CuGenDBv2

Gene ID	Lsi05G004990
Organism	Lagenaria siceraria USVL1VR-Ls (Bottle gourd (USVL1VR-Ls) v1)
Description	coiled-coil domain-containing protein 22
Genome location	chr05:6275593..6279549
RNA-Seq Expression	Lsi05G004990
Synteny	Lsi05G004990
Gene Ontology terms	GO:2000060 - positive regulation of ubiquitin-dependent protein catabolic process (biological process) GO:0097602 - cullin family protein binding (molecular function)
InterPro domains	IPR008530 - Coiled-coil domain-containing protein 22

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0065733.1 coiled-coil domain-containing protein 22 [Cucumis melo var. makuwa]

1.4e-223

79.59

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKS VSIPPD+SSIRNL+PP+ FSICAQVLN++HPQTK P+STSLPDSVADQFK+C+EIASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGKSKVLEDGDGRKE KA+TS+ YYVE+Q  K DT+DSV THQKV++KLAD NIIAEET+S +SII RFSDFCL+++SLGEA MVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNAPKD SEV GNE+V LQGNNRHE  +YIQK  EDQ I P+EEV T A+EL+H QVELERL+AVT+IVFDDN  IEFHLQQLEEQINS+ L+LL MK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLE KRRSLQESLCA NP AQEKL+KLREFE EKKLIE EI+ REEENSN+  DLKKQPKQ SRRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELVLR                            EAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        ASASRSL+FNKLQADLDAIRRENS+LEQHLC K P+D+V
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

XP_004148284.1 coiled-coil domain-containing protein 22 isoform X1 [Cucumis sativus]

1.6e-227

81.63

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKSGVSIP D+SSIRNL+PP+ FSICAQVLNR+HPQTK P+STSLPDSVADQFK+ +EIASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGK KVLEDGDGRKETKADTSK YYVE+QS KIDT+DSV THQKVENKLADLNI+AEETKS +SI+ RFSDF L ++S GEAAMVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNA KDQSEVSGNE+V LQGNNRHE  +YIQK  EDQEI P+EEV T A+EL+H QVELERLKAVT IVFDDN  IEFHL+QLEEQINSR L+LL MK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLE KRRSLQESLCASNPKAQEKLQKLREFE EKKLIE EI+ REEENSN+A DLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELVLR                            EAKKD  GKQAHKLLT+IHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        ASASRSLNFNKLQADLDAIRREN +LEQHLC K  IDKV
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

XP_008449035.1 PREDICTED: coiled-coil domain-containing protein 22 [Cucumis melo]

9.6e-225

79.59

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKS VSIPPD+SSIRNL+PP+ FSICAQVLN++HPQTK P+STSLPDSVADQFK+C+ IASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGKSKVLEDGDGRKETKA+TS+ YYVE+Q  K DT+DSV THQKV++KLAD NIIAEET+S +SII RFSDFCL+++SLGEA MVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNAPKD SEV GNE+V LQGNNRHE  +YIQK  EDQ I P+EEV T A+EL+H QVELERL+AVT+IVFDDN  IEFHLQQLEEQINS+ L+LL MK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLE KRRSLQESLCA NP AQEKL+KLREFE EKKLIE EI+ REEENSN+  DLKKQPKQ SRRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELVLR                            EAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        ASASRSL+FNKLQADLDAIRRENS+LEQHLC K P+D+V
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

XP_038903177.1 coiled-coil domain-containing protein 22 isoform X1 [Benincasa hispida]

4.7e-240

85.37

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKSGVSIPPD+SSIRNLTPPLLFSICAQVLNR+H QTKIP+S SLPDSVADQFKIC+EIASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGKSKVLEDGDGRKETKADTSK YYVED S+K++T+DSVFTHQKVENK ADLNII+EETKSSNSI+GRFSD CLVQQSLGEAAM DNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNAPKDQSEVSGNE+VALQGNNRHE  SY +K CEDQEIRP+EEV +KA+ELEHLQVELERLKAVT+IVFD+N+ IEFHLQQLEEQINSRNLNL AMK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLENKR+SLQ+SLCASNPKAQEKLQKLREFE EKKLIESEI+ REEENSNLATD+KKQPKQL RRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELV                              EAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQK
        ASASRSLNF KLQADLDAIRRENSYLEQHLC K
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQK

XP_038903178.1 coiled-coil domain-containing protein 22 isoform X2 [Benincasa hispida]

