; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; CuGenDBv2

MS000058 (gene) of Bitter gourd (TR) v1 genome

Gene IDMS000058
OrganismMomordica charantia cv. TR (Bitter gourd (TR) v1)
DescriptionDNA topoisomerase
Genome locationscaffold946_1:539085..539317
RNA-Seq ExpressionMS000058
SyntenyMS000058
Gene Ontology termsGO:0006265 - DNA topological change (biological process)
GO:0005634 - nucleus (cellular component)
GO:0003676 - nucleic acid binding (molecular function)
GO:0003916 - DNA topoisomerase activity (molecular function)
GO:0046872 - metal ion binding (molecular function)
InterPro domainsNA


Homology Show/hide homology
GenBank top hitse value%identityAlignment
XP_008443145.1 PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cucumis melo]3.5e-1164.71Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NM++TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
XP_022154286.1 DNA topoisomerase 3-alpha [Momordica charantia]7.0e-1260.71Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLI----------------AVLFHASIRKF
        VAEK SVAKAVATI+SRNQGLR R  R R NKIF FNYAIRG   NML+TSVTG+L+                A LFHA +RKF
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLI----------------AVLFHASIRKF
XP_022934066.1 DNA topoisomerase 3-alpha isoform X1 [Cucurbita moschata]3.5e-1166.18Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NML+TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
XP_022934067.1 DNA topoisomerase 3-alpha isoform X2 [Cucurbita moschata]3.5e-1166.18Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NML+TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
XP_023526238.1 DNA topoisomerase 3-alpha isoform X1 [Cucurbita pepo subsp. pepo]3.5e-1166.18Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NML+TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
TrEMBL top hitse value%identityAlignment
A0A5A7TKA3 DNA topoisomerase1.7e-1164.71Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NM++TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
A0A5D3DP88 DNA topoisomerase1.7e-1164.71Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NM++TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
A0A6J1DNA0 DNA topoisomerase3.4e-1260.71Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLI----------------AVLFHASIRKF
        VAEK SVAKAVATI+SRNQGLR R  R R NKIF FNYAIRG   NML+TSVTG+L+                A LFHA +RKF
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLI----------------AVLFHASIRKF
A0A6J1IXM8 DNA topoisomerase1.7e-1166.18Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NML+TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
A0A6J1J603 DNA topoisomerase1.7e-1166.18Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VATI+SRNQGLR R  R R NKIF FNYAIRG   NML+TSVTG+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
SwissProt top hitse value%identityAlignment
C7J0A2 DNA topoisomerase 3-alpha3.2e-0746.43Show/hide
Query:  VAEKLSVAKAVATIISR-NQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLI----------------AVLFHASIRK
        VAEK SVAK+VA I+SR + G+R R  R R N++F F+Y+I G   +ML+TSVTG+L+                A LFHA +RK
Subjt:  VAEKLSVAKAVATIISR-NQGLRFR-ARYRNNKIFVFNYAIRGCLANMLITSVTGNLI----------------AVLFHASIRK
O70157 DNA topoisomerase 3-alpha9.6e-0437.31Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFRARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK   AK +A ++S  +  R     + NKI+ F+Y + G    M++TSV+G+L+A  F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFRARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
Q9LVP1 DNA topoisomerase 3-alpha9.2e-0750.75Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFRARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VA I+SR        R R NKIF F+YAI G    ML+TSV G+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFRARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
Arabidopsis top hitse value%identityAlignment
AT5G63920.1 topoisomerase 3alpha6.6e-0850.75Show/hide
Query:  VAEKLSVAKAVATIISRNQGLRFRARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF
        VAEK SVAK+VA I+SR        R R NKIF F+YAI G    ML+TSV G+L+ + F    RK+
Subjt:  VAEKLSVAKAVATIISRNQGLRFRARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF

Sequences Show/hide sequences
CDS sequenceShow/hide CDS sequence
CATGGGAACAACTTCCTCCTTGAAACCATTGTAGCAGAGAAGCTGTCGGTGGCGAAAGCTGTGGCCACCATAATCTCTAGGAACCAAGGCTTGCGATTTCGTGCTCGCTA
TCGCAACAACAAGATTTTCGTGTTCAATTACGCCATTCGAGGGTGTCTTGCCAACATGCTCATCACCTCTGTTACAGGCAATCTCATAGCAGTTCTCTTCCATGCTTCCA
TTCGCAAATTT
mRNA sequenceShow/hide mRNA sequence
CATGGGAACAACTTCCTCCTTGAAACCATTGTAGCAGAGAAGCTGTCGGTGGCGAAAGCTGTGGCCACCATAATCTCTAGGAACCAAGGCTTGCGATTTCGTGCTCGCTA
TCGCAACAACAAGATTTTCGTGTTCAATTACGCCATTCGAGGGTGTCTTGCCAACATGCTCATCACCTCTGTTACAGGCAATCTCATAGCAGTTCTCTTCCATGCTTCCA
TTCGCAAATTT
Protein sequenceShow/hide protein sequence
HGNNFLLETIVAEKLSVAKAVATIISRNQGLRFRARYRNNKIFVFNYAIRGCLANMLITSVTGNLIAVLFHASIRKF