CuGenDBv2

Gene ID	Lag0036692
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	short-chain dehydrogenase/reductase family 42E member 1-like
Genome location	chr2:421431..422127
RNA-Seq Expression	Lag0036692
Synteny	Lag0036692
Gene Ontology terms	GO:0006694 - steroid biosynthetic process (biological process) GO:0016021 - integral component of membrane (cellular component) GO:0003854 - 3-beta-hydroxy-delta5-steroid dehydrogenase activity (molecular function)
InterPro domains	IPR028110 - Transmembrane protein 254

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7024083.1 Short-chain dehydrogenase/reductase family 42E member 1 [Cucurbita argyrosperma subsp. argyrosperma]

3.0e-75

92.11

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLP EIYKVGV+N FSYLKA+EELGYVPMV+PKEGMAATISYWQERKRKSLDGPTIY WLFCVVGM+I+FC AFLPDVGPVPFFK ISLFFFRSIQVVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFLIAFLLHVGEG YAWFLARKVDPANSRGWFWQTFALGFFSLR LLKRARS
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

XP_004145560.1 short-chain dehydrogenase/reductase family 42E member 1 [Cucumis sativus]

1.2e-74

90.79

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLPAEIYKVGV+N FSYLKAKEELGY P+V+PKEGMAATISYWQER+RKSLDGPTIYVWLFC+VGM+ILFCAAFLPDVGPVPFFKAISLFFFRSI+V+RM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFL+A LLHVGE IYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRAR+
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

XP_022937306.1 short-chain dehydrogenase/reductase family 42E member 1-like [Cucurbita moschata]

1.0e-75

92.76

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLP EIYKVGV+N FSYLKA+EELGYVPMV+PKEGMAATISYWQERKRKSLDGPTIY WLFCVVGM+I+FCAAFLPDVGPVPFFK ISLFFFRSIQVVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFLIAFLLHVGEG YAWFLARKVDPANSRGWFWQTFALGFFSLR LLKRARS
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

XP_022975358.1 short-chain dehydrogenase/reductase family 42E member 1-like [Cucurbita maxima]

3.0e-75

92.11

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLP EIYKVGV+N FSYLKA+EELGYVPMV+PKEGMAATISYWQ+RKRKSLDGPTIY WLFCVVGM+I+FCAAFLPDVGPVPFFK ISLFFFRSIQVVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFLIAFLLHVGEG YAWFLARKVDPANSRGWFWQTFALGFFSLR LLKRARS
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

XP_023536108.1 short-chain dehydrogenase/reductase family 42E member 1-like [Cucurbita pepo subsp. pepo]

1.0e-75

92.76

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLP EIYKVGV+N FSYLKA+EELGYVPMV+PKEGMAATISYWQERKRKSLDGPTIY WLFCVVGM+I+FCAAFLPDVGPVPFFK ISLFFFRSIQVVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFLIAFLLHVGEG YAWFLARKVDPANSRGWFWQTFALGFFSLR LLKRARS
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L3F5 3Beta_HSD domain-containing protein

5.6e-75

90.79

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLPAEIYKVGV+N FSYLKAKEELGY P+V+PKEGMAATISYWQER+RKSLDGPTIYVWLFC+VGM+ILFCAAFLPDVGPVPFFKAISLFFFRSI+V+RM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFL+A LLHVGE IYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRAR+
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

A0A1S3BV84 short-chain dehydrogenase/reductase family 42E member 1

6.2e-74

90.13

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLPAEIYKVGV+N FSYLKAKEELGY PMV+PKEGMAATIS+WQE+KRKSLDGPTIYVWL+CVVGM+ILFCAAFLPDVGPVPFFKAISLFFFRSI+VVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFL+AFLLHVGE IYAWFLARKVDPANS GWFWQT ALG FSLRFLLKRAR+
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

A0A5A7VCF3 Short-chain dehydrogenase/reductase family 42E member 1

6.2e-74

90.13

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLPAEIYKVGV+N FSYLKAKEELGY PMV+PKEGMAATIS+WQE+KRKSLDGPTIYVWL+CVVGM+ILFCAAFLPDVGPVPFFKAISLFFFRSI+VVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFL+AFLLHVGE IYAWFLARKVDPANS GWFWQT ALG FSLRFLLKRAR+
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

A0A6J1FA01 short-chain dehydrogenase/reductase family 42E member 1-like

5.1e-76

92.76

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLP EIYKVGV+N FSYLKA+EELGYVPMV+PKEGMAATISYWQERKRKSLDGPTIY WLFCVVGM+I+FCAAFLPDVGPVPFFK ISLFFFRSIQVVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFLIAFLLHVGEG YAWFLARKVDPANSRGWFWQTFALGFFSLR LLKRARS
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

A0A6J1IIZ5 short-chain dehydrogenase/reductase family 42E member 1-like

1.5e-75

92.11

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        MLP EIYKVGV+N FSYLKA+EELGYVPMV+PKEGMAATISYWQ+RKRKSLDGPTIY WLFCVVGM+I+FCAAFLPDVGPVPFFK ISLFFFRSIQVVRM
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS
        VFLIAFLLHVGEG YAWFLARKVDPANSRGWFWQTFALGFFSLR LLKRARS
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

SwissProt top hits	e value	%identity	Alignment
No hits found

Arabidopsis top hits

e value

%identity

Alignment

AT2G33630.1 NAD(P)-binding Rossmann-fold superfamily protein

5.9e-61

70.2

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Query:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM
        +LPAE+YKVGV + FSYLKAKEELGYVP  S KEGMAATISYWQERKR+SLDGPT++ W+   +GM+ LF A +LPD+GPVPF +AI LFFFR+I +V+ 
Subjt:  MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRM

Query:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRAR
        VF++A +LHV EGIYAWFLA++VDP N+ GWF QT ALGFFS+RFLLKRA+
Subjt:  VFLIAFLLHVGEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRAR

Sequences

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CDS sequence

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ATGCTTCCTGCTGAGATTTACAAGGTCGGCGTCAACAATAATTTCTCGTATCTTAAAGCCAAGGAGGAGCTTGGCTATGTTCCAATGGTGAGTCCAAAGGAGGGCATGGC
TGCGACCATCTCATATTGGCAGGAGAGGAAGAGGAAGAGTCTTGATGGGCCAACAATATATGTCTGGCTTTTTTGTGTTGTCGGAATGAACATCCTGTTTTGTGCTGCCT
TCCTTCCAGACGTTGGACCTGTTCCATTTTTCAAAGCTATCAGCCTTTTCTTCTTCAGGTCAATTCAAGTGGTGAGAATGGTGTTTCTTATAGCCTTTCTACTGCATGTT
GGTGAGGGTATTTATGCATGGTTCTTAGCAAGAAAGGTGGATCCTGCTAACTCAAGGGGATGGTTTTGGCAGACTTTTGCTCTAGGCTTCTTTTCCTTGCGCTTCTTGTT
GAAAAGAGCAAGGAGTTAA

mRNA sequence

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Protein sequence

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MLPAEIYKVGVNNNFSYLKAKEELGYVPMVSPKEGMAATISYWQERKRKSLDGPTIYVWLFCVVGMNILFCAAFLPDVGPVPFFKAISLFFFRSIQVVRMVFLIAFLLHV
GEGIYAWFLARKVDPANSRGWFWQTFALGFFSLRFLLKRARS

Lag0036692 (gene) of Sponge gourd (AG-4) v1 genome