CuGenDBv2

Gene ID	Lsi03G012010
Organism	Lagenaria siceraria USVL1VR-Ls (Bottle gourd (USVL1VR-Ls) v1)
Description	DNA topoisomerase 2
Genome location	chr03:22478248..22485813
RNA-Seq Expression	Lsi03G012010
Synteny	Lsi03G012010
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0048368.1 DNA topoisomerase 2 [Cucumis melo var. makuwa]

0.0e+00

88.79

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Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYESW+ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG+LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSNVTR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRK    R LL+NLEMELLKLENKVRFILAVVN EI VSNR+KVDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQAKGFTPFPKKTKS EPE+AGASNETDEAEESPEVVKGER+SDYEYLLA+ IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR
        DE+DRNDAQ ME+RKQQRDK+N DLKPKISRNAPKAPRNSKKTSN ETV ESMDTT SSTTTE                      ANNPVVKPKGKAAPR
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR

Query:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD
        KAPAKKK   GKAAV D D+DDEVLELKDRLAAYKIESSPEPSE                +S METEV +VQAAKKKEPSKRA AKKKTTAKSAQIS SD
Subjt:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD

Query:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-
        D D+DDFEIKEV P AAKKGGGR     AAAN KTTK PAA  KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEEE G ED 
Subjt:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-

Query:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED
         KV+GSASSET+EEVA F  A GRS+RANRTQVRYV+SDSD++ VS+ SDFDE EASLDED
Subjt:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0e+00

86.96

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Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNA NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYE+W+++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ +LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSN TR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML+GE MLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRK    RNLLENLE ELLKLENKVRFILAVVNGEIIVSNRR+VDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQ KGFTPFPKKTKS EPEVAGASNETDEAEESPEVVKGERVSDYEYLLA+AIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLD LEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP
        DEMDRNDAQA EVRKQQR K+N D+KPKISRNAPKAPRNSKKTSN+ET+ ESMD TTSSSTTTE                      ANNPVVKPKGKAAP
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP

Query:  RKAPAKKKQPQGKAAVL-DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA
        RKAPAKK   QGKAAVL DD+DDEVLELKDRLAAYK+ESSPEPSE                +S METEVP+VQ AAKKKEPSKRAAAKKKTTAKSAQIS 
Subjt:  RKAPAKKKQPQGKAAVL-DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA

Query:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAA------AAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EE
         D D+ DFEIKE+APPAAKKGGGRKAAANAKTTK           A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IGEEE   EE
Subjt:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAA------AAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EE

Query:  AGNEDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED
        AGNE K++GSASSETT EEVAR P ARGRSQR NRTQVRYVVSDSD++ V E SDFDEEA+LDED
Subjt:  AGNEDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED

XP_008461811.1 PREDICTED: DNA topoisomerase 2 [Cucumis melo]

0.0e+00

88.79

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Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYESW+ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG+LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSNVTR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRK    R LL+NLEMELLKLENKVRFILAVVN EI VSNR+KVDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQAKGFTPFPKKTKS EPE+AGASNETDEAEESPEVVKGER+SDYEYLLA+ IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR
        DE+DRNDAQ ME+RKQQRDK+N DLKPKISRNAPKAPRNSKKTSN ETV ESMDTT SSTTTE                      ANNPVVKPKGKAAPR
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR

Query:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD
        KAPAKKK   GKAAV D D+DDEVLELKDRLAAYKIESSPEPSE                +S METEV +VQAAKKKEPSKRA AKKKTTAKSAQIS SD
Subjt:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD

Query:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-
        D D+DDFEIKEV P AAKKGGGR     AAAN KTTK PAA  KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEEE G ED 
Subjt:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-

Query:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED
         KV+GSASSET+EEVA F  A GRS+RANRTQVRYV+SDSD++ VS+ SDFDE EASLDED
Subjt:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED

XP_011651769.2 DNA topoisomerase 2 [Cucumis sativus]

0.0e+00

87.83

Show/hide

Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSNA NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQ+LWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADG+RLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCK GDNWT+VTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSAS+ Q EPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIAN+VMT VNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKR NSFGSACELTP+FLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYE+W+ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG+LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSNVTR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGT+YTVSGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRK    R LL+NLEMELLKLENKVRFILAVVN EI VSNR+KVDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQAKGFTPFPKKTKS EPE+AGASNETDEAEESPEVVKGER+SDYEYLLA+ IGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLD LEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR
        DEMDRNDAQ ME+RKQQR+K+NIDLKPK+SRNAPKAPRNSKKTSN ETV ESMDTT SSTTTE                      ANNPVVKPKGKAAPR
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR

Query:  KAPAKKKQPQGKAAVL----DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQV--QAAKKKEPSKRAAAKKKTTAKSAQ
        KAPAKKK   GKAAVL    DDEDDEVLELKDRLAAYKIESSPEPSE                +S METEV +V  QAAKKKEPSKRA AKKKTTAKSAQ
Subjt:  KAPAKKKQPQGKAAVL----DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQV--QAAKKKEPSKRAAAKKKTTAKSAQ

Query:  ISASDDDED-DFEIKEVAPPAAKKGGGR------KAAANAKTTKPPAAAAKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE
        IS SDDD D DFEIKEV PPAAKKGGGR       AA N+KTTKPPAA AKLGQKLITQMLEP AENSGISPEKKVRKIRASPFNKKSGS+LGRTIGEEE
Subjt:  ISASDDDED-DFEIKEVAPPAAKKGGGR------KAAANAKTTKPPAAAAKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE

Query:  E-EAGNEDKVVGSASSETTEEVARFPAARGRSQRANR-TQVRYVVSDSDNDV-SEASDFDE-EASLDED
        E E  +E K++GSAS ET+EEV     ARGRS+RANR TQVRYV+SDSD +V S+ SDFDE EASLDED
Subjt:  E-EAGNEDKVVGSASSETTEEVARFPAARGRSQRANR-TQVRYVVSDSDNDV-SEASDFDE-EASLDED

XP_038905935.1 DNA topoisomerase 2 [Benincasa hispida]

0.0e+00

87.78

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Query:  MAVEKKRPLQNSNATNVDSNP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM
        MAVEKKRPLQNSNA NVDS+P AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRS+SYVPGLYKIFDEILVNAADNKQRDPSM
Subjt:  MAVEKKRPLQNSNATNVDSNP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKS
        DSVKV+IDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKR+KKYKQVFNDNMGKKS
Subjt:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKS

Query:  EPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIV
        EPIITKCK GDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP+KSFQDYVDLYLKSASTFQTEPPKRYHIKPN+RWEIV
Subjt:  EPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN
        VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQI+NYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKR NSFGS CELTPEFLKN
Subjt:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN

Query:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL
                  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL
Subjt:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL

Query:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTM
        NVREA+SKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTM
Subjt:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTM

Query:  PEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKEL
        PEYESW+ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT +LIKYSDFVNKEL
Subjt:  PEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKEL

Query:  ILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASS
        ILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN GGKDHASS
Subjt:  ILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASS

Query:  RYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMD
        RYIYTKLSNVTR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII+NVRRMLDG TMLPMD
Subjt:  RYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMD

Query:  PWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENM
        PWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDT LRI+ELPVRRWTNDYKDFLDSVT+VA+KHDKDKEKAAK+PFIEQADHHSDDKIVSIDVHLTEENM
Subjt:  PWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENM

Query:  LLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDL
        LLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRL+FYEKRK    RNLLENLEMELLKLENKVRFIL VVN EIIV NRRKVDL
Subjt:  LLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDL

Query:  FHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKE
        FHELQAKGFTPFPKK KS EPEVAGAS+E DEAEESPEVVK  RVSDYEYLL++ IGTLTIEKVQELCN+RDKLKGEVDDLRKATPK+LWLNDLDSLEKE
Subjt:  FHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKE

Query:  LDEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP
        LDEMD NDAQAME RK+QRDK N DLKPKISRNAPKAPRN KKTSNAE V ESMDTT SSTT E                      ANNPVVKPKGKAAP
Subjt:  LDEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP

Query:  RKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISAS-
        RKAPAKK    GKAAVLDD+DDEVLELKDRLAAYKIESSPEPSE                   METEVPQVQAAKKKEP+KRAAAKKKTTAKSAQ+S S 
Subjt:  RKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISAS-

Query:  ---DDDEDDFEIKEVAPPAAKKGGGR-----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIG------E
           DDD+DDFE+KEVAPPA KKGGGR      AA NAKTTKPPAAAAKLGQKLIT+MLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIG      E
Subjt:  ---DDDEDDFEIKEVAPPAAKKGGGR-----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIG------E

Query:  EEEEAGNEDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEE
        EEEE+G E+KV+GSASSETT EEVA    ARGRS RANRTQVRYVVSD D++ VSE SD DE+
Subjt:  EEEEAGNEDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEE

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CFK5 DNA topoisomerase 2

0.0e+00

88.79

Show/hide

Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYESW+ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG+LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSNVTR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRK    R LL+NLEMELLKLENKVRFILAVVN EI VSNR+KVDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQAKGFTPFPKKTKS EPE+AGASNETDEAEESPEVVKGER+SDYEYLLA+ IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR
        DE+DRNDAQ ME+RKQQRDK+N DLKPKISRNAPKAPRNSKKTSN ETV ESMDTT SSTTTE                      ANNPVVKPKGKAAPR
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR

Query:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD
        KAPAKKK   GKAAV D D+DDEVLELKDRLAAYKIESSPEPSE                +S METEV +VQAAKKKEPSKRA AKKKTTAKSAQIS SD
Subjt:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD

Query:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-
        D D+DDFEIKEV P AAKKGGGR     AAAN KTTK PAA  KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEEE G ED 
Subjt:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-

Query:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED
         KV+GSASSET+EEVA F  A GRS+RANRTQVRYV+SDSD++ VS+ SDFDE EASLDED
Subjt:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED

A0A5A7TZH5 DNA topoisomerase 2

0.0e+00

88.79

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Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYESW+ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG+LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSNVTR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRK    R LL+NLEMELLKLENKVRFILAVVN EI VSNR+KVDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQAKGFTPFPKKTKS EPE+AGASNETDEAEESPEVVKGER+SDYEYLLA+ IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR
        DE+DRNDAQ ME+RKQQRDK+N DLKPKISRNAPKAPRNSKKTSN ETV ESMDTT SSTTTE                      ANNPVVKPKGKAAPR
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPR

Query:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD
        KAPAKKK   GKAAV D D+DDEVLELKDRLAAYKIESSPEPSE                +S METEV +VQAAKKKEPSKRA AKKKTTAKSAQIS SD
Subjt:  KAPAKKKQPQGKAAVLD-DEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASD

Query:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-
        D D+DDFEIKEV P AAKKGGGR     AAAN KTTK PAA  KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEEE G ED 
Subjt:  D-DEDDFEIKEVAPPAAKKGGGR----KAAANAKTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNED-

Query:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED
         KV+GSASSET+EEVA F  A GRS+RANRTQVRYV+SDSD++ VS+ SDFDE EASLDED
Subjt:  -KVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDE-EASLDED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

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Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNA NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYE+W+++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ +LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSN TR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML+GE MLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRK    RNLLENLE ELLKLENKVRFILAVVNGEIIVSNRR+VDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQ KGFTPFPKKTKS EPEVAGASNETDEAEESPEVVKGERVSDYEYLLA+AIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLD LEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP
        DEMDRNDAQA EVRKQQR K+N D+KPKISRNAPKAPRNSKKTSN+ET+ ESMD TTSSSTTTE                      ANNPVVKPKGKAAP
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP

Query:  RKAPAKKKQPQGKAAVL-DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA
        RKAPAKK    GK AVL DD+DDEVLELKDRLAAYK+ESSPEPSE                +S METEVP+VQ AAKKKEPSKRAAAKKKTTAKSAQIS 
Subjt:  RKAPAKKKQPQGKAAVL-DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA

Query:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANA---KTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EEAGN
         D D+ DFEIKE+APPAAKKGGGRKAAANA   KTTK     A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IGEEE   EEAGN
Subjt:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANA---KTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EEAGN

Query:  EDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED
        E K++GSASSETT EEVAR P ARGRSQR NRTQVRYVVSDSD++ V E SDFDEEA+LDED
Subjt:  EDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

87.07

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Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNA NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQ+LWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYE+W+++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ +LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSN TR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML+GE MLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRK    RNLLENLE ELLKLENKVRFILAVVNGEIIVSNRR+VDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQ KGFTPFPKKTKS EPEVAGASNETDEAEESPEVVKGERVSDYEYLLA+AIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLD LEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP
        DEMDRNDAQA EVRKQQR K+N D+KPKISRNAPKAPRNSKKTSN+ET+ ESMD TTSSSTTTE                      ANNPVVKPKGKAAP
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP

Query:  RKAPAKKKQPQGKAAVL-DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA
        RKAPAKK   QGK AVL DD+DDEVLELKDRLAAYK+ESSPEPSE                +S METEVP+VQ AAKKKEPSKRAAAKKKTTAKSAQIS 
Subjt:  RKAPAKKKQPQGKAAVL-DDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA

Query:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANA---KTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EEAGN
         D D+ DFEIKE+APPAAKKGGGRKAAANA   KTTK     A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IGEEE   EEAGN
Subjt:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANA---KTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EEAGN

Query:  EDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED
        E K++GSASSETT EEVAR P ARGRSQR NRTQVRYVVSDSD++ V E SDFDEEA+LDED
Subjt:  EDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED

A0A6J1IWX9 DNA topoisomerase 2

0.0e+00

Show/hide

Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVE KRPLQNSNA NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQ+LW+YENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        S+KV ID EQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND
        TLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKN 
Subjt:  TLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKND

Query:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
                 VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
Subjt:  TDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
        VREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI
        EYE+W+++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ +LIKYSDFVNKELI
Subjt:  EYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP
        YIYTKLSN TR L              F      +  +L+++ +      YMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRMLDGE MLPMDP
Subjt:  YIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDP

Query:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML
        WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDDK VSI+VHLTEENM+
Subjt:  WYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENML

Query:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF
        LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRK    RNLLENLE ELLKLENKVRFILAVVNGEIIVSNRR+VDLF
Subjt:  LAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLF

Query:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL
        HELQ KGFTPFPKKTKS EPEVAGASNETDEAEESPEVVKGERVSDYEYLLA+AIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLD LEKEL
Subjt:  HELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKEL

Query:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP
        DEMDRNDAQA EVRKQQR K+N D+KPKISRNAPKAPRNSKKTSN+ET+ ESMD  TSSSTTTE                      ANNPVVKPKGKAAP
Subjt:  DEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMD-TTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAP

Query:  RKAPAKKKQPQGKAAVLDDE-DDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA
        RKAPAKK   QGKAAVLDD+ DDEVLELKDRLAAYK+ESSPEPSE                +S METEVP+VQ AAKKKEPSKRAAAKKKTTAKSAQIS 
Subjt:  RKAPAKKKQPQGKAAVLDDE-DDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQ-AAKKKEPSKRAAAKKKTTAKSAQISA

Query:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANA---KTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EEAGN
         D D+ DFEIKE+APPAAKKGGGRKAAANA   KTTK     A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IGEEE   EEAGN
Subjt:  SDDDEDDFEIKEVAPPAAKKGGGRKAAANA---KTTKPPAAAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEE---EEAGN

