CuGenDBv2

Gene ID	MS005121
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	Cyclin-dependent kinases regulatory subunit
Genome location	scaffold176:2828141..2829085
RNA-Seq Expression	MS005121
Synteny	MS005121
Gene Ontology terms	GO:0007346 - regulation of mitotic cell cycle (biological process) GO:0045737 - positive regulation of cyclin-dependent protein serine/threonine kinase activity (biological process) GO:0051301 - cell division (biological process) GO:0000307 - cyclin-dependent protein kinase holoenzyme complex (cellular component) GO:0019005 - SCF ubiquitin ligase complex (cellular component) GO:0016301 - kinase activity (molecular function) GO:0019901 - protein kinase binding (molecular function) GO:0042393 - histone binding (molecular function) GO:0043130 - ubiquitin binding (molecular function) GO:0061575 - cyclin-dependent protein serine/threonine kinase activator activity (molecular function)
InterPro domains	IPR000789 - Cyclin-dependent kinase, regulatory subunit IPR036858 - Cyclin-dependent kinase, regulatory subunit superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

XP_022140304.1 cyclin-dependent kinases regulatory subunit 1-like [Momordica charantia]

8.8e-43

98.86

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQ+VVAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

XP_038894383.1 cyclin-dependent kinases regulatory subunit 1 [Benincasa hispida]

3.7e-41

94.32

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQEN AQQ ++AK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

XP_038902899.1 cyclin-dependent kinases regulatory subunit 1-like [Benincasa hispida]

1.3e-41

96.55

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVA
        MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQ+V+A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVA

XP_039002563.1 cyclin-dependent kinases regulatory subunit 1-like [Hibiscus syriacus]

2.2e-41

94.32

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQENLAQQ++VAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

XP_040993547.1 cyclin-dependent kinases regulatory subunit 1 [Juglans microcarpa x Juglans regia]

8.2e-41

94.32

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQEN AQQ+++AK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

TrEMBL top hits

e value

%identity

Alignment

A0A068UEM1 Cyclin-dependent kinases regulatory subunit

4.0e-41

95.45

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQEN AQQ VVAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

A0A6A3D0T7 Cyclin-dependent kinases regulatory subunit

1.1e-41

94.32

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQENLAQQ++VAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

A0A6J1CFB5 Cyclin-dependent kinases regulatory subunit

4.3e-43

98.86

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQ+VVAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

A0A6J1K8L9 Cyclin-dependent kinases regulatory subunit

5.2e-41

94.25

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVA
        MGQIQYSEKYFDD YEYRHVVLPP+VAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQ+V+A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVA

A0A6P6VV35 Cyclin-dependent kinases regulatory subunit

4.0e-41

95.45

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQEN AQQ VVAK
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

SwissProt top hits

e value

%identity

Alignment

A2XCH8 Cyclin-dependent kinases regulatory subunit 1

1.2e-39

93.83

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLN+QQQQE  A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA

O23249 Cyclin-dependent kinases regulatory subunit 1

3.8e-41

90.7

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVV
        MGQIQYSEKYFDD +EYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQEN AQ  +V
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVV

P55933 Probable cyclin-dependent kinases regulatory subunit

1.4e-27

78.79

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Query:  IQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRR
        IQYSEKY+DD +EYRHV+LPP+VAK +PK+RLLSE EWR +GVQQS+GWVHYA+HRPEPHI+LFRR
Subjt:  IQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRR

Q6PS57 Cyclin-dependent kinases regulatory subunit 1

1.2e-39

93.83

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA
        MGQIQYSEKYFDD YEYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLN+QQQQE  A
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLA

Q9SJJ5 Cyclin-dependent kinases regulatory subunit 2

4.4e-37

88.46

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE
        MGQIQYS+KYFDD +EYRHVVLPPEVAKLLPK+R+LSE+EWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQ+ +
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE

Arabidopsis top hits

e value

%identity

Alignment

AT2G27960.1 cyclin-dependent kinase-subunit 1

2.7e-42

90.7

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVV
        MGQIQYSEKYFDD +EYRHVVLPPEVAKLLPK+RLLSENEWRAIGVQQSRGWVHYA+HRPEPHIMLFRRPLNYQQQQEN AQ  +V
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVV

AT2G27970.1 CDK-subunit 2

3.1e-38

88.46

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Query:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE
        MGQIQYS+KYFDD +EYRHVVLPPEVAKLLPK+R+LSE+EWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQ+ +
Subjt:  MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQE

Sequences

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CDS sequence

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ATGGGTCAGATTCAGTACTCTGAGAAGTACTTTGACGACATTTACGAGTATAGGCATGTGGTGCTCCCACCCGAAGTGGCAAAGTTACTTCCTAAGAGTCGCCTGCTCTC
TGAAAATGAGTGGCGTGCAATTGGAGTTCAGCAGAGTCGTGGGTGGGTGCACTATGCTATTCATCGTCCCGAGCCGCATATCATGCTATTCAGGAGGCCCCTGAACTACC
AACAGCAACAGGAGAACCTTGCCCAACAACACGTTGTTGCTAAA

mRNA sequence

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Protein sequence

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MGQIQYSEKYFDDIYEYRHVVLPPEVAKLLPKSRLLSENEWRAIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYQQQQENLAQQHVVAK

MS005121 (gene) of Bitter gourd (TR) v1 genome