CuGenDBv2

Gene ID	Lag0031143
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	DNA topoisomerase 2
Genome location	chr11:5264538..5271318
RNA-Seq Expression	Lag0031143
Synteny	Lag0031143
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0e+00

92.22

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        PIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG ACEL+P+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR
        T+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQR+K NND+KP+
Subjt:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR

Query:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSA
        ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTTTEVA+N VVKPKGK AAPRKAPAKK GKAAV+   D+DDDDEVLELKDRLAAYK+ESSP+ SEVSA
Subjt:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSA

Query:  METEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSG
        METEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ SD+ D D DFEIKEIAPPAAKKGGGRKAAA AKTTK     KK+EP A+LGQKLITQMLEP ENSG
Subjt:  METEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSG

Query:  ISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDAD
        ISPEKKVRKIR SPFNKKSGS+LGR   E  EEEE EE GN+GK+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+
Subjt:  ISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDAD

Query:  FDED
         DED
Subjt:  FDED

XP_022152631.1 DNA topoisomerase 2 isoform X1 [Momordica charantia]

0.0e+00

92.21

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        P+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG  CEL+PEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI
        T+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQR+KANNDVKP+I
Subjt:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI

Query:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME
        SRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AAPRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSEVSAME
Subjt:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME

Query:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI
        TEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDNDDS DDDFEIKE+APPAAKKGGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GI
Subjt:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD
        SPEKKVRK+RASPFNKKSGSILGRVG  E EEEE EE GN+GKIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD
Subjt:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD

Query:  ED
        ++
Subjt:  ED

XP_022152632.1 DNA topoisomerase 2 isoform X2 [Momordica charantia]

0.0e+00

92.08

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        P+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG  CEL+PEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI
        T+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQR+KANNDVKP+I
Subjt:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI

Query:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME
        SRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AAPRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSE  AME
Subjt:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME

Query:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI
        TEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDNDDS DDDFEIKE+APPAAKKGGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GI
Subjt:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD
        SPEKKVRK+RASPFNKKSGSILGRVG  E EEEE EE GN+GKIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD
Subjt:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD

Query:  ED
        ++
Subjt:  ED

XP_022935016.1 DNA topoisomerase 2 isoform X2 [Cucurbita moschata]

0.0e+00

92.22

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        PIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG ACEL+P+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR
        T+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQR+K NND+KP+
Subjt:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR

Query:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTTTEVA+N VVKPKGK AAPRKAPAKKGK AV+   D+DDDDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI
        ETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ SD+ D D DFEIKEIAPPAAKKGGGRKAAA AKTTK     KK+EP A+LGQKLITQMLEP ENSGI
Subjt:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADF
        SPEKKVRKIR SPFNKKSGS+LGR   E  EEEE EE GN+GK+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+ 
Subjt:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADF

Query:  DED
        DED
Subjt:  DED

XP_023527823.1 DNA topoisomerase 2 isoform X3 [Cucurbita pepo subsp. pepo]

0.0e+00

92.15

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        PIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG ACEL+P+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR
        T+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQR+K NNDVKP+
Subjt:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR

Query:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTTTEVA+N VVKPKGK AAPRKAPAKKGKAAV+   D+DDDDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI
        ETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ SD+ D + DFEIKEIAPPAAKKGGGRKAAA AKTTK     KK+EP A+LGQKLITQMLEP ENSGI
Subjt:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGR-VGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAP-ARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDAD
        SPEKKVRKIR SPFNKKSGS+LGR +G    EEEEE E GN+GK+MGSASSETT+E  G  P ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +AD
Subjt:  SPEKKVRKIRASPFNKKSGSILGR-VGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAP-ARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDAD

Query:  FDED
         DED
Subjt:  FDED

TrEMBL top hits

e value

%identity

Alignment

A0A6J1DGT3 DNA topoisomerase 2

0.0e+00

92.08

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        P+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG  CEL+PEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI
        T+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQR+KANNDVKP+I
Subjt:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI

Query:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME
        SRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AAPRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSE  AME
Subjt:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME

Query:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI
        TEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDNDDS DDDFEIKE+APPAAKKGGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GI
Subjt:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD
        SPEKKVRK+RASPFNKKSGSILGRVG  E EEEE EE GN+GKIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD
Subjt:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD

Query:  ED
        ++
Subjt:  ED

A0A6J1DIB5 DNA topoisomerase 2

0.0e+00

92.21

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        P+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG  CEL+PEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI
        T+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQR+KANNDVKP+I
Subjt:  TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRI

Query:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME
        SRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AAPRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSEVSAME
Subjt:  SRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAME

Query:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI
        TEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDNDDS DDDFEIKE+APPAAKKGGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GI
Subjt:  TEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDNDDS-DDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD
        SPEKKVRK+RASPFNKKSGSILGRVG  E EEEE EE GN+GKIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD
Subjt:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFD

Query:  ED
        ++
Subjt:  ED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

92.22

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        PIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG ACEL+P+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR
        T+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQR+K NND+KP+
Subjt:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR

