CuGenDBv2

Gene ID	MS014349
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	DNA topoisomerase
Genome location	scaffold19:121210..147328
RNA-Seq Expression	MS014349
Synteny	MS014349
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0003677 - DNA binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function)
InterPro domains	IPR000380 - DNA topoisomerase, type IA IPR003601 - DNA topoisomerase, type IA, domain 2 IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR006171 - TOPRIM domain IPR013497 - DNA topoisomerase, type IA, central IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013825 - DNA topoisomerase, type IA, central region, subdomain 2 IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR023405 - DNA topoisomerase, type IA, core domain IPR023406 - DNA topoisomerase, type IA, active site IPR034144 - DNA topoisomerase 3-like, TOPRIM domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6582102.1 DNA topoisomerase 3-beta, partial [Cucurbita argyrosperma subsp. sororia]

0.0e+00

92.62

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HAHYKVTSVIGH+FSIDFP RFQ+W  TDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGNE+RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDVA MFQKRV EDGI EVT+ISEKQESK RPSGLNTVNLLKVASSALG+GPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSL+KNPEWGDYVR+LLSDGYSKPRSGTD GDHPPITPM LATEDM+GRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  VM KGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIEQQIT VAKGQ DHFSVVQN LQQFKQKYSYFVKKIDHMDALFEAQFSPLA+SGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC TCEEVYYLPQ+G IKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID LYGAAKT  SSG S+KG+GMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPV APNW+LNCNKCN LVFLPQGAHRI+TTN+KC ECDS IIEVDFNKKTTPLE GATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGR RGRGRG GRGR +G+LMDPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF

XP_022137893.1 DNA topoisomerase 3-beta isoform X1 [Momordica charantia]

0.0e+00

99.41

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPP+TPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQR+YCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRS--RGRGRGGRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGRS  RGRGRGGRGRGAGR MDPKMSFRDF
Subjt:  GKSFFRGRGSRGRS--RGRGRGGRGRGAGRLMDPKMSFRDF

XP_022955609.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita moschata]

0.0e+00

92.74

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HAHYKVTSVIGH+FSIDFP RFQ+W  TDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGNE+RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDVA MFQKRV EDGI EVT+ISEKQESK RPSGLNTVNLLKVASSALG+GPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSL+KNPEWGDYVRVLLSDGYSKPRSGTD GDHPPITPM LATEDM+GRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  VM KGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIEQQIT VAKGQ DHFSVVQN LQQFKQKYSYFVKKIDHMDALFEAQFSPLA+SGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC TCEEVYYLPQ+G IKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID LYGAAKT  SSG S+KG+GMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPV APNW+LNCNKCN LVFLPQGAHRI+TTN+KC ECDS IIEVDFNKKTTPLE GATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGR RGRGRG GRGR +G+LMDPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF

XP_022979706.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita maxima]

0.0e+00

92.62

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HAHYKVTSVIGH+FSIDFP RFQ+W  TDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDVA MFQKRV EDGI EVT+ISEKQESK RPSGLNTVNLLKVASSALG+GPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSL+KNPEWGDYVR+LLSDGYSKPRSGTD GDHPPITPM LATEDM+GRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  V+ KGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIEQQIT VAKGQ DHFSVVQN LQQFKQKYSYFVKKIDHMDALFEAQFSPLA+SGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC TCEEVYYLPQ+G IKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKT  SSG S+KG+GMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPV APNW+LNCNKCN LVFLPQGAHRI+TTN+KC ECDS IIEVDFNKKTTPLE GATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGR RGRGRG GRGR +G+LMDPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF

XP_023528530.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita pepo subsp. pepo]

0.0e+00

92.16

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HAHYKVTSVIGH+FSIDFP RFQ+W  TDPLDLFQASVIK ESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGN++RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDVA MFQKRV EDGI EVT+ISEKQESK RPSGLNTVNLLKVASSALG+GPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSL+KNPEWGDYVR+LLSDGYSKPRSGTD GDHPPITPM LATEDM+GRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  VM KGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIEQQIT VAKGQ DHFSVVQN LQQFKQKYSYFVKKIDHMDALFEAQFSPLA+SGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC TCEEVYYLPQ+G IKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID LYGAAKT  SSG S+KG+GMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPV APNW+LNCNKCN LVFLPQGAHRI+TTN+KC ECDS IIEVDFNKKTTPLE GATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRG---GRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGR RGRGRG   GRGR +G+LMDPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRG---GRGRGAGRLMDPKMSFRDF

