CuGenDBv2

Gene ID	MC06g1781
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	Aspartic proteinase nepenthesin-2-like
Genome location	MC06:25090863..25091328
RNA-Seq Expression	MC06g1781
Synteny	MC06g1781
Gene Ontology terms	GO:0006508 - proteolysis (biological process) GO:0004190 - aspartic-type endopeptidase activity (molecular function)
InterPro domains	IPR001461 - Aspartic peptidase A1 family

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7034471.1 Aspartic proteinase nepenthesin-1, partial [Cucurbita argyrosperma subsp. argyrosperma]

8.35e-35

48.92

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Query:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------
        MEF  IP  FL S  +  S SS+SS+TT+TLPLT F SL F                   H   PRT++N +     L   SYGAYS+ L+FG       
Subjt:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------

Query:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK
              SSLVWFPCTA + C  CSFP V  ATI KFIPKLSS+AKIIG    KC+WIFGPN+K  C + +    +CSDTCPGYGI+
Subjt:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK

TYK07446.1 aspartic proteinase nepenthesin-2-like [Cucumis melo var. makuwa]

1.10e-34

47.03

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Query:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------
        MEFLPIP  FLFS  +   +S+SS+  ITLPLT F S+ F                   H   P++++N +    +L   SYGAY+V L+FG        
Subjt:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------

Query:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK
             SSLVWFPCTA + C  CSFP V  ATI+KF+PKLSS+ KI+G    KCAWIFGPN+K RC N      +CSD+CPGYGI+
Subjt:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK

XP_011657732.1 probable aspartyl protease At4g16563 [Cucumis sativus]

7.77e-36

47.03

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Query:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------
        MEFLPIP  FLFS  +   +S+SS+TT+ LPLT F S+ F                   H   P++++N +    +L   SYGAYSV L+FG        
Subjt:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------

Query:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK
             SSLVWFPCTA + C RCSFP V  ATI+KF+PKLSS+ K++G    KCAWIFGPN+K RC N      +CSD+CPGYG++
Subjt:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK

XP_022925946.1 probable aspartyl protease At4g16563 [Cucurbita moschata]

4.29e-35

48.92

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Query:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------
        MEF  IP  FL S  +  S SS+SS+TT+TLPLT F SL F                   H   PRT++N +     L   SYGAYS+ L+FG       
Subjt:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------

Query:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK
              SSLVWFPCTA + C  CSFP V  ATI KFIPKLSS+AKIIG    KC+WIFGPN+K  C + +    +CSDTCPGYGI+
Subjt:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK

XP_023543736.1 probable aspartyl protease At4g16563 [Cucurbita pepo subsp. pepo]

1.13e-35

48.92

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Query:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------
        MEF PIP  FL S  +  S SS+SS+TT+TLPLT F SL F                   H   PR ++N +     L   SYGAYS+ L+FG       
Subjt:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------

Query:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK
              SSLVWFPCTA + C  CSFP V  ATI KFIPKLSS+AKIIG    KC+WIFGPN+K  C + +    +CSDTCPGYGI+
Subjt:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KHK2 Peptidase A1 domain-containing protein

3.76e-36

47.03

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Query:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------
        MEFLPIP  FLFS  +   +S+SS+TT+ LPLT F S+ F                   H   P++++N +    +L   SYGAYSV L+FG        
Subjt:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------

Query:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK
             SSLVWFPCTA + C RCSFP V  ATI+KF+PKLSS+ K++G    KCAWIFGPN+K RC N      +CSD+CPGYG++
Subjt:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK

A0A1S3CHV2 aspartic proteinase nepenthesin-2-like

2.82e-34

46.49

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Query:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------
        MEFLPIP  FLFS  +   +S+SS+  ITLPL  F S+ F                   H   P++++N +    +L   SYGAY+V L+FG        
Subjt:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------

Query:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK
             SSLVWFPCTA + C  CSFP V  ATI+KF+PKLSS+ KI+G    KCAWIFGPN+K RC N      +CSD+CPGYGI+
Subjt:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK

