CuGenDBv2

Gene ID	Lsi01G008140
Organism	Lagenaria siceraria USVL1VR-Ls (Bottle gourd (USVL1VR-Ls) v1)
Description	Isochorismatase domain-containing protein
Genome location	chr01:6448624..6450805
RNA-Seq Expression	Lsi01G008140
Synteny	Lsi01G008140
Gene Ontology terms	GO:0019365 - pyridine nucleotide salvage (biological process) GO:0008936 - nicotinamidase activity (molecular function)
InterPro domains	IPR000868 - Isochorismatase-like IPR036380 - Isochorismatase-like superfamily IPR044717 - Nicotinamidase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6594908.1 Nicotinamidase 1, partial [Cucurbita argyrosperma subsp. sororia]

2.3e-82

66.53

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MVSEV+ELLKE+LPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQHD+QISQMVEESAR ARVFCEKKWP+FAFLDSH PDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------
        TDE+KLVPALQWLENE NVT +CKDCIDGF+G LEKDGSNVF+DWVKNNQIKV                                               
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------

Query:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL
                        LMHHIGLY+ARGRGAKVVSEVSIK L
Subjt:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL

XP_008440534.1 PREDICTED: nicotinamidase 1 [Cucumis melo]

7.7e-86

69.42

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MV EVMELLKEHLPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQH+KQISQMVEESARLARVFCEKKWP+FAFLDSHHPDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------
        TDESKLVPALQWLENEANVT RCKDCIDGFLG LEKDGSN+FIDWVK NQIK                                                
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------

Query:  --------------VELMHHIGLYIARGRGAKVVSEVSIKPL
                       ELMHHIGLY+ARGRGAKVVSEVSIKPL
Subjt:  --------------VELMHHIGLYIARGRGAKVVSEVSIKPL

XP_022962913.1 nicotinamidase 1 [Cucurbita moschata]

8.0e-83

66.94

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MVSEV+ELLKE+LPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQHD+QISQMVEESARLARVFCEKKWP+FAFLDSH PDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------
        TDE+KLVPALQWLENE NVT +CKDCIDGF+G LEKDGSNVF+DWVKNNQIKV                                               
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------

Query:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL
                        LMHHIGLY+ARGRGAKVVSEVSIK L
Subjt:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL

XP_023002980.1 nicotinamidase 1 [Cucurbita maxima]

2.5e-84

68.18

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MVSEV+ELLKE+LPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWP+FAFLDSHHPDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------
        TDE+KLVPALQWLENE NVT +CKDCIDGF+G LEKDGSNVFIDWVKNNQIKV                                               
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------

Query:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL
                        LMHHIGLY+ARGRGAKVVSEVSIK L
Subjt:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL

XP_038881297.1 nicotinamidase 1 [Benincasa hispida]

8.3e-88

70.25

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MVSEVMELLKEHLPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQHDKQISQMVEES RLARVFCEKKWP+FAFLDSHHPD+PEDPYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------
        TDESKLVPALQWLENEANVT RCKDCIDG LGSLEKDGSNVFIDWVK NQIKV                                               
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------

Query:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL
                       ELMHHIGLY+ARGRGAKVVSEVSIKP+
Subjt:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KG59 Catalytic

7.3e-82

66.67

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MV EVMELLKEHLP+ QEPFVLSGD+N GLVLVD+VNGFCTVGAGNLAPKQH++QISQMVEESARLARVFCEKKWP+FAF DSHHPDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------
        TDESKLVPALQWLENEANVT RCKDCIDGFLG LEKDGSN+FIDWVK NQIK                                                
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------

Query:  --------------VELMHHIGLYIARGRGAKVVSEVSIK
                       ELMHH+GLYIARGRGAKVVSEVS K
Subjt:  --------------VELMHHIGLYIARGRGAKVVSEVSIK

A0A1S3B1Y8 nicotinamidase 1

3.7e-86

69.42

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MV EVMELLKEHLPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQH+KQISQMVEESARLARVFCEKKWP+FAFLDSHHPDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------
        TDESKLVPALQWLENEANVT RCKDCIDGFLG LEKDGSN+FIDWVK NQIK                                                
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------