Query:  EDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED
        E K++GSASSETT EEVAR P ARGRSQR NRTQVRYVVSDSD++ V E SDFDEEA LDED
Subjt:  EDKVVGSASSETT-EEVARFPAARGRSQRANRTQVRYVVSDSDND-VSEASDFDEEASLDED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

59.39

Show/hide

Query:  KKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SNA N+      P KTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQ+LWVYEND+MVHR++SYVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPIIT
         ID E N +SV+NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVF++NMG K EP+IT
Subjt:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPIIT

Query:  KCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSE
        KCK  +NWTKVTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  KSF+DY DL+LK A   +  P  R H K  +RWEI ++LS+
Subjt:  KCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSE

Query:  GQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNDTDCC
        GQFQQVSFVN I+TIKGGTHVDYITNQI  Y+M  VNKK K+ANVKAH VK++LWVF+N+LIDNP+FDSQTKETLT R  SFGS C++    LK+     
Subjt:  GQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNDTDCC

Query:  KYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
                KSGI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREA
Subjt:  KYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQI +N+EIQ IK+ILGLQQ KEY+N K+LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELILFSM
        W+E L  +A+ W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKKK E RK W+R FEPGT  D   +LI Y DFVNKELILFS 
Subjt:  WRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELILFSM

Query:  ADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        AD                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT
Subjt:  ADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRG
        +LS VTR L              F      +  +L+++ K      YMPIIP VLVNGSEGIGTGWSSY+PNYNPR+II NVRR+L+GE ++PMDPWY+G
Subjt:  KLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRG

Query:  FSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQ
        F GTIEK+A KEGG  Y V+G + E+ + T RI ELP+R+WT DYK FL+S+T        D     KDP IE    + DD IV I++ +  E +   +Q
Subjt:  FSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQ

Query:  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLFHELQ
        EGL KKFKLT+T+STSNMHLFDA G  KK+DTPEQILEEFFPLRL++YEK K      +L NL   LL L+NKVRFIL VVNGEIIVSNR+K +L  EL+
Subjt:  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLFHELQ

Query:  AKGFTPFPKKTKSAEPEVAGASNETDEAEESPE--------VVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSL
         KGFTP P+K KS +P+VAGA+++  E +E  E         V+G    DY+ LL++ IGTLT+E VQ+L +++ + + E + L      SLWL DLD  
Subjt:  AKGFTPFPKKTKSAEPEVAGASNETDEAEESPE--------VVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSL

Query:  EKELDEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNP--VVKPK
        EK+LDE+D   A+    R  Q  K       K ++  P+  +N+KK  + E  PE+    +SS   E+ V                   A  P  V KPK
Subjt:  EKELDEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNP--VVKPK

Query:  GKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTA----
        G+AAP+K   K            + +D++  L++RLAAY IESS E S+                   ME+E  Q +AA KK+ +KR  AKKK++     
Subjt:  GKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTA----

Query:  --KSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAK------TTKPPAAAAK--------LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKS
             +++  DDD+DDFE  +      KKGG + AA NAK        K PAA  K         GQKL+T ML+PAE +G SPEKKVRK+R SPFNKKS
Subjt:  --KSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAK------TTKPPAAAAK--------LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKS

Query:  GSILGRTIGEEEEEAGNEDKVVGSASS-----ETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDE
        GSILGR     ++ +   D   GSAS+     +   E+A  P AR R QRANRTQ++Y +S+S+++     D DE+A L +
Subjt:  GSILGRTIGEEEEEAGNEDKVVGSASS-----ETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDE

P08096 DNA topoisomerase 2

0.0e+00

45.27

Show/hide

Query:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVY--ENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPS
        M   ++ PL  +N  N +SN       +   YQ+ +  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++++YVPGLYKIFDEI+VNAADNK RDP+
Subjt:  MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVY--ENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKK
        M+++KV +D E N IS++NNG G+P+EIH +EK+Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFSTEFV+ETAD +R+KKYKQ + DNM +K
Subjt:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKK

Query:  SEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEI
        SEP+IT  K+ D +TK+TFKPDLAKF M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ +  F+ YV++YL S +    EPP+  +   N+RW++
Subjt:  SEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLK
           +S+GQF+QVSFVN ISTI+GGTHV+Y+ N+I + +  VV K+NK A VKA  +K+Y+ VF+N  I+NPSFDSQTKETLT + ++FGS C L+ +FLK
Subjt:  VVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLK

Query:  NDTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKL
                      KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKL
Subjt:  NDTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKL

Query:  LNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYT
        LNVREAS  QI  NKEIQ IK+I+G    K Y++ K LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T R   V +FYT
Subjt:  LNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYT

Query:  MPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKE
        +PEYE W+E+   N  GW IKYYKGLGTS   + + YF  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T   I   DF+N+E
Subjt:  MPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKE

Query:  LILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHAS
        LI FSMAD  RSIPS+VDGLKPGQRK+++  FKRN + E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLL+PNGQFGTR+ GGK+ ++
Subjt:  LILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHAS

Query:  SRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPM
        SRY+ T LS + R L              F+     +  + + E +      Y+PI+P VLVNG+EGIGTGWS+++PNYNP+DI  N+R ML+GE +  M
Subjt:  SRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPM

Query:  DPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEEN
         PWYRGF G+I K A       Y +SGII ++ +  + I ELP+R WT D K++L++      K  K         FI   + H  +  V  +V LTE  
Subjt:  DPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEEN

Query:  MLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVD
        M  A+ E L+ KFKL+ T +TSNM  FDA+G IKKYD+ E IL EF+ +RL  Y++RK     +++  LE    +  N+ RFI  ++ GE++VS ++K D
Subjt:  MLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVD

Query:  LFHELQAKGFTPF--PKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSL
        L  EL+ K F P   PKK    + EV    N   E E+S +V + E    Y YLL+M + +LT E+  EL   +D++  E+D L K TPK LWL+DLD+ 
Subjt:  LFHELQAKGFTPF--PKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSL

Query:  EKELDE-MDRNDAQAMEVRKQQRDKSN-IDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTE-----------SLVCSVSFTLHIGINLNDFH
        E   ++ MD    + +E  +  RD  N    KP+      + PR    +S++  V +   + S  +TT            S     S  ++I    ++ H
Subjt:  EKELDE-MDRNDAQAMEVRKQQRDKSN-IDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTE-----------SLVCSVSFTLHIGINLNDFH

Query:  --FTANNPVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIV-----ENLLPSLNAISVMETEVPQVQAAKKK
              N + K  G  +     ++K+        +D ED    +   ++AA       + ++     I      ++LLPS    S+  + +   +A+ K 
Subjt:  --FTANNPVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIV-----ENLLPSLNAISVMETEVPQVQAAKKK

Query:  EPSKRAAAKKKTTAKSAQISASDDDEDDF----------------EIKEVAPPAAKKGGGRKAAANAKT
        +  K ++ KK+         + +DD+DDF                E  E +    +K   R+AAA  KT
Subjt:  EPSKRAAAKKKTTAKSAQISASDDDEDDF----------------EIKEVAPPAAKKGGGRKAAANAKT

P30182 DNA topoisomerase 2

0.0e+00

60.15

Show/hide

Query:  KRPLQNSNATNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNA NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ+LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNATNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV
        P+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  +TE P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN

Query:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL
                     KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLL
Subjt:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL

Query:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFY
        NVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY
Subjt:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFY

Query:  TMPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNK
        +MPEYE W+ESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNK
Subjt:  TMPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNK

Query:  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHA
        ELILFSMADLQRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD A
Subjt:  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHA

