CuGenDBv2

Gene ID	MS015956
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	Aha1_N domain-containing protein
Genome location	scaffold582:126475..130678
RNA-Seq Expression	MS015956
Synteny	MS015956
Gene Ontology terms	GO:0006457 - protein folding (biological process) GO:0032781 - positive regulation of ATPase activity (biological process) GO:0005829 - cytosol (cellular component) GO:0001671 - ATPase activator activity (molecular function) GO:0051087 - chaperone binding (molecular function) GO:0051879 - Hsp90 protein binding (molecular function)
InterPro domains	IPR015310 - Activator of Hsp90 ATPase, N-terminal IPR036338 - Activator of Hsp90 ATPase, Aha1 IPR039981 - Activator of 90kDa heat shock protein ATPase-like

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_011660198.1 uncharacterized protein LOC101207721 [Cucumis sativus]

2.0e-95

91.58

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Query:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK
        MEN GAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELL+SVASLEFSSGKAEIADVSK
Subjt:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK
        CVGDAFLVTVRNKKRVGYTYELTLK+KG EWTIR+EKKTVKG IDVPEFSFGELDDLQM+VRLSEE+DLL EDK ++CQDLKRFLQPVREQLLQFEQELK
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK

Query:  ER
        ER
Subjt:  ER

XP_022157075.1 uncharacterized protein LOC111023885 [Momordica charantia]

3.5e-103

99.5

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        VGDAFLVTVRNKKRVGYTYELTLKVKG EWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

XP_022933923.1 uncharacterized protein LOC111441189 [Cucurbita moschata]

1.7e-94

90.55

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        VGDAFLVTVRNKKRVGYTYELTLK+KG EWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQDLKRFLQPVR +LLQFEQELKE
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

XP_022973883.1 uncharacterized protein LOC111472472 [Cucurbita maxima]

1.7e-94

90.05

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMK+LLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        VGDAFLVTVRNKKRVGYTYELTLK+KG EWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQD KRFLQPVRE+LLQFEQELKE
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

XP_038878257.1 uncharacterized protein LOC120070542 [Benincasa hispida]

1.2e-95

92.08

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Query:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK
        MEN GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELLMSVASLEFS+GKAEIADVSK
Subjt:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK
        CVGDAFLVTVRNKKRVGYTYE TLK+KG EWTIR+EKK VKG IDVPEFSFGELDDLQM+VRLSEEKDLL EDKL++CQDLKRFLQPVRE+LLQFEQELK
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK

Query:  ER
        ER
Subjt:  ER

TrEMBL top hits

e value

%identity

Alignment

A0A0A0M014 Aha1_N domain-containing protein

9.9e-96

91.58

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Query:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK
        MEN GAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELL+SVASLEFSSGKAEIADVSK
Subjt:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK
        CVGDAFLVTVRNKKRVGYTYELTLK+KG EWTIR+EKKTVKG IDVPEFSFGELDDLQM+VRLSEE+DLL EDK ++CQDLKRFLQPVREQLLQFEQELK
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK

Query:  ER
        ER
Subjt:  ER

A0A1S3B8I3 uncharacterized protein LOC103487198

1.9e-94

90.1

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Query:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK
        MEN GAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWA+ RMKELLMSVASLEFSSGKAEIADVSK
Subjt:  MEN-GAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK
        CVGDAFLVTVRNKKRVGYTYELTLK+KG EWT+++EKK VKG IDVPEFSFGELDDLQM+VRLSEEKDLL EDK ++CQDLKRFLQPVRE+LLQFEQELK
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELK

Query:  ER
        ER
Subjt:  ER

A0A6J1DS44 uncharacterized protein LOC111023885

1.7e-103

99.5

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Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        VGDAFLVTVRNKKRVGYTYELTLKVKG EWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

A0A6J1F676 uncharacterized protein LOC111441189

8.4e-95

90.55

Show/hide

Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMKELLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        VGDAFLVTVRNKKRVGYTYELTLK+KG EWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQDLKRFLQPVR +LLQFEQELKE
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

