CuGenDBv2

Gene ID	MC06g1102
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	Aha1_N domain-containing protein
Genome location	MC06:11503164..11508105
RNA-Seq Expression	MC06g1102
Synteny	MC06g1102
Gene Ontology terms	GO:0006457 - protein folding (biological process) GO:0032781 - positive regulation of ATPase activity (biological process) GO:0005829 - cytosol (cellular component) GO:0001671 - ATPase activator activity (molecular function) GO:0051087 - chaperone binding (molecular function) GO:0051879 - Hsp90 protein binding (molecular function)
InterPro domains	IPR015310 - Activator of Hsp90 ATPase, N-terminal IPR036338 - Activator of Hsp90 ATPase, Aha1 IPR039981 - Activator of 90kDa heat shock protein ATPase-like

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_011660198.1 uncharacterized protein LOC101207721 [Cucumis sativus]

5.80e-126

92.04

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Query:  MENG-AVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK
        MENG AVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELL+SVASLEFSSGKAEIADVSK
Subjt:  MENG-AVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        CVGDAFLVTVRNKKRVGYTYELTLK+KGEWTIR+EKKTVKG IDVPEFSFGELDDLQM+VRLSEE+DLL EDK ++CQDLKRFLQPVREQLLQFEQELKE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

XP_022157075.1 uncharacterized protein LOC111023885 [Momordica charantia]

3.42e-136

100

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

XP_022933923.1 uncharacterized protein LOC111441189 [Cucurbita moschata]

9.28e-125

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VGDAFLVTVRNKKRVGYTYELTLK+KGEWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQDLKRFLQPVR +LLQFEQELKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

XP_022973883.1 uncharacterized protein LOC111472472 [Cucurbita maxima]

9.28e-125

90.5

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMK+LLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VGDAFLVTVRNKKRVGYTYELTLK+KGEWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQD KRFLQPVRE+LLQFEQELKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

XP_038878257.1 uncharacterized protein LOC120070542 [Benincasa hispida]

2.88e-126

92.54

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Query:  MENG-AVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK
        MENG AVSSETQQGASYTYWVREARKDAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELLMSVASLEFS+GKAEIADVSK
Subjt:  MENG-AVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        CVGDAFLVTVRNKKRVGYTYE TLK+KGEWTIR+EKK VKG IDVPEFSFGELDDLQM+VRLSEEKDLL EDKL++CQDLKRFLQPVRE+LLQFEQELKE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

TrEMBL top hits

e value

%identity

Alignment

A0A0A0M014 Aha1_N domain-containing protein

2.81e-126

92.04

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Query:  MENG-AVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK
        MENG AVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELL+SVASLEFSSGKAEIADVSK
Subjt:  MENG-AVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        CVGDAFLVTVRNKKRVGYTYELTLK+KGEWTIR+EKKTVKG IDVPEFSFGELDDLQM+VRLSEE+DLL EDK ++CQDLKRFLQPVREQLLQFEQELKE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

A0A6J1DS44 uncharacterized protein LOC111023885

1.65e-136

100

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

A0A6J1F676 uncharacterized protein LOC111441189

4.49e-125

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VGDAFLVTVRNKKRVGYTYELTLK+KGEWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQDLKRFLQPVR +LLQFEQELKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

A0A6J1IEG5 uncharacterized protein LOC111472472

4.49e-125

90.5

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMK+LLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VGDAFLVTVRNKKRVGYTYELTLK+KGEWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQD KRFLQPVRE+LLQFEQELKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

A0A6J1JLS1 uncharacterized protein LOC111485576

1.29e-124

90.5

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE RKDAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKN+NKWA+ RMKELLMSVASLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VGDA LVTVRNKKRVGYTYELTLK+KGEWTIR+EKK VKG IDVPEFSFGELD+LQMEVRLSEEKDL+ EDKL++CQDLKRFLQPVRE+L QFEQELKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

SwissProt top hits

e value

%identity

Alignment

O95433 Activator of 90 kDa heat shock protein ATPase homolog 1

6.5e-04

26.17

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Query:  WEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKVKGEWT-IREEKKTVKGDIDVPEFS-FGELDDLQME
        W E++ + W++ ++K L ++V  ++   GK E+ +VSK  G+A   ++ N+K ++ + YE ++K+   WT   +     KG +++P  S    +D++++ 
Subjt:  WEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKVKGEWT-IREEKKTVKGDIDVPEFS-FGELDDLQME

Query:  VRLSEEK
        V L++++
Subjt:  VRLSEEK

Q8BK64 Activator of 90 kDa heat shock protein ATPase homolog 1

2.9e-04

25.4

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Query:  WEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKVKGEWT-IREEKKTVKGDIDVPEFS-FGELDDLQME
        W E++ + W++ ++K L ++V  +E   GK E+ +V+K  G+A   ++ N+K ++ + YE T+K+   WT   +     KG +++P  S    +D++++ 
Subjt:  WEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKVKGEWT-IREEKKTVKGDIDVPEFS-FGELDDLQME

