CuGenDBv2

Gene ID	Lag0028484
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	GPI mannosyltransferase 1
Genome location	chr8:23297223..23297737
RNA-Seq Expression	Lag0028484
Synteny	Lag0028484
Gene Ontology terms	GO:0006506 - GPI anchor biosynthetic process (biological process) GO:0097502 - mannosylation (biological process) GO:0005789 - endoplasmic reticulum membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:1990529 - glycosylphosphatidylinositol-mannosyltransferase I complex (cellular component) GO:0004376 - glycolipid mannosyltransferase activity (molecular function) GO:0051751 - alpha-1,4-mannosyltransferase activity (molecular function)
InterPro domains	IPR007704 - GPI mannosyltransferase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6589029.1 GPI mannosyltransferase 1, partial [Cucurbita argyrosperma subsp. sororia]

3.1e-45

78.4

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SLL L AIFRL LI YGEWQDAHMEVRYTDVDYIVF++  SLMASGKSPYLRSTYRYSPLL +LLIPNSIFH  W   +FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL I SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

XP_022928135.1 GPI mannosyltransferase 1-like isoform X1 [Cucurbita moschata]

1.8e-45

76.8

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SL+ L AIFRL LI YGEWQDAHMEVRYTDVDYIVF++  SLMA+GKSPYLRSTYRYSPLL +LLIPNSIFH  W  F+FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL + SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

XP_022952483.1 GPI mannosyltransferase 1-like [Cucurbita moschata]

6.2e-46

78.4

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        M SF F SLL L AIFR VLI YGEWQDAHMEVRYTDVDYIVF++  SLMASGKSPYLRSTYRYSPLL +LLIPNSIFH  W  F+FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL I SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

XP_023554127.1 GPI mannosyltransferase 1-like [Cucurbita pepo subsp. pepo]

2.1e-46

79.2

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SLL L AIFR VLI YGEWQDAHMEVRYTDVDYIVF++  SLMASGKSPYLRSTYRYSPLL +LLIPNSIFH  W  F+FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL I SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

XP_038888807.1 GPI mannosyltransferase 1 [Benincasa hispida]

1.1e-45

77.6

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SLL L AIFR +LI YGEWQDAHMEVRYTDVDYIVF++  SLMASG+SPYLRSTYRYSPLL +LLIPNSIFH  W  F+FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL I SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

TrEMBL top hits

e value

%identity

Alignment

A0A5D3DIB1 GPI mannosyltransferase 1

7.4e-45

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SLL L AIFR VLI YGEWQDA+MEVRYTDVDYIVF++  SLMASGKSPY+RSTYRYSPLL +LLIPN+IFH  W  F+FSASDLLVG+FI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL I SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

A0A6J1C388 GPI mannosyltransferase 1

4.3e-45

77.6

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SLL L AIFRLVLI YGEWQDAHMEVRYTDVDYIVF++  SLMASGKSPYLRSTYRYSPLL +LLIPNSI H  W   +FSASDLLVG FI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL I SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

A0A6J1EQU0 GPI mannosyltransferase 1

8.7e-46

76.8

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SL+ L AIFRL LI YGEWQDAHMEVRYTDVDYIVF++  SLMA+GKSPYLRSTYRYSPLL +LLIPNSIFH  W  F+FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL + SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

A0A6J1GKC7 GPI mannosyltransferase 1

3.0e-46

78.4

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        M SF F SLL L AIFR VLI YGEWQDAHMEVRYTDVDYIVF++  SLMASGKSPYLRSTYRYSPLL +LLIPNSIFH  W  F+FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL I SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

A0A6J1JM87 GPI mannosyltransferase 1

1.9e-45

76.8

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Query:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN
        MASF F SLL L AIFRL LI YGEWQDAH+EVRYTDVDYIVF++  SLMASGKSPYLRSTYRYSPLL +LLIPNSIFH  W   +FSASDLLVGFFI  
Subjt:  MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISN

Query:  ILKKCGIPENLFISSVIVWLFNLVT
        ILKK G+PENL ++SV+VWLFN  T
Subjt:  ILKKCGIPENLFISSVIVWLFNLVT

SwissProt top hits

e value

%identity

Alignment

Q4I073 GPI mannosyltransferase 1

6.7e-19

41.23

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Query:  LLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKCGIP
        L  +  + RL L+ YG +QDAH  ++YTD+DY+VFT+    +A G+SPY R TYRY+PLL ++L+P   F  +    +F+A+DLL G+ I  +L++ G+ 
Subjt:  LLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKCGIP

