CuGenDBv2

Gene ID	MS012957
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	Dihydroorotase
Genome location	scaffold38:904043..904246
RNA-Seq Expression	MS012957
Synteny	MS012957
Gene Ontology terms	GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process (biological process) GO:0044205 - 'de novo' UMP biosynthetic process (biological process) GO:0005737 - cytoplasm (cellular component) GO:0004151 - dihydroorotase activity (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR004721 - Dihydroorotase homodimeric type IPR032466 - Metal-dependent hydrolase

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008443395.1 PREDICTED: dihydroorotase, mitochondrial isoform X2 [Cucumis melo]

1.5e-18

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SAS FGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA KS
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

XP_022144520.1 dihydroorotase, mitochondrial isoform X1 [Momordica charantia]

6.9e-19

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SASNFGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

XP_022144523.1 dihydroorotase, mitochondrial isoform X2 [Momordica charantia]

6.9e-19

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SASNFGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

XP_038897131.1 dihydroorotase, mitochondrial-like isoform X1 [Benincasa hispida]

9.0e-19

73.53

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SASNFGR+IVMPNLKPPITTTAA VAYRD   K + S+ NF+PL+TLYLTDTMSPN+IKLA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

XP_038897132.1 dihydroorotase, mitochondrial-like isoform X2 [Benincasa hispida]

9.0e-19

73.53

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SASNFGR+IVMPNLKPPITTTAA VAYRD   K + S+ NF+PL+TLYLTDTMSPN+IKLA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

TrEMBL top hits

e value

%identity

Alignment

A0A1S3B8N1 Dihydroorotase

7.4e-19

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SAS FGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA KS
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

A0A5A7UFB1 Dihydroorotase

7.4e-19

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SAS FGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA KS
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

A0A5D3DPM6 Dihydroorotase

7.4e-19

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SAS FGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA KS
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

A0A6J1CRV5 Dihydroorotase

3.3e-19

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SASNFGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

A0A6J1CTX5 Dihydroorotase

3.3e-19

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SASNFGR+IVMPNLKPPITTTAA VAYRD   K + S+ NFIPL+TLYLTDTMSPN+IKLA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

SwissProt top hits

e value

%identity

Alignment

A1K3T5 Dihydroorotase

1.9e-11

45.59

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        ++ ++A  FGR+++MPNL+PP+TTTA  +AYRD     V +   F PL++LYLTD  +P++I+ A  S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

C5CMK6 Dihydroorotase

1.4e-11

47.06

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        ++ +SA  FGR++VMPNL+PP+TT A  VAYRD     V     F P+++LYLTD + P +I LA+++
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

O04904 Dihydroorotase, mitochondrial

2.4e-14

54.41

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        ++ +SASNF R+IVMPNLKPP+T+TAA + YR +  K + S  +F PL+TLYLTD   P +I+LA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

Q0JJD1 Dihydroorotase, mitochondrial

7.4e-16

57.35

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        +L +SA +FGR+IVMPNLKPP+TTTA  + YR+   + +    NF+PL+TLYLTD  SP +IKLA KS
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

Q31ZB7 Dihydroorotase

1.4e-11

47.62

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIK
        ++ Y++  +GR+IVMPNL PP+TT  A VAYR      V +  NF PL+T YLTD++ PN+++
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIK

Arabidopsis top hits

e value

%identity

Alignment

AT4G22930.1 pyrimidin 4

1.7e-15

54.41

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Query:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS
        ++ +SASNF R+IVMPNLKPP+T+TAA + YR +  K + S  +F PL+TLYLTD   P +I+LA +S
Subjt:  ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

Sequences

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CDS sequence

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ATATTAATATACAGCGCAAGTAACTTTGGAAGGTCTATCGTGATGCCAAATTTAAAGCCACCCATCACTACAACAGCCGCTGGAGTTGCTTATCGAGATTATTTCTCGAA
ACCAGTGTCTTCTAGTCGCAACTTCATTCCTCTTATTACCCTTTATTTGACAGATACAATGAGCCCTAACAAGATCAAGCTCGCAAGTAAGTCT

mRNA sequence

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Protein sequence

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ILIYSASNFGRSIVMPNLKPPITTTAAGVAYRDYFSKPVSSSRNFIPLITLYLTDTMSPNKIKLASKS

MS012957 (gene) of Bitter gourd (TR) v1 genome