A0A5A7SGF9 Aspartic proteinase nepenthesin-2-like

2.82e-34

46.49

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Query:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------
        MEFLPIP  FLFS  +   +S+SS+  ITLPL  F S+ F                   H   P++++N +    +L   SYGAY+V L+FG        
Subjt:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------

Query:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK
             SSLVWFPCTA + C  CSFP V  ATI+KF+PKLSS+ KI+G    KCAWIFGPN+K RC N      +CSD+CPGYGI+
Subjt:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK

A0A5D3CAS4 Aspartic proteinase nepenthesin-2-like

5.34e-35

47.03

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Query:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------
        MEFLPIP  FLFS  +   +S+SS+  ITLPLT F S+ F                   H   P++++N +    +L   SYGAY+V L+FG        
Subjt:  MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG--------

Query:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK
             SSLVWFPCTA + C  CSFP V  ATI+KF+PKLSS+ KI+G    KCAWIFGPN+K RC N      +CSD+CPGYGI+
Subjt:  -----SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNA-VLILECSDTCPGYGIK

A0A6J1EDJ0 probable aspartyl protease At4g16563

2.08e-35

48.92

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Query:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------
        MEF  IP  FL S  +  S SS+SS+TT+TLPLT F SL F                   H   PRT++N +     L   SYGAYS+ L+FG       
Subjt:  MEFLPIPIPFLFSYSIA-STSSASSNTTITLPLTAFSSLEFQI-----------------HGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFG-------

Query:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK
              SSLVWFPCTA + C  CSFP V  ATI KFIPKLSS+AKIIG    KC+WIFGPN+K  C + +    +CSDTCPGYGI+
Subjt:  ------SSLVWFPCTAHFLCFRCSFP-VAIATITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWN-AVLILECSDTCPGYGIK

SwissProt top hits	e value	%identity	Alignment
No hits found

Arabidopsis top hits

e value

%identity

Alignment

AT3G52500.1 Eukaryotic aspartyl protease family protein

2.1e-13

44.55

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Query:  SYGAYSVFLSF-------------GSSLVWFPCTAHFLCFRCSFPVAIAT-ITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNAVLILECSDTCPG
        SYG YSV LSF             GSSLVW PCT+ +LC  C F     T I +FIPK SS++KIIG    KC +++GPNV+ R  +      C+  CP 
Subjt:  SYGAYSVFLSF-------------GSSLVWFPCTAHFLCFRCSFPVAIAT-ITKFIPKLSSAAKIIGYGKWKCAWIFGPNVKFRCWNAVLILECSDTCPG

Query:  Y
        Y
Subjt:  Y

Sequences

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CDS sequence

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ATGGAATTCCTTCCCATTCCGATTCCCTTTCTATTTTCATATTCCATTGCTTCTACTTCCTCTGCTTCCTCTAACACCACCATCACACTCCCCCTCACCGCCTTCTCTTC
TCTCGAGTTCCAGATCCATGGAAATGGTCCAAGAACCGAAACAAATCAAGCGCATTCGCCGAGAAATTTGCTCACGTGTAGCTATGGCGCTTACTCAGTTTTTCTCAGCT
TCGGAAGTAGTCTCGTCTGGTTCCCCTGCACCGCCCATTTTCTCTGCTTCAGGTGTTCGTTTCCGGTGGCTATTGCGACGATTACGAAATTTATCCCCAAATTATCTTCT
GCTGCGAAGATTATCGGTTACGGAAAGTGGAAATGTGCTTGGATTTTTGGCCCTAATGTGAAATTTAGATGTTGGAATGCCGTCTTAATTCTTGAATGTTCCGATACGTG
TCCTGGTTATGGAATTAAG

mRNA sequence

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Protein sequence

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MEFLPIPIPFLFSYSIASTSSASSNTTITLPLTAFSSLEFQIHGNGPRTETNQAHSPRNLLTCSYGAYSVFLSFGSSLVWFPCTAHFLCFRCSFPVAIATITKFIPKLSS
AAKIIGYGKWKCAWIFGPNVKFRCWNAVLILECSDTCPGYGIK

MC06g1781 (gene) of Bitter gourd (Dali-11) v1 genome