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L9C7 DNA topoisomerase

0.0e+00

91.32

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HA+YKVTSVIGH+FSIDF   FQ+W +TDPLDLFQASVIKTESNPKAHI QHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYI+Q GYELNLDWERGKLFDCDV  MFQKRV EDGI EVTEISEKQE+K RPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLH+L+KNPEWGDYVR+LLSDGYSKPRSGTD GDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  V  KGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIE QITLVAKGQ DH SVVQ+ LQQF+QKYSYFVKKIDHMDALFEAQFSPLADSGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC  CEEVYYLPQKGTIKLYKELTCPLDNFELLI+SLPGPEGKSFPLCPYCYNSPPFEGI+ LYGA+K   SSG S+KG+GMPCF+CPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPVSAPNW+LNCNKCN LVFLP+GAHRISTT DKC +CDS IIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGS--RGRSRGRGRGGRGRGAGRLMDPKMSFRDF
        GKSF R RGS  RGR RGRGRGGRGR +G+ MDPKMSFRDF
Subjt:  GKSFFRGRGS--RGRSRGRGRGGRGRGAGRLMDPKMSFRDF

A0A1S3AYH7 DNA topoisomerase

0.0e+00

91.58

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HA+YKVTSVIGHIFSIDF   FQ+W TT+PLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDV  MFQKRV EDGI EVTEISEKQE+K RPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLH+L+KNPEWGDYVR+LLSDGYSKPRSGTD GDHPPITPMC ATEDMLGRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  V  KGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIE QITLVAKGQ DH SVV++ LQQFKQKYSYFVKKID MDALFEAQFSPLADSGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC  CEEVYYLPQKGTIKLYKELTCPLDNFELLI SLPGPEGKSFPLCPYCYNSPPFEGID LYGA+KT  SSG S+KG+GMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPVSAPNW+LNCNKCN LVFLPQGAHRISTT+DKC +CDS IIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGS----RGRSRGRGRGGRGRGAGRLMDPKMSFRDF
        G SF R R S    RGR RGRGRGGRGR +G+ MDPKMSFRDF
Subjt:  GKSFFRGRGS----RGRSRGRGRGGRGRGAGRLMDPKMSFRDF

A0A6J1CBL5 DNA topoisomerase

0.0e+00

99.41

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPP+TPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQR+YCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRS--RGRGRGGRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGRS  RGRGRGGRGRGAGR MDPKMSFRDF
Subjt:  GKSFFRGRGSRGRS--RGRGRGGRGRGAGRLMDPKMSFRDF

A0A6J1GWS0 DNA topoisomerase

0.0e+00

92.74

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HAHYKVTSVIGH+FSIDFP RFQ+W  TDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGNE+RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDVA MFQKRV EDGI EVT+ISEKQESK RPSGLNTVNLLKVASSALG+GPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSL+KNPEWGDYVRVLLSDGYSKPRSGTD GDHPPITPM LATEDM+GRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  VM KGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIEQQIT VAKGQ DHFSVVQN LQQFKQKYSYFVKKIDHMDALFEAQFSPLA+SGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC TCEEVYYLPQ+G IKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID LYGAAKT  SSG S+KG+GMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPV APNW+LNCNKCN LVFLPQGAHRI+TTN+KC ECDS IIEVDFNKKTTPLE GATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGR RGRGRG GRGR +G+LMDPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF

A0A6J1IRJ0 DNA topoisomerase

0.0e+00

92.62

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTRKGST++HEFDGRFLG HAHYKVTSVIGH+FSIDFP RFQ+W  TDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDVA MFQKRV EDGI EVT+ISEKQESK RPSGLNTVNLLKVASSALG+GPQMAMQLAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDFKGTLHSL+KNPEWGDYVR+LLSDGYSKPRSGTD GDHPPITPM LATEDM+GRDAWRLYQYVCQHFIGSLS DCKY RTKIQ
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        FSIAGEIF+CTG  V+ KGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LGITLIRGYQCIDPDL LPDIRSFIEQQIT VAKGQ DHFSVVQN LQQFKQKYSYFVKKIDHMDALFEAQFSPLA+SGR+ SKCGKCLRYMKF
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        ISSQPQRLYC TCEEVYYLPQ+G IKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKT  SSG S+KG+GMPCFLCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        RHSLITQGVCACPECSGTLVLDPV APNW+LNCNKCN LVFLPQGAHRI+TTN+KC ECDS IIEVDFNKKTTPLE GATLFVGCILCDEFLHSLLEMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF
        GKSFFRGRGSRGR RGRGRG GRGR +G+LMDPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRG-GRGRGAGRLMDPKMSFRDF

