CuGenDBv2

Gene ID	Lag0031232
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	phosphatidyl-N-methylethanolamine N-methyltransferase
Genome location	chr11:6057926..6060969
RNA-Seq Expression	Lag0031232
Synteny	Lag0031232
Gene Ontology terms	GO:0006656 - phosphatidylcholine biosynthetic process (biological process) GO:0032259 - methylation (biological process) GO:0005789 - endoplasmic reticulum membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0000773 - phosphatidyl-N-methylethanolamine N-methyltransferase activity (molecular function) GO:0004608 - phosphatidylethanolamine N-methyltransferase activity (molecular function) GO:0080101 - phosphatidyl-N-dimethylethanolamine N-methyltransferase activity (molecular function)
InterPro domains	IPR007318 - Phospholipid methyltransferase IPR024960 - Phosphatidyl-N-methylethanolamine/Phosphatidylethanolamine N-methyltransferase

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7036543.1 Phosphatidyl-N-methylethanolamine N-methyltransferase [Cucurbita argyrosperma subsp. argyrosperma]

2.3e-81

90.85

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M VLAVIGVLLPFPYYYVLW RPQLWVNLCG W EP KLMAQVS+ LKL+QFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYIKDPQYVGSILSL ACLSWVP QYILLWTMGYVFMMQVES ED  TRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

XP_004137657.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis sativus]

1.6e-82

90.24

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+ AVIGVLLPFPYYYVLWNRPQLWVNLCG  REPCKLMAQVS+ LKL+QFLSI+HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVP +YILLWT+GY+FMM VES ED ATRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

XP_008465151.2 PREDICTED: phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis melo]

3.8e-84

91.46

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LAVIGVLLPFPYYYVLWNRPQLWVNLCG  REPCKLMAQVS+ LKL+QFLSI+HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVP +YILLWT+GY+FMM VES EDPATRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

XP_022153398.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Momordica charantia]

4.0e-81

88.41

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG++A IGVLLPFP+YYVLW RPQLW N CG WREPCKLMA+VSI LKL+QFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYI+DPQYVGSILS+FACLSWVP QYILL T+GYVFMMQVES EDP TRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

XP_038903463.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Benincasa hispida]

2.3e-81

87.2

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LAV+GVLLPFPYYYVLW+RPQLWVNLCG  R+PCKLMAQVS+ LKL+QFLSI HVSSF+WPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVP QYI+LWT+GY+FMM +ES E PATRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CPQ5 phosphatidyl-N-methylethanolamine N-methyltransferase

1.9e-84

91.46

Show/hide

Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LAVIGVLLPFPYYYVLWNRPQLWVNLCG  REPCKLMAQVS+ LKL+QFLSI+HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVP +YILLWT+GY+FMM VES EDPATRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

A0A498HBL2 Phosphatidyl-N-methylethanolamine N-methyltransferase

3.6e-72

80.49

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+ A IGVL PFP+YY LW+ PQ WV LCG  R+PCK+MA VS  LKLIQFLS+  VS+FSWPPPLYFWPL+AFGQFLNFRVYQLLGESG YYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGY+KDPQYVGSILSLFAC+S VPFQYILLWT+GYV M+ +ES EDPATRAKPRS
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

A0A6J1DHC8 phosphatidyl-N-methylethanolamine N-methyltransferase

1.9e-81

88.41

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG++A IGVLLPFP+YYVLW RPQLW N CG WREPCKLMA+VSI LKL+QFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYI+DPQYVGSILS+FACLSWVP QYILL T+GYVFMMQVES EDP TRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

A0A6J1GCG7 phosphatidyl-N-methylethanolamine N-methyltransferase

5.6e-81

90.24

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M VLAVIGVLLPFPYYYVLW RPQLWVNLCG W EP KLMAQVS+ LKL+Q LSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYIKDPQYVGSILSL ACLSWVP QYILLWTMGYVFMMQVES ED  TRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

A0A6J1KB80 phosphatidyl-N-methylethanolamine N-methyltransferase

2.5e-81

90.24

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M VLAVIGVLLPFPYYY+LW RPQLWVNLCG W EP KLMAQVS+ LKL+QFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS
        NIPWVTEFPFGYIKDPQYVGSILSL ACLSWVP QYILLWTMGYVFMMQVES ED  TRAKP+S
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

SwissProt top hits

e value

%identity

Alignment

Q9SAH5 Phosphatidyl-N-methylethanolamine N-methyltransferase

2.3e-68

75.78

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LA IGVLLPFP+Y+ LW   Q WVNLCG  R+P  +MA+VS +LK  Q LS+  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAK
        NIPWVTEFPFG I+DPQYVGSI+SL ACLSWVPFQYILLW++GYVFMM +ES EDP  RAK
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAK

Arabidopsis top hits

e value

%identity

Alignment

AT1G80860.1 phospholipid N-methyltransferase

1.7e-69

75.78

Show/hide

Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LA IGVLLPFP+Y+ LW   Q WVNLCG  R+P  +MA+VS +LK  Q LS+  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAK
        NIPWVTEFPFG I+DPQYVGSI+SL ACLSWVPFQYILLW++GYVFMM +ES EDP  RAK
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAK

AT1G80860.2 phospholipid N-methyltransferase

1.7e-69

75.78

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Query:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LA IGVLLPFP+Y+ LW   Q WVNLCG  R+P  +MA+VS +LK  Q LS+  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCG-WREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAK
        NIPWVTEFPFG I+DPQYVGSI+SL ACLSWVPFQYILLW++GYVFMM +ES EDP  RAK
Subjt:  NIPWVTEFPFGYIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAK

Sequences

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CDS sequence

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ATGGGCGTTTTGGCAGTAATTGGAGTGTTGTTGCCATTTCCGTACTACTACGTCTTATGGAATCGCCCACAGTTGTGGGTGAACTTGTGCGGTTGGCGCGAGCCCTGCAA
ATTGATGGCTCAGGTCTCGATTTTGCTCAAGTTGATTCAGTTCCTCTCCATCCTCCATGTCTCCTCCTTCTCATGGCCGCCGCCTCTCTACTTCTGGCCTCTCATGGCCT
TTGGACAGTTCTTGAACTTCAGGGTCTACCAGTTACTCGGTGAATCCGGTGTTTACTATGGAGTACGGTTTGGGAAGAATATTCCATGGGTTACAGAATTTCCATTTGGA
TATATAAAAGATCCTCAGTATGTGGGAAGCATTTTGAGCCTTTTTGCTTGTCTTTCTTGGGTACCCTTTCAATATATTCTGCTGTGGACAATGGGGTACGTCTTTATGAT
GCAAGTTGAGTCCAATGAAGATCCCGCAACTCGAGCAAAGCCTCGAAGTTGA

mRNA sequence

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Protein sequence

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MGVLAVIGVLLPFPYYYVLWNRPQLWVNLCGWREPCKLMAQVSILLKLIQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGKNIPWVTEFPFG
YIKDPQYVGSILSLFACLSWVPFQYILLWTMGYVFMMQVESNEDPATRAKPRS

Lag0031232 (gene) of Sponge gourd (AG-4) v1 genome