Query:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTTTEVA+N VVKPKGK AAPRKAPAKKGK AV+   D+DDDDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI
        ETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ SD+ D D DFEIKEIAPPAAKKGGGRKAAA AKTTK     KK+EP A+LGQKLITQMLEP ENSGI
Subjt:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADF
        SPEKKVRKIR SPFNKKSGS+LGR   E  EEEE EE GN+GK+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+ 
Subjt:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADF

Query:  DED
        DED
Subjt:  DED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

92.15

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        PIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG ACEL+P+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR
        T+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQR+K NND+KP+
Subjt:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR

Query:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSA
        ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTTTEVA+N VVKPKGK AAPRKAPAKK GK AV+   D+DDDDEVLELKDRLAAYK+ESSP+ SEVSA
Subjt:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSA

Query:  METEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSG
        METEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ SD+ D D DFEIKEIAPPAAKKGGGRKAAA AKTTK     KK+EP A+LGQKLITQMLEP ENSG
Subjt:  METEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSG

Query:  ISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDAD
        ISPEKKVRKIR SPFNKKSGS+LGR   E  EEEE EE GN+GK+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+
Subjt:  ISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDAD

Query:  FDED
         DED
Subjt:  FDED

A0A6J1J555 DNA topoisomerase 2

0.0e+00

92.15

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVE KRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        S+KVVID EQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV
        PIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQ+SFG ACEL+P+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI 
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM

Query:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRR+LDGE M+PMDPWYRGFSGTIEKTATKEGGTSYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVS

Query:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL
        GIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSI+VHLTEENMILAMQEGLKKKFK+T T+STSNMHL
Subjt:  GIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR
        T+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQR+K NND+KP+
Subjt:  TEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPR

Query:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSE +TESMD  TSSSTTTEVA+N VVKPKGK AAPRKAPAKKGKAAV+   D+D DDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI
        ETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ SD+ D D DFEIKEIAPPAAKKGGGRKAAA AKTTK     KK+EP A+LGQKLITQMLEP ENSGI
Subjt:  ETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAA-AKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADF
        SPEKKVRKIR SPFNKKSGS+LGR   E  EEEE EE GN+GK+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +AD 
Subjt:  SPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADF

Query:  DED
        DED
Subjt:  DED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

63.68

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Query:  KKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SNAAN+      P KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHR+V+YVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  VIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPIIT
         ID E N +SV+NNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVFS+NMG K EP+IT
Subjt:  VIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPIIT

Query:  KCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSE
        KCK S+NWTKVTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  KSF+DY DL+LK A      P  R H K  +RWEI ++LS+
Subjt:  KCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSE

Query:  GQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNVATKS
        GQFQQVSFVN IATIKGGTHVDYITNQI  Y+M  VNKK K+ANVKAH VK++LWVF+N+LIDNPAFDSQTKETLT RQ SFG  C++    LK+V  KS
Subjt:  GQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNVATKS

Query:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKE
        GI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQIM+N+E
Subjt:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKE

Query:  IQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNAS
        IQ IK+ILGLQQ KEY+N K+LRYGHLMIM DQDHDGSHIKGLLINFIHSFWP+LL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+
Subjt:  IQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNAS

Query:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSM
         W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKKK E RK W+R FEPGT  D   KLI Y DFVNKELILFS AD        
Subjt:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSM

Query:  VDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF
                   L+ SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF
Subjt:  VDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF

Query:  PKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIE
         + DDKLL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSYIPNYNPR+II NVRRLL+GE +VPMDPWY+GF GTIEK+A KEGG  Y V+G + 
Subjt:  PKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIE

Query:  EVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHLFDAN
        E+ + T RI ELP+RKWT DYK+FL+S+T        D     KDP IE    + DD IV I++ +  E +   +QEGL KKFK+T+TISTSNMHLFDA 
Subjt:  EVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNMHLFDAN

Query:  GVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEET
        G  KK+DTPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL VVNGEIIVSNR++ +L  EL+ KGFTP P+K KS +P+VAGA+++  E 
Subjt:  GVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEET

Query:  EESPE---------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANND
        +E  E         V+G    DY+ LL+L IGTLT+E VQ+L +++ + + E E L      SLWLKDLD  EK+LDE+D   A+ +  R  Q  K  N 
Subjt:  EESPE---------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANND

Query:  VKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEV
           + ++  P+  +N+KK        +S++  + +++ E+  NAV     +AA P +    KG+AA   +  ++ +D++  L++RLAAY IESS ++S+ 
Subjt:  VKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEV

Query:  SAMETEVPQVQPAKKKEPSKRAPAKKK-TTAKSAQNSDN-----DDSDDDF-EIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA----------K
         AME+E  Q + A KK+ +KR  AKKK +T     +SDN     DD DDDF E+++ A P  K  GGRK AA    K PA A  + PAA           
Subjt:  SAMETEVPQVQPAKKKEPSKRAPAKKK-TTAKSAQNSDN-----DDSDDDF-EIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAA----------K

