CuGenDBv2

Gene ID	Lag0027691
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog
Genome location	chr8:3591340..3596251
RNA-Seq Expression	Lag0027691
Synteny	Lag0027691
Gene Ontology terms	GO:0006203 - dGTP catabolic process (biological process) GO:0005634 - nucleus (cellular component) GO:0005524 - ATP binding (molecular function) GO:0008832 - dGTPase activity (molecular function)
InterPro domains	IPR003607 - HD/PDEase domain IPR006674 - HD domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6588963.1 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like protein, partial [Cucurbita argyrosperma subsp. sororia]

4.3e-261

94.49

Show/hide

Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGAS+IDELSLAP +NFN SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLG+T+MVYPGAVHSRFEHSLGVYWLA EAV KL+ YQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLP+VLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVK+MILSSSEFT+PKGSREKGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRL+ETMRVIDDEICYKAKDYLTIHKLF+TRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHDP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        SQYWKLDDSVVKTIETASDQELKESRDLIL+IRRRNLYQFCNEYAVPK+KLENFKDVTAKDI+CSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPLER  F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

XP_022928109.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog [Cucurbita moschata]

1.6e-260

94.49

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Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGAS+IDELSLAP +NFN SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLG+T+MVYPGAVHSRFEHSLGVYWLA EAV KL+ YQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLP+VLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVK+MILSSSEFT+PKGSREKGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDYIVRDCRACGLGCNF FQRL+ETMRVIDDEICYKAKDYLTIHKLF+TRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHDP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        SQYWKLDDSVVKTIETASDQELKESRDLIL+IRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPLER  F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

XP_022989158.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog [Cucurbita maxima]

5.1e-262

95.13

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Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGAS+IDELSLAP +NFN SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVT+MVYPGAVHSRFEHSLGVYWLA EAV KL+ YQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVK+MILSSSEFT+PKGSREKGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRL+ETMRVIDDEICYKAKDYLTIHKLF+TRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHDP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        SQYWKLDDSVVKTIETASDQELKESRDLIL+IRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPLER  F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

XP_023531708.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X1 [Cucurbita pepo subsp. pepo]

2.8e-260

94.71

Show/hide

Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGAS+IDELSLAP +NFN SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLG+T+MVYPGAVHSRFEHSLGVYWLA EAV KL+ YQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPK-GSREKGFLYDIV
        ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVK+MILSSSEFT+PK GSREKGFLYDIV
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPK-GSREKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRL+ETMRVIDDEICYKAKDYLTIHKLF+TRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHD

Query:  PSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFS
        PSQYWKLDDSVVKTIETASDQELKESRDLIL+IRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPLER  
Subjt:  PSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFS

Query:  FVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
        F +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
Subjt:  FVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

XP_023531709.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X2 [Cucurbita pepo subsp. pepo]

1.1e-261

94.92

Show/hide

Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGAS+IDELSLAP +NFN SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLG+T+MVYPGAVHSRFEHSLGVYWLA EAV KL+ YQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVK+MILSSSEFT+PKGSREKGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRL+ETMRVIDDEICYKAKDYLTIHKLF+TRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHDP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        SQYWKLDDSVVKTIETASDQELKESRDLIL+IRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPLER  F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LFH1 HD domain-containing protein

1.3e-252

91.72

Show/hide

Query:  MGASLIDELSLAPAYNFNSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAE
        MGASL DEL L P  NFNS  D+RCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVT+MVYPGAVHSRFEHSLGVYWLAG+AV KLKNYQGAE
Subjt:  MGASLIDELSLAPAYNFNSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAE

Query:  LDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVAN
        LDID  DIQTVKLAGLLHDVGHGPFSHLFEREFL +VLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEF +PKGSREKGFLYDIVAN
Subjt:  LDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVAN

Query:  GRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDPS
        GRNGIDVDKFDYIVRDCRACGLGCNF F+RL+ETMRVIDDEICYKA DYLTIHKLFATRADLYRTVY HPKVKAIELM+VDAL+KANDYL++SS+IHDPS
Subjt:  GRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDPS

Query:  QYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSFV
        QYWKLDDS+VKTIETAS++ELKESRDLILRIRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGV L+EEDVAVSNVRIDLTRGR NPLER  F 
Subjt:  QYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSFV

Query:  QDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
        +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATP+KKKRRI
Subjt:  QDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

A0A6J1DYF2 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X1

3.2e-254

Show/hide

Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGASL DELSLAP ++FN SFQDLRC KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLG ++MVYPGAVHSRFEHSLGVYWLAGEA+ KLKNYQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDH DIQTVKLAGLLHDVGHGPFSHLFEREF+PQV S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRVKEMILSSSEFT+PKGSR KGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVK---AIELMIVDALVKANDYLEISSHI
        NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRL+ETMRVIDDEICYKAKDYLT+HKLFATRADLYRTVYMHPKVK   AIELM+VDAL+KANDYLEISSHI
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVK---AIELMIVDALVKANDYLEISSHI

Query:  HDPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLER
        HDPSQYWKLDD++VKTIETA DQELKESRDLILRIRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPL+R
Subjt:  HDPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLER

Query:  FSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
          F +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATPEKKKRRI
Subjt:  FSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

A0A6J1E0V4 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X2

7.6e-256

92.58

Show/hide

Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGASL DELSLAP ++FN SFQDLRC KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLG ++MVYPGAVHSRFEHSLGVYWLAGEA+ KLKNYQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDH DIQTVKLAGLLHDVGHGPFSHLFEREF+PQV S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRVKEMILSSSEFT+PKGSR KGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRL+ETMRVIDDEICYKAKDYLT+HKLFATRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHDP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        SQYWKLDD++VKTIETA DQELKESRDLILRIRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPL+R  F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATPEKKKRRI
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

A0A6J1EJX3 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog

7.9e-261

94.49

Show/hide

Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGAS+IDELSLAP +NFN SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLG+T+MVYPGAVHSRFEHSLGVYWLA EAV KL+ YQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLP+VLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVK+MILSSSEFT+PKGSREKGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDYIVRDCRACGLGCNF FQRL+ETMRVIDDEICYKAKDYLTIHKLF+TRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHDP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        SQYWKLDDSVVKTIETASDQELKESRDLIL+IRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPLER  F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

A0A6J1JPF8 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog

2.4e-262

95.13

Show/hide

Query:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGAS+IDELSLAP +NFN SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVT+MVYPGAVHSRFEHSLGVYWLA EAV KL+ YQGA
Subjt:  MGASLIDELSLAPAYNFN-SFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVK+MILSSSEFT+PKGSREKGFLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRL+ETMRVIDDEICYKAKDYLTIHKLF+TRADLYRTVYMHPKVKAIELM+VDAL+KANDYLEISSHIHDP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        SQYWKLDDSVVKTIETASDQELKESRDLIL+IRRRNLYQFCNEYAVPK+KLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPLER  F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

SwissProt top hits

e value

%identity

Alignment

B0G107 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog

9.1e-89

40.05

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Query:  NFNSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAG
        N   +   + SK ++D +HG++ +    + FIDTEQFQRLR+LKQ+G T+ V+P A HSRFEHS+GV  LAG+ + ++K  Q  EL+I   + + V++AG
Subjt:  NFNSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAG

Query:  LLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID-IDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVANGRNGIDVDKFDYIV
        L HD+GHGPFSH FE  ++ Q+     + HE MS+KM++ I+D+H +D  DS  IK +  +I       +PK   E+ F+YDIVAN RN +DVDKFDY+ 
Subjt:  LLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID-IDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVANGRNGIDVDKFDYIV

Query:  RDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDPSQYWKLDDSVVKTIE
        RD    G      FQRL+E  +VIDD+IC+ +K+   +++LF TR  L++ VY H   K+IE MI DA  +A+ +L+IS  + DP ++  L DS+++ IE
Subjt:  RDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDPSQYWKLDDSVVKTIE

Query:  TASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSFVQDYESNDKFKISDD
        T+ + EL++SR +I  IR RNLY+F +E  V  +K+    D  A+DI  ++   G+L  E D+ V N++++      +P++   F   Y+S   F I  +
Subjt:  TASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSFVQDYESNDKFKISDD

Query:  RISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGI
          SHL+P  +Q+  +R++ +  E  E +  AF    LK + +
Subjt:  RISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGI

Q0VCA5 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1.7e-71

35.03

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Query:  NSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLL
        N  QD    K ++D +HG+I   PL ++ IDT QFQRLR +KQLG    V+PGA H+RFEHSLGV +LAG  V +L   Q  EL I   DI  V++AGL 
Subjt:  NSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLL

Query:  HDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID--------IDSGMIKRVKEMIL--------SSSEFTQPKGSREKGFLYDIVANG
        HD+GHGPFSH+F+  F+P      +W+HE  SV M +H+++ + +         I    I  +KE I          +S++      +EK FLY+IVAN 
Subjt:  HDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID--------IDSGMIKRVKEMIL--------SSSEFTQPKGSREKGFLYDIVANG

Query:  RNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVID----DEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE------
        RNGIDVDK+DY  RDC   G+  +F ++R L+  RV +      IC + K+   ++ +F TR  L+R  Y H     I+ MI DA +KA+D++E      
Subjt:  RNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVID----DEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE------

Query:  ----ISSHIHDPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEY--AVPKEKLENFKDVTAKDIVCSQKNGGVLLQ----EEDVAVSN
            IS+ I D   + KL D++   I  ++D  L ++R ++ +I  RNLY+F  E    + + K EN++ +  +  V S K   V L+     ED+ V  
Subjt:  ----ISSHIHDPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEY--AVPKEKLENFKDVTAKDIVCSQKNGGVLLQ----EEDVAVSN

Query:  VRIDLTRGRNNPLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPE--LVEAISEAFENFQLKTYGIKTQVHATPEKKKRR
        + +D      NP++   F    + +    I+ +++S  LP ++ + ++RVY KK +   + A  + F ++ L     K Q+   P +K ++
Subjt:  VRIDLTRGRNNPLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPE--LVEAISEAFENFQLKTYGIKTQVHATPEKKKRR

Q502K2 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

7.8e-72

38.31

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Query:  KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLLHDVGHGPFS
        K  +D +HG+I L PL L FIDT QFQRLR +KQLG T +V+PGA H+RFEHS+GV +LAG  V K  N +  EL I   DI  V++AGL HD+GHGPFS
Subjt:  KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLLHDVGHGPFS

Query:  HLFEREFLPQVLSGYEWSHELMSVKMVDHIVDE--------HH--------IDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVANGRNGIDVDKF
        H+F+  F+P+     +W HE+ SV+M DH+V+         HH        I I   +   ++  +L  S++       EK FLY++VAN RNGIDVDK+
Subjt:  HLFEREFLPQVLSGYEWSHELMSVKMVDHIVDE--------HH--------IDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVANGRNGIDVDKF

Query:  DYIVRDCRACGLGCNFQFQRLLETMRVID----DEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE----------ISSHI
        DY  RDC   G+  NF +QR L   RV +      IC + K+   ++ +F TR  L+R  Y H     IE MI +A +KA+ +++          ISS I
Subjt:  DYIVRDCRACGLGCNFQFQRLLETMRVID----DEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE----------ISSHI

