CuGenDBv2

Gene ID	Lsi09G007270
Organism	Lagenaria siceraria USVL1VR-Ls (Bottle gourd (USVL1VR-Ls) v1)
Description	sodium/hydrogen exchanger 8
Genome location	chr09:8364274..8366469
RNA-Seq Expression	Lsi09G007270
Synteny	Lsi09G007270
Gene Ontology terms	GO:0051453 - regulation of intracellular pH (biological process) GO:0071805 - potassium ion transmembrane transport (biological process) GO:0098656 - anion transmembrane transport (biological process) GO:0098719 - sodium ion import across plasma membrane (biological process) GO:1902600 - proton transmembrane transport (biological process) GO:0005886 - plasma membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0015385 - sodium:proton antiporter activity (molecular function) GO:0015386 - potassium:proton antiporter activity (molecular function)
InterPro domains	IPR018422 - Cation/H+ exchanger, CPA1 family

Homology

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GenBank top hits

e value

%identity

Alignment

KGN49745.1 hypothetical protein Csa_017807 [Cucumis sativus]

2.7e-32

96.1

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NGASWG+LI+LYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

NP_001292661.1 son of sevenless homolog 1 [Cucumis sativus]

2.7e-32

96.1

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NGASWG+LI+LYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

XP_008466844.1 PREDICTED: sodium/hydrogen exchanger 8 [Cucumis melo]

1.3e-31

94.81

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NGASWG+LILLYV+VQASRF+VVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

XP_031740809.1 son of sevenless homolog 1 isoform X1 [Cucumis sativus]

2.7e-32

96.1

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NGASWG+LI+LYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

XP_038875389.1 sodium/hydrogen exchanger 8 isoform X1 [Benincasa hispida]

3.0e-31

94.81

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NG SWGFLILLY YVQASRFMVV VLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KJ31 Cyclic nucleotide-binding domain-containing protein

1.3e-32

96.1

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NGASWG+LI+LYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

A0A1S3CS69 sodium/hydrogen exchanger 8

6.4e-32

94.81

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NGASWG+LILLYV+VQASRF+VVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

A0A6J1GVG1 sodium/hydrogen exchanger 7 isoform X3

5.4e-31

93.51

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGILN+GASWGFLILLY YVQASR MVVGVLYPFLRYFGYGLDWKEATIL WSGLRGAVAL+LSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

A0A6J1GXP6 sodium/hydrogen exchanger 8 isoform X1

5.4e-31

93.51

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGILN+GASWGFLILLY YVQASR MVVGVLYPFLRYFGYGLDWKEATIL WSGLRGAVAL+LSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

H9DVC6 Plasmalemma Na+/H+ antiporter

1.3e-32

96.1

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEGVLGSEGIL+NGASWG+LI+LYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

SwissProt top hits

e value

%identity

Alignment

Q3YL57 Sodium/hydrogen exchanger 8

1.1e-20

67.53

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GV+IAE VL  + I   G SW FL LLY+YVQ SR +VVGVLYP L   GYGLDWKE+ IL WSGLRGAV+LSL+LS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

Q9LKW9 Sodium/hydrogen exchanger 7

1.1e-23

72.73

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEG+L S+ I   G SW FL LLYVY+Q SR +VVGVLYP L  FGYGLDWKE+ IL+WSGLRGAVAL+LSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

Arabidopsis top hits

e value

%identity

Alignment

AT1G14660.1 Na+/H+ exchanger 8

7.8e-22

67.53

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GV+IAE VL  + I   G SW FL LLY+YVQ SR +VVGVLYP L   GYGLDWKE+ IL WSGLRGAV+LSL+LS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

AT1G14660.2 Na+/H+ exchanger 8

1.9e-04

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASR
        GV+IAE VL  + I   G SW FL LLY+YVQ SR
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASR

AT2G01980.1 sodium proton exchanger, putative (NHX7) (SOS1)

7.5e-25

72.73

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Query:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS
        GVVIAEG+L S+ I   G SW FL LLYVY+Q SR +VVGVLYP L  FGYGLDWKE+ IL+WSGLRGAVAL+LSLS
Subjt:  GVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLS

Sequences

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CDS sequence

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ATGTTACTTCTTGCCTTCAAAGCAGTCGTAGAGTGCAAGAATTTCCATAATATTGGAGTTGTTATCGCTGAAGGAGTTCTTGGAAGCGAAGGAATTCTTAATAATGGAGC
TTCATGGGGCTTCCTCATTCTGCTTTATGTGTATGTGCAAGCTTCTCGATTTATGGTTGTTGGAGTATTGTATCCATTTCTGCGGTATTTTGGATATGGATTGGATTGGA
AAGAAGCTACAATACTGATATGGTCAGGTCTGCGTGGAGCTGTTGCTTTGTCACTTTCACTGTCATATATTTTCCCAATCGCTAGAAACCAAAGGAAAGGTGTGAAAGTA
ACCAATGGACCAAATGAATCTCTTCAGACTATTTCCATCCATGTTTTTTCCTTCTTGGTGGTTGCTTTTTTGGCTTTCTTTCTCTCCCTTTTGGGTTTGGAAAGTTGTTT
CCCAGTAATTTTCCTAACCTCATGTGTTGAGGATAAAATAAGGATCAAGTTCACTCCAACTTAA

mRNA sequence

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Protein sequence

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MLLLAFKAVVECKNFHNIGVVIAEGVLGSEGILNNGASWGFLILLYVYVQASRFMVVGVLYPFLRYFGYGLDWKEATILIWSGLRGAVALSLSLSYIFPIARNQRKGVKV
TNGPNESLQTISIHVFSFLVVAFLAFFLSLLGLESCFPVIFLTSCVEDKIRIKFTPT

Lsi09G007270 (gene) of Bottle gourd (USVL1VR-Ls) v1 genome