A0A6J1IEG5 uncharacterized protein LOC111472472

8.4e-95

90.05

Show/hide

Query:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC
        MENGAVSSETQQGASYTYWVRE R+DAAPLPVPRKLSA+DI+ASQASQPPTLGSVWNRAGTWEEKNLNKWAS RMK+LLMSV SLEFSSGKAEI DVSKC
Subjt:  MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE
        VGDAFLVTVRNKKRVGYTYELTLK+KG EWTI++EKKTVKG IDVPEFSFGELDDLQMEVRLSEEKDLL  DK ++CQD KRFLQPVRE+LLQFEQELKE
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKE

Query:  R
        R
Subjt:  R

SwissProt top hits

e value

%identity

Alignment

Q8BK64 Activator of 90 kDa heat shock protein ATPase homolog 1

5.0e-04

25.2

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Query:  WEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKVKGSEWT-IREEKKTVKGDIDVPEFS-FGELDDLQM
        W E++ + W++ ++K L ++V  +E   GK E+ +V+K  G+A   ++ N+K ++ + YE T+K+    WT   +     KG +++P  S    +D++++
Subjt:  WEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKVKGSEWT-IREEKKTVKGDIDVPEFS-FGELDDLQM

Query:  EVRLSEEKD------LLAEDKLRVCQD
         V L++++       L+ ED +++ ++
Subjt:  EVRLSEEKD------LLAEDKLRVCQD

Arabidopsis top hits

e value

%identity

Alignment

AT5G58110.1 chaperone binding;ATPase activators

4.0e-65

64.25

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Query:  ETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVT
        +T++G+SY YWVREA  DAAP P+P+KLS  D+  + A  P +LGS+WNRAGTWEEK+L KWA+ R+KELL SV SL+FSSGKAEI DV++CVGDAFLVT
Subjt:  ETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVT

Query:  VRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER
        VRNKKRVGYTYEL+LKV+G EW+  E  K VKG +++PEFSFGELDDL+++V+LSE+K+L  + K R+  D+K+FL+P+R +L  FEQELK+R
Subjt:  VRNKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

Sequences

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CDS sequence

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ATGGAGAATGGAGCAGTTTCGTCGGAGACCCAACAGGGGGCGTCCTACACCTATTGGGTCAGGGAAGCGCGGAAGGACGCCGCCCCACTTCCTGTCCCTCGCAAGCTCTC
CGCTGAGGACATTGTCGCTTCTCAAGCGTCTCAGCCTCCTACCCTTGGCTCCGTCTGGAATCGGGCTGGAACATGGGAGGAGAAGAACTTGAATAAATGGGCGAGTGGTA
GAATGAAGGAGTTGCTAATGTCAGTGGCTTCCTTGGAGTTCTCCAGCGGTAAAGCAGAGATAGCGGATGTATCAAAATGTGTTGGAGATGCTTTTTTAGTGACTGTACGT
AACAAGAAACGTGTTGGTTATACATATGAACTTACATTGAAAGTTAAAGGTAGTGAGTGGACTATTAGAGAGGAGAAGAAGACGGTGAAGGGGGATATAGATGTCCCAGA
ATTTTCATTTGGTGAGCTAGATGACTTGCAGATGGAAGTGAGATTGAGCGAAGAGAAGGATCTTCTGGCTGAGGATAAGTTGCGGGTTTGCCAAGATTTGAAGCGGTTTT
TGCAGCCTGTTCGCGAACAGTTGCTTCAATTCGAACAGGAACTCAAAGAAAGA

mRNA sequence

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Protein sequence

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MENGAVSSETQQGASYTYWVREARKDAAPLPVPRKLSAEDIVASQASQPPTLGSVWNRAGTWEEKNLNKWASGRMKELLMSVASLEFSSGKAEIADVSKCVGDAFLVTVR
NKKRVGYTYELTLKVKGSEWTIREEKKTVKGDIDVPEFSFGELDDLQMEVRLSEEKDLLAEDKLRVCQDLKRFLQPVREQLLQFEQELKER

MS015956 (gene) of Bitter gourd (TR) v1 genome