CuGenDBv2

Gene ID	Lsi07G013770
Organism	Lagenaria siceraria USVL1VR-Ls (Bottle gourd (USVL1VR-Ls) v1)
Description	3-hydroxy-3-methylglutaryl coenzyme A synthase
Genome location	chr07:20021859..20026910
RNA-Seq Expression	Lsi07G013770
Synteny	Lsi07G013770
Gene Ontology terms	GO:0006084 - acetyl-CoA metabolic process (biological process) GO:0010142 - farnesyl diphosphate biosynthetic process, mevalonate pathway (biological process) GO:0016126 - sterol biosynthetic process (biological process) GO:0004421 - hydroxymethylglutaryl-CoA synthase activity (molecular function)
InterPro domains	IPR000590 - Hydroxymethylglutaryl-coenzyme A synthase, active site IPR010122 - Hydroxymethylglutaryl-CoA synthase, eukaryotic IPR013528 - Hydroxymethylglutaryl-coenzyme A synthase, N-terminal IPR013746 - Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain IPR016039 - Thiolase-like

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6577575.1 Hydroxymethylglutaryl-CoA synthase, partial [Cucurbita argyrosperma subsp. sororia]

3.7e-257

95.27

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Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MA NVGILA+DIYFPPTY++QEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAML+GPDAPI FESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSIS+ADYFVFHSPYNKLVQKSFARLLFNDF RNASSIDEVAKEKLAPFSTLSNDE+YQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK +SL GNRV+LFSYGSGSTATMFSLKLNEGQ PFSLSNISAILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVEIMQ+MEHRYGAKDFVTSKDCSLL  G+YYLTEVDSLYRRFYAKKDGESEK+ENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

XP_004147967.1 hydroxymethylglutaryl-CoA synthase [Cucumis sativus]

6.7e-259

96.35

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Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MANNVGILA+DIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVV SLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLE-GKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLE
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLE GKQFS+SNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDE AKEKLAPFSTLSNDESYQSRDLE
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLE-GKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLE

Query:  KITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELV
        KITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK  SL+GNRV+LFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELV
Subjt:  KITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELV

Query:  PEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        PEKFVEIMQ+MEHRYGAKDFVTSKDCSLL+ GTYYLTEVDSLYRRFYAKK+G SEKIENGVVANGH
Subjt:  PEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

XP_008448952.1 PREDICTED: hydroxymethylglutaryl-CoA synthase [Cucumis melo]

2.3e-259

96.34

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Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MANNVGILA+DIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVV SLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSID  AKEKLAPFS LSNDESYQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK +SL+GNRV+LFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVEIMQ+MEHRYGAKDFVTSKDCSLL+ GTYYLTEVDSLYRRFYAKK+G SEKIENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

XP_023553213.1 hydroxymethylglutaryl-CoA synthase-like [Cucurbita pepo subsp. pepo]

1.3e-257

95.48

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Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MA NVGILA+DIYFPPTY+QQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAML+GPDAPI FESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSIS+ADYFVFHSPYNKLVQKSFARLLFNDF RNASSIDEVAKEKLAPFSTLSNDE+YQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK +SL GNRV+LFSYGSGSTATMFSLKLNEGQ PFSLSNISAILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVEIMQ+MEHRYGAKDFVTSKDCSLL  G+YYLTEVDSLYRRFYAKKDGESEK+ENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

XP_038903028.1 hydroxymethylglutaryl-CoA synthase [Benincasa hispida]

3.8e-262

97.42

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Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MANNVGILA+DIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLT VTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDE AKEKLAPFS LSNDESYQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK +SL+GNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVEIMQ+MEHRYGAKDFVTSKDCSLL+PGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L5T1 3-hydroxy-3-methylglutaryl coenzyme A synthase

3.3e-259

96.35

Show/hide

Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MANNVGILA+DIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVV SLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLE-GKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLE
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLE GKQFS+SNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDE AKEKLAPFSTLSNDESYQSRDLE
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLE-GKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLE

Query:  KITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELV
        KITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK  SL+GNRV+LFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELV
Subjt:  KITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELV

Query:  PEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        PEKFVEIMQ+MEHRYGAKDFVTSKDCSLL+ GTYYLTEVDSLYRRFYAKK+G SEKIENGVVANGH
Subjt:  PEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

