| GenBank top hits | e value | %identity | Alignment |
|---|
| XP_004136210.1 phosphomevalonate kinase, peroxisomal [Cucumis sativus] | 8.4e-271 | 93.89 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVLMTGGYLVLE+PNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTD+KLTSPQLLRESIYKLSLKNQSL+SVSPSQSRNPFVE+AVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAA AKF+DKDN++ALHKLLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCKPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
YL VVNLSLLTGDQEQ+GSA LDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIPI+EVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLN L KLAAEHWDAY++IINSCC+LTSEKWIHQATEPSQQAIIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMR MGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDSTS+V KSWSSLDILALLVREDPRGV LESCDP+T AIT+
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| XP_008466028.1 PREDICTED: phosphomevalonate kinase [Cucumis melo] | 1.1e-270 | 93.89 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVLMTGGYLVLE+PNAGLVLSTNARFYAIVKPIY+EIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVE+AVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAA AKF+DKDN++ALH+LLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCKPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
+L VVNLSLLTGDQEQ+GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIPI+EVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQ+SLDTW+KLSEGNSELETQLN LSKLAAEHWDAY++IINSCC+LTSEKWIHQATEP+QQAIIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDSTS+VIKSWSSLDILALLVREDPRGV LES DP+T AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| XP_022963972.1 phosphomevalonate kinase, peroxisomal-like [Cucurbita moschata] | 9.6e-267 | 92.31 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVL+TGGYLVLE+PNAGLVLSTNARFYAIVKPIYEEIKP SWAWSWTDVKLTSPQLLRESIYKLSLK QSLQSVSPSQ+RNPFVEKAVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAACAKF+D DN++ALHKLLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYG+N KPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
YL VVNLSLLTG+QEQKGSAD+DLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIP+QEVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLS+GNSELETQLN+LSKLAAEHWD+Y++IIN C LTSE+WIHQA+EPSQQ IIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDST++VIKSWS LD LALLVREDPRGV LESCDP+T+AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| XP_023554025.1 phosphomevalonate kinase, peroxisomal-like [Cucurbita pepo subsp. pepo] | 9.6e-267 | 92.31 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVL+TGGYLVLE+PNAGLVLSTNARFYAIVKPIYEEIKP SWAWSWTDVKLTSPQLLRESIYKLSLK QSLQSVSPSQ+RNPFVEKAVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAACAKF+D DNR+ALHKLLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYG+N KPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
YL VVNLSLLTG+QEQKGSAD+DLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIP++EVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLS+GNSELETQLN+LSKLAAEHWD+Y++IIN C LTSE+WIHQA+EPSQQ IIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDST++VIKSWS LD LALLVREDPRGV LESCDP+T+AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| XP_038887930.1 phosphomevalonate kinase, peroxisomal [Benincasa hispida] | 2.1e-269 | 92.9 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVLMTGGYLVLE+PNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVE+AVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAACAKF+DKDN DALHKLLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGK+CKP+VAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
YL VVNLSL TGDQEQ+GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNG+PI+EVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQ+SL+TWR+LSEGNSELE QLN LSKLA+EHWDAY++IIN CC+LTSEKWI+QATEPSQQAIIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLD TMNMEGV+LAGVPGAGGFDAVFAVTLGDS S+V KSWSSLDIL LLVREDPRGV LESCDP+T+AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| TrEMBL top hits | e value | %identity | Alignment |
|---|
| A0A1S3CQ96 Phosphomevalonate kinase | 5.3e-271 | 93.89 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVLMTGGYLVLE+PNAGLVLSTNARFYAIVKPIY+EIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVE+AVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAA AKF+DKDN++ALH+LLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCKPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
