CuGenDBv2

Gene ID	Lag0034113
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	dCTP pyrophosphatase 1
Genome location	chr3:4521706..4522218
RNA-Seq Expression	Lag0034113
Synteny	Lag0034113
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

XP_004138182.1 dCTP pyrophosphatase 1 [Cucumis sativus]

1.3e-58

95.28

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSK+VKNANKYPV AAF RALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

XP_022921755.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

2.2e-58

95.28

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSK+VKNANKYPV AAFARALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

XP_022933743.1 dCTP pyrophosphatase 1-like isoform X2 [Cucurbita moschata]

2.8e-58

95.28

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        MESR SYEPEKTAKDVSL ELRDRLAEFA+VRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEE+SDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSKIVKNANKYPV AAFARALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

XP_022987438.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

8.2e-58

94.49

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEKTAKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSK+VKNANKYPV AAFARALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

XP_038880679.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

7.4e-59

96.06

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        MES  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSK+VKNANKYPV AAFARALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LP76 dCTP pyrophosphatase 1

6.1e-59

95.28

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSK+VKNANKYPV AAF RALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

A0A5A7UWT3 dCTP pyrophosphatase 1

6.8e-58

93.7

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAA+SK+VKNANKYPV AA  RALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

A0A6J1E6P9 dCTP pyrophosphatase 1

1.0e-58

95.28

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSK+VKNANKYPV AAFARALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

A0A6J1F5P6 dCTP pyrophosphatase 1

1.4e-58

95.28

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        MESR SYEPEKTAKDVSL ELRDRLAEFA+VRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEE+SDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSKIVKNANKYPV AAFARALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

A0A6J1JJF8 dCTP pyrophosphatase 1

4.0e-58

94.49

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Query:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEKTAKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVAAAFARALP
        LGHAALSK+VKNANKYPV AAFARALP
Subjt:  LGHAALSKIVKNANKYPVAAAFARALP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

5.0e-26

51.28

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Query:  ESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ES  +  P   + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  E+  L+EE+SD+L+YLV LA  C +DL
Subjt:  ESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPV
          A L K+  N  +YPV
Subjt:  GHAALSKIVKNANKYPV

Q91VC0 dCTP pyrophosphatase 1

1.7e-26

53.98

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Query:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKIVKNANKYPV
        +SK+  N  +YPV
Subjt:  LSKIVKNANKYPV

Q9H773 dCTP pyrophosphatase 1

3.9e-26

54.24

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Query:  RCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGH
        R S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  E+  L+EE+SDVL+YLV LA  C +DL  
Subjt:  RCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGH

Query:  AALSKIVKNANKYPVAAA
        A LSK+  N  +YP   A
Subjt:  AALSKIVKNANKYPVAAA

Q9QY93 dCTP pyrophosphatase 1

2.3e-26

50.43

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Query:  ESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        E   +  P + + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL
Subjt:  ESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPV
          A +SK+  N  +YPV
Subjt:  GHAALSKIVKNANKYPV

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

1.0e-37

71.84

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Query:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIVKNANK
        VSLQ L  ++ +FA+ R WE+YHSPRNLLLA+VGEVGELSEIFQWKGEV RG P+W   EK HL EE+SDVLLYLVRL+D CG+DLG AAL KI  NA K
Subjt:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIVKNANK

Query:  YPV
        YPV
Subjt:  YPV

Sequences

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CDS sequence

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ATGGAGAGTCGCTGTTCTTACGAACCTGAGAAAACCGCCAAAGACGTCTCACTGCAAGAACTTCGAGACAGACTCGCAGAGTTCGCCCGAGTGCGAGGATGGGAGCAATA
CCACAGCCCTAGAAACCTGCTCCTAGCACTTGTCGGTGAGGTCGGAGAGCTATCGGAGATATTCCAGTGGAAGGGGGAAGTGGAGAGGGGGCTGCCGAACTGGAGCGCGG
CGGAGAAAGAGCATTTGGAAGAAGAAGTGTCGGATGTGTTGCTCTATTTGGTGCGTCTCGCCGACGTGTGTGGCCTTGATCTCGGCCATGCGGCGCTCTCGAAGATCGTA
AAAAATGCGAACAAGTATCCGGTCGCCGCCGCTTTCGCTCGCGCGCTGCCGTGA

mRNA sequence

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Protein sequence

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MESRCSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIV
KNANKYPVAAAFARALP

Lag0034113 (gene) of Sponge gourd (AG-4) v1 genome