A0A1S3BKB7 3-hydroxy-3-methylglutaryl coenzyme A synthase

1.1e-259

96.34

Show/hide

Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MANNVGILA+DIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVV SLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSID  AKEKLAPFS LSNDESYQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK +SL+GNRV+LFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVEIMQ+MEHRYGAKDFVTSKDCSLL+ GTYYLTEVDSLYRRFYAKK+G SEKIENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

A0A5D3D7H1 3-hydroxy-3-methylglutaryl coenzyme A synthase

1.1e-259

96.34

Show/hide

Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MANNVGILA+DIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVV SLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSID  AKEKLAPFS LSNDESYQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK +SL+GNRV+LFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVEIMQ+MEHRYGAKDFVTSKDCSLL+ GTYYLTEVDSLYRRFYAKK+G SEKIENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

A0A6J1E6B9 3-hydroxy-3-methylglutaryl coenzyme A synthase

6.8e-257

95.05

Show/hide

Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MA NVGILA+DI+FPPTY++QEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAAL NCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAML+GPDAPI FESKLRGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSIS+ADYFVFHSPYNKLVQKSFARLLFNDF RNASSIDEVAKEKLAPFSTLSNDE+YQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ITQQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK +SL GNRV+LFSYGSGSTATMFSLKLNEGQ PFSLSNISAILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVEIMQ+MEHRYGAKDFVTSKDCSLL  G+YYLTEVDSLYRRFYAKKDGESEK+ENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

K7NBW5 3-hydroxy-3-methylglutaryl coenzyme A synthase

6.8e-257

95.05

Show/hide

Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MA NVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFES++RGSHMSHVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYKQLCHKYEKLEGKQFSIS+ADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLS DESYQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        I+QQLAKPLYD KVQPSTLIPKQVGNMYTASLYAAFISLLHNK ++L GNRVILFSYGSGSTATMFSLKLNEGQ+PFSLSNI+AILNVDKKLKSRHELVP
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKF+EIM++MEHRYGAKDFVTSKDCSLL+PGTYYLTEVDSLYRRFYAK DG+S + ENGVVANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

SwissProt top hits

e value

%identity

Alignment

P54872 Hydroxymethylglutaryl-CoA synthase A

2.4e-126

50.34

Show/hide

Query:  NVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKH
        N+GI  +++YFP TYV QE LE  DG S+GKYT+GLGQ  MAFC + ED+ S+SL  V +L++K+ +DP  IGRLEVG+ETVIDKSKS+KT LM +F KH
Subjt:  NVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKH

Query:  GNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPV
        GNT I+G+D+ NACYGGT+AL N + W+ESS WDGR  +VV  D AVY +GPARPTGGA  +AMLIGP+API FES LRG HM +VYDFYKP++ SEYP 
Subjt:  GNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPV

Query:  VDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEKITQ
        VDGKLS +CY  A+D+CY +    +EK  GK FS+   D+ +FHSPYNKLVQKSF R+L+NDF  N    ++     L  +  +  +++Y    LEK   
Subjt:  VDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEKITQ

Query:  QLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVPEKF
         + K  Y  KV P+TL+ KQ+GN Y  S Y+  +SLL  K + L+G RV+ FSYGSG  A+ FS K+ +      +++I   +++  +L  R  + PE F
Subjt:  QLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVPEKF

Query:  VEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFY
         E + + E R+  K++V S + + + PG++YL+ VD+   R Y
Subjt:  VEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFY

P54873 Hydroxymethylglutaryl-CoA synthase

1.4e-222

80.73

Show/hide

Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MA NVGILA+DIYFPPT VQQEALEAHDGASKGKYTIGLGQDC+AFCTE+EDVISMS   VTSL EKY IDP QIGRLEVGSETVIDKSKSIKTFLMQ+F
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EK GNTD+EGVDSTNACYGGTAALLNCVNWVES+SWDGRYGLV+CTDSAVYAEGPARPTGGAAAIAMLIGPDAPI FESKLR SHM+HVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYK LC+K+EK+EGK+FSI++ADY VFHSPYNKLVQKSFARLL+NDF RNASSIDE AKEK  P+S+L+ DESYQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ++QQ+AKP YD KVQP+TLIPK+VGNMYTASLYAAF SL+H K + L G RV++FSYGSGSTATMFSL+LN+ + PFS+SNI+++++V  KLK+RHE  P
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKD--CSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVE M++MEHRYGAKDFVT+K+    LLAPGTYYL EVDSLYRRFY KK       E+G VANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKD--CSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

