CuGenDBv2

Gene ID	Lsi05G001390
Organism	Lagenaria siceraria USVL1VR-Ls (Bottle gourd (USVL1VR-Ls) v1)
Description	3-hydroxybutyryl-CoA dehydrogenase
Genome location	chr05:2055082..2057813
RNA-Seq Expression	Lsi05G001390
Synteny	Lsi05G001390
Gene Ontology terms	GO:0006631 - fatty acid metabolic process (biological process) GO:0004300 - enoyl-CoA hydratase activity (molecular function) GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (molecular function) GO:0070403 - NAD+ binding (molecular function)
InterPro domains	IPR006108 - 3-hydroxyacyl-CoA dehydrogenase, C-terminal IPR006176 - 3-hydroxyacyl-CoA dehydrogenase, NAD binding IPR006180 - 3-hydroxyacyl-CoA dehydrogenase, conserved site IPR008927 - 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily IPR013328 - 6-phosphogluconate dehydrogenase, domain 2 IPR022694 - 3-hydroxyacyl-CoA dehydrogenase IPR036291 - NAD(P)-binding domain superfamily

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

TYK11243.1 3-hydroxybutyryl-CoA dehydrogenase [Cucumis melo var. makuwa]

1.7e-140

90.88

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAATHGH+VWLIDSDPAALAKA+DSISSSIQRLVS+NLLSRE+G IALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF+ELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEIVRGADTSN+TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFF LYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK P   KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

XP_004146246.1 uncharacterized protein LOC101221475 isoform X1 [Cucumis sativus]

1.6e-138

89.86

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAAT+GH+VWLIDSD AALAKA+DSISSSIQRLVS+NLLSRE+G  ALQRLKFSTDLKELHSADVIIEAI+ESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF+ELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEIVRGADTSN+TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKR IGVYDYRKLP+  KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

XP_008456022.1 PREDICTED: 3-hydroxybutyryl-CoA dehydrogenase [Cucumis melo]

1.9e-139

90.2

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAATHGH+VWLIDSDPAALAKA+DSISSSIQRLVS+NLLSRE+G IALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF+ELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEIVRGADTS++TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFF LYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQY DAGRLGRKRGIGVYDYRK P   KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

XP_023553026.1 uncharacterized protein LOC111810545 [Cucurbita pepo subsp. pepo]

5.9e-133

86.15

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIK IGVVGGGQMGSGIAQLAA +GH+VWLIDSDPAAL KA++SISSSIQRLVS+NLLSREVGV ALQRLK STDLKELHSADVIIEAIVESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LFLELDKIAK S+ILASNTSSIPITRLAS+TTRPD              +LVEIVRGADTS++TF AIK LAERLGKT+ICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFFALYTGVATKEDIDTGMKLGTNHPMGPLELAD IGLDVC+SIMKVLHSGLGD+KYAPCPLLVQYVDAGRLGRKRG+G+YDYRKLP+  KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

XP_038878166.1 3-hydroxybutyryl-CoA dehydrogenase [Benincasa hispida]

1.7e-140

91.22

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRL+SKNLLSREVGV ALQRLKFSTDLKELHSADVIIEAIVE EDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LFLELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEI+RGADTS++TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFF LYTGVATKEDID GMKLGTN+PMGPLELADFIGLDVCLSIMKVLH GLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQS KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L6N5 Uncharacterized protein

7.8e-139

89.86

Show/hide

Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAAT+GH+VWLIDSD AALAKA+DSISSSIQRLVS+NLLSRE+G  ALQRLKFSTDLKELHSADVIIEAI+ESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF+ELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEIVRGADTSN+TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKR IGVYDYRKLP+  KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

A0A1S3C2Y7 3-hydroxybutyryl-CoA dehydrogenase

9.2e-140

90.2

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAATHGH+VWLIDSDPAALAKA+DSISSSIQRLVS+NLLSRE+G IALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF+ELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEIVRGADTS++TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFF LYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQY DAGRLGRKRGIGVYDYRK P   KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

A0A5A7USC9 3-hydroxybutyryl-CoA dehydrogenase

9.2e-140

90.2

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAATHGH+VWLIDSDPAALAKA+DSISSSIQRLVS+NLLSRE+G IALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF+ELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEIVRGADTS++TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFF LYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQY DAGRLGRKRGIGVYDYRK P   KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

A0A5D3CH80 3-hydroxybutyryl-CoA dehydrogenase

8.3e-141

90.88

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        MTEIKAIGVVGGGQMGSGIAQLAATHGH+VWLIDSDPAALAKA+DSISSSIQRLVS+NLLSRE+G IALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF+ELDKIAKRSSILASNTSSIPITRLASATTRP+Q              LVEIVRGADTSN+TFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        AFF LYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK P   KSKSRL
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

A0A6J1CM78 uncharacterized protein LOC111012899

6.4e-133

87.07

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Query:  EIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLF
        EI+ IGVVGGGQMGSGIAQLAATHG +VWLIDSDPAALAKA++SIS+SIQRLVSKNLLS+EV V ALQRLKFSTDLKELHSADV+IEAIVESEDVKR+LF
Subjt:  EIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLF

Query:  LELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAF
        LELDKI KRS ILASNTSSIPITRLASATTRP Q              LVEIVRGADTSN+TFDAIK LAERLGKTVICSQDYSGFIVNRIL+PMINEAF
Subjt:  LELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAF

Query:  FALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL
        FALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGD KYAPCPLLVQYVDAGRLGRKRGIGVYDYRK+ Q  KS SRL
Subjt:  FALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

SwissProt top hits

e value

%identity

Alignment

P45856 Probable 3-hydroxybutyryl-CoA dehydrogenase

6.5e-66

49.12

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Query:  EIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLF
        EIK I V G GQMGSGIAQ AA  G  V + D +P A       +   + R   K   +       + R+  S  L+E   AD++IEAI E+   K ++F
Subjt:  EIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLF

Query:  LELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAF
          LD+I    +ILASNTSS+PIT +A+ T RP               +LVE++RG  TS +T   +  LAE++GKT +   D+ GF+ NR+L+PMINEA 
Subjt:  LELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAF

Query:  FALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK
        + +Y GVA  E ID  MKLG NHPMGPL LADFIGLD CLSIM+VLHSGLGD+KY PCPLL +YV AG LG+K G G YDY +
Subjt:  FALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK

P52041 3-hydroxybutyryl-CoA dehydrogenase

7.9e-64

48.94

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Query:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL
        +K + V+G G MGSGIAQ  A  G EV L D     + +  D I+ ++ +LV K  +     V  L R+  + DL      D++IEA VE  D+K+++F 
Subjt:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL

Query:  ELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF
        +LD I K  +ILASNTSS+ IT +ASAT RPD              +LVE++RG  TS +TFDA+K  +  +GK  +   +  GF+VNRIL+PMINEA  
Subjt:  ELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF

Query:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK
         L  G+A+ EDID  MKLG NHPMGPLEL DFIGLD+CL+IM VL+S  GD+KY P  LL +YV AG LGRK G G YDY K
Subjt:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK

P77851 3-hydroxybutyryl-CoA dehydrogenase

4.1e-60

46.26

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Query:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL
        ++ I V+G G MGSGIAQ+ A +G EV L D D   + K   +I  ++QR V K  ++ +     L R++ +T+L++   AD ++EA +E+ D+K+++F 
Subjt:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL

Query:  ELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF
        ELD+I K  +ILASNTSS+ IT +ASAT RP+              +LVE+++G  TS +TF+ ++ LA ++ KT I  ++  GF+VNRIL+PMINEA  
Subjt:  ELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF

Query:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYR
         L  GVAT EDID  MKLG NHP+GPL L+D IG DV L+IM VL+   GD+KY P PLL + V  G LGRK G G ++Y+
Subjt:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYR

Q45223 3-hydroxybutyryl-CoA dehydrogenase

2.3e-71

52.31

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Query:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL
        IK +GV+G GQMG+GIA +AA  G +V L D     L     +I+ ++ R VSK +++ E    AL R+  +  L +L   D++IE  VE E+VKRK+F 
Subjt:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL

Query:  ELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF
        EL  + K  +I+AS+TSSI ITRLA+AT RP+              +LVE++RG  T + TF+A K    +LGK V  S+D+  FIVNRIL+PMINEA +
Subjt:  ELDKIAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF

Query:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYR
         LY GV   E ID  MKLG +HPMGPLELADFIGLD CLSIM+VLH GL D+KY PCPLLV+YV+AG LGRK   G YDYR
Subjt:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYR

Q9RVG1 Probable 3-hydroxybutyryl-CoA dehydrogenase

1.4e-63

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Query:  GVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFLELDK
        GV+G GQMG GIAQ+AA  G +V + D     L +    I  S+ +L  K  L+ +     L R+ F+TDL++    D+++EAIVE++ +K  LF +L +
Subjt:  GVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFLELDK

Query:  IAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFFALYT
        I K   ILASNTSSIPIT LA+A+ RP               QLVE++RG  TS++T   +   AE+LGKT +   D+ GF+ NRILMPM+NEA   +  
Subjt:  IAKRSSILASNTSSIPITRLASATTRPD--------------QLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFFALYT

Query:  GVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDY
        GVA  E ID  MKLG NHPMGPL LADFIGLD CL+IM+VLH GLGD+KY P PLL + V AG LGRK G G Y Y
Subjt:  GVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDY

Arabidopsis top hits

e value

%identity

Alignment

AT3G06860.1 multifunctional protein 2

3.7e-24

29.02

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Query:  EIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLF
        +IK + ++GGG MGSGIA       + V L + +   L      + +++Q  V K  +S+E     +  LK S D +     D++IEA++E+  +K+++F
Subjt:  EIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLF

Query:  LELDKIAKRSSILASNTSSIPITRLASATTRPDQLV--------------EIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAF
         +L+K   +  ILASNTS+I + ++   T   D++V              EIVR   TS +    +  + +++ KT +   + +GF VNR+  P    A 
Subjt:  LELDKIAKRSSILASNTSSIPITRLASATTRPDQLV--------------EIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAF

Query:  FALYTGVATKEDIDTGM-KLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAP--CPLLVQYVDAGRLGRKRGIGVYDYRK
        F +  G A    ID  + K G   PMGP  L D +G  V ++          +  Y     PL+ +   AG   RK G  +YD ++
Subjt:  FALYTGVATKEDIDTGM-KLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAP--CPLLVQYVDAGRLGRKRGIGVYDYRK

AT3G15290.1 3-hydroxyacyl-CoA dehydrogenase family protein

3.1e-111

69.62

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Query:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK
        M E+K++GVVG GQMGSGIAQLAAT G +VWL+D+D  AL++A+ +ISSS++R VSK L+S+EVG  A+ RL+ +++L++L SAD+I+EAIVESED+K+K
Subjt:  MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRK

Query:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE
        LF +LD IAK S+ILASNTSSI ITRLASAT RP Q              LVEI+RGADTS +TF A K+LAER GKT +CSQDY+GF+VNRILMPMINE
Subjt:  LFLELDKIAKRSSILASNTSSIPITRLASATTRPDQ--------------LVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINE

Query:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSK
        AF  LYTGVATKEDID+GMK GTNHPMGPLELAD IGLDVCLS+MKVLH GLGD+KYAPCPLLVQYVDAGRLGRKRG+GVYDYR+  Q +  +
Subjt:  AFFALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSK

AT4G29010.1 Enoyl-CoA hydratase/isomerase family

4.8e-24

28.72

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Query:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL
        IK + V+GGG MGSGIA         V L + +   L K   S+ ++++ LVS+  L+++    AL   K   D  E +  D++IEA++E+  +K+ +F 
Subjt:  IKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFL

Query:  ELDKIAKRSSILASNTSSIPITRLASATTRPDQLV--------------EIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF
        E++K+     ILASNTS+I +  +   T   D++V              EIVR  +TS +    +  + + + K  +   +  GF VNR   P    A  
Subjt:  ELDKIAKRSSILASNTSSIPITRLASATTRPDQLV--------------EIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFF

Query:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK
            GV            G   P+GP +L D  G  + L++  +     GD  +   P+    + +GR G+  G G Y Y K
Subjt:  ALYTGVATKEDIDTGMKLGTNHPMGPLELADFIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRK

Sequences

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CDS sequence

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ATGACGGAAATCAAGGCCATTGGAGTCGTCGGAGGCGGTCAAATGGGATCCGGAATTGCCCAACTCGCCGCCACACACGGCCATGAAGTTTGGCTAATTGATTCAGACCC
TGCCGCTCTTGCTAAAGCATCCGACTCCATTTCTTCCTCAATCCAACGCCTGGTCTCTAAAAACCTTCTCTCTCGAGAAGTTGGTGTCATTGCTCTTCAACGTCTTAAGT
TTTCAACTGATTTGAAAGAGCTTCATTCAGCAGATGTCATCATCGAAGCTATCGTGGAATCAGAAGATGTTAAAAGAAAGCTATTTCTTGAATTAGATAAGATTGCAAAA
CGGTCTTCCATTCTAGCTTCTAATACAAGTTCCATCCCGATTACTCGCTTAGCATCAGCAACCACACGTCCTGACCAGTTGGTTGAGATTGTTCGAGGTGCGGATACATC
CAATAAAACATTTGATGCCATAAAAATCTTGGCTGAGAGGCTTGGCAAAACAGTGATATGTTCTCAGGACTACTCTGGCTTCATAGTGAACAGAATCCTAATGCCAATGA
TTAACGAGGCGTTTTTTGCTCTCTACACGGGAGTGGCAACGAAGGAAGACATTGACACGGGAATGAAGCTAGGAACAAATCATCCTATGGGTCCCTTGGAGCTCGCAGAC
TTCATTGGTTTGGATGTCTGTTTATCAATCATGAAGGTTCTCCACTCTGGACTTGGTGACAATAAATATGCTCCCTGCCCTCTTCTCGTGCAGTATGTTGATGCTGGTCG
CCTGGGAAGAAAGCGGGGAATAGGCGTATACGATTACCGTAAATTACCGCAATCGGTAAAATCCAAGTCCCGACTTTGA

mRNA sequence

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Protein sequence

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MTEIKAIGVVGGGQMGSGIAQLAATHGHEVWLIDSDPAALAKASDSISSSIQRLVSKNLLSREVGVIALQRLKFSTDLKELHSADVIIEAIVESEDVKRKLFLELDKIAK
RSSILASNTSSIPITRLASATTRPDQLVEIVRGADTSNKTFDAIKILAERLGKTVICSQDYSGFIVNRILMPMINEAFFALYTGVATKEDIDTGMKLGTNHPMGPLELAD
FIGLDVCLSIMKVLHSGLGDNKYAPCPLLVQYVDAGRLGRKRGIGVYDYRKLPQSVKSKSRL

Lsi05G001390 (gene) of Bottle gourd (USVL1VR-Ls) v1 genome