CuGenDBv2

Gene ID	MC09g0498
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	Transmembrane amino acid transporter family protein
Genome location	MC09:4536698..4537050
RNA-Seq Expression	MC09g0498
Synteny	MC09g0498
Gene Ontology terms	GO:0006865 - amino acid transport (biological process) GO:0009734 - auxin-activated signaling pathway (biological process) GO:0055085 - transmembrane transport (biological process) GO:0005886 - plasma membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0015293 - symporter activity (molecular function)
InterPro domains	IPR013057 - Amino acid transporter, transmembrane domain

Homology

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GenBank top hits

e value

%identity

Alignment

XP_022147778.1 amino acid transporter AVT1A-like isoform X1 [Momordica charantia]

2.09e-46

79.03

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSK+AVWTTV +P     +LMNPLARSI+E LP  ISDSYW  ILLRTTLV SS+ VAFLLPF GLVMALIGSF+SILVAVIIPTMCFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISATL
        REATKMQ +SSI++IGLGI SATL
Subjt:  REATKMQSSSSISIIGLGIISATL

XP_022941259.1 amino acid transporter AVT1A-like isoform X2 [Cucurbita moschata]

2.43e-39

71.31

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVAVWTTV +P     +LMNPLARSI+E LP  IS+S+W  ILLRT LVVSS+CVAFLLPF GLVMALIGS +SIL+AVI+P +CFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         EA+KMQ + S  IIGLG++SA
Subjt:  REATKMQSSSSISIIGLGIISA

XP_022971193.1 amino acid transporter AVT1A-like isoform X2 [Cucurbita maxima]

2.43e-39

71.31

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVAVWTTV +P     +LMNPLARSI+E LP  IS+S+W  ILLRT LVVSS+CVAFLLPF GLVMALIGS +SIL+AVI+P +CFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         EA+KMQ + S  IIGLG++SA
Subjt:  REATKMQSSSSISIIGLGIISA

XP_023539401.1 amino acid transporter AVT1A-like isoform X2 [Cucurbita pepo subsp. pepo]

2.43e-39

71.31

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVAVWTTV +P     +LMNPLARSI+E LP  IS+S+W  ILLRT LVVSS+CVAFLLPF GLVMALIGS +SIL+AVI+P +CFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         EA+KMQ + S  IIGLG++SA
Subjt:  REATKMQSSSSISIIGLGIISA

XP_031738577.1 amino acid transporter AVT1A isoform X2 [Cucumis sativus]

2.63e-39

69.67

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVA WTTV +P     +LMNPLARSI+E LPP IS SY   ILLRT LV SS+CVAF+LPF GLVM+LIGS +SILV+VI+PTMC+LKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         +ATK+Q +SSI ++GLGI+SA
Subjt:  REATKMQSSSSISIIGLGIISA

TrEMBL top hits

e value

%identity

Alignment

A0A6J1D210 amino acid transporter AVT1A-like isoform X1

1.01e-46

79.03

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSK+AVWTTV +P     +LMNPLARSI+E LP  ISDSYW  ILLRTTLV SS+ VAFLLPF GLVMALIGSF+SILVAVIIPTMCFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISATL
        REATKMQ +SSI++IGLGI SATL
Subjt:  REATKMQSSSSISIIGLGIISATL

A0A6J1FMR2 amino acid transporter AVT1A-like isoform X1

1.30e-39

71.31

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVAVWTTV +P     +LMNPLARSI+E LP  IS+S+W  ILLRT LVVSS+CVAFLLPF GLVMALIGS +SIL+AVI+P +CFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         EA+KMQ + S  IIGLG++SA
Subjt:  REATKMQSSSSISIIGLGIISA

A0A6J1FMS3 amino acid transporter AVT1A-like isoform X2

1.18e-39

71.31

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVAVWTTV +P     +LMNPLARSI+E LP  IS+S+W  ILLRT LVVSS+CVAFLLPF GLVMALIGS +SIL+AVI+P +CFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         EA+KMQ + S  IIGLG++SA
Subjt:  REATKMQSSSSISIIGLGIISA

