CuGenDBv2

Gene ID	Lag0036616
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	Flap endonuclease 1
Genome location	chr3:49378370..49384282
RNA-Seq Expression	Lag0036616
Synteny	Lag0036616
Gene Ontology terms	GO:0006284 - base-excision repair (biological process) GO:0043137 - DNA replication, removal of RNA primer (biological process) GO:0090305 - nucleic acid phosphodiester bond hydrolysis (biological process) GO:0005654 - nucleoplasm (cellular component) GO:0005730 - nucleolus (cellular component) GO:0005739 - mitochondrion (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0003677 - DNA binding (molecular function) GO:0008409 - 5'-3' exonuclease activity (molecular function) GO:0017108 - 5'-flap endonuclease activity (molecular function)
InterPro domains	IPR006084 - XPG/Rad2 endonuclease IPR036279 - 5'-3' exonuclease, C-terminal domain superfamily

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KGN66474.2 hypothetical protein Csa_007122 [Cucumis sativus]

8.1e-85

88.33

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        N+  IGG TALKLIRQHGSIE+ILENINKERYQIPDDWPY+EAR+LFKEPLVCTDEEQLDIKWTTPDEEGL+TFLVNENGFNS+RVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVSIKRKVNKCVLRSPKPG Q K+S QA Y SR+KVIG+LGMSMLDHSSKYSGSGPLVMA CF T
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

XP_022159613.1 flap endonuclease 1 isoform X1 [Momordica charantia]

1.1e-86

90.56

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE ILENINKERYQIP+DWPYQEAR+LFKEPLVCTDEEQLDIKWTTPDEEGL+TFLVNENGFNSDRVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGRLESFFKP+TNPSV IKRKV KCV+RSPKPGVQ+KYSPQA YSSRTKVIG+LGMSML+ SSKYSGSGPLVMAVCFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

XP_022931724.1 flap endonuclease 1 isoform X1 [Cucurbita moschata]

1.5e-83

86.67

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIENILENINKERYQIP+ WP+QEAR+LFKEPLVCTDEEQLDIKWTTPDEEGLI+FLVNENGFNSDRVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVS KRKV KCVL+SPKPG+Q KYSPQA Y SRTKVIG+LG  +LDHSSKYSGS PLVMA CFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

XP_023531871.1 flap endonuclease 1 isoform X1 [Cucurbita pepo subsp. pepo]

2.0e-83

86.67

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE+ILENINKERYQIP+ WP+QEAR+LFKEPLVCTDEEQLDIKWTTPDEEGLI+FLVNENGFNSDRVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVS KRKV KCVL+SPKPG+Q KYSPQA Y SRTKVIG+LG  +LDHSSKYSGS PLVMAVCFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

XP_038879461.1 flap endonuclease 1 isoform X1 [Benincasa hispida]

2.1e-88

91.11

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        N+  IGGQTALKLIRQHGSIE ILENINKERYQIPDDWPYQEAR+LFKEPLVCTDEEQLDIKWTTPDEEGL+ FLVNENGFNS+RVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVSIKRKVNKCVLRSPKPG Q K+SPQA YSSRTK IG+LGMSMLDHSSKYSGSGPLVMAVCFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BPA7 Flap endonuclease 1

3.1e-82

86.67

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        N+  IGG TALKLIRQHG+IE ILENINKERYQIPDDWPY+EAR+LFKEPLVCTDEEQLDIKWTTPDEEGL+TFLVNENGFNS+RVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVSIKRKVNK VLR PKPG Q K+S QA   SR+KVIG+LGMSMLDHSSKYSGSGPLVMA CFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

A0A1S3BQ01 Flap endonuclease 1

3.1e-82

86.67

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        N+  IGG TALKLIRQHG+IE ILENINKERYQIPDDWPY+EAR+LFKEPLVCTDEEQLDIKWTTPDEEGL+TFLVNENGFNS+RVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVSIKRKVNK VLR PKPG Q K+S QA   SR+KVIG+LGMSMLDHSSKYSGSGPLVMA CFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

A0A6J1DZA7 Flap endonuclease 1

5.5e-87

90.56

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE ILENINKERYQIP+DWPYQEAR+LFKEPLVCTDEEQLDIKWTTPDEEGL+TFLVNENGFNSDRVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGRLESFFKP+TNPSV IKRKV KCV+RSPKPGVQ+KYSPQA YSSRTKVIG+LGMSML+ SSKYSGSGPLVMAVCFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

A0A6J1EV18 Flap endonuclease 1

7.4e-84

86.67

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIENILENINKERYQIP+ WP+QEAR+LFKEPLVCTDEEQLDIKWTTPDEEGLI+FLVNENGFNSDRVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVS KRKV KCVL+SPKPG+Q KYSPQA Y SRTKVIG+LG  +LDHSSKYSGS PLVMA CFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

A0A6J1I0P7 Flap endonuclease 1

2.2e-83

86.11

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIENILENINKERYQIP+DWP+QEAR+LFKEPLVCTDEEQLDIKWTTPDEEGLI+ LVNENGFNSDRVTKAVEKIKAAKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT
        SQGR+ESFFKP+TNPSVS KRKV KCVL+SPKPG+Q KYSPQA Y SRTKVIG+LG  ++DHS KYSGS PLVMAVCFGT
Subjt:  SQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAVCFGT

SwissProt top hits

e value

%identity

Alignment

B8AW67 Flap endonuclease 1-A

1.3e-45

75.41

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE+ILENINK+RYQIP+DWPYQEAR+LFKEP V  D  +L  KW  PDEEGL+ FLV ENGFN DRVTKA+EKIK AKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRK
        SQGRLESFFKP+ + SV +KRK
Subjt:  SQGRLESFFKPMTNPSVSIKRK

C5YUK3 Flap endonuclease 1-A

1.0e-45

74.59

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE+ILEN+NK+RYQIP+DWPYQEAR+LFKEP V  D  +L  KWT PDEEGLI+FLV +NGFN DRVTKA+EKIK+AKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRK
        SQGRLESFFKP+   S  +KRK
Subjt:  SQGRLESFFKPMTNPSVSIKRK

C6TEX6 Flap endonuclease 1

2.9e-53

83.61

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGG TALKLIRQHGSIENI EN+NKERYQIPD+WPYQEAR+LFKEPLV TDE++LDIKW++PDEEGLITFLVNENGFN DRVTKA+EKIK AKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRK
        SQGRLESFFKP  NPSV IKRK
Subjt:  SQGRLESFFKPMTNPSVSIKRK

O65251 Flap endonuclease 1

1.6e-51

81.15

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE ILEN+NKERYQIP++WPY EARKLFKEP V TDEEQLDIKWT+PDEEG++ FLVNENGFN DRVTKA+EKIK AKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRK
        SQGRLESFFKP+ N SV  KRK
Subjt:  SQGRLESFFKPMTNPSVSIKRK

Q9SXQ6 Flap endonuclease 1-A

1.3e-45

75.41

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE+ILENINK+RYQIP+DWPYQEAR+LFKEP V  D  +L  KW  PDEEGL+ FLV ENGFN DRVTKA+EKIK AKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRK
        SQGRLESFFKP+ + SV +KRK
Subjt:  SQGRLESFFKPMTNPSVSIKRK

Arabidopsis top hits

e value

%identity

Alignment

AT5G26680.1 5'-3' exonuclease family protein

3.9e-53

80.65

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE ILEN+NKERYQIP++WPY EARKLFKEP V TDEEQLDIKWT+PDEEG++ FLVNENGFN DRVTKA+EKIK AKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRKVN
        SQGRLESFFKP+ N SV  KRK N
Subjt:  SQGRLESFFKPMTNPSVSIKRKVN

AT5G26680.2 5'-3' exonuclease family protein

1.1e-52

81.15

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Query:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS
        ++  IGGQTALKLIRQHGSIE ILEN+NKERYQIP++WPY EARKLFKEP V TDEEQLDIKWT+PDEEG++ FLVNENGFN DRVTKA+EKIK AKNKS
Subjt:  NVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKS

Query:  SQGRLESFFKPMTNPSVSIKRK
        SQGRLESFFKP+ N SV  KRK
Subjt:  SQGRLESFFKPMTNPSVSIKRK

Sequences

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CDS sequence

Show/hide CDS sequence

ATGAGGCGAGCGACGGGAGGTGCGAGTTGGTGGACAACGGCGACTTGCAGAAGCGAATGTTCGGGTCGCAGGCGGAGGCGGTGCGACGACGTAGGAGGCAACAGTACCAA
AGTGGCAGCAAAAAAGGCCACCAACGTTGGAAGTATAGGGGGGCAGACTGCTCTCAAGCTTATCCGTCAACATGGGTCTATAGAAAACATATTAGAGAACATAAATAAAG
AAAGGTACCAAATTCCAGATGATTGGCCTTATCAAGAGGCACGAAAGCTTTTTAAAGAACCACTAGTATGTACTGACGAAGAGCAACTTGATATTAAGTGGACTACTCCG
GATGAAGAAGGTTTAATAACATTTTTGGTGAATGAGAATGGGTTCAACAGTGATAGAGTCACAAAGGCAGTAGAAAAAATTAAAGCAGCCAAGAACAAGTCATCACAGGG
CCGGTTGGAGTCATTTTTCAAGCCCATGACTAATCCTTCAGTATCCATTAAGCGAAAGGTAAACAAATGTGTACTTAGGTCTCCCAAACCAGGAGTCCAGCAAAAATACT
CACCGCAAGCTTTGTATTCGTCTAGGACAAAGGTCATTGGCAACCTAGGCATGTCAATGTTAGACCATTCTTCCAAGTACTCGGGGTCAGGGCCATTAGTTATGGCTGTT
TGCTTCGGCACATGA

mRNA sequence

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Protein sequence

Show/hide protein sequence

MRRATGGASWWTTATCRSECSGRRRRRCDDVGGNSTKVAAKKATNVGSIGGQTALKLIRQHGSIENILENINKERYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTP
DEEGLITFLVNENGFNSDRVTKAVEKIKAAKNKSSQGRLESFFKPMTNPSVSIKRKVNKCVLRSPKPGVQQKYSPQALYSSRTKVIGNLGMSMLDHSSKYSGSGPLVMAV
CFGT

Lag0036616 (gene) of Sponge gourd (AG-4) v1 genome