P54961 Hydroxymethylglutaryl-CoA synthase 1

7.8e-125

50.22

Show/hide

Query:  NNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEK
        ++VGI+A+++ FP  YV Q  LE +D  S GKYT+GLGQ  M FCT+ ED+ S+ LTVV+ L+E++ I   QIGRLEVG+ET++DKSKS+KT LMQ+F+ 
Subjt:  NNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEK

Query:  HGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYP
          NTDIEGVD+ NACYGGT+AL N ++WVESSSWDGRY LVV  D AVYA+G ARPTGGA A+AML+G +AP+ F+  +R SHM H YDFYKP+L+S YP
Subjt:  HGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYP

Query:  VVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEKIT
         VDGKLS  CYL ALD CY+  C K +K  G++F I   D  +FH+PY KLVQKS ARL+ NDF R +          L     +  +++Y  R++EK  
Subjt:  VVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEKIT

Query:  QQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNK-RDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSN--ISAILNVDKKLKSRHELV
           +K +++ K +PS L+  QVGNMYT SLY   +SLL +K    L G RV LFSYGSG  ++MFSL+++   +  S     +S + ++  +L  RH++ 
Subjt:  QQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNK-RDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSN--ISAILNVDKKLKSRHELV

Query:  PEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDG
        PE+F + M+  EH +    +       +L PGT+YL  VDSLYRR Y +  G
Subjt:  PEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKKDG

Q01581 Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1.1e-121

Show/hide

Query:  NVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKH
        +VGI+A++IYFP  YV Q  LE +DG   GKYTIGLGQ  M FCT+ ED+ S+ +TVV +L+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ 
Subjt:  NVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKH

Query:  GNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPV
        GNTDIEG+D+TNACYGGTAA+ N VNW+ESSSWDGRY LVV  D AVYA G ARPTGG  A+A+LIGP+AP+ FE  LRG+HM H YDFYKP++ SEYP+
Subjt:  GNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPV

Query:  VDGKLSQTCYLIALDSCYKQLC---HKYEKLEG--KQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDL
        VDGKLS  CYL ALD CY   C   H   + EG  K F++++  + +FHSPY KLVQKS AR+L NDF  + +         L  F  +  +++Y  RD+
Subjt:  VDGKLSQTCYLIALDSCYKQLC---HKYEKLEG--KQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDL

Query:  EKITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLL-HNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFS-LSNISAIL-NVDKKLKSR
        EK   + +  L+  K + S L+  Q GNMYT+S+Y +  S+L       L G R+ +FSYGSG  AT++SLK+ +   P S L  I+A L ++  +L SR
Subjt:  EKITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLL-HNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFS-LSNISAIL-NVDKKLKSR

Query:  HELVPEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKK
          + P+ F E M++ E  +   +++       L  GT+YL  VD  +RR YA++
Subjt:  HELVPEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKK

Q5R7Z9 Hydroxymethylglutaryl-CoA synthase, cytoplasmic

8.1e-122

Show/hide

Query:  NVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKH
        +VGI+A++IYFP  YV Q  LE +DG + GKYTIGLGQ  M FCT+ ED+ S+ +TVV +L+E+  +    IGRLEVG+ET+IDKSKS+KT LMQ+FE+ 
Subjt:  NVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKH

Query:  GNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPV
        GNTDIEG+D+TNACYGGTAA+ N VNW+ESSSWDGRY LVV  D AVYA G ARPTGG  A+A+LIGP+AP+ FE  LRG+HM H YDFYKP++ SEYP+
Subjt:  GNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPV

Query:  VDGKLSQTCYLIALDSCYKQLCHKYE---KLEG--KQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDL
        VDGKLS  CYL ALD CY   C K     + EG  K F++++  + +FHSPY KLVQKS AR+L NDF  + +         L  F  +  +++Y  RD+
Subjt:  VDGKLSQTCYLIALDSCYKQLCHKYE---KLEG--KQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDL

Query:  EKITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLL-HNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFS-LSNISAIL-NVDKKLKSR
        EK   + +  L+  K + S L+  Q GNMYT+S+Y +  S+L       L G R+ +FSYGSG  AT++SLK+ +   P S L  I+A L ++  +L SR
Subjt:  EKITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLL-HNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFS-LSNISAIL-NVDKKLKSR

Query:  HELVPEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKK
          + P+ F E M++ E  +   +++       L  GT+YL  VD  +RR YA++
Subjt:  HELVPEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDSLYRRFYAKK

Arabidopsis top hits

e value

%identity

Alignment

AT4G11820.1 hydroxymethylglutaryl-CoA synthase / HMG-CoA synthase / 3-hydroxy-3-methylglutaryl coenzyme A synthase

1.5e-192

79.37

Show/hide

Query:  MSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGP
        MS   VTSL EKY IDP QIGRLEVGSETVIDKSKSIKTFLMQ+FEK GNTD+EGVDSTNACYGGTAALLNCVNWVES+SWDGRYGLV+CTDSAVYAEGP
Subjt:  MSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGP

Query:  ARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQ
        ARPTGGAAAIAMLIGPDAPI FESKLR SHM+HVYDFYKPNLASEYPVVDGKLSQTCYL+ALDSCYK LC+K+EK+EGK+FSI++ADY VFHSPYNKLVQ
Subjt:  ARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQ

Query:  KSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEKITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILF
        KSFARLL+NDF RNASSIDE AKEK  P+S+L+ DESYQSRDLEK++QQ+AKP YD KVQP+TLIPK+VGNMYTASLYAAF SL+H K + L G RV++F
Subjt:  KSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEKITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILF

Query:  SYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVPEKFVEIMQVMEHRYGAKDFVTSKD--CSLLAPGTYYLTEVDSLYRRFYAKKDGES
        SYGSGSTATMFSL+LN+ + PFS+SNI+++++V  KLK+RHE  PEKFVE M++MEHRYGAKDFVT+K+    LLAPGTYYL EVDSLYRRFY KK    
Subjt:  SYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVPEKFVEIMQVMEHRYGAKDFVTSKD--CSLLAPGTYYLTEVDSLYRRFYAKKDGES

Query:  EKIENGVVANGH
           E+G VANGH
Subjt:  EKIENGVVANGH

AT4G11820.2 hydroxymethylglutaryl-CoA synthase / HMG-CoA synthase / 3-hydroxy-3-methylglutaryl coenzyme A synthase

9.8e-224

80.73

Show/hide

Query:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF
        MA NVGILA+DIYFPPT VQQEALEAHDGASKGKYTIGLGQDC+AFCTE+EDVISMS   VTSL EKY IDP QIGRLEVGSETVIDKSKSIKTFLMQ+F
Subjt:  MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIF

Query:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE
        EK GNTD+EGVDSTNACYGGTAALLNCVNWVES+SWDGRYGLV+CTDSAVYAEGPARPTGGAAAIAMLIGPDAPI FESKLR SHM+HVYDFYKPNLASE
Subjt:  EKHGNTDIEGVDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASE

Query:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK
        YPVVDGKLSQTCYL+ALDSCYK LC+K+EK+EGK+FSI++ADY VFHSPYNKLVQKSFARLL+NDF RNASSIDE AKEK  P+S+L+ DESYQSRDLEK
Subjt:  YPVVDGKLSQTCYLIALDSCYKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEK

Query:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP
        ++QQ+AKP YD KVQP+TLIPK+VGNMYTASLYAAF SL+H K + L G RV++FSYGSGSTATMFSL+LN+ + PFS+SNI+++++V  KLK+RHE  P
Subjt:  ITQQLAKPLYDVKVQPSTLIPKQVGNMYTASLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVP

Query:  EKFVEIMQVMEHRYGAKDFVTSKD--CSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH
        EKFVE M++MEHRYGAKDFVT+K+    LLAPGTYYL EVDSLYRRFY KK       E+G VANGH
Subjt:  EKFVEIMQVMEHRYGAKDFVTSKD--CSLLAPGTYYLTEVDSLYRRFYAKKDGESEKIENGVVANGH

