CuGenDBv2

Gene ID	MC04g0684
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	DNA mismatch repair protein MLH3 isoform X1
Genome location	MC04:6465774..6466160
RNA-Seq Expression	MC04g0684
Synteny	MC04g0684
Gene Ontology terms	GO:0006298 - mismatch repair (biological process) GO:0009734 - auxin-activated signaling pathway (biological process) GO:0055085 - transmembrane transport (biological process) GO:0016021 - integral component of membrane (cellular component) GO:0032300 - mismatch repair complex (cellular component) GO:0005524 - ATP binding (molecular function) GO:0016887 - ATPase activity (molecular function) GO:0030983 - mismatched DNA binding (molecular function)
InterPro domains	IPR028830 - DNA mismatch repair protein Mlh3 IPR038973 - DNA mismatch repair protein MutL/Mlh/Pms

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6596281.1 DNA mismatch repair protein MLH3, partial [Cucurbita argyrosperma subsp. sororia]

4.21e-39

83.33

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEG
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ+RE+E+ +KNGSNGTWHGL++HELS+ER LQH+ SAEG
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEG

KAG7027832.1 DNA mismatch repair protein MLH3, partial [Cucurbita argyrosperma subsp. argyrosperma]

1.29e-37

82.93

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSA
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ+RE+E+ +KNGSNGTWHGL++HELS+ER LQH+ SA
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSA

XP_016900665.1 PREDICTED: DNA mismatch repair protein MLH3 isoform X3 [Cucumis melo]

2.39e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

XP_016900669.1 PREDICTED: DNA mismatch repair protein MLH3 isoform X4 [Cucumis melo]

2.38e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

XP_016900671.1 PREDICTED: DNA mismatch repair protein MLH3 isoform X8 [Cucumis melo]

2.36e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BJQ0 DNA mismatch repair protein MLH3 isoform X1

1.16e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

A0A1S3BKL4 DNA mismatch repair protein MLH3 isoform X2

1.16e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

A0A1S4DXF8 DNA mismatch repair protein MLH3 isoform X4

1.15e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

A0A1S4DXG1 DNA mismatch repair protein MLH3 isoform X8

1.14e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

A0A1S4DXG5 DNA mismatch repair protein MLH3 isoform X3

1.16e-37

82.35

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL
        MFGDSLLPSECSLIVEELKQT LCFQC H RPTTVPLVNLEALHKQ++ELE+  K+GSNGTW+GL +HELS+ER LQ LSSAEGL
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

SwissProt top hits

e value

%identity

Alignment

F4JN26 DNA mismatch repair protein MLH3

2.7e-20

59.04

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAE
        MFGDSLLPSECSLI++ LKQT LCFQC H RPTTVPLV+L+ALHKQ+ +L           WHGLQ+ E++L+R    L +A+
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAE

Arabidopsis top hits

e value

%identity

Alignment

AT4G35520.1 MUTL protein homolog 3

1.9e-21

59.04

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Query:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAE
        MFGDSLLPSECSLI++ LKQT LCFQC H RPTTVPLV+L+ALHKQ+ +L           WHGLQ+ E++L+R    L +A+
Subjt:  MFGDSLLPSECSLIVEELKQT-LCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAE

Sequences

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CDS sequence

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ATGTTTGGAGACTCTTTGTTACCTTCAGAATGTTCCCTCATTGTTGAAGAACTAAAGCAGACTCTGTGTTTCCAATGTACCCATGCACGACCCACGACAGTACCTCTTGT
GAACTTGGAGGCCTTGCACAAGCAGTTAAGGGAGCTGGAAGTATCAAACAAAAATGGTTCAAATGGAACATGGCATGGGCTGCAGCAACACGAGCTGAGCCTTGAACGGA
CATTGCAGCACTTAAGTTCAGCCGAAGGTTTA

mRNA sequence

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Protein sequence

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MFGDSLLPSECSLIVEELKQTLCFQCTHARPTTVPLVNLEALHKQLRELEVSNKNGSNGTWHGLQQHELSLERTLQHLSSAEGL

MC04g0684 (gene) of Bitter gourd (Dali-11) v1 genome