CuGenDBv2

Gene ID	Lag0036133
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	DNA excision repair protein ERCC-1
Genome location	chr3:39988424..39989556
RNA-Seq Expression	Lag0036133
Synteny	Lag0036133
Gene Ontology terms	GO:0000710 - meiotic mismatch repair (biological process) GO:0006296 - nucleotide-excision repair, DNA incision, 5'-to lesion (biological process) GO:0006312 - mitotic recombination (biological process) GO:0070914 - UV-damage excision repair (biological process) GO:0000110 - nucleotide-excision repair factor 1 complex (cellular component) GO:0070522 - ERCC4-ERCC1 complex (cellular component) GO:0003684 - damaged DNA binding (molecular function) GO:0003697 - single-stranded DNA binding (molecular function) GO:0004518 - nuclease activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

TYK02347.1 DNA excision repair protein ERCC-1 [Cucumis melo var. makuwa]

3.8e-37

82.2

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS
        ME+G  E+N QQT HKKSKTIIKIPSYQEV +SSQPKSQSFSQAFAFLKSSEFYSPPP P S SSSQSLPAS+ITN R+NDQLDTSS STS   ATP NS
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS

Query:  FSGSSSVSRNAILVSNRQ
         S SSSVSRNAILVSNRQ
Subjt:  FSGSSSVSRNAILVSNRQ

XP_022159707.1 DNA excision repair protein ERCC-1 isoform X1 [Momordica charantia]

2.9e-37

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT
        MEQ +EEDNLQQT HKKSKTIIKIPSYQEV+E SQPK QSFSQAF+FLKSSEFYSPPPNP SASSSQ LP S ITN R+NDQL+TSS STSA+     PT
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT

Query:  NSFSGSSSVSRNAILVSNRQ
        NS SGSSS +RNAILVSNRQ
Subjt:  NSFSGSSSVSRNAILVSNRQ

XP_022159708.1 DNA excision repair protein ERCC-1 isoform X2 [Momordica charantia]

2.9e-37

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT
        MEQ +EEDNLQQT HKKSKTIIKIPSYQEV+E SQPK QSFSQAF+FLKSSEFYSPPPNP SASSSQ LP S ITN R+NDQL+TSS STSA+     PT
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT

Query:  NSFSGSSSVSRNAILVSNRQ
        NS SGSSS +RNAILVSNRQ
Subjt:  NSFSGSSSVSRNAILVSNRQ

XP_038884592.1 DNA excision repair protein ERCC-1 isoform X1 [Benincasa hispida]

2.6e-38

84.75

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSA---TPTNS
        ME+G+EE+NLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPP P SASSSQSL AS+ITN R+NDQLDTSS STSA   TP NS
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSA---TPTNS

Query:  FSGSSSVSRNAILVSNRQ
         S  SSVS NAILVSNRQ
Subjt:  FSGSSSVSRNAILVSNRQ

XP_038884594.1 DNA excision repair protein ERCC-1 isoform X2 [Benincasa hispida]

2.6e-38

84.75

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSA---TPTNS
        ME+G+EE+NLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPP P SASSSQSL AS+ITN R+NDQLDTSS STSA   TP NS
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSA---TPTNS

Query:  FSGSSSVSRNAILVSNRQ
         S  SSVS NAILVSNRQ
Subjt:  FSGSSSVSRNAILVSNRQ

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CIE0 DNA excision repair protein ERCC-1

1.8e-37

82.2

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS
        ME+G  E+N QQT HKKSKTIIKIPSYQEV +SSQPKSQSFSQAFAFLKSSEFYSPPP P S SSSQSLPAS+ITN R+NDQLDTSS STS   ATP NS
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS

Query:  FSGSSSVSRNAILVSNRQ
         S SSSVSRNAILVSNRQ
Subjt:  FSGSSSVSRNAILVSNRQ

A0A5A7T0A2 DNA excision repair protein ERCC-1

1.8e-37

82.2

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS
        ME+G  E+N QQT HKKSKTIIKIPSYQEV +SSQPKSQSFSQAFAFLKSSEFYSPPP P S SSSQSLPAS+ITN R+NDQLDTSS STS   ATP NS
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS

Query:  FSGSSSVSRNAILVSNRQ
         S SSSVSRNAILVSNRQ
Subjt:  FSGSSSVSRNAILVSNRQ

A0A5D3BSF5 DNA excision repair protein ERCC-1

1.8e-37

82.2

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS
        ME+G  E+N QQT HKKSKTIIKIPSYQEV +SSQPKSQSFSQAFAFLKSSEFYSPPP P S SSSQSLPAS+ITN R+NDQLDTSS STS   ATP NS
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTS---ATPTNS

