CuGenDBv2

Gene ID	MS010407
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	dCTP pyrophosphatase 1
Genome location	scaffold878:690162..690646
RNA-Seq Expression	MS010407
Synteny	MS010407
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR004518 - NTP pyrophosphohydrolase MazG, putative catalytic core IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0049237.1 dCTP pyrophosphatase 1-like [Cucumis melo var. makuwa]

1.8e-48

89.38

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Query:  MGGSEQL---DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDA
        MGG +Q+   DISLKDLSLKL EFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEES+KEHLGEELSDVLLYLIRLADICGINL++A
Subjt:  MGGSEQL---DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDA

Query:  AAKKLVKNSIKYP
        A KKLVKNSIKYP
Subjt:  AAKKLVKNSIKYP

XP_004134058.1 dCTP pyrophosphatase 1 [Cucumis sativus]

5.2e-48

86.32

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Query:  MGGSEQL-------DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGIN
        MGG +Q+       DISLKDLSLKL EFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEES+KEHLGEELSDVLLYLIRLADICGIN
Subjt:  MGGSEQL-------DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGIN

Query:  LSDAAAKKLVKNSIKYP
        L++AA KKLVKNSIKYP
Subjt:  LSDAAAKKLVKNSIKYP

XP_022151675.1 dCTP pyrophosphatase 1-like [Momordica charantia]

2.3e-56

100

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Query:  MGGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAK
        MGGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAK
Subjt:  MGGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAK

Query:  KLVKNSIKYPPQ
        KLVKNSIKYPPQ
Subjt:  KLVKNSIKYPPQ

XP_022924788.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

4.3e-50

89.66

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Query:  MGGSEQ-----LDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS
        MGGSEQ     +DISLKDLS KL EFAK RNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEES+KEHLGEELSDVLLYLIRLADICGINL 
Subjt:  MGGSEQ-----LDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS

Query:  DAAAKKLVKNSIKYPP
        DAA KKLVKNSIKYPP
Subjt:  DAAAKKLVKNSIKYPP

XP_038878506.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

7.3e-50

88.03

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Query:  MGGSEQL-----DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS
        MGG +Q+     DISLKDLS KL EFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEES+KEHLGEELSDVLLYLIRLADICGINL 
Subjt:  MGGSEQL-----DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS

Query:  DAAAKKLVKNSIKYPPQ
        DAA KKL+KNSIKYPPQ
Subjt:  DAAAKKLVKNSIKYPPQ

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L514 dCTP pyrophosphatase 1

2.5e-48

86.32

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Query:  MGGSEQL-------DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGIN
        MGG +Q+       DISLKDLSLKL EFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEES+KEHLGEELSDVLLYLIRLADICGIN
Subjt:  MGGSEQL-------DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGIN

Query:  LSDAAAKKLVKNSIKYP
        L++AA KKLVKNSIKYP
Subjt:  LSDAAAKKLVKNSIKYP

A0A5A7U4H7 dCTP pyrophosphatase 1

8.6e-49

89.38

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Query:  MGGSEQL---DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDA
        MGG +Q+   DISLKDLSLKL EFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEES+KEHLGEELSDVLLYLIRLADICGINL++A
Subjt:  MGGSEQL---DISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDA

Query:  AAKKLVKNSIKYP
        A KKLVKNSIKYP
Subjt:  AAKKLVKNSIKYP

A0A6J1DBU8 dCTP pyrophosphatase 1

1.1e-56

100

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Query:  MGGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAK
        MGGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAK
Subjt:  MGGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAK

Query:  KLVKNSIKYPPQ
        KLVKNSIKYPPQ
Subjt:  KLVKNSIKYPPQ

A0A6J1EDH1 dCTP pyrophosphatase 1

2.1e-50

89.66

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Query:  MGGSEQ-----LDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS
        MGGSEQ     +DISLKDLS KL EFAK RNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEES+KEHLGEELSDVLLYLIRLADICGINL 
Subjt:  MGGSEQ-----LDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS

Query:  DAAAKKLVKNSIKYPP
        DAA KKLVKNSIKYPP
Subjt:  DAAAKKLVKNSIKYPP

A0A6J1IR36 dCTP pyrophosphatase 1

2.1e-50

89.66

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Query:  MGGSEQ-----LDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS
        MGGSEQ     +DISLKDLS KL EFAK RNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEES+KEHLGEELSDVLLYLIRLADICGINL 
Subjt:  MGGSEQ-----LDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLS

Query:  DAAAKKLVKNSIKYPP
        DAA KKLVKNSIKYPP
Subjt:  DAAAKKLVKNSIKYPP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

2.5e-21

48.51

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Query:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W   E+  L EELSD+L+YL+ LA  C ++L  A   K+  N  +Y
Subjt:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY

Query:  P
        P
Subjt:  P

Q91VC0 dCTP pyrophosphatase 1

2.3e-22

49.5

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Query:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W+  E+  L EELSDVL+YL+ LA  C ++L  A   K+  N  +Y
Subjt:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY

Query:  P
        P
Subjt:  P

Q9H773 dCTP pyrophosphatase 1

4.3e-21

49.5

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Query:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W   E+  L EELSDVL+YL+ LA  C ++L  A   K+  N  +Y
Subjt:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY

Query:  P
        P
Subjt:  P

Q9QY93 dCTP pyrophosphatase 1

3.0e-22

49.5

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Query:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W   E+  L EELSDVL+YL+ LA  C ++L  A   K+  N  +Y
Subjt:  SLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKY

Query:  P
        P
Subjt:  P

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

2.9e-41

69.72

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Query:  GGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKK
        GG ++  +SL+ LS K+ +FAKAR+WEKYHSPRNLLLAMVGEVGELSEIFQW+GEV +G PDW+E EK HLGEELSDVLLYL+RL+D CG++L  AA +K
Subjt:  GGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKK

Query:  LVKNSIKYP
        +  N+IKYP
Subjt:  LVKNSIKYP

Sequences

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CDS sequence

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ATGGGAGGGAGCGAGCAGCTGGACATTAGCCTCAAGGACCTGTCTTTGAAGCTCCACGAGTTCGCCAAGGCCAGGAATTGGGAGAAGTATCACAGCCCTAGAAACCTTCT
CCTTGCTATGGTAGGAGAAGTAGGGGAGCTATCAGAAATATTCCAATGGAGAGGGGAGGTGGAGAAAGGGCTGCCAGATTGGGAGGAATCAGAAAAGGAGCATCTTGGGG
AAGAACTTTCTGATGTGTTACTCTATCTTATCAGATTGGCTGATATTTGTGGAATCAACTTATCTGATGCTGCTGCCAAGAAGCTTGTTAAGAACTCCATCAAATACCCA
CCCCAA

mRNA sequence

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Protein sequence

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MGGSEQLDISLKDLSLKLHEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESEKEHLGEELSDVLLYLIRLADICGINLSDAAAKKLVKNSIKYP
PQ

MS010407 (gene) of Bitter gourd (TR) v1 genome