Query:  LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSE
         GQKL+T ML+PAE +G SPEKKVRK+R SPFNKKSGSILGR      ++       + G    +  SE         PAR R QRA RTQ++Y +S+SE
Subjt:  LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSE

Query:  SEPASEDSDFDEKDADFDED
        SE   EDSD D + +DF+ED
Subjt:  SEPASEDSDFDEKDADFDED

O46374 DNA topoisomerase 2-alpha

0.0e+00

45.49

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKK--TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDP
        M V   +P+  +   N  +     KK  +IE +YQKKTQLEHILLRPDTY+GS+E  TQ +WVY+ D  + +R VT+VPGLYKIFDEILVNAADNKQRDP
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKK--TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDP

Query:  SMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGK
         M  ++V ID E N IS++NNG G+PV  H+ EK+YVP LIFG LLTSSNYDD  KK TGGRNGYGAKL NIFST+F +ETA  +  K +KQ + DNMG+
Subjt:  SMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGK

Query:  KSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWE
          E +  K    +++T +TF PDL+KF M  L+ D+VALM +R  D+AG   K VKV LNG ++PVK F+ YVDLYLK     +  P K  H + N RWE
Subjt:  KSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWE

Query:  IVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEF
        + +T+SE  FQQ+SFVN IAT KGG HVDY+ +QI   ++ VV KKNK    VKAH VK+++W+F+NALI+NP FDSQTKE +T++  SFG  C+LS +F
Subjt:  IVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEF

Query:  LKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS
        +K  A   GI++S+L+WV FK    L KK    K  +I GI KL+DAN AGG+NS +CTLILTEGDSAK LA++GLGVVGRD YGVFPLRGK+LNVREAS
Subjt:  LKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS

Query:  SKQIMENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEY
         KQIMEN EI  I +I+GLQ  K Y    + K LRYG +MIMTDQD DGSHIKGLLINFIH  WP+LLR   FL EFITPIVK + +N   ++FY++PE+
Subjt:  SKQIMENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEY

Query:  ESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFE-----------PGTHL-DQTEKLIK
        E WK S   N   W +KYYKGLGTSTSKE +EYF  + +H+  F +    D  AI LAFSKK+I++RK WL  F            P  +L  QT   + 
Subjt:  ESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFE-----------PGTHL-DQTEKLIK

Query:  YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRN
        Y+DF+NKELILFS +D +RSIPSMVDGLKPGQRK+L+  FKRN  +E KV+Q +G V+E S+YHHGE SL  TII +AQ+FVGSNN+NLL P GQFGTR 
Subjt:  YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRN

Query:  HGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRG
        HGGKD AS RYI+T LS + R LFP  DD  L +L +D Q +EP WY+PIIP VL+NG+EGIGTGWS  IPN++ R+++ N+R L+DGE  +PM P Y+ 
Subjt:  HGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRG

Query:  FSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQ
        F GTIE+ A  +    Y +SG +  ++ TT+ I ELP+R WT  YKE      +V        EK    P I     +  D  V   V +TEE +  A +
Subjt:  FSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQ

Query:  EGLKKKFKVTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGF
         GL K FK+  +++ ++M LFD  G +KKYDT   IL +FF LRL++Y  RK  LL  L  E  KL N+ RFIL  ++G+II+ N+ + +L   L  +G+
Subjt:  EGLKKKFKVTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGF

Query:  TPFPKKT-KSVEPEVAGASNETEETEESPEVKGERVSD----YEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMD
           P K  K  + +V       E   E    K + V+D    + YLL + +  LT EK  ELC  R++ + E+E L++ +P  LW +DL +  +EL+ ++
Subjt:  TPFPKKT-KSVEPEVAGASNETEETEESPEVKGERVSD----YEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMD

Query:  RNDAQAEE--------------------------------VRKQQRVKANNDVKPRI-SRNAPKAP------------RNSKKTSNSEAVTESMDTT---
          + Q E+                                V  + + +A   +K +I S N   +P            R  KK            TT   
Subjt:  RNDAQAEE--------------------------------VRKQQRVKANNDVKPRI-SRNAPKAP------------RNSKKTSNSEAVTESMDTT---

Query:  --------------SSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDED--DDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQVQPAKKK
                      S S  +   SN  V P+ K   PR+A AK  K  V  D DED  D DE    +D + +   ++SP ++E S   T        K+ 
Subjt:  --------------SSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDED--DDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQVQPAKKK

Query:  EPSKRAPAKKKTTAKSAQN----SDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRA
        +P K  P+     A  A++    S +    D   + E   P +KK    K  AAK+    +    ++ AA  G K    +          P+ K R+ R 
Subjt:  EPSKRAPAKKKTTAKSAQN----SDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRA

Query:  SPFNKKSGSILGRVGIEEVEEEEEEEGGND
           +  S S   ++ I +    ++ +G +D
Subjt:  SPFNKKSGSILGRVGIEEVEEEEEEEGGND

P08096 DNA topoisomerase 2

0.0e+00

48.48

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Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS
        M   ++ PL  +N      + T         YQ+ T  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++VTYVPGLYKIFDEI+VNAADNK RDP+
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKK
        M+++KV +D E N IS++NNG G+P+E+H +EK+Y+PELIFG+LLTSSNYDD  KK TGGRNGYGAKL NIFSTEFV+ETAD +R+KKYKQ + DNM +K
Subjt:  MDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKK

Query:  SEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEI
        SEP+IT  K+ D +TK+TFKPDLAKF M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ +  F+ YV++YL S +    EPP+  +   N+RW++
Subjt:  SEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLK
           +S+GQF+QVSFVN I+TI+GGTHV+Y+ N+I + +  VV K+NK A VKA  +K+Y+ VF+N  I+NP+FDSQTKETLT + ++FG  C LS +FLK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLK

Query:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +  KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  Q
Subjt:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  IMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKES
        I+ NKEIQ IK+I+G    K Y++ K LRYGHLMIMTDQDHDGSHIKGL+IN++ S +P+LL++P FL++FITPI+K T R   V +FYT+PEYE WKE+
Subjt:  IMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQ
           N  GW IKYYKGLGTS   + + YF  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T+  I   DF+N+ELI FSMAD  
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQ

Query:  RSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSN
        RSIPS+VDGLKPGQRK++Y  FKRN + E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLLMPNGQFGTR+ GGK+ ++SRY+ T LS 
Subjt:  RSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSN

Query:  VTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYT
        + R LF  +DD+LLNY N++GQ IEP +Y+PI+P VLVNG+EGIGTGWS++IPNYNP+DI  N+R +L+GE +  M PWYRGF G+I K A       Y 
Subjt:  VTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYT

Query:  VSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNM
        +SGII ++ +  + I ELP+R WT D KE+L++            EK  K  FI   + H  +  V  +V LTE  M  A+ E L+ KFK++ T +TSNM
Subjt:  VSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSNM

Query:  HLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAG
          FDA+G IKKYD+ E IL EF+ +RL  Y++RK +++  LE    +  N+ RFI  ++ GE++VS +++ DL  EL+ K F P   PKK   V+ EV  
Subjt:  HLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAG

Query:  ASNETEETEESPEVKGERVSD-YEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLE----KELDEMDRNDAQAEEVRKQQRVK
          N   E E+S +V  +  SD Y YLL++ + +LT E+  EL   +D++  E++ L K TPK LWL DLD+ E    K +D++ R     EE +  +   
Subjt:  ASNETEETEESPEVKGERVSD-YEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLE----KELDEMDRNDAQAEEVRKQQRVK

Query:  ANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPD
             KPR      + PR    +S+S AV +   + S  +TT      +++      A  K P K     +V  +D      V E  +R++      S D
Subjt:  ANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPD

Query:  RSEVSAMETEVPQVQPAKKKEPSKRAPAK-----KKTTAKSAQNSDNDDSDDDFEIKEIAP------PAAKKGGGRKAAAAKTTKP
         S  S   ++    + A  K+P K+  A      +KT    A    + D +DD     + P       A+ K  G+KA++ K   P
Subjt:  RSEVSAMETEVPQVQPAKKKEPSKRAPAK-----KKTTAKSAQNSDNDDSDDDFEIKEIAP------PAAKKGGGRKAAAAKTTKP

P30182 DNA topoisomerase 2

0.0e+00

63.54

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Query:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + P   +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIV
        P+ITKC +S+NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+   TE P  R   K N+RWE+ 
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQ+SFG  CELS +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  MENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE
          NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWP+LL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKE
Subjt:  MENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKIL+ +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLL+PNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS++IPNYNPR+I+ NVRRLL+GE+MVPMDPWYRGF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSY

Query:  TVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSN
        T++G+ EEV +TT+RI ELP+R+W +DYK FL S+     K D         PF +    ++D+K V  D+ L+EENM+ A QEG  KKFK+T TI+TSN
Subjt:  TVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AG 
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-

Query:  ----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQ
            A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL+SL+KEL+++D  DAQ ++     Q+
Subjt:  ----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQ

Query:  RVKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIE
        +++A +    ++ R APK P   KKT+   + +E+ + + S+  T+     VVKPK +  A +KA   +   A  +  D D++  EV++ K R  A K  
Subjt:  RVKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIE

Query:  SSPDRSEVSAMETEVPQVQPAKKKEPSKR---APAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLI
            ++  +A E E  ++    ++        APA    TA++++    DD DDD  + E+AP    K GGRK AA K  KPPAA +KR        +++
Subjt:  SSPDRSEVSAMETEVPQVQPAKKKEPSKR---APAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLI

Query:  TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASE
                  G+SPEKKVRK+R+SPFNKKS S++ R+   + EE  E   GN           ++E++ G   A  R QRA R ++ YV+SDSESE A+ 
Subjt:  TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASE

Query:  DSDFDEKDADFDED
        DS+FD+ + D D++
Subjt:  DSDFDEKDADFDED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

47.92

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Query:  KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE
        K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR V++VPG+YKIFDEILVNAADNKQR+ +M  +KVVID E+  ISV N+G G+P++
Subjt:  KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE

Query:  VHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFN
        VH E K+Y+PELIFG+LLTSS+YDD+ K+ TGGRNG+GAKL NIFST+F++E AD K  K YKQ F++NM  K +P IT  +   ++TK+TF P+L +F 
Subjt:  VHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFN

Query:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGIATIKGGTH
        M   +DD+VAL+ KRV D+AGC   T+KV LN + + ++SF+ Y++LY           PK Y+ K ++RWE+ VTLS E QF QVSFVN I T+KGGTH
Subjt:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGIATIKGGTH

Query:  VDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNVA-TKSGIMDSVLSWVNFKQSKDL
        V +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDSQTKETLT + +SFG  CE S +F+K V  +KSGI+ S+L +  FK    L
Subjt:  VDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNVA-TKSGIMDSVLSWVNFKQSKDL

Query:  KK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEY
        K+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K ++ N EI  I  ILGL+ GK Y
Subjt:  KK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEY

Query:  SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSK
             LRYGHLMIMTDQDHDGSHIKGL+IN +H FWPTLLR+P FLVEFITPIVK    N   +SFYTMPE+  W+E+   N  GW +KYYKGLGTST  
Subjt:  SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSK

Query:  EGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQ-TEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCS
        EG+EYF  L +HK DF W D+   + IELAFSK + ++RK W+ +   GT L+Q   K + YSDF+NKEL+LFS+AD +RSIP++VDGLK   RK LY  
Subjt:  EGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQ-TEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCS

Query:  FKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDG
        FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMAQ+FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+++ R ++  DDD +L+ + +DG
Subjt:  FKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDG

Query:  QSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIE-KTATKEGGTSYTVSGIIEEVSDTTLRIIELPV
        + ++P +Y+P+IP +LVNG  GIGTGWSS IPNYNPRD+I+N+R  +DG+ + P+ PWYRGF G+IE    +K  G  Y   GI +++SD    I ELP+
Subjt:  QSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIE-KTATKEGGTSYTVSGIIEEVSDTTLRIIELPV

Query:  RKWTNDYKEFLDSV----TRVAAKNDKDKEKA------AKDPFIEQADHHSDD----KIVSIDV------------HLTEENMILAMQEGLKKKFKVTNT
          WT DY+E LD +    TR   K +K+K+ A      AK    +++    DD    K+    V            H   + +    +  ++K FK+ +T
Subjt:  RKWTNDYKEFLDSV----TRVAAKNDKDKEKA------AKDPFIEQADHHSDD----KIVSIDV------------HLTEENMILAMQEGLKKKFKVTNT

Query:  ISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF---------
        I+ +NM +FD  G I+++ T   + E FFPLR++ Y+ RK  L E L  E  +L NK RFILAVVN E+++SN ++VDL ++L+   F            
Subjt:  ISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF---------

Query:  ---PKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDA-
            KK K+   E   A +  EE + + E + +    Y+YLL+L + +LT+E+V++L  +RD  K E + L     + ++ +DLD+LEK LD+ D  D  
Subjt:  ---PKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDA-

Query:  ---QAEEVRKQQRVKANNDVKP------RISRNAP---------KAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRK-APAKKGKA
           Q E ++K+ + KA    K       + ++ AP         K P  +    +     +S DTTS+ST+T  +SN        A   +K  PA K   
Subjt:  ---QAEEVRKQQRVKANNDVKP------RISRNAP---------KAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRK-APAKKGKA

Query:  AVVNDDDED-DDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQVQPAKKKEPSKR--APAKKKTT--AKSAQNSD----NDDSDDDFEIK
         V  D D D DDD V+  K +    K     + S+ S  E++    Q +  + P KR  AP KK TT   K A  S     +D S DD  IK
Subjt:  AVVNDDDED-DDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQVQPAKKKEPSKR--APAKKKTT--AKSAQNSD----NDDSDDDFEIK

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

4.4e-23

23.93

Show/hide

Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNY--DDTVKKTTGGRNGYGAKLTNIFSTEF
        GL+ +  EIL NA D  Q       + VV+  + + +S+ +NG G+P ++H        E +   L     +    +    +GG +G G  + N  S   
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNY--DDTVKKTTGGRNGYGAKLTNIFSTEF

Query:  -VIETADGKRLKKYKQVFSDNMGKKSEPIIT-KC------KESDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKS
         VI   DG    +++Q +S     + +P+ T  C            T + F PD   F      + + +A   + +  L   +  ++K E +     V S
Subjt:  -VIETADGKRLKKYKQVFSDNMGKKSEPIIT-KC------KESDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKS

Query:  FQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMTVVNK--------------
           Y     +  S  +T+  K  H     R EI  +  +   Q          + + N I TI GGTH++ +   +   + ++  K              
Subjt:  FQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMTVVNK--------------

Query:  ----------------------KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QNSFGCACELSPEFLKNVATKSGIMDSV
                                K+ ++   +V+  L   ++  + NP F+ QTK  L    +R       Q       EL P+ L+++ +KS  +++ 
Subjt:  ----------------------KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QNSFGCACELSPEFLKNVATKSGIMDSV