Query:  HDPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYA------VPKEKLENFKDVTAKDIVCSQKNG--GVLLQEEDVAVSNVRIDLTR
         D   Y KL D + + I  +S  EL E+R ++  I  R LY+   +        V +EKL ++    AK++  S+  G  G L+  ED  VS + +D   
Subjt:  HDPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYA------VPKEKLENFKDVTAKDIVCSQKNG--GVLLQEEDVAVSNVRIDLTR

Query:  GRNNPLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPE
           NP+    F    +     KI   ++S LLP  + + ++RVY KK +
Subjt:  GRNNPLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPE

Q5ZJL9 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1.2e-75

37.89

Show/hide

Query:  KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLLHDVGHGPFS
        K  +D VHG+I + PL ++ IDT QFQRLR +KQLG T  V+PGA H+RFEHSLGV +LAG  V +LK  Q  ELDI   DI  V++AGL HD+GHGPFS
Subjt:  KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLLHDVGHGPFS

Query:  HLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID--------IDSGMIKRVKEMILSSSEFTQPKGS-------REKGFLYDIVANGRNGIDVDKFD
        H+F+  F+P    G  W HE  SV+M +H++  + ++        I    I  +KE I    + T  + S       +EK FLY+IVAN +NGIDVDK+D
Subjt:  HLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID--------IDSGMIKRVKEMILSSSEFTQPKGS-------REKGFLYDIVANGRNGIDVDKFD

Query:  YIVRDCRACGLGCNFQFQRLLETMRVID----DEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE----------ISSHIH
        Y  RDC   G+  NF ++RL++  RV +      IC + K+   ++ +F TR  L+R  Y H     IE+MI +A  KA+ + +          IS+ + 
Subjt:  YIVRDCRACGLGCNFQFQRLLETMRVID----DEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE----------ISSHIH

Query:  DPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPK--EKLENFKDVTAKDIVCSQKN---GGVLLQEEDVAVSNVRIDLTRGRNN
        D   Y KL D++   I  +S  EL E+R+++ +I RR LY+F  E    K  E  ++  D  A DI  S+       V L  ED  V  V +D      N
Subjt:  DPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPK--EKLENFKDVTAKDIVCSQKN---GGVLLQEEDVAVSNVRIDLTRGRNN

Query:  PLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKK--PELVEAISEAFENFQLKTYGIKTQ------VHATPEKK
        P++   F    + +   KIS +++S LLP ++ + ++RVY K+  P +V A  + F  + +K    K Q       H TP K+
Subjt:  PLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKK--PELVEAISEAFENFQLKTYGIKTQ------VHATPEKK

Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1.4e-73

38.15

Show/hide

Query:  KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLLHDVGHGPFS
        K ++D +HG+I L PL ++ IDT QFQRLR +KQLG    V+PGA H+RFEHSLGV +LAG  VH L   Q  EL I   D+  V++AGL HD+GHGPFS
Subjt:  KHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQTVKLAGLLHDVGHGPFS

Query:  HLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID--------IDSGMIKRVKEMILSSSE------FTQPKGSRE-KGFLYDIVANGRNGIDVDKFD
        H+F+  F+P      +W+HE  SV M +H+++ + I         I    I  +KE I+   E          KG  E K FLY+IV+N RNGIDVDK+D
Subjt:  HLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHID--------IDSGMIKRVKEMILSSSE------FTQPKGSRE-KGFLYDIVANGRNGIDVDKFD

Query:  YIVRDCRACGLGCNFQFQRLLETMRV--IDDE--ICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE----------ISSHIH
        Y  RDC   G+  NF ++R ++  RV  +D+E  IC + K+   ++ +F TR  L+R  Y H     I+ MI DA +KA+DY+E          IS+ I 
Subjt:  YIVRDCRACGLGCNFQFQRLLETMRV--IDDE--ICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLE----------ISSHIH

