CuGenDBv2

Gene ID	Lag0018248
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	Delta-1-pyrroline-5-carboxylate synthase
Genome location	chr5:20363788..20370730
RNA-Seq Expression	Lag0018248
Synteny	Lag0018248
Gene Ontology terms	GO:0006561 - proline biosynthetic process (biological process) GO:0016020 - membrane (cellular component) GO:0000166 - nucleotide binding (molecular function) GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity (molecular function) GO:0016301 - kinase activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

AKP99746.1 delta-1-pyrroline-5-carboxylate synthase [Cucumis sativus]

4.2e-07

66.67

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR IL+DV       ENMI+AEN  DIKA ++AGYEK LIS LALK GKV
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

XP_011651884.1 delta-1-pyrroline-5-carboxylate synthase isoform X3 [Cucumis sativus]

4.2e-07

66.67

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR IL+DV       ENMI+AEN  DIKA ++AGYEK LIS LALK GKV
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

XP_022982660.1 delta-1-pyrroline-5-carboxylate synthase-like isoform X1 [Cucurbita maxima]

1.1e-07

68.42

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR ILLDV       ENMIIAEN  DIKA ++AGYEKSLIS LALK G++
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

XP_022982661.1 delta-1-pyrroline-5-carboxylate synthase-like isoform X2 [Cucurbita maxima]

1.1e-07

68.42

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR ILLDV       ENMIIAEN  DIKA ++AGYEKSLIS LALK G++
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

XP_022982662.1 delta-1-pyrroline-5-carboxylate synthase-like isoform X3 [Cucurbita maxima]

1.1e-07

68.42

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR ILLDV       ENMIIAEN  DIKA ++AGYEKSLIS LALK G++
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LAF9 Delta-1-pyrroline-5-carboxylate synthase

2.0e-07

66.67

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR IL+DV       ENMI+AEN  DIKA ++AGYEK LIS LALK GKV
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

A0A2D0UVX8 Delta-1-pyrroline-5-carboxylate synthase

2.0e-07

66.67

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR IL+DV       ENMI+AEN  DIKA ++AGYEK LIS LALK GKV
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

A0A6J1IX71 Delta-1-pyrroline-5-carboxylate synthase

5.4e-08

68.42

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR ILLDV       ENMIIAEN  DIKA ++AGYEKSLIS LALK G++
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

A0A6J1IZY8 Delta-1-pyrroline-5-carboxylate synthase

5.4e-08

68.42

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR ILLDV       ENMIIAEN  DIKA ++AGYEKSLIS LALK G++
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

A0A6J1J3D4 Delta-1-pyrroline-5-carboxylate synthase

5.4e-08

68.42

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV
        QALK EDRR ILLDV       ENMIIAEN  DIKA ++AGYEKSLIS LALK G++
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKV

SwissProt top hits

e value

%identity

Alignment

O04015 Delta-1-pyrroline-5-carboxylate synthase

1.1e-05

44.44

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEITMNWVMLRRRKE
        QA+  +DR  ILLDV       E +I  EN  D+ A + AGYEKSLIS LALK GK+  +  +  +L   +E
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEITMNWVMLRRRKE

P54888 Delta-1-pyrroline-5-carboxylate synthase B

1.2e-04

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Query:  QALKFEDRRNIL------LDVVENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI
        QAL  EDR+ IL      L+V E  I AEN +D+ A ++AGYE+SL++ L +K GK+  +
Subjt:  QALKFEDRRNIL------LDVVENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI

Q941T1 Delta-1-pyrroline-5-carboxylate synthase 2

7.8e-04

36.67

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI
        Q L  E+R+ ILLD+       E++I +EN  D+   +D GY+KSL++ + +K GK+  +
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI

Q96480 Delta-1-pyrroline-5-carboxylate synthase

9.2e-05

46.67

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Query:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI
        QAL  ++R  IL D+       E  I+AEN  D+ A + AGYEKSLIS LAL  GK+  +
Subjt:  QALKFEDRRNILLDVV------ENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI

Arabidopsis top hits

e value

%identity

Alignment

AT3G55610.1 delta 1-pyrroline-5-carboxylate synthase 2

8.5e-06

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Query:  QALKFEDRRNIL------LDVVENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI
        QAL  EDR+ IL      L+V E  I AEN +D+ A ++AGYE+SL++ L +K GK+  +
Subjt:  QALKFEDRRNIL------LDVVENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI

AT3G55610.2 delta 1-pyrroline-5-carboxylate synthase 2

8.5e-06

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Query:  QALKFEDRRNIL------LDVVENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI
        QAL  EDR+ IL      L+V E  I AEN +D+ A ++AGYE+SL++ L +K GK+  +
Subjt:  QALKFEDRRNIL------LDVVENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEI

Sequences

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CDS sequence

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ATGGCTTGTGTTTGGCTTTTGATCCTCGCTTATCAGGCTCTCAAATTTGAAGATAGGAGAAACATATTGCTGGATGTAGTTGAAAATATGATTATCGCTGAGAACTATGT
TGATATTAAAGCTACTAAGGATGCTGGTTATGAGAAGTCTTTGATATCTTGTTTGGCTCTAAAGCTTGGAAAGGTGATGGAGATTACTATGAATTGGGTGATGTTGAGGA
GGAGAAAGGAGGGTAAAACTGGAATCGAAAGACAGAATTGTTGTGTCATGGATGGAACCACTGCCTTGAAAGCAAAACTCGACACGACCTCGGTGCTAAATCGTTTAACT
GCCGGTTTCGATGTTATTCCTGTACGCATGCTATTTGGTGGCAATTGGAATAAGAGGAACAATTATGTTGACTATAATGAAATGGTTGATTGGAGCTATAATGCAATATC
AGAGTTAATCGGGTGCTCGAGGCGTGAAAAGATGCAAAGGAATGAAAAGAGTAAAAGTGAAAAAAAGTCAAATCTCGGTCAACAGCAGGCTAGCGTCGAGACGCTAGCTC
TTGAGCGTCTCGACGCTCACATTCCATATCAGATTAGGCGCGTAAAGCTTACAGCGTCGAGACGCTATGATAGGAAGCGTCCCGACGCTACCGTTTTTCCTTATTCAGAA
CGCGCGTATAAGAGGCAGCGTCGCGACGCTGTCTTGACAGCGTCTCGACGCTAA

mRNA sequence

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Protein sequence

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MACVWLLILAYQALKFEDRRNILLDVVENMIIAENYVDIKATKDAGYEKSLISCLALKLGKVMEITMNWVMLRRRKEGKTGIERQNCCVMDGTTALKAKLDTTSVLNRLT
AGFDVIPVRMLFGGNWNKRNNYVDYNEMVDWSYNAISELIGCSRREKMQRNEKSKSEKKSNLGQQQASVETLALERLDAHIPYQIRRVKLTASRRYDRKRPDATVFPYSE
RAYKRQRRDAVLTASRR

Lag0018248 (gene) of Sponge gourd (AG-4) v1 genome