CuGenDBv2

Gene ID	MC08g2219
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	CST complex subunit TEN1-like
Genome location	MC08:30996100..31000468
RNA-Seq Expression	MC08g2219
Synteny	MC08g2219
Gene Ontology terms	GO:0006457 - protein folding (biological process) GO:0009408 - response to heat (biological process) GO:0019827 - stem cell population maintenance (biological process) GO:0032211 - negative regulation of telomere maintenance via telomerase (biological process) GO:0048367 - shoot system development (biological process) GO:0051974 - negative regulation of telomerase activity (biological process) GO:1990879 - CST complex (cellular component) GO:0003697 - single-stranded DNA binding (molecular function) GO:0010521 - telomerase inhibitor activity (molecular function) GO:0042162 - telomeric DNA binding (molecular function) GO:0044183 - protein folding chaperone (molecular function)
InterPro domains	IPR029146 - CST complex subunit Ten1, animal and plant type

Homology

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GenBank top hits

e value

%identity

Alignment

XP_022156372.1 CST complex subunit TEN1 isoform X1 [Momordica charantia]

1.50e-80

100

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
        MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI

Query:  DLNLYHQSLQLLRQFQADHFNKRTN
        DLNLYHQSLQLLRQFQADHFNKRTN
Subjt:  DLNLYHQSLQLLRQFQADHFNKRTN

XP_022937765.1 CST complex subunit TEN1 [Cucurbita moschata]

2.69e-74

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
        MAS+AIKSGALV LKDLKPSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNV+LKIDT+HLREL+FRIGSIYQFIGELLVQS+NEATLQARVGRNVDGI
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI

Query:  DLNLYHQSLQLLRQFQADHFNKRTN
        DLNLYHQSLQLL+QFQADH NKRTN
Subjt:  DLNLYHQSLQLLRQFQADHFNKRTN

XP_022966009.1 CST complex subunit TEN1-like [Cucurbita maxima]

6.61e-75

92.8

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
        MAS+AIKSGALV LKDLKPSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNV+LKIDTQHLREL+FRIGSIYQFIGELLVQS+NEATLQARVGRNVDGI
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI

Query:  DLNLYHQSLQLLRQFQADHFNKRTN
        DLNLYHQSLQLL+QFQADH NKRTN
Subjt:  DLNLYHQSLQLLRQFQADHFNKRTN

XP_023536947.1 CST complex subunit TEN1-like [Cucurbita pepo subsp. pepo]

1.62e-75

93.6

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
        MAS+AIKSGALV LKDLKPSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNV+LKIDTQHLREL+FRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI

Query:  DLNLYHQSLQLLRQFQADHFNKRTN
        DLNLYHQSLQLL+QFQADH NKRTN
Subjt:  DLNLYHQSLQLLRQFQADHFNKRTN

XP_038889106.1 CST complex subunit TEN1 isoform X2 [Benincasa hispida]

7.98e-74

93.65

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Query:  MASSAIKSGALVPLKDL-KPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDG
        MAS+AIKSGALV LKDL KPSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNVNLKIDTQHLRELS RIGSIYQFIGELLVQSDNEATL+ARVGRNVDG
Subjt:  MASSAIKSGALVPLKDL-KPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDG

Query:  IDLNLYHQSLQLLRQFQADHFNKRTN
        IDLNLYHQSLQLLRQFQADH NKRTN
Subjt:  IDLNLYHQSLQLLRQFQADHFNKRTN

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LFY0 Uncharacterized protein

1.24e-70

91.27

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Query:  MASSAIKSGALVPLKDLK-PSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDG
        MA SAIKSGALV LKDL  PSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNVNLKIDTQHL ELS RIGSIYQFIGELLVQSDNEA L+ARVGRNVDG
Subjt:  MASSAIKSGALVPLKDLK-PSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDG

Query:  IDLNLYHQSLQLLRQFQADHFNKRTN
        IDLNLYHQSLQLLRQFQADH NKRTN
Subjt:  IDLNLYHQSLQLLRQFQADHFNKRTN

A0A1S3BY71 CST complex subunit TEN1

2.24e-73

93.65

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Query:  MASSAIKSGALVPLKDL-KPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDG
        MA SAIKSGALV LKDL KPSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNVNLKIDTQHLRELS RIGSIYQFIGELLVQSDNEA LQARVGRNVDG
Subjt:  MASSAIKSGALVPLKDL-KPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDG

Query:  IDLNLYHQSLQLLRQFQADHFNKRTN
        IDLNLYHQSLQLLRQFQADH NKRTN
Subjt:  IDLNLYHQSLQLLRQFQADHFNKRTN

A0A6J1DRX0 CST complex subunit TEN1 isoform X1

7.28e-81

100

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
        MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI

Query:  DLNLYHQSLQLLRQFQADHFNKRTN
        DLNLYHQSLQLLRQFQADHFNKRTN
Subjt:  DLNLYHQSLQLLRQFQADHFNKRTN

A0A6J1FHR1 CST complex subunit TEN1

1.30e-74

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
        MAS+AIKSGALV LKDLKPSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNV+LKIDT+HLREL+FRIGSIYQFIGELLVQS+NEATLQARVGRNVDGI
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI

Query:  DLNLYHQSLQLLRQFQADHFNKRTN
        DLNLYHQSLQLL+QFQADH NKRTN
Subjt:  DLNLYHQSLQLLRQFQADHFNKRTN

A0A6J1HSH0 CST complex subunit TEN1-like

3.20e-75

92.8

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI
        MAS+AIKSGALV LKDLKPSSEFFKDGASLRVTGKLVEYSVETA+A+IVDGNV+LKIDTQHLREL+FRIGSIYQFIGELLVQS+NEATLQARVGRNVDGI
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGI

Query:  DLNLYHQSLQLLRQFQADHFNKRTN
        DLNLYHQSLQLL+QFQADH NKRTN
Subjt:  DLNLYHQSLQLLRQFQADHFNKRTN

SwissProt top hits

e value

%identity

Alignment

Q6NME7 CST complex subunit TEN1

1.2e-32

59.84

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGEL-LVQSDNEATLQARVGRNVDG
        MA S I+ G  + L++L PSS F+K+G SLRVT  L  YSVETA+ VI DG  +LKI+TQ++R++SFR+GSIYQFIGEL + Q +NEA LQAR GRNVDG
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGEL-LVQSDNEATLQARVGRNVDG

Query:  IDLNLYHQSLQLLRQFQADHFN
        ID+NLY ++++LLRQF  +  N
Subjt:  IDLNLYHQSLQLLRQFQADHFN

Arabidopsis top hits

e value

%identity

Alignment

AT1G56260.1 unknown protein

8.7e-34

59.84

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Query:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGEL-LVQSDNEATLQARVGRNVDG
        MA S I+ G  + L++L PSS F+K+G SLRVT  L  YSVETA+ VI DG  +LKI+TQ++R++SFR+GSIYQFIGEL + Q +NEA LQAR GRNVDG
Subjt:  MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGEL-LVQSDNEATLQARVGRNVDG

Query:  IDLNLYHQSLQLLRQFQADHFN
        ID+NLY ++++LLRQF  +  N
Subjt:  IDLNLYHQSLQLLRQFQADHFN

Sequences

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CDS sequence

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ATGGCATCGTCTGCAATAAAATCAGGGGCATTAGTTCCATTAAAAGATCTGAAGCCATCTTCTGAGTTCTTCAAGGATGGAGCCTCACTTAGAGTTACTGGAAAACTAGT
GGAGTATTCTGTAGAGACAGCCATGGCCGTAATCGTTGATGGAAATGTTAACTTGAAGATCGACACCCAGCATCTGAGAGAACTTAGCTTTCGCATTGGCTCTATATATC
AATTTATTGGTGAACTACTTGTTCAATCAGATAATGAGGCAACTCTGCAGGCACGTGTAGGCAGGAATGTTGACGGCATTGACCTCAACCTTTATCATCAGTCCCTGCAG
CTGTTAAGACAATTTCAGGCTGATCACTTCAACAAGAGGACAAATTAG

mRNA sequence

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TTTCGAAGTCATAATTTGTCGTCTCGTCACTGACTCACTGTGTCGCTCGGTTTGGAGCTTGGGAGGTCGAACAAGGATTTGACCTGCAGTAGAAATCAGAGTGCTTTTTG
TGAGAAAGAGGATTTTACTGGATGGCATCGTCTGCAATAAAATCAGGGGCATTAGTTCCATTAAAAGATCTGAAGCCATCTTCTGAGTTCTTCAAGGATGGAGCCTCACT
TAGAGTTACTGGAAAACTAGTGGAGTATTCTGTAGAGACAGCCATGGCCGTAATCGTTGATGGAAATGTTAACTTGAAGATCGACACCCAGCATCTGAGAGAACTTAGCT
TTCGCATTGGCTCTATATATCAATTTATTGGTGAACTACTTGTTCAATCAGATAATGAGGCAACTCTGCAGGCACGTGTAGGCAGGAATGTTGACGGCATTGACCTCAAC
CTTTATCATCAGTCCCTGCAGCTGTTAAGACAATTTCAGGCTGATCACTTCAACAAGAGGACAAATTAGTTCACTTTTAGCCTTGGGGAGAATCTCTCGTATGTTTCACC
GACAGAGATTTCATCAGTCCATGTTTTTTCCAATGGAATTTTAGTTGGTGACAAAGAGCCTACAACTCAGAACCTATGAATCTTGAATTAGGTTGATTAGGCATAGGCCA
ATAGGAATACTTAACCAACCCACTTGAGTTCATAGCTCTGTTGACCAAATTTATAATTACTATGCAAATTGTATTCTAGTGTGTAGCTTGTTCTTGTGGTGTCTAATCCT
TGTAATCAAAACTCTTCCAAATTTGTCAAATTTTGTGTGCAAATTATTCCCAAGTAATTATGAGCCAACCAATTTGAAG

Protein sequence

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MASSAIKSGALVPLKDLKPSSEFFKDGASLRVTGKLVEYSVETAMAVIVDGNVNLKIDTQHLRELSFRIGSIYQFIGELLVQSDNEATLQARVGRNVDGIDLNLYHQSLQ
LLRQFQADHFNKRTN

MC08g2219 (gene) of Bitter gourd (Dali-11) v1 genome