Query:  LSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIK
         + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EIQ + 
Subjt:  LSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIK

Query:  QILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIK
          LGL    E  N + LRY  ++I+TD D DG+HI+ LL+ F   +   L       V  + P+ K   R       Y     +    S  GNAS ++I+
Subjt:  QILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIK

Query:  YYKGLG
         +KGLG
Subjt:  YYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

63.54

Show/hide

Query:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + P   +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIV
        P+ITKC +S+NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+   TE P  R   K N+RWE+ 
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQ+SFG  CELS +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  MENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE
          NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWP+LL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKE
Subjt:  MENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKIL+ +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLL+PNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS++IPNYNPR+I+ NVRRLL+GE+MVPMDPWYRGF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSY

Query:  TVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSN
        T++G+ EEV +TT+RI ELP+R+W +DYK FL S+     K D         PF +    ++D+K V  D+ L+EENM+ A QEG  KKFK+T TI+TSN
Subjt:  TVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AG 
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-

Query:  ----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQ
            A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL+SL+KEL+++D  DAQ ++     Q+
Subjt:  ----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQ

Query:  RVKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIE
        +++A +    ++ R APK P   KKT+   + +E+ + + S+  T+     VVKPK +  A +KA   +   A  +  D D++  EV++ K R  A K  
Subjt:  RVKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIE

Query:  SSPDRSEVSAMETEVPQVQPAKKKEPSKR---APAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLI
            ++  +A E E  ++    ++        APA    TA++++    DD DDD  + E+AP    K GGRK AA K  KPPAA +KR        +++
Subjt:  SSPDRSEVSAMETEVPQVQPAKKKEPSKR---APAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLI

Query:  TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASE
                  G+SPEKKVRK+R+SPFNKKS S++ R+   + EE  E   GN           ++E++ G   A  R QRA R ++ YV+SDSESE A+ 
Subjt:  TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASE

Query:  DSDFDEKDADFDED
        DS+FD+ + D D++
Subjt:  DSDFDEKDADFDED

AT3G23890.2 topoisomerase II

0.0e+00

63.77

Show/hide

Query:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + P   +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSE

Query:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIV
        P+ITKC +S+NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+   TE P  R   K N+RWE+ 
Subjt:  PIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQ+SFG  CELS +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  MENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE
          NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWP+LL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKE
Subjt:  MENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKIL+ +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLL+PNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS++IPNYNPR+I+ NVRRLL+GE+MVPMDPWYRGF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSY

Query:  TVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSN
        T++G+ EEV +TT+RI ELP+R+W +DYK FL S+     K D         PF +    ++D+K V  D+ L+EENM+ A QEG  KKFK+T TI+TSN
Subjt:  TVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVTNTISTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AG 
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-

Query:  ----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQ
            A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL+SL+KEL+++D  DAQ ++     Q+
Subjt:  ----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQ

Query:  RVKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIES
        +++A +    ++ R APK P   KKT+   + +E+ + + S+  T+     VVKPKG+  A +KAPA            E ++DE+L+L  RLA Y   S
Subjt:  RVKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIES

Query:  SPDRSEVSAMETEVPQVQPAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQML
                                    APA    TA++++    DD DDD  + E+AP    K GGRK AA K  KPPAA +KR        +++    
Subjt:  SPDRSEVSAMETEVPQVQPAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQML

Query:  EPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDF
              G+SPEKKVRK+R+SPFNKKS S++ R+   + EE  E   GN           ++E++ G   A  R QRA R ++ YV+SDSESE A+ DS+F
Subjt:  EPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDF

Query:  DEKDADFDED
        D+ + D D++
Subjt:  DEKDADFDED

AT5G04130.1 DNA GYRASE B2

2.0e-28

24.53

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Query:  AANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCI
        +    Q  T  K    E  Q    L+ +  RP  Y+GS                     T   GL+ +  EIL NA D  Q   +   V VV+  +   +
Subjt:  AANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCI

Query:  SVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPIIT-KCK---
        SV +NG G+P ++H   K    E +   L     +  T      +GG +G G  + N  S    +E +  +   ++KQ +S     + +PI T  C+   
Subjt:  SVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPIIT-KCK---

Query:  ---ESDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLS
           +    T + F PD   F      + + +A   + +  L   +  ++K E +       S   +     +  S  +T+     H     R EI     
Subjt:  ---ESDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLS

Query:  EGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-----
        +   Q          + + N I TI GGTH++ +   +   + T+  K    K K+ ++   +V+  L   ++  + NP F+ QTK  L    +R     
Subjt:  EGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-----

Query:  --QNSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFY
          Q       EL P+ L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     R F 
Subjt:  --QNSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFY

Query:  GVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHR
         + PLRGK+LN+       + +N+EIQ +   LGL    E    + LRY  ++I+TD D DG+HI+ LL+ F   +   L       V  + P+ K   R
Subjt:  GVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHR

Query:  NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG
               Y   + +    +   NAS ++I+ +KGLG
Subjt:  NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG

Sequences

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CDS sequence

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ATGGCCGTGGAGAAGAAACGCCCACTGCAGAACAGCAACGCCGCCAATGTCGACCAGATTCCGACCGGCCCGAAGAAAACGATTGAAGAAATGTACCAGAAGAAGACTCA
GCTCGAGCACATTCTCCTCAGGCCCGATACTTATGTTGGATCGATCGAAAAGCACACCCAAAACCTCTGGGTTTACGAGAACGACAAGATGGTGCACCGATCCGTCACCT
ACGTGCCGGGTCTCTACAAGATCTTTGATGAAATTTTGGTCAATGCTGCAGATAATAAGCAGCGAGACCCCTCGATGGACTCTGTCAAGGTTGTGATTGATGTCGAGCAG
AACTGTATCAGTGTGTTCAACAATGGAGATGGAGTTCCGGTTGAGGTTCATCAAGAAGAGAAGGTTTATGTCCCTGAGTTGATCTTTGGACACTTGTTGACTAGTAGTAA
TTATGATGACACTGTGAAGAAAACCACCGGTGGACGAAATGGCTACGGTGCGAAACTTACGAATATTTTTTCCACTGAATTTGTGATCGAGACGGCTGATGGAAAACGCC
TGAAGAAGTATAAGCAGGTGTTCTCTGATAACATGGGGAAGAAATCTGAGCCGATCATAACAAAGTGCAAGGAGAGTGATAATTGGACCAAGGTGACTTTTAAGCCAGAC
TTGGCAAAGTTTAACATGACTCATCTTGAAGATGATGTTGTTGCACTGATGAAAAAGAGAGTGTTGGATTTGGCTGGATGCCTTGGAAAAACCGTGAAGGTTGAGTTGAA
TGGACAAAGAGTGCCTGTGAAATCGTTTCAAGATTATGTAGATCTCTATCTCAAATCGGCTTCTGCATTCTCGACAGAACCTCCAAAACGGTATCACATTAAGCCTAATG
AGAGATGGGAAATCGTGGTGACCTTAAGTGAGGGGCAGTTCCAACAGGTCAGCTTTGTGAATGGGATTGCAACTATTAAGGGTGGGACTCATGTTGATTACATCACTAAT
CAAATAGCAAATTATGTGATGACGGTTGTAAATAAGAAGAACAAAAATGCTAATGTGAAGGCCCACAACGTGAAGAGCTATTTGTGGGTTTTTATCAACGCTCTCATTGA
TAATCCTGCCTTCGATTCCCAAACCAAGGAAACTTTGACAATTCGTCAAAACAGTTTTGGTTGTGCATGCGAACTTTCACCAGAGTTTTTGAAGAATGTGGCCACAAAAT
CTGGAATTATGGACAGCGTTCTCTCGTGGGTTAATTTCAAGCAAAGCAAAGACCTGAAAAAAACTGATGGAGCAAAAACAGAAAAGATTAGTGGTATCGAAAAGTTGGAG
GATGCCAATTGTGCTGGAGGGAAAAACTCAGAAAAATGTACTTTGATTTTGACAGAAGGAGATTCAGCCAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTGGGACGAGA
CTTCTATGGCGTATTCCCACTAAGAGGTAAATTGCTCAATGTGAGGGAAGCGAGTAGCAAACAAATCATGGAGAATAAAGAAATCCAGTACATCAAGCAAATTCTTGGAC
TTCAGCAAGGGAAGGAATACAGCAATGCTAAGGCTTTGAGATATGGTCATTTGATGATTATGACCGATCAGGATCATGATGGTTCGCACATTAAAGGGCTCTTGATCAAC
TTTATTCATTCTTTCTGGCCTACTCTCCTAAGAGTTCCGTCTTTCTTGGTTGAGTTCATTACGCCTATTGTCAAGGCTACTCATAGAAATGGAACTGTTTTGTCATTCTA
CACCATGCCTGAGTATGAGTCTTGGAAAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCGAAAGAAGGAAGAG
AGTACTTTGAACAGCTGACGAAGCATAAGAAAGATTTTATTTGGCAAGATGACCATGATGGAGAGGCCATTGAACTTGCCTTCAGTAAGAAGAAGATTGAAGAGAGGAAG
AATTGGCTTCGTCAATTTGAGCCTGGTACCCATCTAGATCAAACAGAGAAATTGATAAAATACAGTGACTTCGTCAACAAGGAGCTTATATTATTTTCGATGGCGGATTT
ACAAAGGTCTATTCCCTCAATGGTTGATGGCCTCAAGCCTGGCCAGAGGAAGATCCTTTACTGTTCTTTCAAGAGGAACTTCATCAAAGAAGCAAAAGTTTCTCAATTTT
CCGGTTACGTATCTGAGCATTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGCACCATCATTGGAATGGCACAGGACTTTGTTGGCAGCAACAACATTAATCTTCTT
ATGCCAAACGGACAGTTTGGCACTCGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAGCTTTCAAATGTTACACGGTTCCTTTTCCCGAAAGA
CGATGACAAGCTTCTTAACTACTTAAATGAAGATGGCCAGTCAATTGAACCAACCTGGTACATGCCTATCATACCAACGGTTCTTGTCAATGGAAGTGAAGGAATTGGAA
CTGGTTGGAGTTCATACATTCCAAATTATAATCCTAGAGATATCATTAGAAATGTCAGACGCTTGTTGGATGGTGAAACAATGGTGCCAATGGATCCTTGGTATAGAGGT
TTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGTACTAGTTACACTGTTAGTGGAATTATAGAGGAAGTCAGCGATACGACATTGAGAATAATTGAACTGCC