Query:  --------------VELMHHIGLYIARGRGAKVVSEVSIKPL
                       ELMHHIGLY+ARGRGAKVVSEVSIKPL
Subjt:  --------------VELMHHIGLYIARGRGAKVVSEVSIKPL

A0A5D3CLP4 Nicotinamidase 1

3.7e-86

69.42

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MV EVMELLKEHLPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQH+KQISQMVEESARLARVFCEKKWP+FAFLDSHHPDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------
        TDESKLVPALQWLENEANVT RCKDCIDGFLG LEKDGSN+FIDWVK NQIK                                                
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIK------------------------------------------------

Query:  --------------VELMHHIGLYIARGRGAKVVSEVSIKPL
                       ELMHHIGLY+ARGRGAKVVSEVSIKPL
Subjt:  --------------VELMHHIGLYIARGRGAKVVSEVSIKPL

A0A6J1HG67 nicotinamidase 1

3.9e-83

66.94

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MVSEV+ELLKE+LPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQHD+QISQMVEESARLARVFCEKKWP+FAFLDSH PDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------
        TDE+KLVPALQWLENE NVT +CKDCIDGF+G LEKDGSNVF+DWVKNNQIKV                                               
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------

Query:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL
                        LMHHIGLY+ARGRGAKVVSEVSIK L
Subjt:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL

A0A6J1KQH8 nicotinamidase 1

1.2e-84

68.18

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Query:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG
        MVSEV+ELLKE+LPV QEPFVLSGDVNTGLVLVD+VNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWP+FAFLDSHHPDIPE PYPPHCIAG
Subjt:  MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAG

Query:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------
        TDE+KLVPALQWLENE NVT +CKDCIDGF+G LEKDGSNVFIDWVKNNQIKV                                               
Subjt:  TDESKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV-----------------------------------------------

Query:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL
                        LMHHIGLY+ARGRGAKVVSEVSIK L
Subjt:  ---------------ELMHHIGLYIARGRGAKVVSEVSIKPL

SwissProt top hits

e value

%identity

Alignment

Q8S8F9 Nicotinamidase 1

1.8e-61

48.95

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Query:  VMELLKEHLPV-AQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAGTDE
        + + LK+ +PV  +EP +L+ D + GLV+VD+VNGFCT+G+GN+AP +H++QIS+MVEESA+LAR FC++KWPV AF+DSHHPDIPE PYPPHCI GT+E
Subjt:  VMELLKEHLPV-AQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAGTDE

Query:  SKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV--------------------------------------------------
        S+LVPAL+WLE+E   T R KDCI+GF+GS+E DGSNVF+DWVK  QIKV                                                  
Subjt:  SKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV--------------------------------------------------

Query:  ------------ELMHHIGLYIARGRGAKVVSEVSIK
                    ELMHH+GLY+A+GRGA+VVS++S +
Subjt:  ------------ELMHHIGLYIARGRGAKVVSEVSIK

Arabidopsis top hits

e value

%identity

Alignment

AT2G22570.1 nicotinamidase 1

1.3e-62

48.95

Show/hide

Query:  VMELLKEHLPV-AQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAGTDE
        + + LK+ +PV  +EP +L+ D + GLV+VD+VNGFCT+G+GN+AP +H++QIS+MVEESA+LAR FC++KWPV AF+DSHHPDIPE PYPPHCI GT+E
Subjt:  VMELLKEHLPV-AQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAGTDE

Query:  SKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV--------------------------------------------------
        S+LVPAL+WLE+E   T R KDCI+GF+GS+E DGSNVF+DWVK  QIKV                                                  
Subjt:  SKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV--------------------------------------------------

Query:  ------------ELMHHIGLYIARGRGAKVVSEVSIK
                    ELMHH+GLY+A+GRGA+VVS++S +
Subjt:  ------------ELMHHIGLYIARGRGAKVVSEVSIK

AT2G22570.2 nicotinamidase 1

2.9e-59

Show/hide

Query:  VMELLKEHLPV-AQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAGTDE
        + + LK+ +PV  +EP +L+ D + GLV+VD+VNGFCT+G+GN+AP +H++QIS+MVEESA+LAR FC++KWPV AF+DSHHPDIPE PYPPHCI GT+E
Subjt:  VMELLKEHLPV-AQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAGTDE

Query:  SKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV
        S+LVPAL+WLE+E   T R KDCI+GF+GS+E DGSNVF+DWVK  QIKV
Subjt:  SKLVPALQWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKV

Sequences

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CDS sequence

Show/hide CDS sequence

ATGGTCTCGGAGGTTATGGAGTTATTGAAGGAGCACCTTCCAGTAGCTCAAGAGCCTTTCGTTTTGTCCGGTGACGTCAACACCGGCCTCGTCCTCGTCGATATCGTTAA
TGGCTTCTGCACCGTCGGCGCTGGAAATTTGGCTCCGAAACAGCACGACAAGCAAATTTCTCAAATGGTGGAGGAATCGGCAAGACTCGCCAGAGTTTTCTGCGAGAAAA
AGTGGCCTGTATTCGCCTTTCTTGATTCTCATCATCCGGATATTCCAGAGGATCCCTATCCTCCTCATTGCATTGCTGGAACAGACGAATCCAAATTAGTTCCAGCCTTG
CAATGGCTCGAAAATGAGGCGAATGTGACGTCGAGATGCAAAGATTGCATCGATGGATTTCTAGGTAGTTTGGAAAAAGATGGCTCTAACGTTTTCATCGATTGGGTGAA
AAACAATCAGATCAAAGTCGAGCTGATGCACCACATAGGCCTGTACATTGCAAGGGGGAGAGGAGCCAAGGTGGTATCGGAGGTTTCAATTAAACCACTATGA

mRNA sequence

Show/hide mRNA sequence

AAATTATTATCAAGGTGGACTCCCTTCTTTGACCAACCTTCCTGTTACGAACGACAGGCCTCTCGCATTTGATTTGTTCCCCTTTACCAGAAGAAGAAGAAGACGATGGT
CTCGGAGGTTATGGAGTTATTGAAGGAGCACCTTCCAGTAGCTCAAGAGCCTTTCGTTTTGTCCGGTGACGTCAACACCGGCCTCGTCCTCGTCGATATCGTTAATGGCT
TCTGCACCGTCGGCGCTGGAAATTTGGCTCCGAAACAGCACGACAAGCAAATTTCTCAAATGGTGGAGGAATCGGCAAGACTCGCCAGAGTTTTCTGCGAGAAAAAGTGG
CCTGTATTCGCCTTTCTTGATTCTCATCATCCGGATATTCCAGAGGATCCCTATCCTCCTCATTGCATTGCTGGAACAGACGAATCCAAATTAGTTCCAGCCTTGCAATG
GCTCGAAAATGAGGCGAATGTGACGTCGAGATGCAAAGATTGCATCGATGGATTTCTAGGTAGTTTGGAAAAAGATGGCTCTAACGTTTTCATCGATTGGGTGAAAAACA
ATCAGATCAAAGTCGAGCTGATGCACCACATAGGCCTGTACATTGCAAGGGGGAGAGGAGCCAAGGTGGTATCGGAGGTTTCAATTAAACCACTATGAGGAAGTCAATTG
CTGTCTGCCTTTATTGTTAATAAAATAAGCTCTGCTTTATATAAACATAAAGACATCTTTGTGTATGGAATATTTTTAAGGTAACCTAATTGCATTAGATAGCAGCTTTA
AGGATAATAATTAAGTATATAACAATATTTTTAAAGAATACTGATAGACTTTATCACCAATGATCTATTACTAATAGACTCTTACCATTGATATGGTCTATCACTAATAG
ACTCCTACCATCGATATGGTCTATCACTAATCACTATATTTACAATTGCCCCATAAATATAAGGATAGATTTCATTTAAAATTTGTTGTTCTTTTTCTGTATCTATATCA
AGATTGTGTCTTTTTACAAATTGAAATTTAAA

Protein sequence

Show/hide protein sequence

MVSEVMELLKEHLPVAQEPFVLSGDVNTGLVLVDIVNGFCTVGAGNLAPKQHDKQISQMVEESARLARVFCEKKWPVFAFLDSHHPDIPEDPYPPHCIAGTDESKLVPAL
QWLENEANVTSRCKDCIDGFLGSLEKDGSNVFIDWVKNNQIKVELMHHIGLYIARGRGAKVVSEVSIKPL

Lsi01G008140 (gene) of Bottle gourd (USVL1VR-Ls) v1 genome