Query:  SSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLP
        S+RYI+TKLS VTR L              F      +  +L+++ +      YMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L+GE+M+P
Subjt:  SSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLP

Query:  MDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEE
        MDPWYRGF GTIEKTA+KEGG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    ++D+K V  D+ L+EE
Subjt:  MDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEE

Query:  NMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKV
        NML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++    N+E+ELLKLENK RFILAV++GEIIV+ R+K 
Subjt:  NMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKV

Query:  DLFHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERV-------SDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWL
        D+  +L+ KGFTPFP+K +S E  +AGA ++ D AEE  E++            S+Y+YLLAMAI +LTIEKV+EL  DRDK+   V D++K TPKSLWL
Subjt:  DLFHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERV-------SDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWL

Query:  NDLDSLEKELDEMDRNDAQAMEV--RKQQRDKSNIDLKPKISRNAPKAP---RNSKKTSNAETVPESMDTTSSSTTTESLV-----------CSVSFTLH
        +DL+SL+KEL+++D  DAQ  +     Q++ ++      K+ R APK P   + +KK S +ET   S     +      +V            S S T  
Subjt:  NDLDSLEKELDEMDRNDAQAMEV--RKQQRDKSNIDLKPKISRNAPKAP---RNSKKTSNAETVPESMDTTSSSTTTESLV-----------CSVSFTLH

Query:  IGINLNDFHFTANN--PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQA
           +  D   T NN   VVKPKG+       AKKK P   AA  + E+DE+L+L  RLA Y   S+P                                 
Subjt:  IGINLNDFHFTANN--PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQA

Query:  AKKKEPSKRAAAKKKTTAKSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAAAAKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPF
                   A    TA++++  A DDD+DD  + EVAP    K GGRK AA  K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPF
Subjt:  AKKKEPSKRAAAKKKTTAKSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAAAAKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPF

Query:  NKKSGSILGRTIGEEEEEAGNEDKVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDED
        NKKS S++ R    +EEE  + + V G++SSE +       +A  R QRANR ++ YV+SDS+++ +  S+FD+    ++D
Subjt:  NKKSGSILGRTIGEEEEEAGNEDKVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

45.01

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Query:  EKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N N     ++ A   K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR +S+VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPII
        V ID E+  ISV N+G G+P+++H E K+Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFST+F++E AD K  K YKQ F +NM  K +P I
Subjt:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPII

Query:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS
        T  +   ++TK+TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + ++SF+ Y++LY       +   PK Y+ K ++RWE+ VTLS
Subjt:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS

Query:  -EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNDT
         E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDSQTKETLT + +SFGS CE + +F+K   
Subjt:  -EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNDT

Query:  DCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL
        D         +KSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLL
Subjt:  DCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL

Query:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTM
        NVR+ S+K +  N EI  I  ILGL+ GK Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+LLR+P FLVEFITPIVK    N   +SFYTM
Subjt:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTM

Query:  PEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG-RLIKYSDFVNKE
        PE+  WRE+   N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + +DRK W+ +   GT L+Q G + + YSDF+NKE
Subjt:  PEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG-RLIKYSDFVNKE

Query:  LILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHAS
        L+LFS+AD +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMAQ+FVGSNNINLL P G +GTR  GGKD +S
Subjt:  LILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHAS

Query:  SRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK---YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPW
        +RYI+T+L+++ R +           + +   P  S      K+ +   Y+P+IP +LVNG  GIGTGWSS +PNYNPRD+I+N+R  +DG+ + P+ PW
Subjt:  SRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK---YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPW

Query:  YRGFSGTIE-KTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSV----TRVASKHDKDKEKA------AKDPFIEQADHHSDD----K
        YRGF G+IE    +K  G  Y   GI +++SD    I ELP+  WT DY++ LD +    TR   K +K+K+ A      AK    +++    DD    K
Subjt:  YRGFSGTIE-KTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSV----TRVASKHDKDKEKA------AKDPFIEQADHHSDD----K

Query:  IVSIDV------------HLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKL
        +    V            H   + +    +  ++K FKL +T++ +NM +FD  G I+++ T   + E FFPLR++ Y+ RK      L E L  E  +L
Subjt:  IVSIDV------------HLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKL

Query:  ENKVRFILAVVNGEIIVSNRRKVDLFHELQAKGFTPFPKK--TKSAEPEVAGASNETDE------AEESPEVVKGERVSD---YEYLLAMAIGTLTIEKV
         NK RFILAVVN E+++SN +KVDL ++L+   F     K   KSA  ++    N  DE      ++E  +  + E+  D   Y+YLL++ + +LT+E+V
Subjt:  ENKVRFILAVVNGEIIVSNRRKVDLFHELQAKGFTPFPKK--TKSAEPEVAGASNETDE------AEESPEVVKGERVSD---YEYLLAMAIGTLTIEKV

Query:  QELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTE
        ++L  +RD  K E D L     + ++  DLD+LEK LD+ D  D       +  + ++     P+  + + K  +++K+    + V     T    TTT+
Subjt:  QELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEMDRNDAQAMEVRKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTE

Query:  SLVCSVSFTLHIGINLNDFHFTANN---PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAI
        S V                  T ++   P+     K   +  PA KK          D DD+V+          + S P+    K   ++E     L+  
Subjt:  SLVCSVSFTLHIGINLNDFHFTANN---PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAI

Query:  SVMETEVPQVQAAKKKEPSKRA----------AAKKKTTAKSAQI-SASDDDE
        S  E++    Q +  + P KR+          A KK TT+KS  I   S DDE
Subjt:  SVMETEVPQVQAAKKKEPSKRA----------AAKKKTTAKSAQI-SASDDDE

Q64399 DNA topoisomerase 2-beta

0.0e+00

51.02

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Query:  KKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYEND-KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        KK  L+ SN      N +  K ++E +YQKK+QLEHILLRPDTY+GS+E  TQ +WVY+ D  M  R +++VPGLYKIFDEILVNAADNKQRD +M  +K
Subjt:  KKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYEND-KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPII
        V+ID E N IS++NNG G+PV  H+ EKVYVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFST+F +ETA  +    +KQ + +NM K SE  I
Subjt:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPII

Query:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS
         K  +G+++T +TF+PDLAKF M  L+ D+VALM +R  DLAG   K VKV  NG+++PV  F+ YVDLY+K          K  H   NERW++ +TLS
Subjt:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS

Query:  EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNDTD
        E  FQQ+SFVN I+T KGG HVDY+ +Q+   ++ VV KKNK   +VK   VK+++WVFIN LI+NP+FDSQTKE +T +P SFGS C+L+ +F K  ++
Subjt:  EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNDTD

Query:  CCKYCNPVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNV
        C           GI++S+L+WV FK    L KK    K  KI GI KL+DAN AGGK+S +CTLILTEGDSAK+LA++GLGV+GRD YGVFPLRGK+LNV
Subjt:  CCKYCNPVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNV

Query:  REASSKQITENKEIQYIKQILGLQQGKEYSNA---KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYT
        REAS KQI EN EI  I +I+GLQ  K Y +A   K LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLL+   FL EFITPIVKA+ +N   LSFY+
Subjt:  REASSKQITENKEIQYIKQILGLQQGKEYSNA---KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYT

Query:  MPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHLDQTG-
        +PE++ W++ +  N   W IKYYKGLGTST+KE +EYF  + +H+  F +    D  AI LAFSKKKI+DRK WL  F            P   L  T  
Subjt:  MPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHLDQTG-

Query:  RLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQF
        + + Y+DF+NKELILFS +D +RSIPS+VDG KPGQRK+LF  FKRN  +E KV+Q +G V+E SAYHHGEQ+L  TI+ +AQ+FVGSNNINLL P GQF
Subjt:  RLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQF

Query:  GTRNHGGKDHASSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNV
        GTR HGGKD AS RYI+T LS++ R L              F     ++  FL  +N+      Y+PIIP VL+NG+EGIGTGW+  +PNY+ R+I+ NV
Subjt:  GTRNHGGKDHASSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNV

Query:  RRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKD-FLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDD
        RRMLDG    PM P Y+ F GTI++     G   Y VSG I  V   T+ I ELPVR WT  YK+  L+ +      +  DK  A     I     +  D
Subjt:  RRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKD-FLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVV
          V   V +TEE +  A   GL K FKL TT++ ++M LFD  G +KKY+T + IL+EFF LRL +Y  RK      L+  L  E  KL N+ RFIL  +
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVV

Query:  NGEIIVSNRRKVDLFHELQAKGFTPFPKKT-KSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKAT
         G+I + NR K DL   L  +G+   P +  K A+ + A   +  ++ ++S          D+ Y+L M++ +LT EKV+EL   RD    EV+DL++ +
Subjt:  NGEIIVSNRRKVDLFHELQAKGFTPFPKKT-KSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKAT

Query:  PKSLWLNDLDSLEKELDEMDRNDAQ
        P  LW  DL +  +ELD+++  + +
Subjt:  PKSLWLNDLDSLEKELDEMDRNDAQ

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

2.9e-22

23.86

Show/hide

Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS
        GL+ +  EIL NA D  Q           IDV     + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS

Query:  TEF-VIETADGKRLKKYKQVFNDNMGKKSEPIIT-KC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP
            VI   DG    +++Q ++     + +P+ T  C        G   T + F PD   F      + + +A   + +  L   +  ++K E +     
Subjt:  TEF-VIETADGKRLKKYKQVFNDNMGKKSEPIIT-KC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP

Query:  VKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGISTIKGGTHVDYITNQIANYVMTVVNK-----------
        V S   Y     +  S   T+  K  H     R EI  +  +   Q          + + N I TI GGTH++ +   +   + ++  K           
Subjt:  VKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGISTIKGGTHVDYITNQIANYVMTVVNK-----------

Query:  -------------------------KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTK---RPNSFGSACELTPEFLKNDTDCCKYCNPVATKS
                                   K+ ++   +V+  L   ++  + NP F+ QTK  L     R     S  E   E+L+   D  +    + +KS
Subjt:  -------------------------KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTK---RPNSFGSACELTPEFLKNDTDCCKYCNPVATKS

Query:  GIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENK
          +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+
Subjt:  GIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENK

Query:  EIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWRESLRGNA
        EIQ +   LGL    E  N + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y     +    S  GNA
Subjt:  EIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWRESLRGNA

Query:  SGWSIKYYKGLG
        S ++I+ +KGLG
Subjt:  SGWSIKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

60.15

Show/hide

Query:  KRPLQNSNATNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNA NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ+LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNATNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV
        P+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  +TE P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN

Query:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL
                     KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLL
Subjt:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL

Query:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFY
        NVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY
Subjt:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFY

Query:  TMPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNK
        +MPEYE W+ESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNK
Subjt:  TMPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNK

Query:  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHA
        ELILFSMADLQRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD A
Subjt:  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHA

Query:  SSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLP
        S+RYI+TKLS VTR L              F      +  +L+++ +      YMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L+GE+M+P
Subjt:  SSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLP

Query:  MDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEE
        MDPWYRGF GTIEKTA+KEGG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    ++D+K V  D+ L+EE
Subjt:  MDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEE

Query:  NMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKV
        NML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++    N+E+ELLKLENK RFILAV++GEIIV+ R+K 
Subjt:  NMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKV

Query:  DLFHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERV-------SDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWL
        D+  +L+ KGFTPFP+K +S E  +AGA ++ D AEE  E++            S+Y+YLLAMAI +LTIEKV+EL  DRDK+   V D++K TPKSLWL
Subjt:  DLFHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERV-------SDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWL

Query:  NDLDSLEKELDEMDRNDAQAMEV--RKQQRDKSNIDLKPKISRNAPKAP---RNSKKTSNAETVPESMDTTSSSTTTESLV-----------CSVSFTLH
        +DL+SL+KEL+++D  DAQ  +     Q++ ++      K+ R APK P   + +KK S +ET   S     +      +V            S S T  
Subjt:  NDLDSLEKELDEMDRNDAQAMEV--RKQQRDKSNIDLKPKISRNAPKAP---RNSKKTSNAETVPESMDTTSSSTTTESLV-----------CSVSFTLH

Query:  IGINLNDFHFTANN--PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQA
           +  D   T NN   VVKPKG+       AKKK P   AA  + E+DE+L+L  RLA Y   S+P                                 
Subjt:  IGINLNDFHFTANN--PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQA

Query:  AKKKEPSKRAAAKKKTTAKSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAAAAKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPF
                   A    TA++++  A DDD+DD  + EVAP    K GGRK AA  K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPF
Subjt:  AKKKEPSKRAAAKKKTTAKSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAAAAKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPF

Query:  NKKSGSILGRTIGEEEEEAGNEDKVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDED
        NKKS S++ R    +EEE  + + V G++SSE +       +A  R QRANR ++ YV+SDS+++ +  S+FD+    ++D
Subjt:  NKKSGSILGRTIGEEEEEAGNEDKVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDED

AT3G23890.2 topoisomerase II

0.0e+00

60.5

Show/hide

Query:  KRPLQNSNATNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNA NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ+LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNATNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV
        P+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  +TE P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKN

Query:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL
                     KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLL
Subjt:  DTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL

Query:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFY
        NVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY
Subjt:  NVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFY

Query:  TMPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNK
        +MPEYE W+ESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNK
Subjt:  TMPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNK

Query:  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHA
        ELILFSMADLQRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD A
Subjt:  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHA

Query:  SSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLP
        S+RYI+TKLS VTR L              F      +  +L+++ +      YMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L+GE+M+P
Subjt:  SSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENK------YMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLP

Query:  MDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEE
        MDPWYRGF GTIEKTA+KEGG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    ++D+K V  D+ L+EE
Subjt:  MDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEE

Query:  NMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKV
        NML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++    N+E+ELLKLENK RFILAV++GEIIV+ R+K 
Subjt:  NMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKV

Query:  DLFHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERV-------SDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWL
        D+  +L+ KGFTPFP+K +S E  +AGA ++ D AEE  E++            S+Y+YLLAMAI +LTIEKV+EL  DRDK+   V D++K TPKSLWL
Subjt:  DLFHELQAKGFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERV-------SDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWL

Query:  NDLDSLEKELDEMDRNDAQAMEV--RKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANN
        +DL+SL+KEL+++D  DAQ  +     Q++ ++      K+ R APK P   K T  A          S S TTE+   ++               T NN
Subjt:  NDLDSLEKELDEMDRNDAQAMEV--RKQQRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANN

Query:  --PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKK
           VVKPKG+       AKKK P   AA  + E+DE+L+L  RLA Y   S+P                                            A  
Subjt:  --PVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLELKDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKK

Query:  KTTAKSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAAAAKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGE
          TA++++  A DDD+DD  + EVAP    K GGRK AA  K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPFNKKS S++ R    
Subjt:  KTTAKSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAAAAKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGE

Query:  EEEEAGNEDKVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDED
        +EEE  + + V G++SSE +       +A  R QRANR ++ YV+SDS+++ +  S+FD+    ++D
Subjt:  EEEEAGNEDKVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEASLDED

AT5G04130.1 DNA GYRASE B2

5.1e-27

24.06

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Query:  ATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNC
        +T         K    E  Q    L+ +  RP  Y+GS                         GL+ +  EIL NA D  Q   +    KV++ +     
Subjt:  ATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNC

Query:  ISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPIIT-KCK--
        +SV +NG G+P ++H   K    E +   L     +  T      +GG +G G  + N  S    +E +  +   ++KQ ++     + +PI T  C+  
Subjt:  ISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPIIT-KCK--

Query:  ----EGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTL
            +G   T + F PD   F      + + +A   + +  L   +  ++K E +       S   +     +  S   T+     H     R EI    
Subjt:  ----EGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTL

Query:  SEGQFQ---------QVSFVNGISTIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTK---RPNSF
         +   Q          + + N I TI GGTH++ +   +   + T+  K    K K+ ++   +V+  L   ++  + NP F+ QTK  L     R    
Subjt:  SEGQFQ---------QVSFVNGISTIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTK---RPNSF

Query:  GSACELTPEFLKNDTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVG
         S  E   EFL+   D  +    + +KS  +++  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     
Subjt:  GSACELTPEFLKNDTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVG

Query:  RDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVK
        R F  + PLRGK+LN+       + +N+EIQ +   LGL    E    + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K
Subjt:  RDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVK

Query:  ATHRNGTVLSFYTMPEYESWRESLRGNASGWSIKYYKGLG
           R       Y   + +    +   NAS ++I+ +KGLG
Subjt:  ATHRNGTVLSFYTMPEYESWRESLRGNASGWSIKYYKGLG

Sequences

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CDS sequence

Show/hide CDS sequence

ATGGCTGTGGAGAAGAAACGCCCACTGCAGAATAGCAACGCCACCAATGTCGACTCCAATCCGGCAGGTCCAAAGAAAACAATCGAAGAAATGTACCAGAAGAAGTCTCA
GCTCGAGCACATTCTCCTCAGGCCCGATACCTATGTCGGATCTATTGAAAAGCACACCCAAAGCCTCTGGGTTTACGAGAACGACAAAATGGTCCACCGATCCATCTCCT
ACGTGCCTGGTCTTTACAAGATCTTTGATGAAATTTTGGTCAATGCTGCTGATAATAAGCAGAGAGACCCTTCGATGGATTCAGTTAAGGTCAATATTGACGTCGAACAG
AACTGTATCAGTGTGTTCAACAACGGAGATGGAGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTGCCTGAGTTGATCTTTGGACATCTCTTGACTAGTAGTAA
CTATGATGACACTGAAAAGAAAACAACTGGTGGACGCAATGGCTATGGTGCGAAACTTACCAATATTTTTTCTACTGAATTTGTGATCGAGACAGCTGATGGAAAACGCC
TAAAGAAGTATAAGCAGGTATTCAATGATAACATGGGGAAAAAATCTGAGCCGATTATAACAAAGTGCAAGGAGGGTGATAATTGGACCAAGGTAACTTTTAAGCCAGAC
TTGGCAAAGTTCAACATGACTCATCTTGAAGATGATGTTGTTGCACTGATGAAGAAGAGAGTGTTGGATTTGGCTGGATGCCTTGGTAAAACCGTGAAGGTTGAGCTGAA
TGGACAAAGGGTCCCTGTTAAATCATTTCAAGATTATGTAGATCTCTACCTCAAATCAGCATCCACATTCCAGACGGAACCTCCAAAAAGGTATCACATTAAGCCTAATG
AGAGATGGGAAATTGTTGTGACCTTAAGTGAGGGCCAGTTCCAGCAGGTCAGCTTTGTGAACGGGATTTCAACTATTAAGGGTGGGACTCATGTTGATTACATCACTAAT
CAAATTGCAAATTATGTGATGACTGTTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCCCACAATGTGAAGAGCTATTTGTGGGTTTTTATCAATGCTCTCATTGA
TAATCCATCCTTCGACTCCCAAACCAAGGAAACTTTGACAAAACGTCCAAACAGTTTCGGTTCTGCATGCGAACTTACGCCGGAGTTTTTGAAGAATGATACTGATTGTT
GTAAATATTGCAACCCAGTGGCCACAAAATCTGGAATTATGGACAGCGTTCTCTCATGGGTTAATTTCAAGCAAAGCAAAGACCTAAAGAAAACAGATGGAGCAAAAACA
GAAAAGATTAGTGGTATAGAAAAGTTGGAGGATGCCAATTGCGCTGGAGGGAAGAACTCAGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCAGCTAAGGCCCTTGC
AATGGCTGGGCTCGGTGTAGTAGGGCGAGATTTTTATGGTGTATTCCCACTAAGAGGTAAATTGCTCAATGTGAGGGAAGCAAGTAGTAAACAGATCACAGAGAATAAAG
AAATTCAATACATCAAGCAAATTCTTGGACTTCAGCAAGGGAAGGAATACAGCAATGCTAAGGCTTTGAGATATGGTCATTTGATGATTATGACCGATCAGGATCATGAT
GGTTCGCACATTAAAGGACTCTTGATCAACTTTATTCATTCTTTCTGGCCTTCTCTCCTAAGAGTGCCGTCGTTTTTGGTTGAATTCATAACGCCTATTGTCAAGGCTAC
TCATAGGAATGGAACTGTTTTGTCATTCTATACCATGCCCGAGTATGAGTCTTGGAGAGAGAGCTTGAGAGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGT
TGGGAACAAGCACATCAAAAGAAGGAAGAGAGTACTTTGAACAGCTGACAAAGCACAAGAAAGATTTTATTTGGCAAGATGATAATGATGGGGAGGCCATTGAGCTTGCT
TTCAGTAAGAAGAAGATTGAAGATAGAAAGAATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGAAGATTGATAAAATACAGTGACTTCGTCAACAA
GGAGCTTATATTATTTTCCATGGCTGATTTACAAAGGTCTATTCCCTCAATGGTTGATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACT
TTATCAAAGAAGCAAAGGTTTCTCAATTTTCCGGTTACGTATCTGAGCACTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGAC
TTTGTCGGCAGTAACAACATTAATCTTCTTCTACCAAATGGACAGTTTGGCACACGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAACTTTC
AAATGTCACACGTCGATTGAACCTACCTGGTAAATCTCTTCCTGTCGTGTGCTTCTCTTCCTTTTCGCCACCACACTTTAGTGTATTTTTCTTCCTTTCTAAGGAAAATA
AGTATATGCCTATCATACCAACCGTTCTTGTCAATGGAAGTGAAGGAATTGGAACTGGGTGGAGTTCCTACGTTCCAAATTATAATCCTAGAGACATCATTAGAAATGTA
AGACGTATGTTGGATGGTGAAACGATGTTGCCAATGGATCCCTGGTATAGAGGTTTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGCACTAGTTACACTGT
TAGTGGAATTATAGAGGAAGTCAGTGATACGACGTTGAGAATAATTGAATTGCCAGTCCGCCGATGGACTAATGACTACAAGGACTTTCTTGACTCTGTCACAAGAGTTG
CTTCAAAGCATGACAAAGATAAAGAAAAAGCAGCGAAGGATCCTTTTATTGAGCAAGCTGATCACCACAGCGATGACAAAATTGTTTCCATTGATGTTCACTTGACGGAG
GAAAACATGTTATTGGCCATCCAGGAAGGTTTGAAGAAGAAATTCAAATTAACTACAACTGTCAGCACTAGCAACATGCACCTGTTTGATGCGAATGGCGTAATTAAGAA
ATATGACACCCCAGAACAGATTCTTGAGGAATTCTTCCCCCTTAGACTTGAATTCTACGAGAAAAGAAAGGTCAACATTCTTAGGAATCTTTTGGAAAACCTTGAAATGG
AGTTGCTTAAACTGGAAAACAAGGTGAGGTTTATCCTTGCTGTTGTGAATGGAGAAATAATAGTAAGCAATAGAAGAAAGGTTGATTTGTTCCATGAGCTTCAAGCGAAA
GGCTTTACACCCTTTCCAAAGAAGACTAAATCTGCTGAGCCGGAGGTTGCTGGGGCATCTAATGAAACAGATGAAGCAGAGGAGAGTCCGGAAGTAGTAAAAGGCGAACG
AGTTAGTGATTATGAGTATTTACTAGCTATGGCAATTGGAACCTTGACCATTGAGAAGGTTCAGGAGCTATGTAATGATAGAGACAAGCTGAAAGGGGAAGTGGACGATC
TGAGGAAGGCAACCCCCAAGTCTTTGTGGCTGAATGACCTTGATTCTCTTGAGAAAGAACTTGATGAGATGGATAGAAATGATGCTCAGGCAATGGAGGTAAGAAAACAG
CAGAGAGACAAATCAAATATCGATTTAAAGCCAAAAATCTCTAGAAATGCACCAAAAGCTCCACGTAACAGTAAGAAAACCAGCAATGCAGAAACTGTCCCAGAAAGTAT
GGACACAACATCTAGTTCTACAACAACGGAATCCCTTGTTTGTTCGGTTTCATTTACTTTGCATATTGGTATTAACCTCAATGATTTTCACTTCACAGCTAATAACCCGG
TGGTGAAGCCCAAAGGCAAAGCAGCTCCAAGAAAAGCTCCCGCTAAGAAGAAACAACCACAGGGTAAAGCTGCAGTTCTTGACGACGAGGACGACGAAGTCCTCGAGCTT
AAAGACCGTCTTGCAGCTTACAAAATCGAGTCATCTCCTGAACCATCAGAAGGTAAAATAATGTTCATTGTTGAAAATTTACTTCCAAGTTTGAACGCAATTTCAGTCAT
GGAAACTGAAGTGCCGCAAGTACAAGCAGCCAAGAAGAAAGAACCCAGCAAGAGAGCAGCTGCAAAGAAGAAAACTACTGCAAAGTCTGCTCAGATCTCTGCTAGTGATG
ACGACGAGGACGACTTCGAAATAAAGGAGGTAGCCCCTCCGGCAGCCAAGAAGGGAGGAGGAAGAAAGGCAGCTGCAAATGCCAAAACAACCAAGCCCCCTGCTGCAGCA
GCGAAGCTGGGGCAGAAACTGATAACTCAAATGCTGGAACCAGCAGAGAACTCCGGCATCTCACCGGAGAAGAAAGTGAGGAAGATCAGAGCATCACCTTTTAACAAGAA
AAGTGGCTCTATATTGGGAAGAACAATTGGGGAAGAGGAAGAAGAAGCTGGAAATGAAGATAAAGTAGTGGGTTCTGCTTCTTCTGAGACCACTGAAGAAGTTGCCAGAT
TTCCGGCGGCGAGAGGAAGATCACAGAGGGCAAACAGAACACAGGTCAGATATGTGGTTAGTGATTCAGATAATGATGTTTCTGAGGCTTCGGACTTTGATGAAGAAGCC
AGCCTTGATGAAGATTGA