Query:  VRLSEEKD------LLAEDKLRVCQD
        V L++++       L+ ED +++ ++
Subjt:  VRLSEEKD------LLAEDKLRVCQD

Arabidopsis top hits

e value

%identity

Alignment

AT5G58110.1 chaperone binding;ATPase activators

1.2e-66

64.58

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Query:  ETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVT
        +T++G+SY YWVREA  DAAP P+P+KLS  D+  + A  P +LGS+WNRAGTWEEK+L KWA+ R+KELL SV SL+FSSGKAEI DV++CVGDAFLVT
Subjt:  ETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVT

Query:  VRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VRNKKRVGYTYEL+LKV+GEW+  E  K VKG +++PEFSFGELDDL+++V+LSE+K+L  + K R+  D+K+FL+P+R +L  FEQELK+R
Subjt:  VRNKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

Sequences

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CDS sequence

Show/hide CDS sequence

ATGGAGAATGGAGCAGTTTCGTCGGAGACCCAACAGGGGGCGTCCTACACCTATTGGGTCAGGGAAGCGCGGAAGGACGCCGCCCCACTTCCTGTCCCTCGCAAGCTCTC
CGCTGAGGACATTGTCGCTTCTCAAGCGTCTCAGCCTCCTACCCTTGGCTCCGTCTGGAATCGGGCTGGAACATGGGAGGAGAAGAACTTGAATAAATGGGCGAGTGGTA
GAATGAAGGAGTTGCTAATGTCAGTGGCTTCCTTGGAGTTCTCCAGCGGTAAAGCAGAGATAGCGGATGTATCAAAATGTGTTGGAGATGCTTTTTTAGTGACTGTACGT
AACAAGAAACGTGTTGGTTATACATATGAACTTACATTGAAAGTTAAAGGTGAGTGGACTATTAGAGAGGAGAAGAAGACGGTGAAGGGGGATATAGATGTCCCAGAATT
TTCATTTGGTGAGCTAGATGACTTGCAGATGGAAGTGAGATTGAGCGAAGAGAAGGATCTTCTGGCTGAGGATAAGTTGCGGGTTTGCCAAGATTTGAAACGGTTTTTGC
AGCCTGTTCGCGAACAGTTGCTTCAATTCGAACAGGAACTCAAAGAAAGATAA

mRNA sequence

Show/hide mRNA sequence

CAAGACTGACAAATTCCTTAAATATGGGCCTTAAATAAAGGTCTAGGTCCGGCCCAAATGGTCTCTCATAGGTCCACCAGCGAGAGAGGGCGAAGAGGGGAAAGAAGAAC
GTTCGAGAAGAGTGAGGTTGAATCTCGTCGTCGCGTCGTAGCGCCATTTCTTCAAAAATCCTGCATCTCCCACGAAATTCAAAATCCACAGGAAGTTTCGTGCGAAGAGG
CGTCGTCACATTACAGATCTCCTTCGTCTTCTCATTCAAACTTGGCGTGCGCTGCGCTTGTTCGAATCAATCAATCAATCAATCAGGTACAATCTCTGTTCTGTGATTAT
CGGAACAACAAGCTCGGCGATGGAGAATGGAGCAGTTTCGTCGGAGACCCAACAGGGGGCGTCCTACACCTATTGGGTCAGGGAAGCGCGGAAGGACGCCGCCCCACTTC
CTGTCCCTCGCAAGCTCTCCGCTGAGGACATTGTCGCTTCTCAAGCGTCTCAGCCTCCTACCCTTGGCTCCGTCTGGAATCGGGCTGGAACATGGGAGGAGAAGAACTTG
AATAAATGGGCGAGTGGTAGAATGAAGGAGTTGCTAATGTCAGTGGCTTCCTTGGAGTTCTCCAGCGGTAAAGCAGAGATAGCGGATGTATCAAAATGTGTTGGAGATGC
TTTTTTAGTGACTGTACGTAACAAGAAACGTGTTGGTTATACATATGAACTTACATTGAAAGTTAAAGGTGAGTGGACTATTAGAGAGGAGAAGAAGACGGTGAAGGGGG
ATATAGATGTCCCAGAATTTTCATTTGGTGAGCTAGATGACTTGCAGATGGAAGTGAGATTGAGCGAAGAGAAGGATCTTCTGGCTGAGGATAAGTTGCGGGTTTGCCAA
GATTTGAAACGGTTTTTGCAGCCTGTTCGCGAACAGTTGCTTCAATTCGAACAGGAACTCAAAGAAAGATAAAAGGTGCTTTCCTCTCAATATGTACTAATTATAATTGT
ACTTTCAAACTGTTGATTGGCAAGAATGTCTTATTGGATTCCTTTAGGCTTTCACGGATCATAATTTATGAACAGAACAGCATTTTTAAGCTGGCAGCCCTTGAGATGCT
GAAATTGTAATACATCTAAATAACTGATTTGTTGTGGGAAGTTAAACTCTTGAATGTTTCAGGTAGTTTGAGGGCCTGCTATTATTTTTTATTAGGTCCCTTGGAAACAA
GTCTGCTATATGTCGTGTTAGTGGGATGATATTTTTAATTCATTTGGATGGATATTCTCTCGTCAATAGGGACAATTTTAGTAAGAACTTATCTAAATAACATTATCGAA
GCGAAGAACATA

Protein sequence

Show/hide protein sequence

MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVR
NKKRVGYTYELTLKVKGEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

MC06g1102 (gene) of Bitter gourd (Dali-11) v1 genome