CuGenDBv2

Gene ID	Lag0021772
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	dCTP pyrophosphatase 1
Genome location	chr7:11797644..11798814
RNA-Seq Expression	Lag0021772
Synteny	Lag0021772
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022145107.1 dCTP pyrophosphatase 1-like [Momordica charantia]

7.4e-63

88.44

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MA+ A   EVTL++LKT MAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWK+EEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQ--DDCNENGGKEEEDPTKQ
        RKL LNAKKYPVKLCKGSSRKHTQI CQ  D C+ENGG EEEDPTK+
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQ--DDCNENGGKEEEDPTKQ

XP_022955550.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

4.8e-62

88.36

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        M E  +R EVTL+ELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLP WKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ
        RKL LNAKKYPVKLCKGSSRKHTQIS  + DCNE+ GK  EDP KQ
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ

XP_022979978.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

2.8e-62

88.36

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MAE  +R EVTL+ELKTMMA+FARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLP WKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ
        RKL LNAKKYPVKLCKGSSRKHTQIS  + DCNE+ GK  EDP+KQ
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ

XP_023526028.1 dCTP pyrophosphatase 1-like [Cucurbita pepo subsp. pepo]

4.8e-62

88.36

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MAE  +R EVTL+ELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLP WK+EEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ
        RKL LNAKKYPVKLCKGSSRKHTQIS  + DCNE+ GK  EDP+KQ
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ

XP_038877931.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

1.3e-67

90.97

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MAE  + EEVTL++LKTMMA+FA+ERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKA L
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTK
        RKL LN KKYPVKLCKGSSRKHTQISC+DDCNENGGK EEDPTK
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTK

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BYE4 dCTP pyrophosphatase 1

5.7e-61

83.33

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MAE  +  +VTL++LK MMA+FA+ERDWDQFHSPRNLLLAMV EVGELSEIFQWKGEVPRGLPDWK+EEKQHLGEELSDVLLYLVRLADICGIDLGKA L
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTK
        RK+ LN KKYPV+LCKGSSRKHT+ISC++ CNENGGK E+DPTK
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTK

A0A5D3D2K4 dCTP pyrophosphatase 1

5.7e-61

83.33

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MAE  +  +VTL++LK MMA+FA+ERDWDQFHSPRNLLLAMV EVGELSEIFQWKGEVPRGLPDWK+EEKQHLGEELSDVLLYLVRLADICGIDLGKA L
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTK
        RK+ LN KKYPV+LCKGSSRKHT+ISC++ CNENGGK E+DPTK
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTK

A0A6J1CVJ8 dCTP pyrophosphatase 1

3.6e-63

88.44

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MA+ A   EVTL++LKT MAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWK+EEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQ--DDCNENGGKEEEDPTKQ
        RKL LNAKKYPVKLCKGSSRKHTQI CQ  D C+ENGG EEEDPTK+
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQ--DDCNENGGKEEEDPTKQ

A0A6J1GVE4 dCTP pyrophosphatase 1

2.3e-62

88.36

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        M E  +R EVTL+ELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLP WKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ
        RKL LNAKKYPVKLCKGSSRKHTQIS  + DCNE+ GK  EDP KQ
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ

A0A6J1IXV8 dCTP pyrophosphatase 1

1.4e-62

88.36

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Query:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
        MAE  +R EVTL+ELKTMMA+FARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLP WKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL
Subjt:  MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAAL

Query:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ
        RKL LNAKKYPVKLCKGSSRKHTQIS  + DCNE+ GK  EDP+KQ
Subjt:  RKLGLNAKKYPVKLCKGSSRKHTQISCQD-DCNENGGKEEEDPTKQ

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

6.6e-30

49.64

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Query:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK
        E TLE+++ + AEFA ERDW+QFH PRNLLLA+VGEVGEL+E+FQWK +   G   W   E+  L EELSD+L+YLV LA  C +DL +A L K+  N +
Subjt:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK

Query:  KYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTKQ
        +YPV L +GS+ K+T +      +EN      DP  +
Subjt:  KYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTKQ

Q91VC0 dCTP pyrophosphatase 1

7.8e-31

49.64

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Query:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK
        E TLE+++ + AEFA ERDW+QFH PRNLLLA+VGEVGEL+E+FQWK +   G   W+ +E+  L EELSDVL+YLV LA  C +DL +A + K+  N +
Subjt:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK

Query:  KYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTKQ
        +YPV L +GS+ K+T +  +   +EN      DP  +
Subjt:  KYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTKQ

Q9H773 dCTP pyrophosphatase 1

1.6e-31

55.56

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Query:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK
        E TLE+++ + AEFA ERDW+QFH PRNLLLA+VGEVGEL+E+FQWK +   G   W   E+  L EELSDVL+YLV LA  C +DL  A L K+ +N +
Subjt:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK

Query:  KYPVKLCKGSSRKHTQI
        +YP  L + SSRK+T++
Subjt:  KYPVKLCKGSSRKHTQI

Q9QY93 dCTP pyrophosphatase 1

2.3e-30

49.64

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Query:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK
        E TLE+++ + AEFA ERDW+QFH PRNLLLA+VGEVGEL+E+FQWK +   G   W  +E+  L EELSDVL+YLV LA  C +DL +A + K+  N +
Subjt:  EVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAK

Query:  KYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTKQ
        +YPV L +GS+ K+T +  +   +EN      DP  +
Subjt:  KYPVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTKQ

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

6.9e-43

65.65

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Query:  REEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLN
        +E V+L+ L   M +FA+ RDW+++HSPRNLLLAMVGEVGELSEIFQWKGEV RG PDWK+EEK HLGEELSDVLLYLVRL+D CG+DLGKAALRK+ LN
Subjt:  REEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLN

Query:  AKKYPVKLCKGSSRKHTQISCQDDCNENGGK
        A KYPV        K T   C  D  ++  K
Subjt:  AKKYPVKLCKGSSRKHTQISCQDDCNENGGK

Sequences

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CDS sequence

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ATGGCGGAGGCTGCAAAGAGGGAGGAGGTCACTCTCGAGGAGTTGAAGACGATGATGGCCGAGTTTGCGAGAGAGAGGGACTGGGATCAGTTTCATAGCCCTAGAAATCT
CCTTCTCGCTATGGTGGGTGAAGTGGGCGAGTTGTCTGAGATATTCCAGTGGAAAGGGGAGGTTCCAAGAGGCCTTCCTGACTGGAAAGATGAAGAGAAACAGCATCTTG
GGGAAGAACTCTCAGACGTTTTGCTGTACCTTGTTAGGCTTGCTGATATTTGTGGGATTGATCTTGGCAAAGCAGCTCTGAGGAAGCTGGGGCTAAATGCCAAGAAATAC
CCAGTTAAGCTTTGCAAAGGCTCGTCAAGAAAACACACACAAATCAGCTGCCAAGACGATTGCAACGAAAATGGTGGAAAAGAAGAAGAAGACCCCACCAAACAGTGA

mRNA sequence

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Protein sequence

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MAEAAKREEVTLEELKTMMAEFARERDWDQFHSPRNLLLAMVGEVGELSEIFQWKGEVPRGLPDWKDEEKQHLGEELSDVLLYLVRLADICGIDLGKAALRKLGLNAKKY
PVKLCKGSSRKHTQISCQDDCNENGGKEEEDPTKQ

Lag0021772 (gene) of Sponge gourd (AG-4) v1 genome