A0A6J1I1A7 amino acid transporter AVT1A-like isoform X1

1.30e-39

71.31

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Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVAVWTTV +P     +LMNPLARSI+E LP  IS+S+W  ILLRT LVVSS+CVAFLLPF GLVMALIGS +SIL+AVI+P +CFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         EA+KMQ + S  IIGLG++SA
Subjt:  REATKMQSSSSISIIGLGIISA

A0A6J1I648 amino acid transporter AVT1A-like isoform X2

1.18e-39

71.31

Show/hide

Query:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKHAVTSKVAVWTTV +P     +LMNPLARSI+E LP  IS+S+W  ILLRT LVVSS+CVAFLLPF GLVMALIGS +SIL+AVI+P +CFLKI+G
Subjt:  NMPKHAVTSKVAVWTTV-SP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPF-GLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISA
         EA+KMQ + S  IIGLG++SA
Subjt:  REATKMQSSSSISIIGLGIISA

SwissProt top hits

e value

%identity

Alignment

F4IUW3 Amino acid transporter AVT1C

2.2e-15

41.13

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Query:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG
        N+P+  + +K+AVWTTV        + ++P+A S++E +P     S+WY I +RT LV S++ V   +P FGLVM+LIGS +++LV +I+P  CFL IV 
Subjt:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISATL
        R+ T  Q    + II +G IS+ +
Subjt:  REATKMQSSSSISIIGLGIISATL

F4JE35 Amino acid transporter AVT1B

7.0e-14

36.29

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Query:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG
        N+P+  V SK+A+WTTV        + ++P+A S++E +P     S +Y I +R+ L +S++ V   +P FGLVM+LIGSF+++L+ +I+P  CFL I+ 
Subjt:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISATL
        ++ T  Q +  I I+ +G + + +
Subjt:  REATKMQSSSSISIIGLGIISATL

O80668 Amino acid transporter AVT1A

4.6e-26

56.45

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Query:  NMPKHAVTSKVAVWTT-VSP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG
        NMP+    SKVA WTT VSP     +LMNPLARSI+E LP  +S++ W  +LLRT LV SS+C AFL+P FGL+MALIGS +SILVA+I+P +CF+KI+G
Subjt:  NMPKHAVTSKVAVWTT-VSP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISATL
         +AT+ Q   S  I+ +G++S TL
Subjt:  REATKMQSSSSISIIGLGIISATL

Q8GYS4 Amino acid transporter AVT1D

5.9e-13

42.98

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Query:  NMPKHAVTSKVAVWTTV-SPM-----LMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKH   SKVAVWT V +PM      + P+  S++E +P     S    IL RT LV S++ VA  +P F +V ALIGSF+++LVA+I P +C+L I+ 
Subjt:  NMPKHAVTSKVAVWTTV-SPM-----LMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIIS
         + +  Q    I II  G++S
Subjt:  REATKMQSSSSISIIGLGIIS

Q8LPF4 Amino acid transporter AVT1E

9.4e-11

39.84

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Query:  NMPKHAVTSKVAVWT-TVSPM-----LMNPLARSIQEQLPPIISD--SYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKI
        NMP H  +SK+AVWT  V+PM      + P+  S++E +P       S    +L RT LV+S++ VA  +P F  V ALIGSFI++L+A+I P +C++ I
Subjt:  NMPKHAVTSKVAVWT-TVSPM-----LMNPLARSIQEQLPPIISD--SYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKI

Query:  VGREATKMQSSSSISIIGLGIIS
        +    T  Q    I I+ +GI+S
Subjt:  VGREATKMQSSSSISIIGLGIIS

Arabidopsis top hits

e value

%identity

Alignment

AT2G39130.1 Transmembrane amino acid transporter family protein

1.5e-16

41.13

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Query:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG
        N+P+  + +K+AVWTTV        + ++P+A S++E +P     S+WY I +RT LV S++ V   +P FGLVM+LIGS +++LV +I+P  CFL IV 
Subjt:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISATL
        R+ T  Q    + II +G IS+ +
Subjt:  REATKMQSSSSISIIGLGIISATL