+L VVNLSLLTGDQEQ+GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIPI+EVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQ+SLDTW+KLSEGNSELETQLN LSKLAAEHWDAY++IINSCC+LTSEKWIHQATEP+QQAIIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDSTS+VIKSWSSLDILALLVREDPRGV LES DP+T AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| A0A5D3E5W3 Phosphomevalonate kinase | 5.3e-271 | 93.89 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVLMTGGYLVLE+PNAGLVLSTNARFYAIVKPIY+EIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVE+AVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAA AKF+DKDN++ALH+LLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCKPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
+L VVNLSLLTGDQEQ+GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIPI+EVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQ+SLDTW+KLSEGNSELETQLN LSKLAAEHWDAY++IINSCC+LTSEKWIHQATEP+QQAIIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDSTS+VIKSWSSLDILALLVREDPRGV LES DP+T AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| A0A6J1DT44 Phosphomevalonate kinase | 1.7e-264 | 91.32 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKP+YEEIKPDSWAWSWTDVKLTSPQLLRES YKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAACAKF++KDN+DALHKLL+ GLDITILG NEFYSYR+QIEARGLPLTSESLASLPPFSSITFNDEESYGK CKPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
YL VV+LSLLT DQEQKG+ADLDLVH+IAQSAHCIAQGK+GSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIPIQEVI+++LNQKW+HE+TKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTL+LGEPGVGGSSTPSMVGAV+KWQKSDPQKSLD WRKLSE NSELETQLN+LSKLAAE+WDAY++II+SCC+LTSEKWIHQATEPSQQAIIKAL+GAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAMLGIRHHMRLMGEAAGVPIEPDSQT LLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDSTS+VIKSWSSLDIL LLVREDP G+ LES DP+T AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSV I
Subjt: AVSSVHI
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| A0A6J1HGL2 Phosphomevalonate kinase | 4.6e-267 | 92.31 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVL+TGGYLVLE+PNAGLVLSTNARFYAIVKPIYEEIKP SWAWSWTDVKLTSPQLLRESIYKLSLK QSLQSVSPSQ+RNPFVEKAVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAACAKF+D DN++ALHKLLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYG+N KPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
YL VVNLSLLTG+QEQKGSAD+DLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIP+QEVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLS+GNSELETQLN+LSKLAAEHWD+Y++IIN C LTSE+WIHQA+EPSQQ IIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDST++VIKSWS LD LALLVREDPRGV LESCDP+T+AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| A0A6J1HTW0 Phosphomevalonate kinase | 3.0e-266 | 92.11 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVL+TGGYLVLE+PNAGLVLSTNARFYAIVKPIYEE+KPDSWAWSWTDVKLTSPQLLRESIYKLSLK QSLQSVSPSQ+RNPFVEKAVEYC
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
VAAACAKF+D DN+ ALHKLLL GLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYG+N KPEVAKTGLGSSAAMTAAVVAALLN
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
YL VVNLSLLTG+QEQKGSAD+DLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRY+RFSPEVLSSAQAAKNGIP+QEVIV++LNQKWDHERTKFSLPPL
Subjt: YLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPL
Query: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLS+GNSELETQL +LSKLAAEHWD+Y++IIN C LTSE+WIHQA+EPSQQ IIKALLGAR
Subjt: MTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGAR
Query: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
NAML IRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGV+LAGVPGAGGFDAVFAVTLGDST++VIKSWS LD LALLVREDPRGV LESCDP+T+AITS
Subjt: NAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAITS
Query: AVSSVHI
AVSSVHI
Subjt: AVSSVHI
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| SwissProt top hits | e value | %identity | Alignment |
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| P24521 Phosphomevalonate kinase | 1.4e-39 | 30.94 | Show/hide |
Query: SAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLL-RESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYCVAAA
SAPGK L+ GGYLVL+ V+ +AR +A+ P D + +V++ S Q E +Y +S K+ + VS S+NPF+EK + +
Subjt: SAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLL-RESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYCVAAA
Query: CAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQI-EARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLNYLR
D NR+ I I + ++S + E RG N S+ + EV KTGLGSSA + + AL
Subjt: CAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQI-EARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLNYLR
Query: VVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPLMTL
S D E +++H +AQ AHC AQGK+GSGFDV++A YGS RY RF P ++S+ + ++ V + W+ LP +TL
Subjt: VVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPLMTL
Query: VLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCR--LTSEKWIHQATEPSQQAIIKALLGARN
+G+ GS T +V VK W S +SL + +L NS L+ L +L H D I S R T +K+ + TE R+
Subjt: VLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCR--LTSEKWIHQATEPSQQAIIKALLGARN
Query: AMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGD
A+ IR R + + +G IEP QT LLD ++GV+ +PGAGG+DA+ +T D
Subjt: AMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGD
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| Q97UL6 Phosphomevalonate kinase | 1.7e-08 | 26.47 | Show/hide |
Query: ESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLNYLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVY
E L+ LP I +++ + + K KTGLGSS+A T ++ A L + G DL +H +AQ A+ Q +GSGFD++SAV+
Subjt: ESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLNYLRVVNLSLLTGDQEQKGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVY
Query: GSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPLMTLVLGEPGVGGSSTPSMVGAVKKW-QKSDPQKSLDTWRKLSEGNSELETQ
GS Y RF+ K D K +L ++LG G + VG V+K+ +KS+ + R + E N + +
Subjt: GSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPPLMTLVLGEPGVGGSSTPSMVGAVKKW-QKSDPQKSLDTWRKLSEGNSELETQ
Query: LNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGARNAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGF
L L+KL +A +HI LG ++ + GV + + +L+ EG ++A PGAGG
Subjt: LNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGARNAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGF
Query: DAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLES
D++FA LG+ + V ++WS I + V+ED G+ LES
Subjt: DAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLES
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| Q9C6T1 Phosphomevalonate kinase, peroxisomal | 2.3e-199 | 70.67 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
MAVVASAPGKVLMTGGYLVLE+PNAGLVLSTNARFYAIVKPI EE+KP+SWAW WTDVKLTSPQL RES+YKLSL + +LQSVS S SRNPFVE A++Y
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPSQSRNPFVEKAVEYC
Query: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
+AA A + ++++LHKLLL GLDITILG N+FYSYR+QIE+ GLPLT ESL +L PF+SITFN ES G N KPEVAKTGLGSSAAMT AVVAALL+
Subjt: VAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCKPEVAKTGLGSSAAMTAAVVAALLN
Query: YLRVVNLSLLTGDQEQK-GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPP
YL VV+LS +E K G +DLD++H+IAQ++HC+AQGKVGSGFDVS AVYGSQRY+RFSPEVLS AQ A G+P+ EVI +L KWD++RT+FSLPP
Subjt: YLRVVNLSLLTGDQEQK-GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVNVLNQKWDHERTKFSLPP
Query: LMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGA
LM L LGEPG GGSSTPSMVGAVKKWQ SDP+K+ + W+ LS+ N ELET+LN LSKLA +HWD Y +I SC LTSEKW+ ATEP +AIIK LL A
Subjt: LMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIINSCCRLTSEKWIHQATEPSQQAIIKALLGA
Query: RNAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAIT
R AML IR MR MGEAA VPIEP+SQT+LLD+TM+ EGV+LAGVPGAGGFDA+FA+TLGDS + + ++WSS ++LALLVREDP GV LES DP+T IT
Subjt: RNAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLGDSTSDVIKSWSSLDILALLVREDPRGVTLESCDPQTRAIT
Query: SAVSSVHI
S VSS+H+
Subjt: SAVSSVHI
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| Q9UT88 Probable phosphomevalonate kinase | 1.4e-39 | 29.41 | Show/hide |
Query: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLR-ESIYKLSLK------NQSLQSVSPSQSRNPFV
M V SAPGKVL+ GGY+VL+ +GLV+ A+ YA + ++ V++ SPQ + E +Y + +Q ++ ++ NPFV
Subjt: MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKLTSPQLLR-ESIYKLSLK------NQSLQSVSPSQSRNPFV
Query: EKAVEYCVAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCK-PEVAKTGLGSSAAMTA
+ A+ Y + + R L L +T+ N +Y P S P F+ + NC +V KTGLGSSAAM
Subjt: EKAVEYCVAAACAKFLDKDNRDALHKLLLHGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKNCK-PEVAKTGLGSSAAMTA
Query: AVVAALLNYLRVVNLSLLTGDQEQK-GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVN---------
+++ +L +L + L+ TGD+ K + +VH +AQ AHC AQGKVGSGFDV +A +GS Y RF P+++ +P E I N
Subjt: AVVAALLNYLRVVNLSLLTGDQEQK-GSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYIRFSPEVLSSAQAAKNGIPIQEVIVN---------
Query: VLNQKWDHERTKFSLPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIIN-SCCRLTSEKWI
++++KW + F LP L++G+ GGSSTP MV V++WQK +P++S + + D Y +++ C L+SE
Subjt: VLNQKWDHERTKFSLPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNLLSKLAAEHWDAYQHIIN-SCCRLTSEKWI
Query: HQATEPSQQAIIKALLGARNAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLG--DSTSDVIKSWSSLDILALLV
+ ++ IR ++ + A V IEP QT +LD + GV+ GVPGAGGFDA F + + + +VIK+W ++ + V
Subjt: HQATEPSQQAIIKALLGARNAMLGIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVVLAGVPGAGGFDAVFAVTLG--DSTSDVIKSWSSLDILALLV
Query: REDPRGVTLE
G+ +E
Subjt: REDPRGVTLE
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