CuGenDBv2

Gene ID	MS012556
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	chloride channel protein CLC-c
Genome location	scaffold63:1519921..1520259
RNA-Seq Expression	MS012556
Synteny	MS012556
Gene Ontology terms	GO:0006821 - chloride transport (biological process) GO:0034220 - ion transmembrane transport (biological process) GO:0016021 - integral component of membrane (cellular component) GO:0005247 - voltage-gated chloride channel activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

TYK00790.1 chloride channel protein CLC-c [Cucumis melo var. makuwa]

5.3e-16

48.39

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Query:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS
        S  KL R   D   E   N  EI+  D     PF+EDRDSV++TL EPLLRT+TARISTTSQLAIVGSN+CPIESLDYE +   L            IF 
Subjt:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS

Query:  ILVASYFLCVCDHVVDDVIFGGFF
         ++  + LC+C  ++  ++  GFF
Subjt:  ILVASYFLCVCDHVVDDVIFGGFF

XP_008452224.1 PREDICTED: LOW QUALITY PROTEIN: chloride channel protein CLC-c [Cucumis melo]

5.3e-16

48.39

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Query:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS
        S  KL R   D   E   N  EI+  D     PF+EDRDSV++TL EPLLRT+TARISTTSQLAIVGSN+CPIESLDYE +   L            IF 
Subjt:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS

Query:  ILVASYFLCVCDHVVDDVIFGGFF
         ++  + LC+C  ++  ++  GFF
Subjt:  ILVASYFLCVCDHVVDDVIFGGFF

XP_022136814.1 chloride channel protein CLC-c [Momordica charantia]

2.4e-29

73.27

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Query:  MDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLC
        MDNHTERDANGGEIEGCDTAAEWPFS+DRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYE +   L            IF  ++  + LC
Subjt:  MDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLC

Query:  V
        +
Subjt:  V

XP_022984849.1 chloride channel protein CLC-c-like isoform X1 [Cucurbita maxima]

3.1e-16

52.73

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Query:  ERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHV
        ER  NG EI+G ++ AE PF+EDRDSV++TL EPLLR +TARISTTSQLAIVGSN+CPIESLDYE +   L            IF  ++  + LC+   +
Subjt:  ERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHV

Query:  VDDVIFGGFF
        +  V+  GFF
Subjt:  VDDVIFGGFF

XP_023552785.1 chloride channel protein CLC-c-like isoform X1 [Cucurbita pepo subsp. pepo]

5.3e-16

53.64

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Query:  ERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHV
        ER  NG E EG ++ AE PF+EDRDSV++TL EPLLR +TARISTTSQLAIVGSNVCPIESLDYE +   L            IF  ++  + LC+   +
Subjt:  ERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHV

Query:  VDDVIFGGFF
        +  V+  GFF
Subjt:  VDDVIFGGFF

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BUH5 LOW QUALITY PROTEIN: chloride channel protein CLC-c

2.6e-16

48.39

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Query:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS
        S  KL R   D   E   N  EI+  D     PF+EDRDSV++TL EPLLRT+TARISTTSQLAIVGSN+CPIESLDYE +   L            IF 
Subjt:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS

Query:  ILVASYFLCVCDHVVDDVIFGGFF
         ++  + LC+C  ++  ++  GFF
Subjt:  ILVASYFLCVCDHVVDDVIFGGFF

A0A5A7V168 Chloride channel protein CLC-c

2.6e-16

48.39

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Query:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS
        S  KL R   D   E   N  EI+  D     PF+EDRDSV++TL EPLLRT+TARISTTSQLAIVGSN+CPIESLDYE +   L            IF 
Subjt:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS

Query:  ILVASYFLCVCDHVVDDVIFGGFF
         ++  + LC+C  ++  ++  GFF
Subjt:  ILVASYFLCVCDHVVDDVIFGGFF

A0A5D3BP18 Chloride channel protein CLC-c

2.6e-16

48.39

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Query:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS
        S  KL R   D   E   N  EI+  D     PF+EDRDSV++TL EPLLRT+TARISTTSQLAIVGSN+CPIESLDYE +   L            IF 
Subjt:  SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFS

Query:  ILVASYFLCVCDHVVDDVIFGGFF
         ++  + LC+C  ++  ++  GFF
Subjt:  ILVASYFLCVCDHVVDDVIFGGFF

A0A6J1C5E7 chloride channel protein CLC-c

1.2e-29

73.27

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Query:  MDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLC
        MDNHTERDANGGEIEGCDTAAEWPFS+DRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYE +   L            IF  ++  + LC
Subjt:  MDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLC

Query:  V
        +
Subjt:  V

A0A6J1JBP4 Chloride channel protein

1.5e-16

52.73

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Query:  ERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHV
        ER  NG EI+G ++ AE PF+EDRDSV++TL EPLLR +TARISTTSQLAIVGSN+CPIESLDYE +   L            IF  ++  + LC+   +
Subjt:  ERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHV

Query:  VDDVIFGGFF
        +  V+  GFF
Subjt:  VDDVIFGGFF

SwissProt top hits

e value

%identity

Alignment

Q96282 Chloride channel protein CLC-c

1.1e-05

47.89

Show/hide

Query:  MDNHTERDANGGEIE-GCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYE
        MD+  E D +  E+E G     E   S   D  +V   +PLL  N  R +TTSQ+AIVG+N CPIESLDYE
Subjt:  MDNHTERDANGGEIE-GCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYE

Arabidopsis top hits

e value

%identity

Alignment

AT5G33280.1 Voltage-gated chloride channel family protein

1.0e-04

37.93

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Query:  PFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHVVDDVI
        P S   DSV V    PLL +     ++TSQ+AIVG+NVCPIESLDYE                  IF  +   + LC C  ++  +I
Subjt:  PFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLL-----------IFSILVASYFLCVCDHVVDDVI

AT5G49890.1 chloride channel C

8.2e-07

47.89

Show/hide

Query:  MDNHTERDANGGEIE-GCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYE
        MD+  E D +  E+E G     E   S   D  +V   +PLL  N  R +TTSQ+AIVG+N CPIESLDYE
Subjt:  MDNHTERDANGGEIE-GCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYE

Sequences

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CDS sequence

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AGTTTCTGTAAACTTCAGAGGGAGCGGATGGATAATCACACTGAGAGGGACGCGAACGGCGGCGAAATCGAGGGGTGCGATACGGCGGCGGAATGGCCGTTCTCCGAGGA
CAGGGATTCTGTAACGGTGACGCTTGAGGAGCCGCTGTTGCGGACCAATACTGCCAGGATTAGTACTACCTCTCAGCTCGCCATTGTTGGTTCTAATGTCTGTCCAATCG
AGAGCCTGGACTACGAGTATGTATATTATGTACTCCTCATCTTTTCAATTCTTGTTGCTTCTTATTTTCTTTGCGTTTGCGATCATGTTGTCGATGATGTGATTTTTGGT
GGTTTTTTT

mRNA sequence

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Protein sequence

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SFCKLQRERMDNHTERDANGGEIEGCDTAAEWPFSEDRDSVTVTLEEPLLRTNTARISTTSQLAIVGSNVCPIESLDYEYVYYVLLIFSILVASYFLCVCDHVVDDVIFG
GFF

MS012556 (gene) of Bitter gourd (TR) v1 genome