mRNA sequence

Show/hide mRNA sequence

ATTGAACCCTAATTTCTATAAATTCTTTTTTCTCTCTCTCTCTTTCTTCATCTTGAATCTTTCAGACACCATCTCTGTGTCTTTTCCCTCTCTCAAGAACGAGTATTCCG
ATCGCCATGGCTGTGGAGAAGAAACGCCCACTGCAGAATAGCAACGCCACCAATGTCGACTCCAATCCGGCAGGTCCAAAGAAAACAATCGAAGAAATGTACCAGAAGAA
GTCTCAGCTCGAGCACATTCTCCTCAGGCCCGATACCTATGTCGGATCTATTGAAAAGCACACCCAAAGCCTCTGGGTTTACGAGAACGACAAAATGGTCCACCGATCCA
TCTCCTACGTGCCTGGTCTTTACAAGATCTTTGATGAAATTTTGGTCAATGCTGCTGATAATAAGCAGAGAGACCCTTCGATGGATTCAGTTAAGGTCAATATTGACGTC
GAACAGAACTGTATCAGTGTGTTCAACAACGGAGATGGAGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTGCCTGAGTTGATCTTTGGACATCTCTTGACTAG
TAGTAACTATGATGACACTGAAAAGAAAACAACTGGTGGACGCAATGGCTATGGTGCGAAACTTACCAATATTTTTTCTACTGAATTTGTGATCGAGACAGCTGATGGAA
AACGCCTAAAGAAGTATAAGCAGGTATTCAATGATAACATGGGGAAAAAATCTGAGCCGATTATAACAAAGTGCAAGGAGGGTGATAATTGGACCAAGGTAACTTTTAAG
CCAGACTTGGCAAAGTTCAACATGACTCATCTTGAAGATGATGTTGTTGCACTGATGAAGAAGAGAGTGTTGGATTTGGCTGGATGCCTTGGTAAAACCGTGAAGGTTGA
GCTGAATGGACAAAGGGTCCCTGTTAAATCATTTCAAGATTATGTAGATCTCTACCTCAAATCAGCATCCACATTCCAGACGGAACCTCCAAAAAGGTATCACATTAAGC
CTAATGAGAGATGGGAAATTGTTGTGACCTTAAGTGAGGGCCAGTTCCAGCAGGTCAGCTTTGTGAACGGGATTTCAACTATTAAGGGTGGGACTCATGTTGATTACATC
ACTAATCAAATTGCAAATTATGTGATGACTGTTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCCCACAATGTGAAGAGCTATTTGTGGGTTTTTATCAATGCTCT
CATTGATAATCCATCCTTCGACTCCCAAACCAAGGAAACTTTGACAAAACGTCCAAACAGTTTCGGTTCTGCATGCGAACTTACGCCGGAGTTTTTGAAGAATGATACTG
ATTGTTGTAAATATTGCAACCCAGTGGCCACAAAATCTGGAATTATGGACAGCGTTCTCTCATGGGTTAATTTCAAGCAAAGCAAAGACCTAAAGAAAACAGATGGAGCA
AAAACAGAAAAGATTAGTGGTATAGAAAAGTTGGAGGATGCCAATTGCGCTGGAGGGAAGAACTCAGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCAGCTAAGGC
CCTTGCAATGGCTGGGCTCGGTGTAGTAGGGCGAGATTTTTATGGTGTATTCCCACTAAGAGGTAAATTGCTCAATGTGAGGGAAGCAAGTAGTAAACAGATCACAGAGA
ATAAAGAAATTCAATACATCAAGCAAATTCTTGGACTTCAGCAAGGGAAGGAATACAGCAATGCTAAGGCTTTGAGATATGGTCATTTGATGATTATGACCGATCAGGAT
CATGATGGTTCGCACATTAAAGGACTCTTGATCAACTTTATTCATTCTTTCTGGCCTTCTCTCCTAAGAGTGCCGTCGTTTTTGGTTGAATTCATAACGCCTATTGTCAA
GGCTACTCATAGGAATGGAACTGTTTTGTCATTCTATACCATGCCCGAGTATGAGTCTTGGAGAGAGAGCTTGAGAGGCAATGCAAGTGGCTGGTCAATCAAGTACTATA
AGGGGTTGGGAACAAGCACATCAAAAGAAGGAAGAGAGTACTTTGAACAGCTGACAAAGCACAAGAAAGATTTTATTTGGCAAGATGATAATGATGGGGAGGCCATTGAG
CTTGCTTTCAGTAAGAAGAAGATTGAAGATAGAAAGAATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGAAGATTGATAAAATACAGTGACTTCGT
CAACAAGGAGCTTATATTATTTTCCATGGCTGATTTACAAAGGTCTATTCCCTCAATGGTTGATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGA
GGAACTTTATCAAAGAAGCAAAGGTTTCTCAATTTTCCGGTTACGTATCTGAGCACTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCA
CAGGACTTTGTCGGCAGTAACAACATTAATCTTCTTCTACCAAATGGACAGTTTGGCACACGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAA
ACTTTCAAATGTCACACGTCGATTGAACCTACCTGGTAAATCTCTTCCTGTCGTGTGCTTCTCTTCCTTTTCGCCACCACACTTTAGTGTATTTTTCTTCCTTTCTAAGG
AAAATAAGTATATGCCTATCATACCAACCGTTCTTGTCAATGGAAGTGAAGGAATTGGAACTGGGTGGAGTTCCTACGTTCCAAATTATAATCCTAGAGACATCATTAGA
AATGTAAGACGTATGTTGGATGGTGAAACGATGTTGCCAATGGATCCCTGGTATAGAGGTTTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGCACTAGTTA
CACTGTTAGTGGAATTATAGAGGAAGTCAGTGATACGACGTTGAGAATAATTGAATTGCCAGTCCGCCGATGGACTAATGACTACAAGGACTTTCTTGACTCTGTCACAA
GAGTTGCTTCAAAGCATGACAAAGATAAAGAAAAAGCAGCGAAGGATCCTTTTATTGAGCAAGCTGATCACCACAGCGATGACAAAATTGTTTCCATTGATGTTCACTTG
ACGGAGGAAAACATGTTATTGGCCATCCAGGAAGGTTTGAAGAAGAAATTCAAATTAACTACAACTGTCAGCACTAGCAACATGCACCTGTTTGATGCGAATGGCGTAAT
TAAGAAATATGACACCCCAGAACAGATTCTTGAGGAATTCTTCCCCCTTAGACTTGAATTCTACGAGAAAAGAAAGGTCAACATTCTTAGGAATCTTTTGGAAAACCTTG