7.3e-241

85.55

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKSGVSIPPD+SSIRNLTPPLLFSICAQVLNR+H QTKIP+S SLPDSVADQFKIC+EIASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGKSKVLEDGDGRKETKADTSK YYVED S+K++T+DSVFTHQKVENK ADLNII+EETKSSNSI+GRFSD CLVQQSLGEAAM DNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNAPKDQSEVSGNE+VALQGNNRHE  SY +K CEDQEIRP+EEV +KA+ELEHLQVELERLKAVT+IVFD+N+ IEFHLQQLEEQINSRNLNL AMK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLENKR+SLQ+SLCASNPKAQEKLQKLREFE EKKLIESEI+ REEENSNLATD+KKQPKQL RRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELV R                            EAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQK
        ASASRSLNF KLQADLDAIRRENSYLEQHLC K
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L4U9 Uncharacterized protein

7.7e-228

81.63

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKSGVSIP D+SSIRNL+PP+ FSICAQVLNR+HPQTK P+STSLPDSVADQFK+ +EIASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGK KVLEDGDGRKETKADTSK YYVE+QS KIDT+DSV THQKVENKLADLNI+AEETKS +SI+ RFSDF L ++S GEAAMVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNA KDQSEVSGNE+V LQGNNRHE  +YIQK  EDQEI P+EEV T A+EL+H QVELERLKAVT IVFDDN  IEFHL+QLEEQINSR L+LL MK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLE KRRSLQESLCASNPKAQEKLQKLREFE EKKLIE EI+ REEENSN+A DLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELVLR                            EAKKD  GKQAHKLLT+IHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        ASASRSLNFNKLQADLDAIRREN +LEQHLC K  IDKV
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

A0A1S3BKI6 coiled-coil domain-containing protein 22

4.6e-225

79.59

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKS VSIPPD+SSIRNL+PP+ FSICAQVLN++HPQTK P+STSLPDSVADQFK+C+ IASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGKSKVLEDGDGRKETKA+TS+ YYVE+Q  K DT+DSV THQKV++KLAD NIIAEET+S +SII RFSDFCL+++SLGEA MVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNAPKD SEV GNE+V LQGNNRHE  +YIQK  EDQ I P+EEV T A+EL+H QVELERL+AVT+IVFDDN  IEFHLQQLEEQINS+ L+LL MK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLE KRRSLQESLCA NP AQEKL+KLREFE EKKLIE EI+ REEENSN+  DLKKQPKQ SRRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELVLR                            EAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        ASASRSL+FNKLQADLDAIRRENS+LEQHLC K P+D+V
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

A0A5A7VC01 Coiled-coil domain-containing protein 22

6.7e-224

79.59

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKS VSIPPD+SSIRNL+PP+ FSICAQVLN++HPQTK P+STSLPDSVADQFK+C+EIASAIKDLGFIGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPEA+DGKSKVLEDGDGRKE KA+TS+ YYVE+Q  K DT+DSV THQKV++KLAD NIIAEET+S +SII RFSDFCL+++SLGEA MVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--
        VNAPKD SEV GNE+V LQGNNRHE  +YIQK  EDQ I P+EEV T A+EL+H QVELERL+AVT+IVFDDN  IEFHLQQLEEQINS+ L+LL MK  
Subjt:  VNAPKDQSEVSGNETVALQGNNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMK--

Query:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE
         DAERELLE KRRSLQESLCA NP AQEKL+KLREFE EKKLIE EI+ REEENSN+  DLKKQPKQ SRRSYINRVKEITKNSRKQDADIDRILKETRE
Subjt:  -DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRE

Query:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA
        LQLE NNIQERLHRTYAVVDELVLR                            EAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRL+RETAEYEKKIA
Subjt:  LQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIA

Query:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        ASASRSL+FNKLQADLDAIRRENS+LEQHLC K P+D+V
Subjt:  ASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

A0A6J1EW97 coiled-coil domain-containing protein 22 isoform X1

2.5e-223

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Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKSGVS+PPDVSSIRNLTPPLLFSICAQVLNR+H QT+IPY+TSLPDSVADQFKICTEIASAIKDLG+IGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPE +DGK+KVLED DGRKETK DT K +YV  QS+ IDT+DSVFTHQKVENKL+DLNIIAEETKSS+SI+GRFSD        GEAAMVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNN------RHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNL
        VNAPKDQSEVSGNE+VA+QGNN      RHE SSYIQK  EDQEIRP+EEV+TKA+ELEHL VELERLKA T IVFDDNR IE HLQ+LEEQI+SR LNL
Subjt:  VNAPKDQSEVSGNETVALQGNN------RHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNL

Query:  LAMKD---AERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRI
        LA K    AE+ELLENKRR+LQESLCASNPKAQEKLQKLREFELEK+LIESEI  REEEN NL+T+LKKQPKQ SRRSYI+RVKEITKNSRKQD DIDRI
Subjt:  LAMKD---AERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRI

Query:  LKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAE
        LKETRELQLE NNIQERLHRTYA+VDELVLR                            EAKK+GIGK+AHKLLTSIHENFGEISNKILSTDRL+RETAE
Subjt:  LKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAE

Query:  YEKKIAASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        YEKKIAASASRSL+FNKLQADLDAIRRENS LEQ+LC K PID++
Subjt:  YEKKIAASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

A0A6J1L5Y0 coiled-coil domain-containing protein 22 isoform X1

1.8e-221

79.63

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEESQEILLNSLQKSGVS+PPDVSSIR LTPPLLFSICAQVLNR+H QT+IPY+TSLPDSVADQFKICTEIASAIKDLG+IGD SFHKFLYPSEEDLYKL
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL
        IRFLVERLPE +DGKSKVLEDGDGRKETKADT K +YV  QS+ IDT DSVFTHQKVENKL+DLNIIAEETKSS+SI+GR SD        GE AMVDNL
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNL

Query:  VNAPKDQSEVSGNETVALQGNN------RHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNL
        VNAPK QSEVSGNE+VA+QGNN      RHE SSYIQK  EDQEIRP+EEV+TKA+ELEHL VELERLKA T IVFDDNR IE HLQ+LEEQI+SR LNL
Subjt:  VNAPKDQSEVSGNETVALQGNN------RHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNL

Query:  LAMK---DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRI
        LA K   DAE+ELLENKRR+LQESLCASNPKA EKLQKLREFELEK+LIESEI+ REE N NL+T+LKKQPKQ SRRSYI+RVKEITKNSRKQDADIDRI
Subjt:  LAMK---DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRI

Query:  LKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAE
        LKETRELQLE NNIQERLHRTYA+VDELVLR                            EAKK+GIGK+AHKLLTSIHENFGEISNKILSTDRL+RETAE
Subjt:  LKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAE

Query:  YEKKIAASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV
        YEKKIAASASRSL+FNKLQADLDAIR+ENS LEQ+LC K PID++
Subjt:  YEKKIAASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

SwissProt top hits

e value

%identity

Alignment

O60826 Coiled-coil domain-containing protein 22

6.8e-24

23.61

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Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEE+  IL++SL+++G ++PPDV ++R  T  L+     + L  ++P      S  LP +++ +F++   +A A  DLG+  +  +  FLYPSE DL  L
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLP----EAAD---GKSKVLEDGDGRK----------ETKADTSKFYYVEDQS--------------------------------------EKI
        + FL ERLP    E AD   G S +L    G +               T K  +++  +                                      + +
Subjt:  IRFLVERLP----EAAD---GKSKVLEDGDGRK----------ETKADTSKFYYVEDQS--------------------------------------EKI

Query:  DTNDSVFTHQKVE-------NKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNLVNAP---KDQSEV-----SGNETVALQGNNRHEDSSYI
            S+  H  ++       ++  D + +   ++       R     L +Q          L+ AP   +D  E+     +G +T A +G+       + 
Subjt:  DTNDSVFTHQKVE-------NKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNLVNAP---KDQSEV-----SGNETVALQGNNRHEDSSYI

Query:  QKICEDQEIRPVEEV------------ATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLN------LLAMKDAERELLENKRRSL
          +    +   V +V            A +  ELE L+ +LE +    + V  D + +     Q E +     L+       L +K    ELL +   +L
Subjt:  QKICEDQEIRPVEEV------------ATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLN------LLAMKDAERELLENKRRSL

Query:  QESLCASNPKAQ-----------------------EKLQKLREFELEKKLIE------------SEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEI
         +        AQ                        KLQ  RE E  ++L E             E + +EE    L ++L+  P+ +SR +Y  R+ EI
Subjt:  QESLCASNPKAQ-----------------------EKLQKLREFELEKKLIE------------SEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEI

Query:  TKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISN
          N RKQ  +I +IL +T+ELQ E N++  +L RT+AV DELV +                            +AKKD   ++A+K L ++HEN  ++  
Subjt:  TKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISN

Query:  KILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL
         I  T  + RE  + E++I     +    N  K++ D  A+R+EN+ L
Subjt:  KILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL

P86182 Coiled-coil domain-containing protein 22

3.1e-24

24.85

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Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEE+  IL++SL+++G ++PP+V ++R  T  L+     + L  ++P      S  LP +++ +F++   +A A  DLG+  +  +  FLYPSE DL  L
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFY-----YVEDQ-----------SEKIDTNDSVFTHQKVENK---LADLNIIAE--ETKSSNSIIG
        + FL ERLP  A       ED D   +   D++ F       + DQ           + K+         Q   +    L +LN   E  E ++S  ++ 
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFY-----YVEDQ-----------SEKIDTNDSVFTHQKVENK---LADLNIIAE--ETKSSNSIIG

Query:  RFSDFCLVQQSLGEAA--------MVDNLVN--APKDQSEVSGNETVALQGNNRHEDSSYIQKICE-----------DQEIRPVEEV-------------
          S    V Q LG AA         +   VN   P D+  V     +  Q + R       +++ E             ++R + E+             
Subjt:  RFSDFCLVQQSLGEAA--------MVDNLVN--APKDQSEVSGNETVALQGNNRHEDSSYIQKICE-----------DQEIRPVEEV-------------

Query:  -ATKATELEHLQVELE---RLKAVTKIVFDDNRP-------IEFHLQQLEEQINSRNLNL----------------------------------LAMKDA
          ++ T  E     LE   +   V  I     RP        E  L+ L EQ+ S N N+                                  L +K  
Subjt:  -ATKATELEHLQVELE---RLKAVTKIVFDDNRP-------IEFHLQQLEEQINSRNLNL----------------------------------LAMKDA

Query:  ERELLENKRRSLQESLCASNPKAQ-----------------------EKLQKLREFELEKKLIE------------SEIKMREEENSNLATDLKKQPKQL
          ELL +   +L +        AQ                        KLQ  RE E  ++L+E             E + +EE    L ++L+  PK +
Subjt:  ERELLENKRRSLQESLCASNPKAQ-----------------------EKLQKLREFELEKKLIE------------SEIKMREEENSNLATDLKKQPKQL

Query:  SRRSYINRVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLL
        SR +Y  R+ EI  N RKQ  +I +IL +T+ELQ E N++  +L RT+AV DELV +                            +AKKD   ++A+K L
Subjt:  SRRSYINRVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLL

Query:  TSIHENFGEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL
         ++HEN  ++   I  T  + RE  + E++I     +    N  K+  D  A+R+EN+ L
Subjt:  TSIHENFGEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL

Q28G12 Coiled-coil domain-containing protein 22

1.3e-22

22.66

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Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEE   IL++SL+  G  +P DV SIR     L+     + L  ++P      S  LP  ++ +F+I T +A A +DLG+ G+  +  FLY SE D+  L
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAAD-------GKSKVLEDGDG----------------------RKETKADTSKFYYVEDQSEKIDTNDSVFTHQK---------VENKLA
        + FL E+LP  +        GKS +L+                          R +      +F+          T  S+   +K         V ++L 
Subjt:  IRFLVERLPEAAD-------GKSKVLEDGDG----------------------RKETKADTSKFYYVEDQSEKIDTNDSVFTHQK---------VENKLA

Query:  DLNIIAEETKSSNS-----------------IIGRFS--DF---------CLVQQSLGEAA--MVDNLVNAPKDQSEVSGNETVALQGNNRHEDSS----
         L  +A      N+                 +  R S  D+           +Q+ L + A  + +N + +   Q      +   L G +  +  S    
Subjt:  DLNIIAEETKSSNS-----------------IIGRFS--DF---------CLVQQSLGEAA--MVDNLVNAPKDQSEVSGNETVALQGNNRHEDSS----

Query:  ---------------YIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLN------LLAMKDAERELL--
                        +Q+  E    +  ++   +  EL  LQ +++ ++   + + + N+ ++  + Q+E ++N    +      ++ +K    ELL  
Subjt:  ---------------YIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLN------LLAMKDAERELL--

Query:  -ENKRRSLQESLCASN--------------PKAQEKLQKLREFELE------------KKLIE------SEIKMREEENSNLATDLKKQPKQLSRRSYIN
         +N    LQ  + AS+               +  E+ ++L+  + E            K L E       E K +EE    L ++ +  PK++SR +Y  
Subjt:  -ENKRRSLQESLCASN--------------PKAQEKLQKLREFELE------------KKLIE------SEIKMREEENSNLATDLKKQPKQLSRRSYIN

Query:  RVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENF
        R+ EI  N +KQ  +I +IL +T+ELQ E NN+  ++ RT+ V DELV +                            +AKKD   ++A+K L ++HEN 
Subjt:  RVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENF

Query:  GEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL
         ++   I  T  + RE  + E++I    ++    N  K+  D  AI++EN+ L
Subjt:  GEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL

Q6PA15 Coiled-coil domain-containing protein 22

9.9e-23

22.21

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Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEE   IL++SL+  G  +P D+ SIR     L+     + L  ++P      S  LP  ++ QF+I T +A A +DLG+  +  +  FLY SE D+  L
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAAD-------GKSKVLE----------------------DGDGRKETKADTSKFY-----YVEDQSEKIDTNDSVFTHQK----VENKLA
        + FL E+LP  +        GKS +L+                          R ++     +F+        D + K   N+     Q+    V ++L 
Subjt:  IRFLVERLPEAAD-------GKSKVLE----------------------DGDGRKETKADTSKFY-----YVEDQSEKIDTNDSVFTHQK----VENKLA

Query:  DLNIIA-----------------EETKSSNSIIGRFS--DF---------CLVQQSLGEAA--MVDNLVNAPKDQSEVSGNETVALQGNNRHEDSS----
         L  +A                 E    S  +  R S  D+           +Q+ L + A  + +N + +   Q          L G +  +  S    
Subjt:  DLNIIA-----------------EETKSSNSIIGRFS--DF---------CLVQQSLGEAA--MVDNLVNAPKDQSEVSGNETVALQGNNRHEDSS----

Query:  ---------------YIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQIN------SRNLNLLAMKDAERELLEN
                        +Q+  E    +  ++   +  E+  LQ +++ ++   + + + N+ ++  + Q+E ++N          N++ +K    ELL +
Subjt:  ---------------YIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQIN------SRNLNLLAMKDAERELLEN

Query:  KRRSLQESLCASNPKAQEKLQKLREFELE-----------------------------KKLIE------SEIKMREEENSNLATDLKKQPKQLSRRSYIN
           +L +     +  AQ     + ++E                               K L E       E K +EE    L ++ +  PK++SR +Y  
Subjt:  KRRSLQESLCASNPKAQEKLQKLREFELE-----------------------------KKLIE------SEIKMREEENSNLATDLKKQPKQLSRRSYIN

Query:  RVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENF
        R+ EI  N +KQ  +I +IL +T+ELQ E NN+  ++ RT+ V DELV +                            +AKKD   ++A+K L ++HEN 
Subjt:  RVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENF

Query:  GEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL
         ++   I  T  + RE  + E++I    ++    N  K+  D  AI++EN+ L
Subjt:  GEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL

Q9JIG7 Coiled-coil domain-containing protein 22

8.9e-24

24.05

Show/hide

Query:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL
        MEE+  IL++SL+++G ++PP+V ++R  T  L+     + L  ++P      S  LP +++ +F++   +A A  DLG+  +  +  FLYPSE DL  L
Subjt:  MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKL

Query:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFY-----YVEDQ-----------SEKIDTNDSVFTHQKVENK---LADLNIIAE--ETKSSNSIIG
        + FL ERLP  A       ED D   +   D++ F       + DQ           + K+         Q   +    L +LN   E  E ++S  ++ 
Subjt:  IRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFY-----YVEDQ-----------SEKIDTNDSVFTHQKVENK---LADLNIIAE--ETKSSNSIIG

Query:  RFSDFCLVQ---QSLGE--AAMVDNLVN--APKDQSEVSGNETVALQGNNRHEDSSYIQKICE-----------DQEIRPVEEV----------------
          +    +Q    SL E  A+ +   VN   P D+  V     V  Q ++R       +++ E             ++R + E+                
Subjt:  RFSDFCLVQ---QSLGE--AAMVDNLVN--APKDQSEVSGNETVALQGNNRHEDSSYIQKICE-----------DQEIRPVEEV----------------

Query:  ------------------------------------ATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNL------LAMKDAERE
                                            A +  ELE L+ +L  +    + V  D + +  +L Q+E +     L++      L +K    E
Subjt:  ------------------------------------ATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNL------LAMKDAERE

Query:  LLENKRRSLQESLCASNPKAQ-----------------------EKLQKLREFELEKKLIE------------SEIKMREEENSNLATDLKKQPKQLSRR
        LL +   +L +        AQ                        +LQ  RE E  ++L E             E + +EE    L ++L+  PK +SR 
Subjt:  LLENKRRSLQESLCASNPKAQ-----------------------EKLQKLREFELEKKLIE------------SEIKMREEENSNLATDLKKQPKQLSRR

