CuGenDBv2

Gene ID	MS015447
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	Fanconi-associated nuclease
Genome location	scaffold424:84583..85092
RNA-Seq Expression	MS015447
Synteny	MS015447
Gene Ontology terms	GO:0007129 - synapsis (biological process) GO:0036297 - interstrand cross-link repair (biological process) GO:0090305 - nucleic acid phosphodiester bond hydrolysis (biological process) GO:0005634 - nucleus (cellular component) GO:0003677 - DNA binding (molecular function) GO:0004528 - phosphodiesterase I activity (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (molecular function)
InterPro domains	IPR033315 - Fanconi-associated nuclease 1-like

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022155222.1 fanconi-associated nuclease 1 homolog isoform X1 [Momordica charantia]

9.5e-86

100

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

XP_022949023.1 fanconi-associated nuclease 1 homolog [Cucurbita moschata]

5.5e-57

75.9

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRGTKRKLTQS+LLQLNF  R KV+H S VLK EKNESS  PDD  ++ +VHRLP +AS+NE +DKI C SL EC  Q QRDCLLD+ +NSERTNG
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIV-TDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        ATEI SP NKG TS +V T+KDDLSG+ILET+IVGRKFSDEKELNLGA+ISLERDPTNVKDPNAIK
Subjt:  ATEICSPKNKGITSEIV-TDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

XP_038889849.1 fanconi-associated nuclease 1 homolog isoform X1 [Benincasa hispida]

2.4e-57

74.55

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRG KRKLTQSTLLQLNF  RSKV+HQS VLK EKNESS  P D LM   VH+LP +ASH E +D+I+CE LVEC  + Q+DCLLDT +N ERTN 
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        A+EICSPKNK ITS +VT KDDLSG+IL+T+IVGRKFSDEKELNLG +ISLERDPTNV DPNAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

XP_038889850.1 fanconi-associated nuclease 1 homolog isoform X2 [Benincasa hispida]

2.4e-57

74.55

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRG KRKLTQSTLLQLNF  RSKV+HQS VLK EKNESS  P D LM   VH+LP +ASH E +D+I+CE LVEC  + Q+DCLLDT +N ERTN 
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        A+EICSPKNK ITS +VT KDDLSG+IL+T+IVGRKFSDEKELNLG +ISLERDPTNV DPNAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

XP_038889851.1 fanconi-associated nuclease 1 homolog isoform X3 [Benincasa hispida]

2.4e-57

74.55

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRG KRKLTQSTLLQLNF  RSKV+HQS VLK EKNESS  P D LM   VH+LP +ASH E +D+I+CE LVEC  + Q+DCLLDT +N ERTN 
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        A+EICSPKNK ITS +VT KDDLSG+IL+T+IVGRKFSDEKELNLG +ISLERDPTNV DPNAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

TrEMBL top hits

e value

%identity

Alignment

A0A1S4E2H4 Fanconi-associated nuclease

1.4e-50

69.88

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        D CLSRGTKRKLTQSTLLQLNF  RSK + QS VLK EK ESS  P D LM S VH+LP +AS  E +D+I+CESLVEC  + Q+DCL D  ++ ERTNG
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEI-CSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        A+EI CSPKNK  TS ++  +DDLSG+IL+T+IVGRKFSDEKELNLG  ISLERDPTNVKDPNAIK
Subjt:  ATEI-CSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

A0A5D3BMW6 Fanconi-associated nuclease

1.4e-50

69.88

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        D CLSRGTKRKLTQSTLLQLNF  RSK + QS VLK EK ESS  P D LM S VH+LP +AS  E +D+I+CESLVEC  + Q+DCL D  ++ ERTNG
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEI-CSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        A+EI CSPKNK  TS ++  +DDLSG+IL+T+IVGRKFSDEKELNLG  ISLERDPTNVKDPNAIK
Subjt:  ATEI-CSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

A0A6J1DNS1 Fanconi-associated nuclease

4.6e-86

100

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

A0A6J1GAX8 Fanconi-associated nuclease

2.6e-57

75.9

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRGTKRKLTQS+LLQLNF  R KV+H S VLK EKNESS  PDD  ++ +VHRLP +AS+NE +DKI C SL EC  Q QRDCLLD+ +NSERTNG
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIV-TDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        ATEI SP NKG TS +V T+KDDLSG+ILET+IVGRKFSDEKELNLGA+ISLERDPTNVKDPNAIK
Subjt:  ATEICSPKNKGITSEIV-TDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

