CuGenDBv2

Gene ID	Lag0024680
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	AICAR transformylase
Genome location	chr10:4890663..4897622
RNA-Seq Expression	Lag0024680
Synteny	Lag0024680
Gene Ontology terms	GO:0006189 - 'de novo' IMP biosynthetic process (biological process) GO:0005829 - cytosol (cellular component) GO:0003937 - IMP cyclohydrolase activity (molecular function) GO:0004643 - phosphoribosylaminoimidazolecarboxamide formyltransferase activity (molecular function)
InterPro domains	IPR002695 - Bifunctional purine biosynthesis protein PurH-like IPR011607 - Methylglyoxal synthase-like domain IPR016193 - Cytidine deaminase-like IPR024051 - AICAR transformylase, duplicated domain superfamily IPR036914 - Methylglyoxal synthase-like domain superfamily

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6584189.1 hypothetical protein SDJN03_20121, partial [Cucurbita argyrosperma subsp. sororia]

3.6e-236

70.22

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Query:  TVGIKTLSYKSEGVIVMFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVV
        +VGIK  S KSEGVI M  SVVAHSPATPITAIS  EP AR FLKE  PSPL++  +R SLH+ SV RR C T + MADGET+  SSKI   S S     
Subjt:  TVGIKTLSYKSEGVIVMFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVV

Query:  DKTHEGKFRLFPLGRVELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------
                          KKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGV VTKVEELTCFPEM D  +                    
Subjt:  DKTHEGKFRLFPLGRVELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------

Query:  IWTPNKHGIGKLMLVLLYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHV
        +    KHGI    +V    V+NL+  Y    S  + N                                              DDQQFRRKLAWKAFQHV
Subjt:  IWTPNKHGIGKLMLVLLYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHV

Query:  ASYDSAVSEWLWKQTVGDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE------------
        ASYDSAVSEWLWKQTVGDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE            
Subjt:  ASYDSAVSEWLWKQTVGDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE------------

Query:  ----------------LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLR
                        LAVKADPVSAFGGIVAFN+EVDE +  +EIREFRSPTDGETRMFYEIVVAPKYT+KGLEILRGKSKTLRILEA+KNEKGKLSLR
Subjt:  ----------------LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLR

Query:  QVGGGWLAQDSDDLVPQDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAW
        QVGGGWLAQDSDDLVPQDIQFNVVSGKAPQESEL+DAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIA+RKAGDEVKGAAL SDAFFPFAW
Subjt:  QVGGGWLAQDSDDLVPQDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAW

Query:  NDAVEEACQSGVGIIAEPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        NDAVEEACQSGVGIIAEPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
Subjt:  NDAVEEACQSGVGIIAEPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

XP_008440494.1 PREDICTED: bifunctional purine biosynthesis protein PurH [Cucumis melo]

4.4e-234

71.04

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Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MFRSVVAHSPATPITAIS  EP AR FLKEA P PLISL TRVSLH H +LR+ C T +AMADGET+  SSK+   SAS                     
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKK+LAFLGNGLQELGYTIVSTGGTASTLE+SGVHVTKVEE+TCFPEM D  +                    +    KHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y    S    N                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATA+QHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFNIEVDE +  +E+REFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEA KNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDI+FNVVSGKAPQESEL+DAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVGIIA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAIDCCNKYGVSL+FTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

XP_011652409.1 uncharacterized protein LOC101206006 [Cucumis sativus]

4.4e-234

71.04

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Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MFRSVVAHSPATPITAIS  EP A  FLKEA P PLISL TRVSLH HS+LR+ C T +AMADGET+A SSK+   SAS                     
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKK+LAFLGNGLQELGYTIVSTGGTASTLE+SGVHVTKVEE+TCFPEM D  +                    +    KHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y    S  + N                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPSFTVPL+LKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATA+QHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFNIEVDE +  +E+REFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEA KNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDI+FNVVSGKAPQE+EL+DAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVGIIA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

XP_022137602.1 uncharacterized protein LOC111009006 [Momordica charantia]

8.1e-236

71.99

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Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MFR V AHSPATPITAIS  EP AR+FLKEA+PSPL+SL TR+S+H+HSVLRRSC T +AMAD ET+ + +K ASSSAS                     
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGV VTKVEELT FPEM D  +                    +   NKHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y  V S  + D                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFNIEVDEV + +EIREFRSPTDGETRMFYEIVVAPKY+EKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDIQFN+VS KAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVGIIA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAI CCNKYGVSLVFTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