Query:  SYINRVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSI
        +Y  R+ EI  N RKQ  +I +IL +T+ELQ E N++  +L RT+AV DELV +                            +AKKD   ++A+K L ++
Subjt:  SYINRVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSI

Query:  HENFGEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL
        HEN  ++   I  T  + RE  + E++I     +    N  K+  D  A+R+EN+ L
Subjt:  HENFGEISNKILSTDRLKRETAEYEKKIAASASRSL--NFNKLQADLDAIRRENSYL

Arabidopsis top hits

e value

%identity

Alignment

AT1G55830.1 unknown protein

2.4e-64

39.25

Show/hide

Query:  KFLYPSEEDLYKLIRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTH--QKVENKLADLNIIAEETKSSNSIIGRFSDFC
        +FL+PSE+D Y+L+RFLVERL E ++G+ K L  GD     K +T  F  + D     +  D  F    QKVE  L DL + +E++ SS+S+        
Subjt:  KFLYPSEEDLYKLIRFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTH--QKVENKLADLNIIAEETKSSNSIIGRFSDFC

Query:  LVQQSLGEAAMVDNLVNAPKDQSEVSGNETVALQGNNRHEDSSYIQKI--------CEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIE
            +   +A VD   +   D         ++L+ ++R E++SY             ++Q    +EE+ + +++L  L+ ELE L+   + + DD +P  
Subjt:  LVQQSLGEAAMVDNLVNAPKDQSEVSGNETVALQGNNRHEDSSYIQKI--------CEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIE

Query:  FHLQQLEEQINSRNLNLLAMK---DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRV
         +L+QL +Q+  +  N++ +K   D  R  LE K+  L + L    P+A+EK  KLR+ EL+ + + SEI+ RE+E  NL  +L++QPK   R+SYI+ +
Subjt:  FHLQQLEEQINSRNLNLLAMK---DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRV

Query:  KEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGE
        KEITKNSRK D DI RI  ETRELQLE N+IQERLHR+YAVVDE+V R                            E KKD   +Q +KLLTSIH  F +
Subjt:  KEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGE

Query:  ISNKILSTDRLKRETAEYEKKIAASASRSLNFNKLQADLDAIRRENSYLEQ
        IS KIL TDR +RET +YEKK+ +  +R ++  KLQADLDAIR+EN  L++
Subjt:  ISNKILSTDRLKRETAEYEKKIAASASRSLNFNKLQADLDAIRRENSYLEQ

AT1G55830.2 unknown protein

5.6e-90

40.97

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Query:  EESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKLI
        EES++IL+ +L +SGVSIP D +S+   TP  L SICAQ+LN + P     +S  LPDS+ ++F+ICT+IA ++K+LG+I D S++KFL+PSE+D Y+L+
Subjt:  EESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKLI

Query:  RFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTH--QKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDN
        RFLVERL E ++G+ K L  GD     K +T  F  + D     +  D  F    QKVE  L DL + +E++ SS+S+            +   +A VD 
Subjt:  RFLVERLPEAADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTH--QKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDN

Query:  LVNAPKDQSEVSGNETVALQGNNRHEDSSYIQKI--------CEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRN
          +   D         ++L+ ++R E++SY             ++Q    +EE+ + +++L  L+ ELE L+   + + DD +P   +L+QL +Q+  + 
Subjt:  LVNAPKDQSEVSGNETVALQGNNRHEDSSYIQKI--------CEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRN

Query:  LNLLAMK---DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADI
         N++ +K   D  R  LE K+  L + L    P+A+EK  KLR+ EL+ + + SEI+ RE+E  NL  +L++QPK   R+SYI+ +KEITKNSRK D DI
Subjt:  LNLLAMK---DAERELLENKRRSLQESLCASNPKAQEKLQKLREFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADI

Query:  DRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRE
         RI  ETRELQLE N+IQERLHR+YAVVDE+V R                            E KKD   +Q +KLLTSIH  F +IS KIL TDR +RE
Subjt:  DRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIKVVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRE

Query:  TAEYEKKIAASASRSLNFNKLQADLDAIRRENSYLEQ
        T +YEKK+ +  +R ++  KLQADLDAIR+EN  L++
Subjt:  TAEYEKKIAASASRSLNFNKLQADLDAIRRENSYLEQ