CGTTCGCAAATGGACTAATGATTATAAGGAATTCCTTGATTCTGTAACGAGAGTTGCAGCAAAGAACGACAAAGACAAAGAAAAAGCAGCGAAGGATCCTTTTATTGAGC
AAGCTGATCACCACAGTGATGACAAAATTGTGTCCATTGATGTTCACTTGACAGAGGAGAACATGATACTGGCCATGCAGGAGGGTTTGAAGAAGAAATTCAAAGTAACA
AATACTATCAGCACCAGCAACATGCATCTCTTTGATGCAAATGGGGTGATTAAGAAATATGACACTCCAGAACAAATTCTTGAGGAATTTTTCCCCCTTAGACTTGAATT
CTATGAGAAAAGAAAGAGAAATCTTTTGGAGAACCTTGAAATGGAGTTGCTCAAATTGGAAAACAAGGTGAGGTTTATCCTTGCTGTTGTGAATGGAGAGATAATAGTAA
GCAATAGAAGAAGAGTTGATTTATTCCATGAGCTTCAAGCGAAAGGCTTTACACCGTTTCCAAAGAAGACTAAATCTGTTGAACCGGAGGTTGCTGGGGCATCTAATGAA
ACAGAGGAAACAGAGGAGAGTCCAGAAGTAAAAGGGGAACGAGTTAGTGATTATGAGTATCTACTTGCTCTAGCAATTGGAACCTTGACCATTGAGAAGGTTCAGGAACT
ATGCAACGATAGGGACAAGCTCAAAGGGGAAGTGGAAGATCTGAGGAAGGCAACCCCCAAGTCTTTGTGGCTAAAAGATCTTGATTCTCTTGAGAAGGAACTTGATGAGA
TGGATAGAAATGATGCTCAGGCTGAGGAGGTAAGAAAACAACAGAGAGTCAAAGCAAATAATGATGTAAAGCCAAGGATCTCAAGGAATGCACCAAAAGCTCCACGTAAC
AGTAAGAAAACTAGCAATTCAGAAGCCGTCACGGAAAGTATGGACACAACATCTAGTTCTACAACAACTGAAGTTGCAAGTAACGCGGTGGTGAAGCCTAAAGGCAAAGC
AGCAGCTCCAAGAAAAGCTCCTGCCAAAAAGGGTAAAGCTGCAGTTGTCAACGATGATGACGAAGATGACGACGACGAAGTGCTCGAGCTTAAAGATCGTCTTGCTGCCT
ACAAAATTGAATCATCTCCAGATCGATCAGAAGTTTCAGCCATGGAAACTGAAGTGCCGCAAGTACAACCGGCCAAGAAGAAAGAACCCAGCAAGAGAGCACCTGCCAAG
AAGAAAACTACTGCCAAGTCCGCACAGAATTCCGACAACGACGACAGCGACGACGACTTCGAAATAAAGGAGATAGCCCCTCCGGCAGCCAAGAAGGGAGGAGGAAGAAA
GGCAGCTGCGGCCAAAACAACCAAGCCCCCTGCAGCAGCCAAGAAGCGAGAGCCGGCGGCGAAGTTGGGGCAGAAACTGATAACTCAAATGCTGGAGCCGGCGGAGAACT
CCGGCATCTCGCCGGAGAAGAAAGTGAGGAAGATAAGAGCATCACCTTTCAACAAGAAAAGCGGCTCCATATTGGGAAGAGTTGGGATAGAAGAAGTAGAGGAAGAAGAA
GAAGAAGAAGGTGGAAATGATGGTAAGATTATGGGCTCTGCTTCTTCTGAGACGACTGAGGAAACCGCCGGAGTTGCTCCGGCGAGAGGAAGATCTCAGAGGGCTAAAAG
AACTCAGGTGAGATATGTGGTTAGTGATTCAGAGAGTGAGCCAGCTTCTGAGGATTCAGACTTTGATGAAAAAGATGCAGACTTTGATGAAGATTGA

mRNA sequence

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Protein sequence

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MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQ
NCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSEPIITKCKESDNWTKVTFKPD
LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITN
QIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQNSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLE
DANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERK
NWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL
MPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRG
FSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKVT
NTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
TEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRVKANNDVKPRISRNAPKAPRN
SKKTSNSEAVTESMDTTSSSTTTEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQVQPAKKKEPSKRAPAK
KKTTAKSAQNSDNDDSDDDFEIKEIAPPAAKKGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
EEEGGNDGKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

Lag0031143 (gene) of Sponge gourd (AG-4) v1 genome