SwissProt top hits

e value

%identity

Alignment

F4ISQ7 DNA topoisomerase 3-beta

0.0e+00

75.33

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTR+GST++HEFDG F G  AHY+VTSVIGH+FS+DFP+++QNW T DP DLF A +IK ESNPKAHI +HLS EARGC  +VLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIE TGF   + ++KVYRARFSSVTEKDI KA+DNLV+PNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R+ISYGPCQTPTLGFCVQR++ 
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        I TFKPEKFW++ PYI ++GYEL L+WER +LFD + A +FQK V E    +V ++SEKQE K RP+GLNTVNLLKVASSALGFGPQ AM LAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDF  TL + + NP WG YV+ LLSDG+  P+SGTDAGDHPPITPM  ATE M+G DAWRLYQYVCQHF+G++SP+CKY RTK++
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
         SI GE FHCTG  V  KGFT+IMPW AV+EKKLP FLKGE+IEV RV+LY+GNT PPDYL+ESELISLMEKHGIGTDASI VHINNIGERNYVQVQ+GR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        ++VPTALGITLIRGYQCIDPDL LPDIRSFIEQQITLVAKGQ DH  VVQ+ +QQF++K+SYFV++I+HMDALFEAQFSPLADSGR+ SKCGKCLRYMK 
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        I++ P RL+C TCEEVYYLPQKGT+KLYKELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGID L+GA+KT  +  K+  G GMPC LCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        +HS+  QGVCACPEC GTLVLDPVS P W+LNCN C+ +V LP+GAHRI+TT+++C ECDS IIE+DFNKKTTPLE+GATL  GC+LCDE L SL+E+KH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRGGRGRGAGRLMDPKMSFRDF
        G+SF R RG RGR RGRGRG  GR   + +DPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRGGRGRGAGRLMDPKMSFRDF

O95985 DNA topoisomerase 3-beta-1

2.5e-254

51.38

Show/hide

Query:  GSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLF-QASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECT
        G+  +HE+ G F G    +K+TSV GH+ ++DF  ++  W   DP +LF QA   K E+NPK ++ + L  E RGCD +VLWLDCD+EGENICFEV++  
Subjt:  GSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLF-QASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECT

Query:  ------GFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHL
                GG    K V+RARFSS+T+ DI  A+  L +P+ NEAL+VDARQE+DL++G AFTRFQT +FQGKYG+LDS LIS+GPCQTPTLGFCV+RH 
Subjt:  ------GFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHL

Query:  QITTFKPEKFWSVCPYI-MQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYT
        +I +FKPE +W +   +       L LDW+R ++FD ++A MF      +   +V   S K+++K RP  LNTV +L+VASS+LG GPQ AMQ AERLYT
Subjt:  QITTFKPEKFWSVCPYI-MQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYT

Query:  QGFISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTK
        QG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G DAGDHPPITPM  ATE  LG DAWRLY+Y+ +HFI ++S DCKY ++ 
Subjt:  QGFISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTK

Query:  IQFSIAGEIFHCTGVHVMAKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQ
        I F I  E+F C+G  V++ GFT +MPW +V  E+ LP   +G+   V  V + +  T PPDYL+E+ELI+LMEKHGIGTDASIPVHINNI +RNYV V+
Subjt:  IQFSIAGEIFHCTGVHVMAKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQ

Query:  AGRRLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRY
        +GRRL PT LGI L+ GY  ID +L LP IRS +E+Q+ L+A+G+ D+  V+ + L  FK+K+ YFV  I  MD L E  FSPLA +G+  S+CGKC R+
Subjt:  AGRRLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRY

Query:  MKFISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPH
        MK+I ++P RL+C+ C+E Y LPQ GTIKLYKEL CPLD+FEL+++S  G  GKS+PLCPYCYN PPF  +                    GM C  C H
Subjt:  MKFISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPH

Query:  PTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLL
        P+C+HSL   G+  C EC SG LVLDP S P W++ CNKCN +    + AHR+  + D C  C++ +++VDFNK  +PL    T  +GC+ CD     L+
Subjt:  PTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLL

Query:  EMKHGKSFF-RGRGSRGRSRGRGRGGRGRGAGR
        E+KH  S     RG  GR +GRGRG   R  G+
Subjt:  EMKHGKSFF-RGRGSRGRSRGRGRGGRGRGAGR

O96651 DNA topoisomerase 3-beta

2.2e-234

48.54

Show/hide

Query:  HEFDGRFLGL-HAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFG-G
        HE+ G F      H+++TSV GH+ S+DF  ++  W   DP+ LF  +  K E+NPK ++R+ L+ EARGCD LVLWLDCD+EGENICFEV++       
Subjt:  HEFDGRFLGL-HAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFG-G

Query:  NEFRKKV-YRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEK
        N +  +V YRA FS++TEKDI KA++ L  PN NEA +VDARQE+DL++G AFTRFQT FFQ +YG+LDS LISYGPCQTPTLGFCV+RH  I TFKPE 
Subjt:  NEFRKKV-YRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEK

Query:  FWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTE
        FW +   ++    E+ L+W RG++F  D+A+M   RV E     V  ++ K+  K +P  LNTV L+++ SS LG GP  AMQ+AERLYTQG+ISYPRTE
Subjt:  FWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTE

Query:  STAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQFSIAGEIF
        +  YP++FD    LH L  + ++G+  R +L D    PR G DAGDHPPITPM L       RD WR+Y+++C+HF+G++S D KY  T  + S+  E F
Subjt:  STAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQFSIAGEIF

Query:  HCTGVHVMAKGFTSIMPWLAV-NEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTAL
         CT   ++  GFT +M W A   ++  P F++G ++ +  V L +  T PPDYL+ESELI+LME+HGIGTDASIPVHINNI +RNYV ++ GR+L+PT L
Subjt:  HCTGVHVMAKGFTSIMPWLAV-NEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTAL

Query:  GITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKFISSQPQR
        GI L+ GYQ IDP+L LP +R+ +E+ +TL+A+G  +   V+++A++ FK K+ YFVK ID MDALFE  FSPLA+SG++ S+CGKC RYMK+I ++P R
Subjt:  GITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKFISSQPQR

Query:  LYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTCRHSLITQ
        L+C+ C+E Y LP  G +K+Y+E  CPLD+F+LL FS  G +G+S+P CPYCYN PPF  +  L G                  C  C +  C HSL T 
Subjt:  LYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTCRHSLITQ

Query:  GVCACPEC-SGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH----GK
        G+ +C EC +G LVLD   AP W+L CN+C+ ++   +GA +I+    KC EC ++ + V +    +  +DG+    GCI C      L+E KH     +
Subjt:  GVCACPEC-SGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH----GK

Query:  SFFRGRGSRGRSRGRGRGGRGRGA
            G G RG   GRG GG G  A
Subjt:  SFFRGRGSRGRSRGRGRGGRGRGA

Q0J0S6 DNA topoisomerase 3-beta

0.0e+00

73.43

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        +MSTRKGSTD+HEFDG F G HA +KVTSVIGH+ S+DFP  +QNW  TDP+DLF A V+++E NPKAHIR+HL++EARGC  LVLWLDCDREGENIC+E
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VI+CTG   +E  ++++RA+FSSVTEKDI+ A++NLV P+++EALAVDARQEIDLKVGVAFTRFQT +FQGKYGNLDSR+ISYGPCQTPTLGFCVQR+ Q
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        ITTFKPEKFWS+  Y++++G E+ L+W+R KLFD DV VMFQK V  DGI++VT+IS K+E K RP GLNTVNLLKVASSALG GPQ AM LAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDF+  L +L  NP W + VR LL  G+ KP+ G DAGDHPPITPM LATE+ LG DAWRLYQY+CQHFIG++SPDC+YTRT I+
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
        F+  GE FHC G  V +KGFTSIMPWLAV+E  +P + KG+ + + +VD+Y+G+TTPPDYLSESELISLMEK+GIGTDASIPVH+NNI ERNYVQV +GR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        RLVPT LG TLIRGYQCID DL LPDIR FIEQQITL+AKG+ DH  VVQ+ LQQF +KYSYFVKKI++MDALFEAQFSPLADSGR  SKCGKC RYMK+
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        IS+QP RLYC TCEEVYYLPQ G+IKLYKE+ CPLD FELL+FS+ GP+ KSFPLCP+CYNSPPFEGID L+GA K    +GK  KG GMPCFLC HPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        + S+ITQGVCACPEC+GTL+LDPVSAP WRL CN+CN +V LP  AH+ISTT+ KC  C+S IIEVDFNKKTTPL+DGATL  GCILCDE LHSL+EMKH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFF--RGRGSRGRSRGRGRG-GRG-RGAGRLMDPKMSFRDF
        GKSFF  RGRG RGR RGRGRG  RG RG+ R  DPKMSFRDF
Subjt:  GKSFF--RGRGSRGRSRGRGRG-GRG-RGAGRLMDPKMSFRDF