Sequences

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CDS sequence

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ATGGAGGAATCTCAGGAAATCCTTCTGAATTCCCTCCAAAAATCAGGTGTTTCAATCCCTCCAGACGTTTCCTCAATTCGGAACTTAACTCCTCCGCTCTTATTCTCGAT
CTGTGCTCAAGTTTTGAATCGATTACATCCCCAAACCAAAATCCCTTACTCCACTTCTCTCCCGGACTCTGTCGCCGATCAATTCAAGATATGCACTGAAATCGCTTCCG
CTATTAAGGATCTGGGTTTCATTGGAGATACGAGCTTCCACAAGTTCTTGTATCCATCTGAAGAGGACTTGTATAAGTTGATAAGATTCTTGGTGGAGAGGCTTCCTGAA
GCCGCAGATGGAAAATCTAAGGTTTTGGAAGATGGTGATGGTAGAAAAGAAACGAAAGCCGACACTTCCAAATTCTACTATGTGGAGGACCAATCAGAGAAGATCGATAC
CAATGATTCTGTTTTTACCCATCAGAAGGTTGAGAACAAACTTGCTGATCTTAATATTATTGCTGAAGAGACAAAATCTTCAAATTCTATCATTGGTAGATTCTCTGATT
TCTGTCTCGTCCAACAAAGCTTGGGTGAAGCAGCTATGGTCGATAACCTCGTTAATGCTCCCAAGGATCAGTCTGAGGTTTCTGGAAATGAAACAGTTGCACTGCAGGGG
AATAATAGACATGAAGATAGTTCTTACATTCAGAAGATCTGTGAAGATCAAGAGATCAGACCCGTGGAAGAGGTCGCTACAAAGGCTACTGAATTAGAGCATCTTCAAGT
GGAGTTGGAAAGGTTGAAGGCAGTGACCAAAATTGTATTTGATGACAATCGCCCGATTGAATTCCATCTTCAGCAACTGGAGGAGCAAATAAACTCTAGAAACCTGAATC
TTCTTGCAATGAAGGATGCAGAGAGGGAGCTTTTAGAAAATAAAAGGCGAAGTCTACAAGAATCACTATGCGCAAGTAATCCGAAGGCTCAAGAAAAGCTACAAAAATTG
AGGGAGTTTGAATTGGAAAAGAAGCTCATTGAGTCAGAAATCAAGATGCGGGAGGAAGAAAATTCTAATCTTGCAACAGATCTTAAGAAGCAGCCCAAACAATTATCGAG
ACGATCCTATATCAATAGAGTAAAGGAGATCACAAAAAACAGCCGGAAACAAGACGCTGACATCGATCGAATCCTTAAAGAAACTAGAGAGCTTCAGCTAGAATGTAACA
ATATTCAAGAACGCCTCCATAGAACCTACGCAGTTGTGGATGAGCTAGTTCTCAGGTATGCACCACAGAGCAAGTGGGAAATGAAACAGAACTTTGCATCATTTATTAAA
GTTGTCTTAATCAATTGGTTGACAATGATGGAAGCAAAAAAGGATGGTATAGGCAAGCAAGCACACAAGCTTTTGACTAGTATCCATGAGAACTTCGGCGAGATCTCGAA
CAAAATCCTATCTACCGATAGACTAAAAAGAGAAACTGCAGAATACGAAAAGAAGATAGCGGCCTCGGCATCTCGAAGCTTAAATTTTAACAAACTACAAGCTGATCTGG
ATGCTATCAGGAGGGAAAATAGTTACCTAGAGCAACATCTTTGCCAGAAAGTACCCATTGACAAAGTGTAG

