CuGenDBv2

Gene ID	Lag0024168
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	dCTP pyrophosphatase 1
Genome location	chr10:934183..934921
RNA-Seq Expression	Lag0024168
Synteny	Lag0024168
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6607469.1 dCTP pyrophosphatase 1, partial [Cucurbita argyrosperma subsp. sororia]

1.1e-51

89.92

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEKT    NKDV LRELSERVAEFARVRGW+K+HSPRNLLLALVGEVGE+SEIFQWKGEVARGLPNWSAADKE L EELSDVLLYLVRLADVCG+DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQ
        ALSKILKNATKYPL PHQQ
Subjt:  ALSKILKNATKYPLIPHQQ

XP_022137081.1 dCTP pyrophosphatase 1-like [Momordica charantia]

1.4e-49

86.55

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEKT +Y + DVSL EL +RVAEFA  RGW+K H+PRNLLLALVGEVGELSEIFQWKGEVARGLPNWSA DKEHLEEELSDVLLYLVRLADVCGLDLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQ
        ALSKILKNA KYPLIPHQ+
Subjt:  ALSKILKNATKYPLIPHQQ

XP_022948897.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

3.6e-50

87.39

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEK     NKDV LRELSERVAEFARVRGW+K+HS RNLLLALVGEVGE+SEIFQWKGEVARGLPNWSAADKE L EELSDVLLYLVRLADVC +DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQ
        ALSKILKNATKYPL PHQQ
Subjt:  ALSKILKNATKYPLIPHQQ

XP_022998186.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

1.7e-52

86.99

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        M+K     NKDV L+ELSERVAEFARVRGW+K+HSPRNLLLALVGEVGE++EIFQWKGEVARGLPNWSAADKEHL EELSDVLLYLVRLADVCG+DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQPIQP
        ALSKILKNATKYPL PHQQ IQP
Subjt:  ALSKILKNATKYPLIPHQQPIQP

XP_038895217.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

7.5e-48

80.65

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEK    N ++VSLRELSERVAEF RVRGW+K+H+PRNLLLALVGEVGE+SEIFQWKGEV +GLP+WSAADKEHLE+ELSDV LYL+RLADVCGLDL +A
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPL-IPHQQPIQP
        ALSKILKNA+KYPL  PHQQ IQP
Subjt:  ALSKILKNATKYPL-IPHQQPIQP

TrEMBL top hits

e value

%identity

Alignment

A0A1R3HEG6 dCTP pyrophosphatase 1

3.1e-47

80.33

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Query:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL
        MEK+    N   KDVSL+EL +R+AEFA VRGWEK+HSPRNLLLALVGEVGELSEIFQWKGEVA+GLPNWSA DKEHLE+ELSDVLLYLV+LADVCGLDL
Subjt:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL

Query:  GRAALSKILKNATKYPLIPHQQ
        GRAALSKILKNA KYP++ +Q+
Subjt:  GRAALSKILKNATKYPLIPHQQ

A0A1R3KCG6 dCTP pyrophosphatase 1

6.2e-48

80.49

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Query:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL
        MEK+    N   KDVSL+EL +R+AEFA VRGWEK+HSPRNLLLALVGEVGELSEIFQWKGEVA+GLPNWSA DKEHLE+ELSDVLLYLV+LADVCGLDL
Subjt:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL

Query:  GRAALSKILKNATKYPLIPHQQP
        GRAALSKILKNA KYP++ +Q+P
Subjt:  GRAALSKILKNATKYPLIPHQQP

A0A6J1C5G1 dCTP pyrophosphatase 1

6.6e-50

86.55

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEKT +Y + DVSL EL +RVAEFA  RGW+K H+PRNLLLALVGEVGELSEIFQWKGEVARGLPNWSA DKEHLEEELSDVLLYLVRLADVCGLDLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQ
        ALSKILKNA KYPLIPHQ+
Subjt:  ALSKILKNATKYPLIPHQQ

A0A6J1GAI3 dCTP pyrophosphatase 1

1.7e-50

87.39

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEK     NKDV LRELSERVAEFARVRGW+K+HS RNLLLALVGEVGE+SEIFQWKGEVARGLPNWSAADKE L EELSDVLLYLVRLADVC +DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQ
        ALSKILKNATKYPL PHQQ
Subjt:  ALSKILKNATKYPLIPHQQ

A0A6J1K9K2 dCTP pyrophosphatase 1

8.3e-53

86.99

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        M+K     NKDV L+ELSERVAEFARVRGW+K+HSPRNLLLALVGEVGE++EIFQWKGEVARGLPNWSAADKEHL EELSDVLLYLVRLADVCG+DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQPIQP
        ALSKILKNATKYPL PHQQ IQP
Subjt:  ALSKILKNATKYPLIPHQQPIQP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

4.6e-24

50.94

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Query:  NKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKN
        + + +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   WS  ++  L+EELSD+L+YLV LA  C +DL +A L K+  N
Subjt:  NKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKN

Query:  ATKYPL
          +YP+
Subjt:  ATKYPL

Q91VC0 dCTP pyrophosphatase 1

7.1e-25

53.92

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Query:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY
        +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W   ++  L+EELSDVL+YLV LA  C +DL RA +SK+  N  +Y
Subjt:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY

Query:  PL
        P+
Subjt:  PL

Q9H773 dCTP pyrophosphatase 1

4.6e-24

55.45

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Query:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY
        +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   WS  ++  L+EELSDVL+YLV LA  C +DL  A LSK+  N  +Y
Subjt:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY

Query:  P
        P
Subjt:  P

Q9QY93 dCTP pyrophosphatase 1

2.7e-24

52.94

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Query:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY
        +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W   ++  L+EELSDVL+YLV LA  C +DL +A +SK+  N  +Y
Subjt:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY

Query:  PL
        P+
Subjt:  PL

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

4.0e-39

71.84

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Query:  VSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATK
        VSL+ LS+++ +FA+ R WEK+HSPRNLLLA+VGEVGELSEIFQWKGEVARG P+W   +K HL EELSDVLLYLVRL+D CG+DLG+AAL KI  NA K
Subjt:  VSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATK

Query:  YPL
        YP+
Subjt:  YPL

Sequences

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CDS sequence

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ATGGAGAAGACAAGTAGTTATAACAACAAAGATGTTTCTCTTAGAGAACTTAGTGAAAGAGTGGCAGAATTTGCTCGAGTTAGAGGTTGGGAAAAGTTTCACAGTCCTAG
AAATCTCCTTCTTGCCCTAGTCGGAGAAGTCGGGGAGCTGTCGGAGATATTCCAATGGAAAGGGGAAGTGGCGAGGGGGCTGCCGAACTGGTCCGCCGCCGACAAGGAAC
ATTTGGAAGAGGAGCTGTCGGACGTGTTGCTCTATTTGGTTCGGCTTGCAGATGTGTGTGGGCTTGATCTAGGCCGAGCTGCCCTTTCCAAGATCCTTAAAAATGCCACT
AAGTACCCTCTCATTCCTCACCAACAACCAATTCAACCCTAA

mRNA sequence

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Protein sequence

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MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNAT
KYPLIPHQQPIQP

Lag0024168 (gene) of Sponge gourd (AG-4) v1 genome