CuGenDBv2

Gene ID	MC02g0243
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	Cyclin-dependent kinases regulatory subunit
Genome location	MC02:2288561..2289503
RNA-Seq Expression	MC02g0243
Synteny	MC02g0243
Gene Ontology terms	GO:0007346 - regulation of mitotic cell cycle (biological process) GO:0045737 - positive regulation of cyclin-dependent protein serine/threonine kinase activity (biological process) GO:0051301 - cell division (biological process) GO:0000307 - cyclin-dependent protein kinase holoenzyme complex (cellular component) GO:0019005 - SCF ubiquitin ligase complex (cellular component) GO:0016301 - kinase activity (molecular function) GO:0019901 - protein kinase binding (molecular function) GO:0042393 - histone binding (molecular function) GO:0043130 - ubiquitin binding (molecular function) GO:0061575 - cyclin-dependent protein serine/threonine kinase activator activity (molecular function)
InterPro domains	IPR000789 - Cyclin-dependent kinase, regulatory subunit IPR036858 - Cyclin-dependent kinase, regulatory subunit superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

XP_018833709.1 cyclin-dependent kinases regulatory subunit 1 [Juglans regia]

1.74e-55

95.45

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQEN AQQNV+ K
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

XP_022140304.1 cyclin-dependent kinases regulatory subunit 1-like [Momordica charantia]

3.11e-58

100

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
        MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

XP_038902899.1 cyclin-dependent kinases regulatory subunit 1-like [Benincasa hispida]

1.08e-56

97.7

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVA
        MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNV+A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVA

XP_039002563.1 cyclin-dependent kinases regulatory subunit 1-like [Hibiscus syriacus]

2.11e-56

95.45

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQENLAQQN+VAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

XP_040993547.1 cyclin-dependent kinases regulatory subunit 1 [Juglans microcarpa x Juglans regia]

1.22e-55

95.45

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQEN AQQN++AK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

TrEMBL top hits

e value

%identity

Alignment

A0A2I4FPX3 Cyclin-dependent kinases regulatory subunit

8.41e-56

95.45

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQEN AQQNV+ K
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

A0A6A3D0T7 Cyclin-dependent kinases regulatory subunit

1.02e-56

95.45

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQENLAQQN+VAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

A0A6J1CFB5 Cyclin-dependent kinases regulatory subunit

1.50e-58

100

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
        MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

A0A6J1H322 Cyclin-dependent kinases regulatory subunit

8.67e-56

95.4

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVA
        MGQIQYSEKYFDD YEYRHVVLPP+VAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNV+A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVA

A0A6J1K8L9 Cyclin-dependent kinases regulatory subunit

8.67e-56

95.4

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVA
        MGQIQYSEKYFDD YEYRHVVLPP+VAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNV+A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVA

SwissProt top hits

e value

%identity

Alignment

A2XCH8 Cyclin-dependent kinases regulatory subunit 1

1.2e-39

93.83

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLN+QQQQE  A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA

O23249 Cyclin-dependent kinases regulatory subunit 1

3.8e-41

90.7

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVV
        MGQIQYSEKYFDD +EYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQEN AQ  +V
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVV

P55933 Probable cyclin-dependent kinases regulatory subunit

1.1e-27

78.79

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Query:  IQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRR
        IQYSEKY+DD +EYRHV+LPP+VAK +PK+RLLSE EWR +GVQQS+GWVHYA+HRPEPHI+LFRR
Subjt:  IQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRR

Q6PS57 Cyclin-dependent kinases regulatory subunit 1

1.2e-39

93.83

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLN+QQQQE  A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA

Q9SJJ5 Cyclin-dependent kinases regulatory subunit 2

4.4e-37

88.46

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE
        MGQIQYS+KYFDD +EYRHVVLPPEVAKLLPK+R+LSE+EWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQ+ +
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE

Arabidopsis top hits

e value

%identity

Alignment

AT2G27960.1 cyclin-dependent kinase-subunit 1

2.7e-42

90.7

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVV
        MGQIQYSEKYFDD +EYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQEN AQ  +V
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVV

AT2G27970.1 CDK-subunit 2

3.1e-38

88.46

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE
        MGQIQYS+KYFDD +EYRHVVLPPEVAKLLPK+R+LSE+EWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQ+ +
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE

Sequences

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CDS sequence

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ATGGGTCAGATTCAGTACTCTGAGAAGTACTTTGACGACATTTACGAGTATAGGCATGTGGTGCTCCCACCCGAAGTGGCAAAGTTACTTCCTAAGAGTCGCCTGCTCTC
TGAAAATGAGTGGCGTGCAATTGGAGTTCAGCAGAGTCGTGGGTGGGTGCACTATGCTATTCATCGTCCCGAGCCGCATATCATGCTATTCAGGAGGCCCCTGAACTACC
AACAGCAACAGGAGAACCTTGCCCAACAAAACGTTGTTGCTAAA

mRNA sequence

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Protein sequence

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MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQNVVAK

MC02g0243 (gene) of Bitter gourd (Dali-11) v1 genome