mRNA sequence

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AAAAAAAAAAACTATTTCCCCCGTAGTTGATTTCTGAAGACAAAAGAAGTCTGAGAGCGAAAAAGAAGACTGCAAAAATCCAATCCCAGCCATGGAGGAATCTCAGGAAA
TCCTTCTGAATTCCCTCCAAAAATCAGGTGTTTCAATCCCTCCAGACGTTTCCTCAATTCGGAACTTAACTCCTCCGCTCTTATTCTCGATCTGTGCTCAAGTTTTGAAT
CGATTACATCCCCAAACCAAAATCCCTTACTCCACTTCTCTCCCGGACTCTGTCGCCGATCAATTCAAGATATGCACTGAAATCGCTTCCGCTATTAAGGATCTGGGTTT
CATTGGAGATACGAGCTTCCACAAGTTCTTGTATCCATCTGAAGAGGACTTGTATAAGTTGATAAGATTCTTGGTGGAGAGGCTTCCTGAAGCCGCAGATGGAAAATCTA
AGGTTTTGGAAGATGGTGATGGTAGAAAAGAAACGAAAGCCGACACTTCCAAATTCTACTATGTGGAGGACCAATCAGAGAAGATCGATACCAATGATTCTGTTTTTACC
CATCAGAAGGTTGAGAACAAACTTGCTGATCTTAATATTATTGCTGAAGAGACAAAATCTTCAAATTCTATCATTGGTAGATTCTCTGATTTCTGTCTCGTCCAACAAAG
CTTGGGTGAAGCAGCTATGGTCGATAACCTCGTTAATGCTCCCAAGGATCAGTCTGAGGTTTCTGGAAATGAAACAGTTGCACTGCAGGGGAATAATAGACATGAAGATA
GTTCTTACATTCAGAAGATCTGTGAAGATCAAGAGATCAGACCCGTGGAAGAGGTCGCTACAAAGGCTACTGAATTAGAGCATCTTCAAGTGGAGTTGGAAAGGTTGAAG
GCAGTGACCAAAATTGTATTTGATGACAATCGCCCGATTGAATTCCATCTTCAGCAACTGGAGGAGCAAATAAACTCTAGAAACCTGAATCTTCTTGCAATGAAGGATGC
AGAGAGGGAGCTTTTAGAAAATAAAAGGCGAAGTCTACAAGAATCACTATGCGCAAGTAATCCGAAGGCTCAAGAAAAGCTACAAAAATTGAGGGAGTTTGAATTGGAAA
AGAAGCTCATTGAGTCAGAAATCAAGATGCGGGAGGAAGAAAATTCTAATCTTGCAACAGATCTTAAGAAGCAGCCCAAACAATTATCGAGACGATCCTATATCAATAGA
GTAAAGGAGATCACAAAAAACAGCCGGAAACAAGACGCTGACATCGATCGAATCCTTAAAGAAACTAGAGAGCTTCAGCTAGAATGTAACAATATTCAAGAACGCCTCCA
TAGAACCTACGCAGTTGTGGATGAGCTAGTTCTCAGGTATGCACCACAGAGCAAGTGGGAAATGAAACAGAACTTTGCATCATTTATTAAAGTTGTCTTAATCAATTGGT
TGACAATGATGGAAGCAAAAAAGGATGGTATAGGCAAGCAAGCACACAAGCTTTTGACTAGTATCCATGAGAACTTCGGCGAGATCTCGAACAAAATCCTATCTACCGAT
AGACTAAAAAGAGAAACTGCAGAATACGAAAAGAAGATAGCGGCCTCGGCATCTCGAAGCTTAAATTTTAACAAACTACAAGCTGATCTGGATGCTATCAGGAGGGAAAA
TAGTTACCTAGAGCAACATCTTTGCCAGAAAGTACCCATTGACAAAGTGTAGAATGTTTTCTGGATATATATATATATTTCTTTTGAAATAAGCTTTCTACTTTTGGCTT
TTTATTGTGGTTTAAGTTGTGTATAGAAATGGAAGATAGCATCATCATTTTTAATGGTAGGGGATTCCTTGATTTCCAAGTTGCATACTCAACTGGAACTTTGGTGGTTA
AGCAGTTTTTAAGTCTCTTTCATCCCTTGTTGATGCATCTTCTACCAGAAGAATCTTTCCATGTTCAAGTACAAAAACTTATTACTTCATAGTTTGTTTAAAATGAAAAG
AAATTAATACT

Protein sequence

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MEESQEILLNSLQKSGVSIPPDVSSIRNLTPPLLFSICAQVLNRLHPQTKIPYSTSLPDSVADQFKICTEIASAIKDLGFIGDTSFHKFLYPSEEDLYKLIRFLVERLPE
AADGKSKVLEDGDGRKETKADTSKFYYVEDQSEKIDTNDSVFTHQKVENKLADLNIIAEETKSSNSIIGRFSDFCLVQQSLGEAAMVDNLVNAPKDQSEVSGNETVALQG
NNRHEDSSYIQKICEDQEIRPVEEVATKATELEHLQVELERLKAVTKIVFDDNRPIEFHLQQLEEQINSRNLNLLAMKDAERELLENKRRSLQESLCASNPKAQEKLQKL
REFELEKKLIESEIKMREEENSNLATDLKKQPKQLSRRSYINRVKEITKNSRKQDADIDRILKETRELQLECNNIQERLHRTYAVVDELVLRYAPQSKWEMKQNFASFIK
VVLINWLTMMEAKKDGIGKQAHKLLTSIHENFGEISNKILSTDRLKRETAEYEKKIAASASRSLNFNKLQADLDAIRRENSYLEQHLCQKVPIDKV

Lsi05G004990 (gene) of Bottle gourd (USVL1VR-Ls) v1 genome