Query:  DPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVP---KEKLENFKDVTAKDIVCSQKNG--GVLLQEEDVAVSNVRIDLTRGRNN
        D   Y KL D++   I  ++D +LK++R+++ +I  RNL+++  E       K K E+++ +  K++  ++      V L+ ED  V  + +D      N
Subjt:  DPSQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVP---KEKLENFKDVTAKDIVCSQKNG--GVLLQEEDVAVSNVRIDLTRGRNN

Query:  PLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKK
        P++  SF      N   +I+ +++S LLP  + + ++RVY KK
Subjt:  PLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKK

Arabidopsis top hits

e value

%identity

Alignment

AT5G40270.1 HD domain-containing metal-dependent phosphohydrolase family protein

3.0e-212

74.15

Show/hide

Query:  MGASLIDELSLAPAYNFNS-FQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA
        MGA   + LS  P ++  +   +LR SKHV+DNVHGNIYLDPL LKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGE   +LKN+QG 
Subjt:  MGASLIDELSLAPAYNFNS-FQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGA

Query:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA
        EL ID+ D+QTV+LAGLLHD+GHGPFSH+FEREFLP+V+S  +WSHELMSV M+DH+VD HHIDID+ M+KRVK+MIL+S+EF+Q KG+ EK FLYDIVA
Subjt:  ELDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVA

Query:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP
        NGRNGIDVDKFDY+VRD RACGLG NFQFQRL ETMRV+D+EIC++AK+YL++HKLFATRADLYRTVY H KVKAIELMIVDA+VKAN++LEISS I+DP
Subjt:  NGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDP

Query:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF
        S+YWKLDD+++KTIE A D EL E+++LILR+RRR LYQFCNEYAVPK+K+++FK VT +DI+CSQK+  + L+EED+AV+NV+IDL RGR NPLE  +F
Subjt:  SQYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSF

Query:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI
         +DY+S +KF I +DR+SHLLPT+YQDMIVRVY+KKPELVEA+SEAFENFQ++TYGIK QVHATPEKKKRR+
Subjt:  VQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQVHATPEKKKRRI

AT5G40290.1 HD domain-containing metal-dependent phosphohydrolase family protein

1.9e-198

72.17

Show/hide

Query:  MGASLIDELSLAPAYNFNSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAE
        MG    ++LS  PA       +LR SKHVHDNVHGNIYLDPL LKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGE V +LK +QG E
Subjt:  MGASLIDELSLAPAYNFNSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAE

Query:  LDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVAN
        L ID++D+QTV+LAGLLHD+GHGPFSH+FEREFLP+V+SG +WSHELMS+ M+D+IVD HHID+D+ M+KRVK+MIL+S+E ++ KG+ EK FLYDIVAN
Subjt:  LDIDHNDIQTVKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVAN

Query:  GRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDPS
        GRNGIDVDKFDYIVRD RACGLGCNFQFQRL E MRVID+EICY AK+Y T+HKLFATRADL  TVYMHPK  AIELMIVDA+VKAN+ LEISS I+DPS
Subjt:  GRNGIDVDKFDYIVRDCRACGLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDPS

Query:  QYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSFV
        QYWKLDD+++KTIE + D EL E+++LILR+ RR+LYQFCNEYAVPK+K+++FK +T +DI+C          EED+AV+NV+IDL RGR NPLE  +F 
Subjt:  QYWKLDDSVVKTIETASDQELKESRDLILRIRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSFV

Query:  QDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQV
        +DY S +KF I +DR+SHLLPT+YQ+MIVRVY+KKPELVEA+SEAFENFQ++TYGIK QV
Subjt:  QDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKTYGIKTQV

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGGTGCGTCTCTCATCGACGAACTGTCGCTCGCTCCGGCTTACAACTTCAATTCCTTCCAGGATCTCCGCTGCTCCAAGCACGTCCATGACAACGTTCACGGCAACAT
TTACCTCGATCCGCTTTCTTTGAAGTTTATTGATACCGAGCAGTTTCAGAGGCTTCGTGAATTGAAACAGCTTGGTGTGACGAATATGGTCTATCCGGGAGCTGTACATT
CTAGGTTTGAACACTCGTTAGGAGTGTATTGGCTTGCCGGAGAAGCTGTTCACAAGCTTAAAAATTACCAAGGAGCAGAGCTTGATATTGATCACAATGATATACAGACA
GTGAAACTTGCTGGTCTTCTGCACGATGTGGGCCATGGGCCTTTTAGTCACCTGTTTGAGCGCGAGTTCCTCCCCCAGGTTTTGAGTGGATATGAATGGTCTCATGAACT
TATGTCGGTTAAGATGGTTGACCATATTGTTGATGAACACCACATTGATATTGATTCTGGAATGATAAAAAGAGTCAAGGAGATGATACTATCTAGCTCTGAATTTACTC
AGCCAAAGGGTTCAAGGGAGAAGGGCTTCTTGTACGACATTGTTGCAAATGGACGAAATGGAATTGATGTAGACAAGTTTGATTATATCGTTCGTGATTGCCGAGCTTGT
GGTCTCGGATGCAACTTTCAGTTTCAGAGGCTATTGGAGACTATGCGAGTTATAGATGATGAAATTTGCTATAAGGCGAAGGACTATCTTACAATTCACAAGTTGTTTGC
TACTCGGGCTGATTTATATCGAACAGTTTATATGCACCCAAAAGTTAAGGCCATTGAGCTTATGATAGTTGATGCTCTGGTGAAGGCGAATGATTATCTGGAAATTTCAT
CTCACATCCATGATCCCTCCCAGTACTGGAAGTTAGATGATTCTGTAGTTAAGACAATTGAGACTGCTTCAGACCAAGAATTAAAGGAATCTAGAGATCTGATCTTGCGA
ATCCGCAGAAGAAATCTCTACCAGTTTTGTAATGAATATGCCGTCCCAAAAGAAAAACTGGAAAATTTCAAGGATGTAACTGCTAAAGACATTGTTTGTTCTCAGAAAAA
TGGTGGAGTGTTGCTACAAGAGGAGGACGTTGCCGTTAGCAATGTTAGGATTGACTTGACACGTGGCAGAAATAATCCTCTTGAAAGGTTCAGTTTTGTTCAGGATTATG
AAAGCAACGATAAATTCAAGATTTCTGATGATCGCATAAGCCATTTACTGCCAACATCATATCAAGATATGATTGTAAGGGTGTATTCCAAGAAACCTGAACTGGTAGAA
GCCATTTCAGAAGCATTTGAAAACTTTCAGTTGAAAACTTATGGAATTAAAACACAAGTACATGCGACACCGGAGAAGAAGAAACGGCGCATTTGA

mRNA sequence

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Protein sequence

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MGASLIDELSLAPAYNFNSFQDLRCSKHVHDNVHGNIYLDPLSLKFIDTEQFQRLRELKQLGVTNMVYPGAVHSRFEHSLGVYWLAGEAVHKLKNYQGAELDIDHNDIQT
VKLAGLLHDVGHGPFSHLFEREFLPQVLSGYEWSHELMSVKMVDHIVDEHHIDIDSGMIKRVKEMILSSSEFTQPKGSREKGFLYDIVANGRNGIDVDKFDYIVRDCRAC
GLGCNFQFQRLLETMRVIDDEICYKAKDYLTIHKLFATRADLYRTVYMHPKVKAIELMIVDALVKANDYLEISSHIHDPSQYWKLDDSVVKTIETASDQELKESRDLILR
IRRRNLYQFCNEYAVPKEKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLERFSFVQDYESNDKFKISDDRISHLLPTSYQDMIVRVYSKKPELVE
AISEAFENFQLKTYGIKTQVHATPEKKKRRI

Lag0027691 (gene) of Sponge gourd (AG-4) v1 genome