CuGenDBv2

Gene ID	Lsi01G020320
Organism	Lagenaria siceraria USVL1VR-Ls (Bottle gourd (USVL1VR-Ls) v1)
Description	DNA-directed DNA polymerase
Genome location	chr01:28019889..28023980
RNA-Seq Expression	Lsi01G020320
Synteny	Lsi01G020320
Gene Ontology terms	GO:0006261 - DNA-dependent DNA replication (biological process) GO:0071897 - DNA biosynthetic process (biological process) GO:0003677 - DNA binding (molecular function) GO:0003887 - DNA-directed DNA polymerase activity (molecular function) GO:0016787 - hydrolase activity (molecular function)
InterPro domains	IPR002298 - DNA polymerase A IPR020045 - DNA polymerase I-like, H3TH domain IPR036279 - 5'-3' exonuclease, C-terminal domain superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008449676.1 PREDICTED: DNA polymerase I [Cucumis melo]

1.0e-51

88.19

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDL           A LRSDLP YMVPFTTRDLLFKKPEDNGEKFTSLLTA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAE FSADPIIRRVLYLWKKL+KN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

XP_022149355.1 uncharacterized protein LOC111017796 isoform X1 [Momordica charantia]

7.6e-52

87.4

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFTSL+TA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

XP_022149356.1 uncharacterized protein LOC111017796 isoform X2 [Momordica charantia]

2.0e-52

84.85

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Query:  ISLNAGVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFT
        + L+ GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFT
Subjt:  ISLNAGVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFT

Query:  SLLTAIGAYAEGFSADPIIRRVLYLWKKLEKN
        SL+TAIGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  SLLTAIGAYAEGFSADPIIRRVLYLWKKLEKN

XP_022149357.1 uncharacterized protein LOC111017796 isoform X3 [Momordica charantia]

7.6e-52

87.4

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFTSL+TA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

XP_022149360.1 uncharacterized protein LOC111017796 isoform X5 [Momordica charantia]

7.6e-52

87.4

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFTSL+TA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BMJ7 DNA-directed DNA polymerase

4.8e-52

88.19

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDL           A LRSDLP YMVPFTTRDLLFKKPEDNGEKFTSLLTA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAE FSADPIIRRVLYLWKKL+KN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

A0A6J1D5H5 DNA-directed DNA polymerase

3.7e-52

87.4

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFTSL+TA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

A0A6J1D5H7 DNA-directed DNA polymerase

3.7e-52

87.4

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFTSL+TA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

A0A6J1D7Q6 DNA-directed DNA polymerase

3.7e-52

87.4

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFTSL+TA
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLEKN
        IGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLEKN

A0A6J1D847 uncharacterized protein LOC111017796 isoform X2

9.7e-53

84.85

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Query:  ISLNAGVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFT
        + L+ GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERI+KMLVTNA QAILSK+L           AILRSDLP+YMVPFTTRDLLFKKPEDNGEKFT
Subjt:  ISLNAGVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFT

Query:  SLLTAIGAYAEGFSADPIIRRVLYLWKKLEKN
        SL+TAIGAYAEGFSADPIIRRVLYLWKKLEKN
Subjt:  SLLTAIGAYAEGFSADPIIRRVLYLWKKLEKN

SwissProt top hits

e value

%identity

Alignment

O34996 DNA polymerase I

8.0e-04

36.54

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDL
        GV G+G   A++L+ +F ++E LL+ +D+V  +++K+ L    +QA++SK+L
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDL

P52026 DNA polymerase I

6.6e-06

33.33

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GV GIG   AV+L+ +FGT+EN+L  +D+++ E++K+ L    + A+LSK L           A +  D PV +   T  D+++K   ++ EK  +L   
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IG
        +G
Subjt:  IG

Q04957 DNA polymerase I

1.0e-06

35.29

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GV GIG   AV+L+ +FGT+EN+L  +D+++ E++K+ L  + E A+LSK L           A +R D PV +    + D +  + ED  EK  +L   
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IG
        +G
Subjt:  IG