AAATGGAGTTGCTTAAACTGGAAAACAAGGTGAGGTTTATCCTTGCTGTTGTGAATGGAGAAATAATAGTAAGCAATAGAAGAAAGGTTGATTTGTTCCATGAGCTTCAA
GCGAAAGGCTTTACACCCTTTCCAAAGAAGACTAAATCTGCTGAGCCGGAGGTTGCTGGGGCATCTAATGAAACAGATGAAGCAGAGGAGAGTCCGGAAGTAGTAAAAGG
CGAACGAGTTAGTGATTATGAGTATTTACTAGCTATGGCAATTGGAACCTTGACCATTGAGAAGGTTCAGGAGCTATGTAATGATAGAGACAAGCTGAAAGGGGAAGTGG
ACGATCTGAGGAAGGCAACCCCCAAGTCTTTGTGGCTGAATGACCTTGATTCTCTTGAGAAAGAACTTGATGAGATGGATAGAAATGATGCTCAGGCAATGGAGGTAAGA
AAACAGCAGAGAGACAAATCAAATATCGATTTAAAGCCAAAAATCTCTAGAAATGCACCAAAAGCTCCACGTAACAGTAAGAAAACCAGCAATGCAGAAACTGTCCCAGA
AAGTATGGACACAACATCTAGTTCTACAACAACGGAATCCCTTGTTTGTTCGGTTTCATTTACTTTGCATATTGGTATTAACCTCAATGATTTTCACTTCACAGCTAATA
ACCCGGTGGTGAAGCCCAAAGGCAAAGCAGCTCCAAGAAAAGCTCCCGCTAAGAAGAAACAACCACAGGGTAAAGCTGCAGTTCTTGACGACGAGGACGACGAAGTCCTC
GAGCTTAAAGACCGTCTTGCAGCTTACAAAATCGAGTCATCTCCTGAACCATCAGAAGGTAAAATAATGTTCATTGTTGAAAATTTACTTCCAAGTTTGAACGCAATTTC
AGTCATGGAAACTGAAGTGCCGCAAGTACAAGCAGCCAAGAAGAAAGAACCCAGCAAGAGAGCAGCTGCAAAGAAGAAAACTACTGCAAAGTCTGCTCAGATCTCTGCTA
GTGATGACGACGAGGACGACTTCGAAATAAAGGAGGTAGCCCCTCCGGCAGCCAAGAAGGGAGGAGGAAGAAAGGCAGCTGCAAATGCCAAAACAACCAAGCCCCCTGCT
GCAGCAGCGAAGCTGGGGCAGAAACTGATAACTCAAATGCTGGAACCAGCAGAGAACTCCGGCATCTCACCGGAGAAGAAAGTGAGGAAGATCAGAGCATCACCTTTTAA
CAAGAAAAGTGGCTCTATATTGGGAAGAACAATTGGGGAAGAGGAAGAAGAAGCTGGAAATGAAGATAAAGTAGTGGGTTCTGCTTCTTCTGAGACCACTGAAGAAGTTG
CCAGATTTCCGGCGGCGAGAGGAAGATCACAGAGGGCAAACAGAACACAGGTCAGATATGTGGTTAGTGATTCAGATAATGATGTTTCTGAGGCTTCGGACTTTGATGAA
GAAGCCAGCCTTGATGAAGATTGATTGAAGATATCTCCTTTGTATAGACAACTTATTTCCGGTGAGAAATTGATCTTCTTGGTGTAGTATTCGTGTTTGTAAGCAGTATA
AATTAGGAAGTTAAATGCTGCTCAGTGCTCAGTGTCCATACTTAATCAAAGATTTGGGCCGTGAAATTTGTACGGATTACCTAAAAATTAGGCTAAAAATGTCAAATGAC
CCCGATTTTAAAAAAAATGTCAATTGACCATGCTGACGTAAATTCAAATGAAATTATTAAAATGAACTCACACATGCAGAAAAGCAAATCTCACTTTTGCTCTTGTTATT
CTCGCTCTAGCTCTTCCTTTTTTCACTCTCATCTCGCTCTCTCTCACCTGAGATGGTCGTATCAAAGTTGCTTTTATTCTACCGGAGAAGAAGAAGAAACTGCAGAAGAA
GAAG

Protein sequence

Show/hide protein sequence

MAVEKKRPLQNSNATNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQSLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQ
NCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFNDNMGKKSEPIITKCKEGDNWTKVTFKPD
LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITN
QIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNDTDCCKYCNPVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT
EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHD
GSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWRESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELA
FSKKKIEDRKNWLRQFEPGTHLDQTGRLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQD
FVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRRLNLPGKSLPVVCFSSFSPPHFSVFFFLSKENKYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNV
RRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTE
ENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKVNILRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRKVDLFHELQAK
GFTPFPKKTKSAEPEVAGASNETDEAEESPEVVKGERVSDYEYLLAMAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEMDRNDAQAMEVRKQ
QRDKSNIDLKPKISRNAPKAPRNSKKTSNAETVPESMDTTSSSTTTESLVCSVSFTLHIGINLNDFHFTANNPVVKPKGKAAPRKAPAKKKQPQGKAAVLDDEDDEVLEL
KDRLAAYKIESSPEPSEGKIMFIVENLLPSLNAISVMETEVPQVQAAKKKEPSKRAAAKKKTTAKSAQISASDDDEDDFEIKEVAPPAAKKGGGRKAAANAKTTKPPAAA
AKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEAGNEDKVVGSASSETTEEVARFPAARGRSQRANRTQVRYVVSDSDNDVSEASDFDEEA
SLDED

Lsi03G012010 (gene) of Bottle gourd (USVL1VR-Ls) v1 genome