CuGenDBv2

Gene ID	MC01g1505
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	cyclic phosphodiesterase
Genome location	MC01:19384968..19386935
RNA-Seq Expression	MC01g1505
Synteny	MC01g1505
Gene Ontology terms	GO:0009187 - cyclic nucleotide metabolic process (biological process) GO:0004113 - 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity (molecular function) GO:0016874 - ligase activity (molecular function)
InterPro domains	IPR009097 - Cyclic phosphodiesterase IPR012386 - 2',3'-cyclic-nucleotide 3'-phosphodiesterase

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008439703.1 PREDICTED: cyclic phosphodiesterase-like [Cucumis melo]

6.71e-97

72.4

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Query:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL
        M NP     + SEE+ NVYSVWALPPEDV+ RIE LM+ LRSEF GPQFEPHITVVGAI LT +DAL KF TAC+G KAYQATVDHV+TGTFFYQCVFLL
Subjt:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL

Query:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS
        I PT EVV+ SSH C+ FG+KNSTPYMPH+SLLYAH++DE+K + K+IADKLDE + GL FP+TRLAL+KTDT DETL+SWEKI E++L  S
Subjt:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS

XP_022142373.1 cyclic phosphodiesterase [Momordica charantia]

2.26e-135

100

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Query:  MANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPT
        MANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPT
Subjt:  MANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPT

Query:  PEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS
        PEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS
Subjt:  PEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS

XP_022978766.1 cyclic phosphodiesterase-like [Cucurbita maxima]

2.34e-97

75.66

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Query:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL
        MANP     + SE +KNVYSVWALPPEDV  RI TLM+ LRSEF GPQFEPHITVVGAI LT DDAL KFR+ACEG KAYQATVD V+TGTFFYQCVFLL
Subjt:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL

Query:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        I PT +VV+ SSHCC  FGYKNSTPYMPHLSLLYA+++DE+K + K++A+KLDE I GLSFPVTRLALYKTDT DETL+SWEKI E +L
Subjt:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

XP_023522563.1 cyclic phosphodiesterase-like [Cucurbita pepo subsp. pepo]

1.65e-97

76.09

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Query:  ANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTP
        + P + SE +KNVYSVWALPPEDV  RI TLM+ LRSEF GPQFEPHITVVGAI LT DDAL KFR+ACEG KAYQATVD V+TGTFFYQCVFLLI PT 
Subjt:  ANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTP

Query:  EVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        EVV+ SSHCC  FGYKNSTPYMPHLSLLYA+++DE+K + K++A+KLDE I GLSFP+TRLALYKTDT DETL+SWEKI E +L
Subjt:  EVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

XP_023543945.1 cyclic phosphodiesterase-like isoform X2 [Cucurbita pepo subsp. pepo]

2.34e-97

75.54

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Query:  ANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTP
        + P + SE +KNVYSVWALPPEDV  RI TLM+ LRSEF GPQFEPHITVVGAI LT DDAL KFR+ACEG KAYQATVD V+TGTFFYQCVFLLI PT 
Subjt:  ANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTP

Query:  EVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        +VV+ SSHCC  FGYKNSTPYMPHLSLLYA+++DE+K + K++A+KLDE I GLSFP+TRLALYKTDT DETL+SWEKI E +L
Subjt:  EVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KLS9 Uncharacterized protein

9.86e-92

69.27

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Query:  MANPTEQS----EEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL
        M NP   S    EE+ +VYSVWALPPEDV+ RIE LM  LRSEF GP FEPHITVVGAI LT +DAL KFRTAC+G KAYQATVDHV TGTFFYQCVFLL
Subjt:  MANPTEQS----EEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL

Query:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS
        I PT EVV+ SSH C+ F +K+STPYMPH+SLLY+H++DE++ + K+IADKLDE + GL FP+TRLAL KTDT DETL+SW+KI E++L  S
Subjt:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS

A0A1S3AYZ1 cyclic phosphodiesterase-like

3.25e-97

72.4

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Query:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL
        M NP     + SEE+ NVYSVWALPPEDV+ RIE LM+ LRSEF GPQFEPHITVVGAI LT +DAL KF TAC+G KAYQATVDHV+TGTFFYQCVFLL
Subjt:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL

Query:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS
        I PT EVV+ SSH C+ FG+KNSTPYMPH+SLLYAH++DE+K + K+IADKLDE + GL FP+TRLAL+KTDT DETL+SWEKI E++L  S
Subjt:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS

A0A6J1CN42 cyclic phosphodiesterase

1.10e-135

100

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Query:  MANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPT
        MANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPT
Subjt:  MANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPT

Query:  PEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS
        PEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS
Subjt:  PEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS

A0A6J1EGC1 cyclic phosphodiesterase-like

4.25e-95

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Query:  ANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTP
        + P + SE +KNVYSVWALPPEDV  RI TLM+ LRSEF GPQFEPHITVVGAI LT DDAL KFR+ACEG KAYQATVD V+TGTFFYQCVFLLI PT 
Subjt:  ANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTP

Query:  EVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        +VV+ SSHCC  FGYKN TPYMPHLSLLYA+++DE+K + K++A+KLDE I GLSFP+TRLALYKTDT DETL+SWEKI E +L
Subjt:  EVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

A0A6J1INY2 cyclic phosphodiesterase-like

1.13e-97

75.66

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Query:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL
        MANP     + SE +KNVYSVWALPPEDV  RI TLM+ LRSEF GPQFEPHITVVGAI LT DDAL KFR+ACEG KAYQATVD V+TGTFFYQCVFLL
Subjt:  MANPT----EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLL

Query:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        I PT +VV+ SSHCC  FGYKNSTPYMPHLSLLYA+++DE+K + K++A+KLDE I GLSFPVTRLALYKTDT DETL+SWEKI E +L
Subjt:  IRPTPEVVDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

SwissProt top hits

e value

%identity

Alignment

O04147 Cyclic phosphodiesterase

2.5e-53

57.06

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Query:  EEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEVVDISS
        E +K+VYSVWALP E+   R + LM  LRSEF GP+F PH+TV  +  LT D+A   F +AC+G KAY ATVD V+TGTFF+QCVFLL++ TPEV++   
Subjt:  EEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEVVDISS

Query:  HCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        HC   F    +TPYMPHLSLLYA LT+EEK   ++ A  LD  + GLSF + RLAL KTDTED+TLE+WE +   NL
Subjt:  HCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

Q6CGD3 2',3'-cyclic-nucleotide 3'-phosphodiesterase

2.9e-06

22.64

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Query:  SVWALPPEDVAV--RIETLMSGLRSEFRGPQ-FEPHITVV--------GAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEVV
        S+W  PP +  +  ++ T + GL+  F   + FEPHIT+         G +    D A+   +   +G   +Q  +  V  G+ F++ V+L + PTPE++
Subjt:  SVWALPPEDVAV--RIETLMSGLRSEFRGPQ-FEPHITVV--------GAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEVV

Query:  DISSHCCRIFGYK--------------------------------NSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGI------TGLSFPVTRLALYK
         ++  C   F Y                                     Y PH+SL+Y+ L   E    + I  +L++        +GL +   R AL +
Subjt:  DISSHCCRIFGYK--------------------------------NSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGI------TGLSFPVTRLALYK

Query:  TDTEDETLESWE
            +  ++ WE
Subjt:  TDTEDETLESWE

Arabidopsis top hits

e value

%identity

Alignment

AT4G18930.1 RNA ligase/cyclic nucleotide phosphodiesterase family protein

1.7e-54

57.06

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Query:  EEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEVVDISS
        E +K+VYSVWALP E+   R + LM  LRSEF GP+F PH+TV  +  LT D+A   F +AC+G KAY ATVD V+TGTFF+QCVFLL++ TPEV++   
Subjt:  EEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEVVDISS

Query:  HCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        HC   F    +TPYMPHLSLLYA LT+EEK   ++ A  LD  + GLSF + RLAL KTDTED+TLE+WE +   NL
Subjt:  HCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

AT4G18940.1 RNA ligase/cyclic nucleotide phosphodiesterase family protein

6.5e-41

43.96

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Query:  EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIP--LTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEV
        E  EE+K +Y++WA+P +DV  R++ LM GLRSEF GP F+PH+T+VG  P  LT  +A   F++ACEG K Y ATVD V+ GT ++QC+++ +R T EV
Subjt:  EQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIP--LTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEV

Query:  VDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL
        ++ + H    F       Y+PH+S+LY  LT+ EK K  + A  LD  + GL+F + R+AL+ TD +   + SW K+ E+ L
Subjt:  VDISSHCCRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNL

Sequences

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CDS sequence

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ATGGCGAACCCAACCGAACAATCTGAAGAGCAGAAGAACGTGTATTCTGTGTGGGCTCTTCCTCCAGAAGATGTGGCTGTCAGAATCGAGACTCTGATGAGCGGCCTCAG
ATCCGAGTTCAGGGGGCCCCAATTCGAGCCACACATCACCGTCGTTGGGGCAATCCCTCTCACCCGAGACGACGCCCTCATCAAATTCCGCACCGCTTGCGAGGGGCGTA
AGGCTTATCAAGCCACCGTCGATCATGTGGCCACTGGAACCTTCTTCTACCAGTGCGTTTTTCTCCTAATTCGTCCTACGCCTGAGGTCGTGGATATTAGTTCACACTGC
TGCAGAATTTTTGGTTATAAGAACTCTACCCCCTACATGCCGCATTTGAGCCTACTGTATGCGCACTTAACAGATGAAGAAAAGACGAAGGTGAAAGATATAGCGGACAA
ATTGGATGAAGGGATTACTGGCCTGAGCTTCCCAGTTACCCGACTTGCATTGTACAAAACAGACACCGAAGATGAAACTCTAGAGTCCTGGGAGAAAATTACTGAATACA
ATCTTCGTTTAAGTTAG

mRNA sequence

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GCCGGTGGGATGGGATCGAGTGCCAAAATTTCCCCCTTTTTCCTGAGTACACGTGACCATAAGCCCGTAACCGAAGCAACTTAACAAATATCCATCCAGAACGACATGTC
GACCAAGTGTTTTTTTCCCCTTCCTCAAGTCACAAACAATCACTGCTACTGCCATCGTCATCGTCCTCGAAATCAAAACCTCCCCAAAATTCTCACAACGGTTTGGTCAA
CGCCAATTGCTTTATCAAACAGAAATCGAACCCCAACTTTATCACTCCGTTGCATTTTCGGCTTCTCTTCTGATCTGCTCCGGCTCTGATGGCGAACCCAACCGAACAAT
CTGAAGAGCAGAAGAACGTGTATTCTGTGTGGGCTCTTCCTCCAGAAGATGTGGCTGTCAGAATCGAGACTCTGATGAGCGGCCTCAGATCCGAGTTCAGGGGGCCCCAA
TTCGAGCCACACATCACCGTCGTTGGGGCAATCCCTCTCACCCGAGACGACGCCCTCATCAAATTCCGCACCGCTTGCGAGGGGCGTAAGGCTTATCAAGCCACCGTCGA
TCATGTGGCCACTGGAACCTTCTTCTACCAGTGCGTTTTTCTCCTAATTCGTCCTACGCCTGAGGTCGTGGATATTAGTTCACACTGCTGCAGAATTTTTGGTTATAAGA
ACTCTACCCCCTACATGCCGCATTTGAGCCTACTGTATGCGCACTTAACAGATGAAGAAAAGACGAAGGTGAAAGATATAGCGGACAAATTGGATGAAGGGATTACTGGC
CTGAGCTTCCCAGTTACCCGACTTGCATTGTACAAAACAGACACCGAAGATGAAACTCTAGAGTCCTGGGAGAAAATTACTGAATACAATCTTCGTTTAAGTTAGCTTCC
GATTCTGTTTCTGTTTTTGTTTTTGTTTTTGTTTGGCCCTTTTAAGAGTGTCCTGTTACTTGGTTTATCGTCTTTTCGACAATGTTTCTACTCCTGTAGACTTGTTAACT
GATGAAAATAAAAGTTAGCCCAACCTGTTGTTGATATTGGAAAAAT

Protein sequence

Show/hide protein sequence

MANPTEQSEEQKNVYSVWALPPEDVAVRIETLMSGLRSEFRGPQFEPHITVVGAIPLTRDDALIKFRTACEGRKAYQATVDHVATGTFFYQCVFLLIRPTPEVVDISSHC
CRIFGYKNSTPYMPHLSLLYAHLTDEEKTKVKDIADKLDEGITGLSFPVTRLALYKTDTEDETLESWEKITEYNLRLS

MC01g1505 (gene) of Bitter gourd (Dali-11) v1 genome