Query:  FSGSSSVSRNAILVSNRQ
         S SSSVSRNAILVSNRQ
Subjt:  FSGSSSVSRNAILVSNRQ

A0A6J1DZL1 DNA excision repair protein ERCC-1 isoform X2

1.4e-37

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT
        MEQ +EEDNLQQT HKKSKTIIKIPSYQEV+E SQPK QSFSQAF+FLKSSEFYSPPPNP SASSSQ LP S ITN R+NDQL+TSS STSA+     PT
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT

Query:  NSFSGSSSVSRNAILVSNRQ
        NS SGSSS +RNAILVSNRQ
Subjt:  NSFSGSSSVSRNAILVSNRQ

A0A6J1E0J7 DNA excision repair protein ERCC-1 isoform X1

1.4e-37

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Query:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT
        MEQ +EEDNLQQT HKKSKTIIKIPSYQEV+E SQPK QSFSQAF+FLKSSEFYSPPPNP SASSSQ LP S ITN R+NDQL+TSS STSA+     PT
Subjt:  MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSAT-----PT

Query:  NSFSGSSSVSRNAILVSNRQ
        NS SGSSS +RNAILVSNRQ
Subjt:  NSFSGSSSVSRNAILVSNRQ

SwissProt top hits

e value

%identity

Alignment

Q9MA98 DNA excision repair protein ERCC-1

4.0e-13

46.09

Show/hide

Query:  EQGDEEDNLQQTAHKKSKT--IIKIPSYQEVIESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSS
        + G++  +L Q   +K KT  +I +PSYQEV+ESSQ K         SQSFSQAFAF+KSS+ YSPPP P+SA++S S P  AS +  ++ +  Q D +S
Subjt:  EQGDEEDNLQQTAHKKSKT--IIKIPSYQEVIESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSS

Query:  PSTSATPTNSFSGSSSVSRNAILVSNRQ
         S++   T S   +++ +RNAILVS+RQ
Subjt:  PSTSATPTNSFSGSSSVSRNAILVSNRQ

Arabidopsis top hits

e value

%identity

Alignment

AT3G05210.1 nucleotide repair protein, putative

2.8e-14

46.09

Show/hide

Query:  EQGDEEDNLQQTAHKKSKT--IIKIPSYQEVIESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSS
        + G++  +L Q   +K KT  +I +PSYQEV+ESSQ K         SQSFSQAFAF+KSS+ YSPPP P+SA++S S P  AS +  ++ +  Q D +S
Subjt:  EQGDEEDNLQQTAHKKSKT--IIKIPSYQEVIESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSS

Query:  PSTSATPTNSFSGSSSVSRNAILVSNRQ
         S++   T S   +++ +RNAILVS+RQ
Subjt:  PSTSATPTNSFSGSSSVSRNAILVSNRQ

Sequences

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CDS sequence

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ATGGAGCAAGGAGACGAAGAAGATAACTTACAGCAAACCGCTCACAAAAAGAGCAAGACCATCATCAAGATACCCTCTTATCAAGAAGTCATCGAAAGCTCACAGCCAAA
ATCACAATCCTTCTCCCAAGCCTTTGCGTTCCTCAAATCCTCTGAATTTTACTCTCCTCCTCCAAACCCAACATCAGCTTCCTCCTCTCAATCCTTGCCCGCTTCTGACA
TCACAAACACAAGAGAAAACGATCAATTAGATACTTCATCTCCTTCAACATCGGCCACTCCAACTAATAGCTTCTCGGGGTCGAGCTCTGTTAGTCGCAATGCCATTCTT
GTGAGCAATAGACAGGTGAGGGTGCAGAGACGTGGGATGAAAGGTTTCAGGGTTGGTGGTGGCATATTGATCTCACGCATTTGCTACTTGTTGATGATGAACCTCTTTTG
CGCCAGTGGTGCTGATTATCTTAATGGAATGTCGATGGTCTTTGAAGAGATCTGTGGTCTAGCATTAACAGATCAAAATCCTCAGGCTTAG

mRNA sequence

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Protein sequence

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MEQGDEEDNLQQTAHKKSKTIIKIPSYQEVIESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSSPSTSATPTNSFSGSSSVSRNAIL
VSNRQVRVQRRGMKGFRVGGGILISRICYLLMMNLFCASGADYLNGMSMVFEEICGLALTDQNPQA

Lag0036133 (gene) of Sponge gourd (AG-4) v1 genome