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGCCAACAATGTTGGAATTCTCGCTGTAGATATCTACTTCCCTCCTACCTACGTTCAGCAGGAAGCATTGGAAGCTCATGATGGTGCAAGCAAGGGGAAATACACTAT
TGGGCTTGGACAGGATTGCATGGCATTCTGTACTGAGGTTGAAGATGTCATCTCGATGAGCTTGACAGTTGTCACTTCCCTTCTTGAAAAGTATGGAATTGATCCAAAAC
AAATTGGCCGGCTAGAAGTAGGCAGTGAGACTGTTATAGATAAAAGCAAATCAATTAAGACTTTCCTGATGCAAATATTTGAGAAACATGGAAATACCGATATTGAAGGT
GTTGATTCAACTAACGCGTGCTATGGGGGTACAGCTGCTCTATTAAACTGTGTCAACTGGGTAGAGAGCAGCTCCTGGGATGGGCGTTATGGTCTTGTGGTGTGCACAGA
TAGTGCGGTCTACGCTGAAGGACCAGCTCGTCCTACTGGTGGGGCTGCAGCTATTGCCATGCTGATAGGACCTGATGCTCCTATTGCTTTTGAAAGCAAGTTGAGGGGAA
GCCATATGTCTCACGTTTATGATTTTTACAAGCCTAACCTAGCCAGTGAATACCCGGTTGTTGATGGTAAGCTCTCTCAAACATGTTACCTCATTGCCTTGGATTCATGC
TACAAACAATTATGTCACAAGTATGAGAAACTGGAGGGCAAACAATTTTCCATTTCTAACGCTGACTATTTTGTATTTCATTCTCCCTATAACAAGCTCGTGCAGAAGAG
CTTTGCTCGATTGCTCTTTAATGACTTCAAGAGAAATGCCAGCTCAATAGATGAAGTTGCTAAAGAAAAGCTGGCCCCATTTTCAACCTTGTCTAACGATGAAAGTTACC
AGAGTCGGGATCTCGAAAAGATAACCCAACAACTTGCAAAGCCTCTTTATGATGTAAAGGTCCAACCCTCCACTTTGATACCAAAGCAAGTTGGAAACATGTATACTGCT
TCTCTCTATGCAGCATTTATATCACTTCTTCACAACAAGCGTGATTCACTGATAGGAAATAGGGTGATATTGTTCTCTTATGGAAGTGGGTCAACTGCAACGATGTTCTC
ATTGAAACTCAATGAAGGTCAAAATCCCTTTAGTTTGTCCAACATTTCAGCTATCTTGAACGTGGACAAAAAGTTGAAATCGAGGCATGAGTTGGTACCCGAGAAATTTG
TCGAAATAATGCAGGTGATGGAGCATCGGTACGGCGCCAAGGACTTCGTGACGAGCAAGGACTGCAGCCTGCTAGCACCAGGCACGTACTATCTCACTGAAGTTGATTCA
TTATACAGGAGATTCTACGCCAAGAAGGATGGCGAAAGTGAAAAGATTGAGAATGGTGTGGTTGCTAATGGCCACTGA