Q9Z321 DNA topoisomerase 3-beta-1

4.5e-256

51.59

Show/hide

Query:  MSTRK---GSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLF-QASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENI
        MS+ K   G+  +H++ G F G   H+K+TSV GH+ ++DF  ++  W   DP +LF QA   K E+NPK ++ + L  E RGCD +VLWLDCD+EGENI
Subjt:  MSTRK---GSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLF-QASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENI

Query:  CFEVIEC---TGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFC
        CFEV++         +   K V+RARFSS+T+ DI  A+  L +P+ NEAL+VDARQE+DL++G AFTRFQT +FQGKYG+LDS LIS+GPCQTPTLGFC
Subjt:  CFEVIEC---TGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFC

Query:  VQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGKLFDCDVAVMF--QKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQ
        V+RH +I +FKPE +W +   +  +  E L LDW+R ++FD ++A MF    ++ ++  VE T  S K+++K RP  LNTV +L+VASSALG GPQ AMQ
Subjt:  VQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGKLFDCDVAVMF--QKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQ

Query:  LAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPD
        +AERLYTQG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G DAGDHPPITPM  ATE  LG DAWRLY+Y+ +HFI ++S D
Subjt:  LAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPD

Query:  CKYTRTKIQFSIAGEIFHCTGVHVMAKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGE
        CKY ++ I F I  E F C G  V++ GFT IMPW +V  E+ LP   KG+   V  V + +  T+PPDYL+E+ELI+LMEKHGIGTDASIPVHINNI +
Subjt:  CKYTRTKIQFSIAGEIFHCTGVHVMAKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGE

Query:  RNYVQVQAGRRLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSK
        RNYV V++GRRL PT LGI L+ GY  ID +L LP IRS +E+Q+ L+A+G+ D+  V+ + L  FK+K+ YFV  I  MD L E  FSPLA +G+  S+
Subjt:  RNYVQVQAGRRLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSK

Query:  CGKCLRYMKFISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGM
        CGKC R+MK+I ++P RL+C+ C+E Y LPQ GTIKLYKEL CPLD+FEL+++S  G  GKS+PLCPYCYN PPF  +                    GM
Subjt:  CGKCLRYMKFISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGM

Query:  PCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCD
         C  C HPTC+HSL   G+  C EC +G LVLDP S P W++ CN CN +    + AHR+  + D C+ C++ +++VDFNK  +PL    T   GCI CD
Subjt:  PCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCD

Query:  EFLHSLLEMKHGKS---FFRGRGSRGRSRGRGRGGRGRGAGRLMDPK
             L+E+KH  S     RG   R + RGRGRG R  G      PK
Subjt:  EFLHSLLEMKHGKS---FFRGRGSRGRSRGRGRGGRGRGAGRLMDPK

Arabidopsis top hits

e value

%identity

Alignment

AT2G32000.1 DNA topoisomerase, type IA, core

0.0e+00

75.33

Show/hide

Query:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        QMSTR+GST++HEFDG F G  AHY+VTSVIGH+FS+DFP+++QNW T DP DLF A +IK ESNPKAHI +HLS EARGC  +VLWLDCDREGENICFE
Subjt:  QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ
        VIE TGF   + ++KVYRARFSSVTEKDI KA+DNLV+PNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R+ISYGPCQTPTLGFCVQR++ 
Subjt:  VIECTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQ

Query:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG
        I TFKPEKFW++ PYI ++GYEL L+WER +LFD + A +FQK V E    +V ++SEKQE K RP+GLNTVNLLKVASSALGFGPQ AM LAERLYTQG
Subjt:  ITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQG

Query:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ
        FISYPRTESTAYPSSFDF  TL + + NP WG YV+ LLSDG+  P+SGTDAGDHPPITPM  ATE M+G DAWRLYQYVCQHF+G++SP+CKY RTK++
Subjt:  FISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQ

Query:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR
         SI GE FHCTG  V  KGFT+IMPW AV+EKKLP FLKGE+IEV RV+LY+GNT PPDYL+ESELISLMEKHGIGTDASI VHINNIGERNYVQVQ+GR
Subjt:  FSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGR

Query:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF
        ++VPTALGITLIRGYQCIDPDL LPDIRSFIEQQITLVAKGQ DH  VVQ+ +QQF++K+SYFV++I+HMDALFEAQFSPLADSGR+ SKCGKCLRYMK 
Subjt:  RLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKF

Query:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC
        I++ P RL+C TCEEVYYLPQKGT+KLYKELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGID L+GA+KT  +  K+  G GMPC LCPHPTC
Subjt:  ISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTC

Query:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH
        +HS+  QGVCACPEC GTLVLDPVS P W+LNCN C+ +V LP+GAHRI+TT+++C ECDS IIE+DFNKKTTPLE+GATL  GC+LCDE L SL+E+KH
Subjt:  RHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKH

Query:  GKSFFRGRGSRGRSRGRGRGGRGRGAGRLMDPKMSFRDF
        G+SF R RG RGR RGRGRG  GR   + +DPKMSFRDF
Subjt:  GKSFFRGRGSRGRSRGRGRGGRGRGAGRLMDPKMSFRDF

AT2G32000.2 DNA topoisomerase, type IA, core

0.0e+00

74.94

Show/hide

Query:  HIFSI---DFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEFRKKVYRARFSSVTEKDI
        H+ S+   DFP+++QNW T DP DLF A +IK ESNPKAHI +HLS EARGC  +VLWLDCDREGENICFEVIE TGF   + ++KVYRARFSSVTEKDI
Subjt:  HIFSI---DFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEFRKKVYRARFSSVTEKDI

Query:  LKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER
         KA+DNLV+PNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R+ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER
Subjt:  LKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER

Query:  GKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLLKNP
         +LFD + A +FQK V E    +V ++SEKQE K RP+GLNTVNLLKVASSALGFGPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL + + NP
Subjt:  GKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLLKNP

Query:  EWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQFSIAGEIFHCTGVHVMAKGFTSIMPWLAV
         WG YV+ LLSDG+  P+SGTDAGDHPPITPM  ATE M+G DAWRLYQYVCQHF+G++SP+CKY RTK++ SI GE FHCTG  V  KGFT+IMPW AV
Subjt:  EWGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQFSIAGEIFHCTGVHVMAKGFTSIMPWLAV

Query:  NEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTALGITLIRGYQCIDPDLGLPDIRS
        +EKKLP FLKGE+IEV RV+LY+GNT PPDYL+ESELISLMEKHGIGTDASI VHINNIGERNYVQVQ+GR++VPTALGITLIRGYQCIDPDL LPDIRS
Subjt:  NEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTALGITLIRGYQCIDPDLGLPDIRS

Query:  FIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKFISSQPQRLYCNTCEEVYYLPQKGTIKLYK
        FIEQQITLVAKGQ DH  VVQ+ +QQF++K+SYFV++I+HMDALFEAQFSPLADSGR+ SKCGKCLRYMK I++ P RL+C TCEEVYYLPQKGT+KLYK
Subjt:  FIEQQITLVAKGQVDHFSVVQNALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKFISSQPQRLYCNTCEEVYYLPQKGTIKLYK

Query:  ELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNW
        ELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGID L+GA+KT  +  K+  G GMPC LCPHPTC+HS+  QGVCACPEC GTLVLDPVS P W
Subjt:  ELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNW

Query:  RLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRSRGRGRGGRGRGAGRL
        +LNCN C+ +V LP+GAHRI+TT+++C ECDS IIE+DFNKKTTPLE+GATL  GC+LCDE L SL+E+KHG+SF R RG RGR RGRGRG  GR   + 
Subjt:  RLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRSRGRGRGGRGRGAGRL

Query:  MDPKMSFRDF
        +DPKMSFRDF
Subjt:  MDPKMSFRDF

AT5G63920.1 topoisomerase 3alpha

3.9e-106

37.54

Show/hide

Query:  TRKGST---DIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE
        TR+G +    I EFD    G      +TSVIGH+  ++F DR++ W + DP DL+QA V+K     K  I++ L  EAR  D LVLWLDCDREGENI FE
Subjt:  TRKGST---DIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFE

Query:  VIE-CTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKY-----GNLDSRLISYGPCQTPTLGFC
        V++ C     N F   + RA FS++ ++DI +A+ NL  PN+  A AVDARQEIDL++G +FTRFQT   + ++     G   SR+ISYGPCQ PTLGF 
Subjt:  VIE-CTGFGGNEFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKY-----GNLDSRLISYGPCQTPTLGFC

Query:  VQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQES-KHRPSGLNTVNLLKVASSALGFGPQMAMQL
        V+R+ +I   +PE+FW++ C +  + G     +W RG LFD   AV+  +   E+    V  +   +E  K+ P  LNT+ L K AS       +  M++
Subjt:  VQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQES-KHRPSGLNTVNLLKVASSALGFGPQMAMQL

Query:  AERLYTQGFISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSD----GYSKPRSGTDAGDHPPITPMCLAT-EDMLGRDAWRLYQYVCQHFIGS
        AE LY  GFISYPRTE+ ++ S  D +  +    ++P WG Y + LL        +    G D   HPPI P   ++ E    RD   +Y+ V +H++  
Subjt:  AERLYTQGFISYPRTESTAYPSSFDFKGTLHSLLKNPEWGDYVRVLLSD----GYSKPRSGTDAGDHPPITPMCLAT-EDMLGRDAWRLYQYVCQHFIGS

Query:  LSPDCKYTRTKIQFSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINN
        +S       T ++  IAGE F  +G  ++AK +  +  + +     +P + KG++     + L    T PP  L E++L+S M+K GIGTDA++  HI  
Subjt:  LSPDCKYTRTKIQFSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINN

Query:  IGERNYVQVQAGRRLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFK
        + +R Y    A  R  PT LG  L+ GY  +  +L  P++R+ +E  +  V+ G+     V++  LQQ K
Subjt:  IGERNYVQVQAGRRLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQNALQQFK

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

CAGATGTCTACGAGAAAGGGTAGCACAGATATACATGAATTTGATGGGAGATTTCTTGGGCTTCATGCACATTATAAAGTGACATCAGTCATAGGACATATTTTCAGTAT
AGATTTCCCAGATAGATTTCAAAATTGGACAACCACTGATCCCTTGGATCTTTTTCAAGCTTCAGTAATTAAGACGGAATCAAATCCAAAGGCTCATATACGTCAACATT
TAAGTCGAGAAGCACGTGGTTGTGATTGTTTGGTCTTATGGTTGGATTGTGATCGTGAAGGTGAAAATATTTGTTTCGAAGTTATTGAGTGCACCGGATTTGGTGGCAAT
GAATTTCGGAAAAAAGTGTATCGTGCAAGGTTTTCTTCTGTTACTGAAAAAGATATTTTGAAGGCTTTGGATAACCTTGTTCAACCTAATAGAAATGAGGCACTGGCTGT
AGATGCTCGACAAGAGATAGATTTGAAAGTAGGAGTTGCCTTTACGCGTTTTCAGACTACCTTCTTTCAGGGTAAATATGGAAACCTTGATTCCAGACTCATCTCCTATG
GGCCATGCCAAACTCCCACACTTGGGTTTTGTGTACAGCGTCATTTGCAAATAACTACTTTTAAGCCAGAAAAATTTTGGTCTGTGTGCCCTTATATTATGCAAAATGGA
TATGAACTTAATCTAGACTGGGAGCGTGGCAAGTTATTCGATTGTGATGTTGCTGTAATGTTTCAAAAGCGGGTAACAGAAGATGGGATTGTAGAAGTAACAGAAATATC
TGAGAAACAAGAAAGCAAACATCGGCCTTCTGGACTAAATACAGTGAACCTTCTGAAGGTTGCTTCAAGCGCACTAGGCTTTGGACCTCAAATGGCAATGCAACTAGCTG
AACGATTGTATACACAAGGATTCATCAGCTATCCACGTACAGAGAGTACAGCTTATCCTTCTTCATTTGACTTCAAAGGCACTCTACACTCCCTTTTGAAAAATCCAGAA
TGGGGTGATTATGTACGGGTGCTTCTATCTGATGGATACAGTAAACCACGATCAGGAACTGATGCAGGTGATCATCCTCCTATTACTCCAATGTGTTTAGCAACTGAAGA
TATGCTAGGGAGAGATGCTTGGAGATTGTACCAGTACGTGTGTCAACACTTCATTGGGTCTCTGTCTCCTGACTGCAAGTATACTAGGACGAAGATACAGTTTTCAATTG
CTGGAGAAATATTCCATTGTACTGGGGTGCATGTTATGGCAAAAGGATTCACCTCCATTATGCCATGGTTGGCAGTAAATGAAAAGAAACTACCTCAGTTTCTGAAGGGA
GAGAAAATAGAAGTTGCAAGGGTGGATCTTTATCAGGGTAACACCACGCCTCCCGATTATTTAAGTGAAAGTGAGTTGATTTCTCTCATGGAGAAGCATGGAATAGGCAC
AGATGCATCAATACCTGTACACATTAACAACATAGGCGAACGCAACTATGTGCAGGTTCAAGCTGGAAGGAGGTTGGTTCCAACTGCCTTAGGTATCACTTTAATCAGAG
GTTATCAATGTATTGACCCAGATCTCGGCCTACCAGATATTCGAAGTTTCATTGAGCAACAGATCACTCTTGTTGCCAAGGGTCAAGTAGATCATTTTAGTGTTGTGCAG
AATGCACTGCAACAGTTCAAGCAAAAGTACAGCTACTTCGTTAAGAAGATTGATCACATGGATGCTCTGTTTGAAGCACAATTTTCTCCTCTTGCTGATTCTGGACGCTC
TTTTAGCAAATGTGGCAAATGCCTGCGGTATATGAAGTTTATTTCTTCCCAACCACAGCGCCTGTACTGTAATACATGTGAGGAGGTTTATTATCTTCCGCAGAAGGGAA
CAATAAAGCTGTATAAGGAACTTACATGTCCTTTGGATAACTTCGAACTTTTGATTTTTTCCTTACCTGGCCCAGAAGGCAAGTCATTTCCTCTTTGCCCATACTGCTAC
AATAGTCCTCCATTTGAGGGTATCGATGCATTATATGGTGCTGCTAAAACCACCCAAAGTTCTGGAAAATCGACCAAGGGAATTGGTATGCCATGCTTCCTCTGCCCACA
CCCAACATGTCGACATTCTTTAATAACCCAAGGAGTCTGTGCTTGCCCGGAATGTAGCGGGACGCTTGTCCTAGATCCAGTGAGTGCACCCAACTGGAGACTCAACTGCA
ACAAGTGCAATTTCCTTGTCTTCCTTCCTCAGGGTGCTCATAGGATCTCTACCACTAACGACAAGTGTGACGAATGCGACTCGAAAATTATAGAAGTCGACTTCAACAAG
AAAACTACACCATTGGAGGACGGAGCTACACTGTTTGTTGGCTGCATTCTTTGTGATGAGTTTCTCCATTCACTTTTGGAGATGAAGCATGGAAAATCATTCTTCAGAGG
CAGAGGTTCCAGAGGAAGAAGTAGAGGAAGGGGAAGGGGAGGAAGAGGACGCGGTGCAGGGAGATTGATGGACCCAAAAATGAGTTTCCGAGATTTC

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

QMSTRKGSTDIHEFDGRFLGLHAHYKVTSVIGHIFSIDFPDRFQNWTTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGN
EFRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNG
YELNLDWERGKLFDCDVAVMFQKRVTEDGIVEVTEISEKQESKHRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLLKNPE
WGDYVRVLLSDGYSKPRSGTDAGDHPPITPMCLATEDMLGRDAWRLYQYVCQHFIGSLSPDCKYTRTKIQFSIAGEIFHCTGVHVMAKGFTSIMPWLAVNEKKLPQFLKG
EKIEVARVDLYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTALGITLIRGYQCIDPDLGLPDIRSFIEQQITLVAKGQVDHFSVVQ
NALQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRSFSKCGKCLRYMKFISSQPQRLYCNTCEEVYYLPQKGTIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCY
NSPPFEGIDALYGAAKTTQSSGKSTKGIGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWRLNCNKCNFLVFLPQGAHRISTTNDKCDECDSKIIEVDFNK
KTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRSRGRGRGGRGRGAGRLMDPKMSFRDF

MS014349 (gene) of Bitter gourd (TR) v1 genome