Query:  ENLFISSVIVWLFN
        E        +WL+N
Subjt:  ENLFISSVIVWLFN

Q4R4E1 GPI mannosyltransferase 1

1.9e-18

42.45

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Query:  RLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKCGIPENLFISSV
        R+ L+ YG +QD  + VRYTD+DY VFT+    +A G+SPYLR+TYRY+PLL +LL PN      +  F+F + DLL  F +  +L   G+         
Subjt:  RLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKCGIPENLFISSV

Query:  IVWLFN
        + WL N
Subjt:  IVWLFN

Q500W7 GPI mannosyltransferase 1

3.8e-38

65.83

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Query:  FNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKC
        F SLL    + R+ LI YGEWQDAHMEVRYTDVDYIVF++  SLMASG+SPY R+TYRYSPLL  LL PNS FH  W  F+FSASDLLVG+FI  ILK+ 
Subjt:  FNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKC

Query:  GIPENLFISSVIVWLFNLVT
         +PE +   SV+VWLFN  T
Subjt:  GIPENLFISSVIVWLFNLVT

Q54IA4 GPI mannosyltransferase 1

1.0e-19

41.82

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Query:  IFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNIL--KKCGIPENLF
        + RLVLI + EWQDA+M V+YTD+DY+V+T+    + +G SPY RSTYRY+PLL YLL+PN + H  +   +F   D+++ + +  IL  +   I     
Subjt:  IFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNIL--KKCGIPENLF

Query:  ISSVIVWLFN
        +  +  WL N
Subjt:  ISSVIVWLFN

Q75C82 GPI mannosyltransferase 1

7.9e-20

43.9

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Query:  CFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHH-YWANFMFSASDLLVGFFISNILK
        C   L  LLA  R+    YG +QDAH  V+YTD+DY VF +    +A G SPYLR TYRY+PLL ++L+PN      ++  F+F   DLL G  + N+L 
Subjt:  CFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHH-YWANFMFSASDLLVGFFISNILK

Query:  KCGIPENLFISSVIVWLFNLVTL
        KCG    L ++S  +WL N V +
Subjt:  KCGIPENLFISSVIVWLFNLVTL

Arabidopsis top hits

e value

%identity

Alignment

AT5G22130.1 mannosyltransferase family protein

2.7e-39

65.83

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Query:  FNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKC
        F SLL    + R+ LI YGEWQDAHMEVRYTDVDYIVF++  SLMASG+SPY R+TYRYSPLL  LL PNS FH  W  F+FSASDLLVG+FI  ILK+ 
Subjt:  FNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKC

Query:  GIPENLFISSVIVWLFNLVT
         +PE +   SV+VWLFN  T
Subjt:  GIPENLFISSVIVWLFNLVT

AT5G22130.2 mannosyltransferase family protein

1.1e-35

56.43

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Query:  FNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSA----------------
        F SLL    + R+ LI YGEWQDAHMEVRYTDVDYIVF++  SLMASG+SPY R+TYRYSPLL  LL PNS FH  W  F+FSA                
Subjt:  FNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSA----------------

Query:  ----SDLLVGFFISNILKKCGIPENLFISSVIVWLFNLVT
            SDLLVG+FI  ILK+  +PE +   SV+VWLFN  T
Subjt:  ----SDLLVGFFISNILKKCGIPENLFISSVIVWLFNLVT

Sequences

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CDS sequence

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ATGGCATCCTTTTGCTTCAACTCCCTGCTAAATCTCTTAGCGATCTTCAGGTTGGTACTTATTCCCTACGGTGAGTGGCAAGATGCGCACATGGAGGTCAGGTACACTGA
TGTCGATTACATTGTTTTCACGAACACTGTTTCTCTAATGGCGTCTGGAAAGTCTCCCTATCTGAGATCCACTTATAGATACTCACCATTGCTCGTGTACTTGCTCATTC
CGAACTCTATCTTCCATCACTATTGGGCCAATTTTATGTTCTCAGCGTCAGATTTGCTCGTCGGGTTCTTTATAAGTAATATTTTGAAAAAATGTGGCATTCCAGAAAAT
TTGTTCATCAGTTCTGTTATTGTTTGGCTTTTCAACCTCGTTACTTTATATTGGCACCGGAGGAAACTGCGAACCTCTTGTTTGTGCGATGGTTCTTAA

mRNA sequence

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Protein sequence

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MASFCFNSLLNLLAIFRLVLIPYGEWQDAHMEVRYTDVDYIVFTNTVSLMASGKSPYLRSTYRYSPLLVYLLIPNSIFHHYWANFMFSASDLLVGFFISNILKKCGIPEN
LFISSVIVWLFNLVTLYWHRRKLRTSCLCDGS

Lag0028484 (gene) of Sponge gourd (AG-4) v1 genome