CuGenDBv2

Gene ID	MC08g0936
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	phosphatidyl-N-methylethanolamine N-methyltransferase
Genome location	MC08:7509657..7512427
RNA-Seq Expression	MC08g0936
Synteny	MC08g0936
Gene Ontology terms	GO:0006656 - phosphatidylcholine biosynthetic process (biological process) GO:0032259 - methylation (biological process) GO:0005789 - endoplasmic reticulum membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0000773 - phosphatidyl-N-methylethanolamine N-methyltransferase activity (molecular function) GO:0004608 - phosphatidylethanolamine N-methyltransferase activity (molecular function) GO:0080101 - phosphatidyl-N-dimethylethanolamine N-methyltransferase activity (molecular function)
InterPro domains	IPR007318 - Phospholipid methyltransferase IPR024960 - Phosphatidyl-N-methylethanolamine/Phosphatidylethanolamine N-methyltransferase

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7036543.1 Phosphatidyl-N-methylethanolamine N-methyltransferase [Cucurbita argyrosperma subsp. argyrosperma]

4.00e-107

89.02

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M ++A IGVLLPFP+YYVLWTRPQLW N CGKW EP KLMA+VS+FLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYI+DPQYVGSILS+ ACLSWVPLQYILL T+GYVFMMQVESKED TTRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

XP_004137657.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis sativus]

5.68e-107

89.02

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGI A IGVLLPFP+YYVLW RPQLW N CGK REPCKLMA+VS+FLKLLQFLSI+HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYI+DPQYVGSILS+FACLSWVPL+YILL TLGY+FMM VESKED  TRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

XP_008465151.2 PREDICTED: phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis melo]

8.41e-109

89.63

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGI+A IGVLLPFP+YYVLW RPQLW N CGK REPCKLMA+VS+FLKLLQFLSI+HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYI+DPQYVGSILS+FACLSWVPL+YILL TLGY+FMM VESKEDP TRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

XP_022153398.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Momordica charantia]

2.17e-120

100

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

XP_023523751.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Cucurbita pepo subsp. pepo]

1.15e-106

88.41

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M ++A IGVLLPFP+YYVLWTRPQLW N CGKW EP KLMA+VS+FLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYI+DPQYVGSILS+ ACLSWVPLQYILL T+GYVFMMQVESKED TTRAKPQ+
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CPQ5 phosphatidyl-N-methylethanolamine N-methyltransferase

4.07e-109

89.63

Show/hide

Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGI+A IGVLLPFP+YYVLW RPQLW N CGK REPCKLMA+VS+FLKLLQFLSI+HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYI+DPQYVGSILS+FACLSWVPL+YILL TLGY+FMM VESKEDP TRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

A0A1U8H4P5 Phosphatidyl-N-methylethanolamine N-methyltransferase

1.23e-94

78.05

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG++A +GV+LPFPFYY LWTRPQ W + CG+ R+PCK+MA  S F+KLLQF+S+L VS+FSWPPPLYFWPL  FGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFG IRDPQYVGSILS+ ACLSWVP  YILL  LGYVFM+QVESKEDP TRAKP S
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

A0A6J1DHC8 phosphatidyl-N-methylethanolamine N-methyltransferase

1.05e-120

100

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

A0A6J1GCG7 phosphatidyl-N-methylethanolamine N-methyltransferase

1.59e-106

88.41

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M ++A IGVLLPFP+YYVLWTRPQLW N CGKW EP KLMA+VS+FLKLLQ LSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYI+DPQYVGSILS+ ACLSWVPLQYILL T+GYVFMMQVESKED TTRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

A0A6J1KB80 phosphatidyl-N-methylethanolamine N-methyltransferase

5.55e-107

88.41

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M ++A IGVLLPFP+YY+LWTRPQLW N CGKW EP KLMA+VS+FLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS
        NIPWVTEFPFGYI+DPQYVGSILS+ ACLSWVPLQYILL T+GYVFMMQVESKED TTRAKPQS
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

SwissProt top hits

e value

%identity

Alignment

Q9SAH5 Phosphatidyl-N-methylethanolamine N-methyltransferase

3.2e-69

75.78

Show/hide

Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG++A IGVLLPFPFY+ LWT  Q W N CG+ R+P  +MARVS  LK  Q LS+  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAK
        NIPWVTEFPFG IRDPQYVGSI+S+ ACLSWVP QYILL +LGYVFMM +ESKEDP  RAK
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAK

Arabidopsis top hits

e value

%identity

Alignment

AT1G80860.1 phospholipid N-methyltransferase

2.2e-70

75.78

Show/hide

Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG++A IGVLLPFPFY+ LWT  Q W N CG+ R+P  +MARVS  LK  Q LS+  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAK
        NIPWVTEFPFG IRDPQYVGSI+S+ ACLSWVP QYILL +LGYVFMM +ESKEDP  RAK
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAK

AT1G80860.2 phospholipid N-methyltransferase

2.2e-70

75.78

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Query:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG++A IGVLLPFPFY+ LWT  Q W N CG+ R+P  +MARVS  LK  Q LS+  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAK
        NIPWVTEFPFG IRDPQYVGSI+S+ ACLSWVP QYILL +LGYVFMM +ESKEDP  RAK
Subjt:  NIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAK

Sequences

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CDS sequence

Show/hide CDS sequence

GGGGATCATTTTCCCGAGAAAGTGGAGGAATCCGGTGAGAAAAATATCAGAATCAGAATCAGAATGGGCATAATCGCAGGAATTGGAGTGCTGCTGCCATTTCCCTTCTA
CTACGTCTTATGGACTCGTCCACAGTTATGGGCGAATTTTTGCGGGAAATGGCGCGAACCCTGCAAATTGATGGCTCGGGTCTCCATCTTTCTCAAGTTGCTTCAGTTCC
TCTCCATCCTCCACGTCTCCTCCTTCTCATGGCCGCCGCCTCTCTACTTCTGGCCCCTCATGGCCTTTGGCCAATTTTTGAACTTCAGGGTCTATCAGTTACTGGGTGAA
TCCGGTGTTTACTATGGAGTACGGTTTGGGAAGAACATTCCATGGGTGACAGAATTTCCATTTGGATATATAAGAGATCCTCAGTATGTGGGAAGCATTTTGAGCATTTT
TGCTTGTCTTTCTTGGGTACCCTTGCAATATATTCTGCTGTTGACGCTGGGATACGTCTTTATGATGCAAGTTGAATCAAAGGAAGATCCCACAACTCGGGCAAAGCCTC
AAAGT

mRNA sequence

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Protein sequence

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GDHFPEKVEESGEKNIRIRIRMGIIAGIGVLLPFPFYYVLWTRPQLWANFCGKWREPCKLMARVSIFLKLLQFLSILHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE
SGVYYGVRFGKNIPWVTEFPFGYIRDPQYVGSILSIFACLSWVPLQYILLLTLGYVFMMQVESKEDPTTRAKPQS

MC08g0936 (gene) of Bitter gourd (Dali-11) v1 genome