XP_038876982.1 bifunctional purine biosynthesis protein PurH [Benincasa hispida]

1.8e-235

71.36

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Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MFRSV AHSPATPITAISF EP AR FLKEA PSPL+S+ T V LH HSVLRR C T +AMADGET+  SSKI   SAS                     
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGV VTKVEELTCFPEM D  +                    +    KHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y    S  + N                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATA+QHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFN+EVDEV + +E+REFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEAS+NEKGKLSLRQVGGGWLAQD+DDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDI+ NVVSGKAPQESEL+DAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVGIIA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LRB7 AICAR transformylase

2.2e-234

71.04

Show/hide

Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MFRSVVAHSPATPITAIS  EP A  FLKEA P PLISL TRVSLH HS+LR+ C T +AMADGET+A SSK+   SAS                     
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKK+LAFLGNGLQELGYTIVSTGGTASTLE+SGVHVTKVEE+TCFPEM D  +                    +    KHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y    S  + N                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPSFTVPL+LKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATA+QHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFNIEVDE +  +E+REFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEA KNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDI+FNVVSGKAPQE+EL+DAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVGIIA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

A0A1S3B1V0 AICAR transformylase

2.2e-234

71.04

Show/hide

Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MFRSVVAHSPATPITAIS  EP AR FLKEA P PLISL TRVSLH H +LR+ C T +AMADGET+  SSK+   SAS                     
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKK+LAFLGNGLQELGYTIVSTGGTASTLE+SGVHVTKVEE+TCFPEM D  +                    +    KHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y    S    N                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSYVASGSKFDCN------------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATA+QHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFNIEVDE +  +E+REFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEA KNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDI+FNVVSGKAPQESEL+DAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVGIIA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAIDCCNKYGVSL+FTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

A0A6J1CAS3 AICAR transformylase

3.9e-236

71.99

Show/hide

Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MFR V AHSPATPITAIS  EP AR+FLKEA+PSPL+SL TR+S+H+HSVLRRSC T +AMAD ET+ + +K ASSSAS                     
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGV VTKVEELT FPEM D  +                    +   NKHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y  V S  + D                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFNIEVDEV + +EIREFRSPTDGETRMFYEIVVAPKY+EKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDIQFN+VS KAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVGIIA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAI CCNKYGVSLVFTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

A0A6J1GRT8 AICAR transformylase

9.0e-233

71.04

Show/hide

Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MF  V A SPATPIT ISF EP AR+FLKEATPSPL+SL TR SLH+HSV  R C   +AMADGE V LS+KI +SS S                    V
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKK+LAFLGNGLQELGYTIVSTGGTASTLETSGV VTKVEELT FPEM D  +                    +   +KHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y  V S  K D                                              DDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPS TVPLSLKSSLRYGENPHQKAAFYVDKS+SEVN GGIATAIQHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFN+EVDEV + +EIREFRSPTDGETRMFYEIVVAPKYT+KGLEILRGKSKTLRILEA+KNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
        QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVG+IA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

A0A6J1JVK7 AICAR transformylase

1.0e-231

71.04

Show/hide

Query:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV
        MF  V A SPATPITAISF EP AR+FLKEATPSPL+SL TR SLH+HSV  R C T +AMADGE V LS KI +SS S                    V
Subjt:  MFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRV

Query:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL
          KKLALISLSDKK+LAFLGNGLQELGYTIVSTGGTASTLETSGV VTKVE LT FPEM D  +                    +   +KHGIG   +V 
Subjt:  ELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVL

Query:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV
           V+NL+  Y  V S  K D                                              DDQ FRRKLAWKAFQHVASYDSAVSEWLWKQTV
Subjt:  LYLVINLWNSY--VASGSKFDCN----------------------------------------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTV

Query:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------
        GDKFPPS TVPLSLKSSLRYGENPHQKAAFYVDKS+SEVN GGIATAIQHHGKEMSYNNYLDADAAWNCVSE                            
Subjt:  GDKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------

Query:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP
        LAVKADPVSAFGGIVAFN+EVDEV + +EIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEA+KNEKGKLSLRQVGGGWLAQDSDDLVP
Subjt:  LAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVP

Query:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA
         DIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAAL SDAFFPFAWNDAVEEACQSGVG+IA
Subjt:  QDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIA

Query:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
Subjt:  EPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

SwissProt top hits

e value

%identity

Alignment

A9VRF5 Bifunctional purine biosynthesis protein PurH

5.5e-78

36.42

Show/hide

Query:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHGIGKLML----------------VLLYLV
        +KK AL+S+SDK  +     GL E G  ++STGGT   LE +G+ V  + E+T FPE+ D  +    PN HG G L +                 + ++V
Subjt:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHGIGKLML----------------VLLYLV

Query:  INLWN---------------------------SYVASGSKFDCNPWKPDD---------------QQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKF
        +NL+                               A   KF      P D               ++ +RKLA K F+H A+YD+ +S +L KQ +G++ 
Subjt:  INLWN---------------------------SYVASGSKFDCNPWKPDD---------------QQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKF

Query:  PPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVK
        P + TV    K  LRYGENPHQKA FY            +A A Q HGKE+SYNN  DADAA + V E                             A +
Subjt:  PPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVK

Query:  ADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEAS--KNEKGKLSLRQVGGGWLAQDSDDLVPQD
        ADPVS FGGI+A N E+D+ ++ +++ E          +F EIV+AP ++++ LE+L+ K K LR+L  +  K       L  V GG L Q+ D L   +
Subjt:  ADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEAS--KNEKGKLSLRQVGGGWLAQDSDDLVPQD

Query:  IQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEP
           ++ + + P E E +D + AW  VKHVKSNAIV+A +N  +G+G+GQ NR+ S +IA+ +AG++ +G+AL SDAFFP    D VEEA ++G+  I +P
Subjt:  IQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEP

Query:  GGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        GGSIRD D+I   + YG+++VFT VRHF+H
Subjt:  GGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

B7GFU2 Bifunctional purine biosynthesis protein PurH

5.5e-78

37.81

Show/hide

Query:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHGIGKL----------------MLVLLYLV
        +K+ A+IS+S+KK +      L ELG  I+STGGT   L   GV V  + ++T FPE+ D  +    PN HG G L                +  + ++V
Subjt:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHGIGKL----------------MLVLLYLV

Query:  INLWN---------------------------SYVASGSKFDCNPWKPDDQ---------------QFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKF
        +NL+                               A    +      P D                + RR LA K F+H A+YD+ ++++L    VG+ +
Subjt:  INLWN---------------------------SYVASGSKFDCNPWKPDDQ---------------QFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKF

Query:  PPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVK
        P + T+    K SLRYGENPHQ AAFY +K LS  +   IA A Q HGKE+SYNN  DA+AA   V+E                             A +
Subjt:  PPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVK

Query:  ADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEIL-RGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVPQDI
        ADP S FGGIVA N EVDE  + K              +F EIV+AP +TE+ LEIL R K+  L  ++     K +  +  V GG L QD D     D 
Subjt:  ADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEIL-RGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVPQDI

Query:  QFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPG
           VV+ + P E E  +  FAW  VKHVKSNAIV+AKN   +G+G+GQ NR+ + +IA+ +AGD  KGA L SDAFFP   +D VE A Q+GV  I +PG
Subjt:  QFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPG

Query:  GSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        GSIRD D+I   N+YG+++VFT VRHF+H
Subjt:  GSIRDPDAIDCCNKYGVSLVFTNVRHFRH

C3PBN4 Bifunctional purine biosynthesis protein PurH

9.4e-78

36.11

Show/hide

Query:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHG--------------IGKL-MLVLLYLVI
        +KK AL+S+SDK  +     GL E G  ++STGGT   LE +G+ V  + E+T FPE+ D  +    PN HG              + +L M  + ++V+
Subjt:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHG--------------IGKL-MLVLLYLVI

Query:  NLWN---------------------------SYVASGSKFDCNPWKPDD---------------QQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFP
        NL+                               A   KF      P D               ++ +RKLA K F+H A+YD+ +S +L +Q +G++ P
Subjt:  NLWN---------------------------SYVASGSKFDCNPWKPDD---------------QQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFP

Query:  PSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVKA
         + TV    K  LRYGENPHQKA FY            +A A Q HGKE+SYNN  DADAA + V E                             A +A
Subjt:  PSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVKA

Query:  DPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEAS--KNEKGKLSLRQVGGGWLAQDSDDLVPQDI
        DPVS FGGI+A N E+D+ ++ +++ E          +F EI++AP ++++ LE+L+ K K LR+L  +  K       L  V GG L Q+ D L   + 
Subjt:  DPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEAS--KNEKGKLSLRQVGGGWLAQDSDDLVPQDI

Query:  QFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPG
          ++ + + P E E +D + AW  VKHVKSNAIV+AK++  +G+G+GQ NR+ S +IA+ +AG++ +G+AL SDAFFP    D VEEA ++G+  I +PG
Subjt:  QFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPG

Query:  GSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        GSIRD D+I   + YG+++VFT VRHF+H
Subjt:  GSIRDPDAIDCCNKYGVSLVFTNVRHFRH

Q73EN1 Bifunctional purine biosynthesis protein PurH

7.2e-78

35.85

Show/hide

Query:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHGIGKLML----------------VLLYLV
        +KK AL+S+SDK  +     GL E G  ++STGGT   LE +G+ V  + E+T FPE+ D  +    PN HG G L +                 + +++
Subjt:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI-IWTPNKHGIGKLML----------------VLLYLV

Query:  INLWN---------------------------SYVASGSKFDCNPWKPDD---------------QQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKF
        +NL+                               A   KF      P D               ++ +RKLA K F+H A+YD+ +S +L +Q +G++ 
Subjt:  INLWN---------------------------SYVASGSKFDCNPWKPDD---------------QQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKF

Query:  PPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVK
        P + TV    K  LRYGENPHQKA FY            +A A Q HGKE+SYNN  DADAA + V E                             A +
Subjt:  PPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVK

Query:  ADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEAS--KNEKGKLSLRQVGGGWLAQDSDDLVPQD
        ADPVS FGGI+A N E+D+ S+ +++ E          +F EI++AP ++++ LE+L+ K K LR+L  +  K+      L  V GG L Q+ D L   +
Subjt:  ADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEAS--KNEKGKLSLRQVGGGWLAQDSDDLVPQD

Query:  IQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEP
           ++ + + P E E +D + AW  VKHVKSNAIV+AK++  +G+G+GQ NR+ S +IA+ +AG++ +G+AL SDAFFP    D +EEA ++G+  I +P
Subjt:  IQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEP

Query:  GGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        GGSIRD D+I   + YG+++VFT VRHF+H
Subjt:  GGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

Q8CXK7 Bifunctional purine biosynthesis protein PurH

3.2e-78

36.67

Show/hide

Query:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVLL
        + K ALIS+SDK ++     GL+E G+ I+STGGT  ++  +G+ VT V+E+T FPEM D  +                    +    +HGI  + LV +
Subjt:  LKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVLL

Query:  YL--------------------------------VINLWNSYVASGSKFDCN------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFP
         L                                  N  +  V +G   D N        + D  +FR++LA K F+H ASYD+ ++ +   QT  +++P
Subjt:  YL--------------------------------VINLWNSYVASGSKFDCN------PWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFP

Query:  PSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVKA
         S+TV       LRYGENPHQ+AAFY +   S      +ATA Q HGKE+SYNN  D +AA   V E                             A +A
Subjt:  PSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEL----------------------------AVKA

Query:  DPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLS--LRQVGGGWLAQDSDDLVPQDI
        DP S FGGIVA N  VD  ++           +  +++F EIVVAP +  + LEIL  K K +R+LE       K S  L  V GG L Q  D     + 
Subjt:  DPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLS--LRQVGGGWLAQDSDDLVPQDI

Query:  QFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPG
           VV+ K P E E+ D  FAW  VKHVKSNAIV+AK++  +G+G+GQ NR+ +  IA+++AGD+ +GA L SDAFFP    D VE A ++G+  I +PG
Subjt:  QFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPG

Query:  GSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        GS RD D++D CN++G+++V+T VRHF+H
Subjt:  GSIRDPDAIDCCNKYGVSLVFTNVRHFRH

Arabidopsis top hits

e value

%identity

Alignment

AT2G35040.1 AICARFT/IMPCHase bienzyme family protein

5.9e-192

60.83

Show/hide

Query:  ATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRVELKKLALISL
        AT ++A S    C     K   P      + R SL        S    RAMA+ +T   +   +S S+ E                       K ALISL
Subjt:  ATPITAISFREPCARAFLKEATPSPLISLITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRVELKKLALISL

Query:  SDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVLLYLVINLWNS
        SDK+DLA LGNGLQELGYTIVSTGGTASTLE +GV VTKVE+LT FPEM D  +                    +   N+HGIG   +V    V+NL+  
Subjt:  SDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVLLYLVINLWNS

Query:  Y----VASGSKFDCNPWKPD--------------------------------------DQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVG-DKFPPSFT
        Y       G  F+      D                                      DQQFRRKLAWKAFQHVA+YDSAVSEWLWKQT G +KFPPSFT
Subjt:  Y----VASGSKFDCNPWKPD--------------------------------------DQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVG-DKFPPSFT

Query:  VPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------LAVKADPVS
        VPL LKSSLRYGENPHQKAAFYVDKSL+EVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE                            LAVKADPVS
Subjt:  VPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------LAVKADPVS

Query:  AFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVPQDIQFNVVS
        AFGGIVAFN+EVDEV + +EIREFRSPTDGETRMFYEIVVAPKYT KGLE+L+GKSKTLRILEA KN++GKLSLRQVGGGWLAQDSDDL P+DI FN VS
Subjt:  AFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVPQDIQFNVVS

Query:  GKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPGGSIRDP
         K P ESEL DA+FAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNR+ESLRIA +KAG+E KGAAL SDAFFPFAW DAVEEACQ G+G+IAEPGGSIRD 
Subjt:  GKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPGGSIRDP

Query:  DAIDCCNKYGVSLVFTNVRHFRH
        DAIDCC KYGVSL+FTNVRHFRH
Subjt:  DAIDCCNKYGVSLVFTNVRHFRH

AT2G35040.2 AICARFT/IMPCHase bienzyme family protein

1.2e-192

67.8

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Query:  KKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVLLY
        +K ALISLSDK+DLA LGNGLQELGYTIVSTGGTASTLE +GV VTKVE+LT FPEM D  +                    +   N+HGIG   +V   
Subjt:  KKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTKVEELTCFPEMKDQSI--------------------IWTPNKHGIGKLMLVLLY

Query:  LVINLWNSY----VASGSKFDCNPWKPD--------------------------------------DQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVG-
         V+NL+  Y       G  F+      D                                      DQQFRRKLAWKAFQHVA+YDSAVSEWLWKQT G 
Subjt:  LVINLWNSY----VASGSKFDCNPWKPD--------------------------------------DQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVG-

Query:  DKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------L
        +KFPPSFTVPL LKSSLRYGENPHQKAAFYVDKSL+EVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE                            L
Subjt:  DKFPPSFTVPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSE----------------------------L

Query:  AVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVPQ
        AVKADPVSAFGGIVAFN+EVDEV + +EIREFRSPTDGETRMFYEIVVAPKYT KGLE+L+GKSKTLRILEA KN++GKLSLRQVGGGWLAQDSDDL P+
Subjt:  AVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLEILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVPQ

Query:  DIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAE
        DI FN VS K P ESEL DA+FAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNR+ESLRIA +KAG+E KGAAL SDAFFPFAW DAVEEACQ G+G+IAE
Subjt:  DIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEVKGAALTSDAFFPFAWNDAVEEACQSGVGIIAE

Query:  PGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH
        PGGSIRD DAIDCC KYGVSL+FTNVRHFRH
Subjt:  PGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