Arabidopsis top hits

e value

%identity

Alignment

AT3G52050.1 5'-3' exonuclease family protein

2.7e-39

64.8

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNV+AV+LI+RFGTLENLLQ VD++++ +IK+ L+ +A+QAILSK L           A+LRSDLP Y+VPF T+DL FKKPEDNGEK +SLL A
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLE
        I  YAEGFSADP+IRR   LW+KLE
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLE

AT3G52050.2 5'-3' exonuclease family protein

2.7e-39

64.8

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNV+AV+LI+RFGTLENLLQ VD++++ +IK+ L+ +A+QAILSK L           A+LRSDLP Y+VPF T+DL FKKPEDNGEK +SLL A
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLE
        I  YAEGFSADP+IRR   LW+KLE
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLE

AT3G52050.3 5'-3' exonuclease family protein

2.7e-39

64.8

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNV+AV+LI+RFGTLENLLQ VD++++ +IK+ L+ +A+QAILSK L           A+LRSDLP Y+VPF T+DL FKKPEDNGEK +SLL A
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLE
        I  YAEGFSADP+IRR   LW+KLE
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLE

AT3G52050.4 5'-3' exonuclease family protein

2.7e-39

64.8

Show/hide

Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA
        GVDGIGNV+AV+LI+RFGTLENLLQ VD++++ +IK+ L+ +A+QAILSK L           A+LRSDLP Y+VPF T+DL FKKPEDNGEK +SLL A
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEKFTSLLTA

Query:  IGAYAEGFSADPIIRRVLYLWKKLE
        I  YAEGFSADP+IRR   LW+KLE
Subjt:  IGAYAEGFSADPIIRRVLYLWKKLE

AT3G52050.5 5'-3' exonuclease family protein

8.5e-09

68.42

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Query:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKM
        GVDGIGNV+AV+LI+RFGTLENLLQ VD++++ +IK++
Subjt:  GVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKM

Sequences

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CDS sequence

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mRNA sequence

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ATGTCTTCTATCGACTTGATGGTGCTTGATGTTCTTATATCGCTAAATGCAGGAGTCGATGGAATTGGAAATGTCAATGCTGTGCAACTTATCACTAGATTCGGCACGTT
AGAAAATTTGTTGCAACATGTTGATCAAGTGGAAGATGAACGTATTAAGAAGATGTTGGTAACAAATGCCGAACAAGCTATCTTGAGCAAGGACCTGGTAATTTCCCTTC
AGTTTTATTGGGGCACTCATGCAATCTTGCGATCTGACCTTCCAGTCTACATGGTACCATTTACCACCAGAGATCTTTTATTCAAGAAACCGGAGGATAATGGGGAGAAA
TTCACAAGCCTCTTAACTGCGATTGGTGCATATGCAGAAGGGTTCTCAGCTGATCCAATAATCAGGAGAGTACTCTACTTATGGAAGAAGCTAGAAAAAAATTAGTTATT
GGTGTCTATATGTTCAATCTGTGTGCACACTTTGTTTCATGTAAATTTGGTTTTGTTGTATAGTTGGAGATATTAGAGAGCTTAGAAATCACATTATTCTTCTTTATGAA
TACCCCTTTCTCCTTGTTTTTCATAGCCTTTTAGCAAAGAAAATAGGAAACGCAAGAAGTTTCAGCTTAACATGTTATGGAGTATCCCTTGCTATGAAGGACTGAACTGG
CTTCTCCCGTTGATTGATTATTTGAACATTCCAACCATATGATTGGTTCTTTAGAAAATGGAGGTATTTTGTTATTAGGAGTATTTTCATATAATTAAATTTACTGTGAT
TCATTTGCTTTAAAGATTGATGATTTGACATCTACACTATTGAAAGATGGTTCTAACGTGGATGAGGCACATTTCATAGTTGTGCAAAAGCTTATACTGTTGA

Protein sequence

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MSSIDLMVLDVLISLNAGVDGIGNVNAVQLITRFGTLENLLQHVDQVEDERIKKMLVTNAEQAILSKDLVISLQFYWGTHAILRSDLPVYMVPFTTRDLLFKKPEDNGEK
FTSLLTAIGAYAEGFSADPIIRRVLYLWKKLEKN

Lsi01G020320 (gene) of Bottle gourd (USVL1VR-Ls) v1 genome