CuGenDBv2

Gene ID	Lag0040378
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	3-oxo-5-alpha-steroid 4-dehydrogenase 1-like
Genome location	chr13:4304472..4304936
RNA-Seq Expression	Lag0040378
Synteny	Lag0040378
Gene Ontology terms	GO:0006629 - lipid metabolic process (biological process) GO:0016021 - integral component of membrane (cellular component) GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors (molecular function)
InterPro domains	IPR039357 - 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6573901.1 3-oxo-5-alpha-steroid 4-dehydrogenase 1, partial [Cucurbita argyrosperma subsp. sororia]

1.7e-36

69.53

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVFAPP SLF+NV+TVV  VVVAM+GLSEARGR+LQYSKFWNAN      SL+QFKLPS LGMLLAYTPA  AGVVSLW FP+EDRR LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HFLKRDLEV+++  + S    D  +
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

KAG6575776.1 Very-long-chain enoyl-CoA reductase, partial [Cucurbita argyrosperma subsp. sororia]

5.7e-37

70.31

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVFAPP SLF+NVMTVV  VVVAM+GLSEARGR+LQYSKFWNAN      SL+QFKLPS LGMLLAYTPA  AGVVSLW FP+EDRR LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HFLKRDLEV+++  + S    D  +
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

XP_022945516.1 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like [Cucurbita moschata]

7.4e-37

69.53

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVFAPP SLF+NV+TVV  VVVAM+GLSEARGR+LQYSKFWNAN  ++  SL+QFKLPS LGMLLAYTPA  AGVVSLW FP+EDRR LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HFLKRDLEV+++  + S    D  +
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

XP_022968321.1 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like [Cucurbita maxima]

1.1e-35

67.97

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVFAPP SLF+NV+TVV  VVVAM+GLSEARGR+LQYSKFWNAN      SL++FKLPS LGMLLAYTPA  AGV+SLW FP+EDRR LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HFLKRDLEV+++  + S    D  +
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

XP_023542215.1 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like [Cucurbita pepo subsp. pepo]

1.7e-36

69.53

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVFAPP SLF+NV+TVV  VVVAM+GLSEARGR+LQYSKFWNAN      SL+QFKLPS LGMLLAYTPA  AGVVSLW FP+EDRR LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HFLKRDLEV+++  + S    D  +
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KWK8 S5A_REDUCTASE domain-containing protein

5.7e-35

64.06

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M TL EFVF PP+S FVNVMTVVSS +VA++GLSEARG++L+YSKFW++N    ++  K F L ++LGML+AY PAF AGVVSLWLFP EDRRILLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L++HF KR+LEV++L  + S  A D V+
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

A0A1S3BGK3 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like

2.8e-34

63.28

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVF PPSS FVNVMTVVSS +VA++GLSEARG++LQYSKFWN N   N+   K F L ++LGMLLAY PAF  GVVS WLFP+EDRRI++LKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L++HF KR+LEV++L  + S  A   V+
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

A0A5D3CDA5 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like

2.8e-34

63.28

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVF PPSS FVNVMTVVSS +VA++GLSEARG++LQYSKFWN N   N+   K F L ++LGMLLAY PAF  GVVS WLFP+EDRRI++LKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L++HF KR+LEV++L  + S  A   V+
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

A0A6J1G134 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like

3.6e-37

69.53

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVFAPP SLF+NV+TVV  VVVAM+GLSEARGR+LQYSKFWNAN  ++  SL+QFKLPS LGMLLAYTPA  AGVVSLW FP+EDRR LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HFLKRDLEV+++  + S    D  +
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

A0A6J1HUJ4 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like

5.2e-36

67.97

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  L EFVFAPP SLF+NV+TVV  VVVAM+GLSEARGR+LQYSKFWNAN      SL++FKLPS LGMLLAYTPA  AGV+SLW FP+EDRR LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HFLKRDLEV+++  + S    D  +
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

SwissProt top hits	e value	%identity	Alignment
No hits found

Arabidopsis top hits

e value

%identity

Alignment

AT5G16010.1 3-oxo-5-alpha-steroid 4-dehydrogenase family protein

4.4e-19

42.19

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Query:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA
        M  +  FV+ PP S+ +N M+VV    +A IG SE RG +L+YSKF  ++        +   + SR GMLL YTPAF A   S ++ P +D R LLLKSA
Subjt:  MSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSA

Query:  LIVHFLKRDLEVMYLSLFISLCASDCVL
        L +HF KR  EV+++  +    A D  L
Subjt:  LIVHFLKRDLEVMYLSLFISLCASDCVL

Sequences

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CDS sequence

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ATGGCGGCGATGAGTACTTTAATGGAGTTTGTTTTTGCGCCGCCGTCTTCACTGTTCGTGAACGTGATGACGGTGGTGAGCTCGGTGGTGGTGGCGATGATAGGGCTTTC
GGAAGCGAGAGGAAGGAATTTGCAGTATTCGAAATTCTGGAATGCGAATGGCGGTACGAATTCGTCTTCGTTGAAGCAGTTCAAGCTTCCGTCCAGGTTAGGGATGCTAT
TGGCTTATACTCCGGCGTTTTTTGCCGGCGTTGTGTCGTTGTGGCTCTTTCCGGATGAGGATCGGAGGATTCTTCTGCTTAAGTCTGCTCTCATCGTGCATTTCTTGAAG
AGAGACCTCGAGGTAATGTATCTGTCTCTGTTTATCTCTCTGTGTGCTTCTGATTGTGTTCTGAATTTCGATCTGATCCTGGAAATCGATTGTGTAGATTGTGGAATGAA
CTGCTTCTTCTTGCATTATTCGTGA

mRNA sequence

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Protein sequence

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MAAMSTLMEFVFAPPSSLFVNVMTVVSSVVVAMIGLSEARGRNLQYSKFWNANGGTNSSSLKQFKLPSRLGMLLAYTPAFFAGVVSLWLFPDEDRRILLLKSALIVHFLK
RDLEVMYLSLFISLCASDCVLNFDLILEIDCVDCGMNCFFLHYS

Lag0040378 (gene) of Sponge gourd (AG-4) v1 genome