mRNA sequence

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CGCCCCCATGTGAGCCTCACCATCTTTCTCTGCTACTTTCAAGGATTTCCTCTCTCTTCTCTCTCAATTTTCTTCTCTCCATTTCTTCGTTTCCACACCAAAACGAGGCT
CCAGAAATGGCCAACAATGTTGGAATTCTCGCTGTAGATATCTACTTCCCTCCTACCTACGTTCAGCAGGAAGCATTGGAAGCTCATGATGGTGCAAGCAAGGGGAAATA
CACTATTGGGCTTGGACAGGATTGCATGGCATTCTGTACTGAGGTTGAAGATGTCATCTCGATGAGCTTGACAGTTGTCACTTCCCTTCTTGAAAAGTATGGAATTGATC
CAAAACAAATTGGCCGGCTAGAAGTAGGCAGTGAGACTGTTATAGATAAAAGCAAATCAATTAAGACTTTCCTGATGCAAATATTTGAGAAACATGGAAATACCGATATT
GAAGGTGTTGATTCAACTAACGCGTGCTATGGGGGTACAGCTGCTCTATTAAACTGTGTCAACTGGGTAGAGAGCAGCTCCTGGGATGGGCGTTATGGTCTTGTGGTGTG
CACAGATAGTGCGGTCTACGCTGAAGGACCAGCTCGTCCTACTGGTGGGGCTGCAGCTATTGCCATGCTGATAGGACCTGATGCTCCTATTGCTTTTGAAAGCAAGTTGA
GGGGAAGCCATATGTCTCACGTTTATGATTTTTACAAGCCTAACCTAGCCAGTGAATACCCGGTTGTTGATGGTAAGCTCTCTCAAACATGTTACCTCATTGCCTTGGAT
TCATGCTACAAACAATTATGTCACAAGTATGAGAAACTGGAGGGCAAACAATTTTCCATTTCTAACGCTGACTATTTTGTATTTCATTCTCCCTATAACAAGCTCGTGCA
GAAGAGCTTTGCTCGATTGCTCTTTAATGACTTCAAGAGAAATGCCAGCTCAATAGATGAAGTTGCTAAAGAAAAGCTGGCCCCATTTTCAACCTTGTCTAACGATGAAA
GTTACCAGAGTCGGGATCTCGAAAAGATAACCCAACAACTTGCAAAGCCTCTTTATGATGTAAAGGTCCAACCCTCCACTTTGATACCAAAGCAAGTTGGAAACATGTAT
ACTGCTTCTCTCTATGCAGCATTTATATCACTTCTTCACAACAAGCGTGATTCACTGATAGGAAATAGGGTGATATTGTTCTCTTATGGAAGTGGGTCAACTGCAACGAT
GTTCTCATTGAAACTCAATGAAGGTCAAAATCCCTTTAGTTTGTCCAACATTTCAGCTATCTTGAACGTGGACAAAAAGTTGAAATCGAGGCATGAGTTGGTACCCGAGA
AATTTGTCGAAATAATGCAGGTGATGGAGCATCGGTACGGCGCCAAGGACTTCGTGACGAGCAAGGACTGCAGCCTGCTAGCACCAGGCACGTACTATCTCACTGAAGTT
GATTCATTATACAGGAGATTCTACGCCAAGAAGGATGGCGAAAGTGAAAAGATTGAGAATGGTGTGGTTGCTAATGGCCACTGAAATAAAAAATGACAATAAACAAGTGG
ACTGAAGCCAAATGCTCTGCTCTTCATTTAATTATTGTTAGTGTCAACAAGAAATTTTAAGCTATAGAAGGCAGTACGTTCACAACTGGTAGTTTTCTGTTGTTCTTTTC
CCCTTCCGTTAGGAAAATTGTCTCAATAATCAGTTGGCTTTATTTATTCACAAGATACAATGTAATGCTGTTGATGATGATGATAATGTAGACTCCTTCCCTTCCCCCCA
TTTTTCACTTCCATTGGTAATTATCATCAAATTTGTTTGTTCATCTGTCTTCAAATTCCCAAAGTAATGGAGAACTGTATCTCGAGGCTTTCGGTAGGAACGAGTGTAAT
GTAAGCAAAATCATGGTGTAAATCTGTCCTCATTCTACCTTCATCTGGTCACTTGCTACTTTCCTTCAGTTTCTTTTTCGAGAAACTTTTGGCTTTCTAGTTTTTAGTTA
GTTTAAATTATAAAAAATACGTTCGAACTCGAACATTATGTTTGTTTCAAAAATATACTCATCGTT

Protein sequence

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MANNVGILAVDIYFPPTYVQQEALEAHDGASKGKYTIGLGQDCMAFCTEVEDVISMSLTVVTSLLEKYGIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKHGNTDIEG
VDSTNACYGGTAALLNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAIAMLIGPDAPIAFESKLRGSHMSHVYDFYKPNLASEYPVVDGKLSQTCYLIALDSC
YKQLCHKYEKLEGKQFSISNADYFVFHSPYNKLVQKSFARLLFNDFKRNASSIDEVAKEKLAPFSTLSNDESYQSRDLEKITQQLAKPLYDVKVQPSTLIPKQVGNMYTA
SLYAAFISLLHNKRDSLIGNRVILFSYGSGSTATMFSLKLNEGQNPFSLSNISAILNVDKKLKSRHELVPEKFVEIMQVMEHRYGAKDFVTSKDCSLLAPGTYYLTEVDS
LYRRFYAKKDGESEKIENGVVANGH

Lsi07G013770 (gene) of Bottle gourd (USVL1VR-Ls) v1 genome