Sequences

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CDS sequence

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ATGATCGCCGAAAAAGCGATTGGGGACCAGCAATGGTCTCCGGCTTTAGGGTTAGAGAAGAAGAAGATGTTAAAGATGGAGATTGAGGTTGATGAAGAAGATGAAAATGA
TGCAAGTTTAATGGGAATGGAGGAAGAAAATGATGAAGATGAAGATGAAAATAAAACAGTTGGTATCAAGACACTAAGCTACAAAAGCGAAGGAGTGATAGTGATGTTTA
GGTCTGTTGTTGCCCATTCGCCTGCCACGCCTATCACTGCTATTTCATTTCGAGAACCCTGTGCCCGGGCCTTTCTCAAGGAAGCCACTCCTTCGCCTCTTATTTCTTTA
ATTACTCGGGTCTCTCTCCACTCTCATTCTGTGCTACGACGGTCGTGCTGTACTCCCAGAGCCATGGCTGATGGTGAGACCGTCGCTCTTTCTTCAAAGATCGCCTCATC
ATCTGCTTCTGAGATGGACGTTGTGGATAAGACACATGAAGGGAAGTTTCGTTTGTTTCCGCTAGGGAGAGTTGAGTTGAAAAAGCTAGCTCTGATATCATTGTCAGACA
AGAAAGATCTTGCATTTCTAGGAAATGGGCTTCAAGAATTGGGCTATACAATTGTTTCAACTGGTGGAACAGCATCTACATTGGAAACTTCTGGGGTACACGTTACTAAA
GTGGAGGAGCTTACATGTTTTCCTGAAATGAAAGACCAAAGCATCATATGGACGCCTAATAAACATGGAATTGGTAAGTTAATGCTTGTTCTATTGTATCTTGTGATCAA
TCTCTGGAATTCTTATGTGGCCAGTGGCTCTAAGTTTGACTGCAATCCATGGAAACCAGATGATCAACAATTTCGCAGAAAGCTTGCTTGGAAGGCATTTCAACATGTAG
CTTCTTATGATTCTGCCGTCTCAGAATGGCTGTGGAAGCAGACTGTTGGGGATAAATTCCCTCCCAGCTTTACTGTGCCTCTCTCCCTCAAAAGTTCTCTTCGCTACGGG
GAAAATCCTCATCAGAAGGCTGCCTTTTATGTTGATAAGAGTCTTTCTGAGGTCAATGCTGGTGGTATTGCAACAGCAATCCAACACCATGGAAAGGAGATGTCATATAA
TAACTACTTAGATGCCGATGCAGCTTGGAACTGTGTATCAGAGTTAGCTGTAAAAGCTGATCCTGTGAGTGCTTTTGGTGGCATTGTAGCCTTCAACATAGAAGTTGATG
AGGTTAGTTCTTGCAAGGAAATTCGGGAATTTAGAAGTCCTACTGATGGTGAAACTCGGATGTTTTATGAGATTGTTGTTGCACCCAAGTACACAGAGAAAGGGCTCGAG
ATCTTGCGTGGGAAATCGAAGACTCTGCGAATTCTTGAGGCAAGCAAAAATGAGAAAGGAAAACTCTCACTCAGGCAAGTTGGTGGGGGGTGGTTAGCACAGGATTCTGA
TGATTTGGTTCCCCAAGATATACAATTTAACGTAGTCTCTGGAAAGGCTCCTCAAGAGAGTGAGCTTCAAGATGCAGAGTTTGCATGGTTGTGTGTCAAGCATGTTAAGA
GCAATGCCATTGTGATAGCAAAGAATAACTGTATGTTGGGTATGGGCAGCGGGCAACCAAATCGTCTCGAGAGTTTGAGGATAGCCTTGAGGAAAGCAGGGGATGAGGTC
AAAGGAGCGGCTTTGACTAGTGATGCATTCTTCCCATTTGCTTGGAATGATGCAGTGGAAGAGGCATGCCAGAGCGGAGTAGGTATTATTGCTGAGCCTGGGGGCAGCAT
TCGAGATCCCGATGCTATCGACTGCTGCAACAAGTATGGTGTGTCTCTCGTCTTCACTAACGTGAGGCATTTCAGGCACTGA

mRNA sequence

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Protein sequence

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MIAEKAIGDQQWSPALGLEKKKMLKMEIEVDEEDENDASLMGMEEENDEDEDENKTVGIKTLSYKSEGVIVMFRSVVAHSPATPITAISFREPCARAFLKEATPSPLISL
ITRVSLHSHSVLRRSCCTPRAMADGETVALSSKIASSSASEMDVVDKTHEGKFRLFPLGRVELKKLALISLSDKKDLAFLGNGLQELGYTIVSTGGTASTLETSGVHVTK
VEELTCFPEMKDQSIIWTPNKHGIGKLMLVLLYLVINLWNSYVASGSKFDCNPWKPDDQQFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFPPSFTVPLSLKSSLRYG
ENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSELAVKADPVSAFGGIVAFNIEVDEVSSCKEIREFRSPTDGETRMFYEIVVAPKYTEKGLE
ILRGKSKTLRILEASKNEKGKLSLRQVGGGWLAQDSDDLVPQDIQFNVVSGKAPQESELQDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALRKAGDEV
KGAALTSDAFFPFAWNDAVEEACQSGVGIIAEPGGSIRDPDAIDCCNKYGVSLVFTNVRHFRH

Lag0024680 (gene) of Sponge gourd (AG-4) v1 genome