--------------------
Query: -----YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKGGTSYTVSGIIEVVSDTMLRIIELPVCQWT
Y+P++PM+L+NG++GIGTGWSSS PNYNP DI+ N++RM++GE + PM PW+RGF G + + G + SGII+ D + I ELP+ WT
Subjt: -----YMPIIPMVLVNGSEGIGTGWSSSIPNYNPRDIIRNVRRMLEGETMLPMHPWYRGFLGTIEKIATKGGTSYTVSGIIEVVSDTMLRIIELPVCQWT
Query: NKYRKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDANELQAKGFTPFSKKTKSVE
++ L+ + + EKT FI+ ++ V + + E++M A+ EGL+EKFKL+KT++T+N+ FD + K SVE
Subjt: NKYRKFLDSVTRIASKNDKDKEKTAKGPFIEQADHHSDDKIVSIDVHLTEENMILALQEGLKEKFKLTKTVSTSNMHLFDANELQAKGFTPFSKKTKSVE
Query: PEVAGASNETMKQRRVRKGNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANN-------EVKPKLSRNAPKAPRDSKK
+ +K RK + L ++KELD++ + + + VI+ E+K K + PK +++ K
Subjt: PEVAGASNETMKQRRVRKGNEDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAHAENVRIQQRVIANN-------EVKPKLSRNAPKAPRDSKK
Query: TTNLETNLESMDTVSSSTTTEVASN-----------AVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEV
E +E + S S TEV SN ++ + + + R+ K+L+ ++ S+ED +L D + ++ + E
Subjt: TTNLETNLESMDTVSSSTTTEVASN-----------AVVKPKGKAAPRKAPAKKLQGKAIVVNVDSEEDDEVLELRDRLAAYKIDSSPDRSEVSAMETEV
Query: PAKKKEPSKRAAAKKKTT-------AKSAQTSNHDDSDNEDF---KVKEIAPSAPTAKKGGG
K +R ++K TT A+ + + DD D+EDF K K+ A + T KGGG
Subjt: PAKKKEPSKRAAAKKKTT-------AKSAQTSNHDDSDNEDF---KVKEIAPSAPTAKKGGG
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