A0A6J1KFS7 Fanconi-associated nuclease

1.0e-56

76.51

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        DACLSRGTKRKLTQS+LLQLNF  R KV+H S VLK EKNESS  PDD  ++ +VHRLP +AS+NE +DKI C SL EC  Q QRDCLLDT  NSERTNG
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIV-TDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
        ATEI SP NKG TS +V T KDDLSG+ILET+IVGRKFSDEKELNLGA ISLERDPTNVKDPNAIK
Subjt:  ATEICSPKNKGITSEIV-TDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

SwissProt top hits

e value

%identity

Alignment

Q5SNL7 Fanconi-associated nuclease 1 homolog

1.9e-12

32.45

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSE----
        D CL+RGTKRKLTQSTLL  +FS ++   +    L         +P D  + S        A  + ++DK+  +            CL  +PD SE    
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSE----

Query:  --------------RTNGATEIC---SPKNKGITSEI--VTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
                        NG  + C    P     +S I  ++  D  + V+++T IVGR+F +  EL  GA+I+L RDP N KDP+AIK
Subjt:  --------------RTNGATEIC---SPKNKGITSEI--VTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

Q5XVJ4 Fanconi-associated nuclease 1 homolog

2.6e-09

33.33

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        D  LS   KR+LTQ+TLLQ +F    K      V+  +  + S    +    S+V R       +E S+ I C+                  D S     
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
            CSP  +     +  D+D  +G  +ET+IVGRKFSD ++L +G +I L R P NVKD NAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

Arabidopsis top hits

e value

%identity

Alignment

AT1G48360.1 zinc ion binding;nucleic acid binding;hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides

1.8e-10

33.33

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        D  LS   KR+LTQ+TLLQ +F    K      V+  +  + S    +    S+V R       +E S+ I C+                  D S     
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
            CSP  +     +  D+D  +G  +ET+IVGRKFSD ++L +G +I L R P NVKD NAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

AT1G48360.2 zinc ion binding;nucleic acid binding;hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides

1.8e-10

33.33

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        D  LS   KR+LTQ+TLLQ +F    K      V+  +  + S    +    S+V R       +E S+ I C+                  D S     
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
            CSP  +     +  D+D  +G  +ET+IVGRKFSD ++L +G +I L R P NVKD NAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

AT1G48360.3 zinc ion binding;nucleic acid binding;hydrolases, acting on acid anhydrides, in phosphorus-containing anhydrides

1.8e-10

33.33

Show/hide

Query:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG
        D  LS   KR+LTQ+TLLQ +F    K      V+  +  + S    +    S+V R       +E S+ I C+                  D S     
Subjt:  DACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNG

Query:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK
            CSP  +     +  D+D  +G  +ET+IVGRKFSD ++L +G +I L R P NVKD NAIK
Subjt:  ATEICSPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ACTTTGTGGTTTCCAGATGCATGCTTATCTAGGGGAACGAAGCGGAAGTTGACACAGAGCACTCTTCTTCAATTAAACTTCTCTCCTCGATCAAAAGTTAAGCATCAATC
TTGTGTTCTGAAATTAGAGAAAAATGAGTCTTCTGCAGATCCTGATGACGATCTAATGGAAAGTGTTGTCCACAGACTGCCTACAAATGCCTCTCATAATGAAAGTAGTG
ACAAAATTCTGTGTGAATCATTAGTAGAATGTGTAGAGCAGCGACAGAGGGACTGTCTATTGGATACCCCAGATAATAGTGAAAGAACTAATGGTGCTACAGAAATTTGT
TCTCCCAAGAATAAAGGAATTACATCTGAGATCGTTACTGACAAGGATGATTTATCTGGGGTGATTCTTGAAACTTATATTGTTGGTCGTAAGTTTAGTGATGAAAAGGA
GTTAAATCTTGGGGCAAACATCTCTCTTGAAAGAGATCCTACCAATGTAAAGGATCCCAATGCCATCAAG

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

TLWFPDACLSRGTKRKLTQSTLLQLNFSPRSKVKHQSCVLKLEKNESSADPDDDLMESVVHRLPTNASHNESSDKILCESLVECVEQRQRDCLLDTPDNSERTNGATEIC
SPKNKGITSEIVTDKDDLSGVILETYIVGRKFSDEKELNLGANISLERDPTNVKDPNAIK

MS015447 (gene) of Bitter gourd (TR) v1 genome