AT2G41190.1 Transmembrane amino acid transporter family protein

3.3e-27

56.45

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Query:  NMPKHAVTSKVAVWTT-VSP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG
        NMP+    SKVA WTT VSP     +LMNPLARSI+E LP  +S++ W  +LLRT LV SS+C AFL+P FGL+MALIGS +SILVA+I+P +CF+KI+G
Subjt:  NMPKHAVTSKVAVWTT-VSP-----MLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIISATL
         +AT+ Q   S  I+ +G++S TL
Subjt:  REATKMQSSSSISIIGLGIISATL

AT3G09340.1 Transmembrane amino acid transporter family protein

1.3e-10

36.89

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Query:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIIS-DSYWYCILLRTTLVVSSICVAFLLPFGLVM-ALIGSFISILVAVIIPTMCFLKIV
        NMP+    SK+AVWT V        + + P+   ++E +PP     SY   I ++T LV+S++ VA   PF  +M AL+GSF++ LV  I P +C+L I+
Subjt:  NMPKHAVTSKVAVWTTV------SPMLMNPLARSIQEQLPPIIS-DSYWYCILLRTTLVVSSICVAFLLPFGLVM-ALIGSFISILVAVIIPTMCFLKIV

Query:  GREATKMQSSSSISIIGLGIIS
            +K Q    + II  GI+S
Subjt:  GREATKMQSSSSISIIGLGIIS

AT5G02170.1 Transmembrane amino acid transporter family protein

6.7e-12

39.84

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Query:  NMPKHAVTSKVAVWT-TVSPM-----LMNPLARSIQEQLPPIISD--SYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKI
        NMP H  +SK+AVWT  V+PM      + P+  S++E +P       S    +L RT LV+S++ VA  +P F  V ALIGSFI++L+A+I P +C++ I
Subjt:  NMPKHAVTSKVAVWT-TVSPM-----LMNPLARSIQEQLPPIISD--SYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKI

Query:  VGREATKMQSSSSISIIGLGIIS
        +    T  Q    I I+ +GI+S
Subjt:  VGREATKMQSSSSISIIGLGIIS

AT5G02180.1 Transmembrane amino acid transporter family protein

4.2e-14

42.98

Show/hide

Query:  NMPKHAVTSKVAVWTTV-SPM-----LMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG
        NMPKH   SKVAVWT V +PM      + P+  S++E +P     S    IL RT LV S++ VA  +P F +V ALIGSF+++LVA+I P +C+L I+ 
Subjt:  NMPKHAVTSKVAVWTTV-SPM-----LMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLP-FGLVMALIGSFISILVAVIIPTMCFLKIVG

Query:  REATKMQSSSSISIIGLGIIS
         + +  Q    I II  G++S
Subjt:  REATKMQSSSSISIIGLGIIS

Sequences

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CDS sequence

Show/hide CDS sequence

AACATGCCAAAACACGCTGTTACCTCTAAAGTTGCAGTGTGGACAACAGTTTCACCAATGTTGATGAATCCGTTGGCAAGAAGTATACAGGAGCAACTACCGCCTATAAT
TTCAGATAGCTACTGGTATTGCATTCTTCTAAGAACAACACTTGTTGTTTCTTCTATTTGCGTAGCTTTCCTTCTGCCCTTTGGCCTTGTGATGGCTTTAATTGGCTCAT
TTATCAGCATACTTGTGGCGGTAATAATACCAACAATGTGTTTTTTAAAAATCGTGGGAAGGGAAGCTACAAAGATGCAGAGCAGTTCGAGCATCTCCATTATCGGGCTG
GGCATCATTAGCGCAACCCTC

mRNA sequence

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Protein sequence

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NMPKHAVTSKVAVWTTVSPMLMNPLARSIQEQLPPIISDSYWYCILLRTTLVVSSICVAFLLPFGLVMALIGSFISILVAVIIPTMCFLKIVGREATKMQSSSSISIIGL
GIISATL

MC09g0498 (gene) of Bitter gourd (Dali-11) v1 genome