CuGenDBv2

Gene ID	MS016089
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	DNA topoisomerase 2
Genome location	scaffold9_2:308541..315358
RNA-Seq Expression	MS016089
Synteny	MS016089
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0e+00

90.99

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVDS PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+R+L+GE M+PMDPWY+GFSGTIEKTATKEGG SYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRITELPVRRWTNDYK+FLDSVTRV+TKN  DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLE++EKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK
        TDEAEESPE  KGERVSDY YLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KPK
Subjt:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK

Query:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET
        ISRN APKAPRNSKKT NSETI ESMD TTSSSTT EVA+N VVKPKGKAAPRKAPAKK       D+DDDDEVLELKDRLAAYK++SSP+ SEVSAMET
Subjt:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET

Query:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI
        EVP+V AAAKKKEPSKRA AKKKTTAKSAQIS  DDSDD DFEIKE+APPAAKKGGGRK AANAKTTK     KK+E  A +LGQKLITQML PT+NSGI
Subjt:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI

Query:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE
        SPEKKVRK+R SPFNKKSGS+LGR   EEEEE EE GNEGK+MGSASSET +E    +P ARGRSQR NRTQV+YV+SDSDS+PVYE    D DFD+E
Subjt:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE

XP_022152631.1 DNA topoisomerase 2 isoform X1 [Momordica charantia]

0.0e+00

99.6

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSG IEKTATKEGGVSYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
        +NGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD

Query:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
        EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
Subjt:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR

Query:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ
        NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASN VVKPKGKAAPRKAPAKKGKVVNHND DDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ
Subjt:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ

Query:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK
        VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQN+GISPEKK
Subjt:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK

Query:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
        VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
Subjt:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED

XP_022152632.1 DNA topoisomerase 2 isoform X2 [Momordica charantia]

0.0e+00

99.46

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSG IEKTATKEGGVSYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
        +NGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD

Query:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
        EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
Subjt:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR

Query:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ
        NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASN VVKPKGKAAPRKAPAKKGKVVNHND DDDDEVLELKDRLAAYKIDSSPDRSE  AMETEVPQ
Subjt:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ

Query:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK
        VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQN+GISPEKK
Subjt:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK

Query:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
        VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
Subjt:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED

XP_022935015.1 DNA topoisomerase 2 isoform X1 [Cucurbita moschata]

0.0e+00

90.99

Show/hide

Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVDS PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+R+L+GE M+PMDPWY+GFSGTIEKTATKEGG SYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRITELPVRRWTNDYK+FLDSVTRV+TKN  DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLE++EKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK
        TDEAEESPE  KGERVSDY YLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KPK
Subjt:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK

Query:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET
        ISRN APKAPRNSKKT NSETI ESMD TTSSSTT EVA+N VVKPKGKAAPRKAPAKK       D+DDDDEVLELKDRLAAYK++SSP+ SEVSAMET
Subjt:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET

Query:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI
        EVP+V AAAKKKEPSKRA AKKKTTAKSAQIS  DDSDD DFEIKE+APPAAKKGGGRK AANAKTTK     KK+E  A +LGQKLITQML PT+NSGI
Subjt:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI

Query:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE
        SPEKKVRK+R SPFNKKSGS+LGR   EEEEE EE GNEGK+MGSASSET +E    +P ARGRSQR NRTQV+YV+SDSDS+PVYE    D DFD+E
Subjt:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE

XP_022935016.1 DNA topoisomerase 2 isoform X2 [Cucurbita moschata]

0.0e+00

91.12

Show/hide

Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVDS PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+R+L+GE M+PMDPWY+GFSGTIEKTATKEGG SYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRITELPVRRWTNDYK+FLDSVTRV+TKN  DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLE++EKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK
        TDEAEESPE  KGERVSDY YLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KPK
Subjt:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK

Query:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET
        ISRN APKAPRNSKKT NSETI ESMD TTSSSTT EVA+N VVKPKGKAAPRKAPAKKGK     D+DDDDEVLELKDRLAAYK++SSP+ SEVSAMET
Subjt:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET

Query:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI
        EVP+V AAAKKKEPSKRA AKKKTTAKSAQIS  DDSDD DFEIKE+APPAAKKGGGRK AANAKTTK     KK+E  A +LGQKLITQML PT+NSGI
Subjt:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI

Query:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE
        SPEKKVRK+R SPFNKKSGS+LGR   EEEEE EE GNEGK+MGSASSET +E    +P ARGRSQR NRTQV+YV+SDSDS+PVYE    D DFD+E
Subjt:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE

TrEMBL top hits

e value

%identity

Alignment

A0A6J1DGT3 DNA topoisomerase 2

0.0e+00

99.46

Show/hide

Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSG IEKTATKEGGVSYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
        +NGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD

Query:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
        EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
Subjt:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR

Query:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ
        NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASN VVKPKGKAAPRKAPAKKGKVVNHND DDDDEVLELKDRLAAYKIDSSPDRSE  AMETEVPQ
Subjt:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ

Query:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK
        VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQN+GISPEKK
Subjt:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK

Query:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
        VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
Subjt:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED

A0A6J1DIB5 DNA topoisomerase 2

0.0e+00

99.6

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSG IEKTATKEGGVSYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
        +NGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD

Query:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
        EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR
Subjt:  EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISR

Query:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ
        NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASN VVKPKGKAAPRKAPAKKGKVVNHND DDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ
Subjt:  NAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQ

Query:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK
        VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQN+GISPEKK
Subjt:  VGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKK

Query:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
        VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED
Subjt:  VRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

91.12

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVDS PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+R+L+GE M+PMDPWY+GFSGTIEKTATKEGG SYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRITELPVRRWTNDYK+FLDSVTRV+TKN  DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLE++EKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK
        TDEAEESPE  KGERVSDY YLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KPK
Subjt:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK

Query:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET
        ISRN APKAPRNSKKT NSETI ESMD TTSSSTT EVA+N VVKPKGKAAPRKAPAKKGK     D+DDDDEVLELKDRLAAYK++SSP+ SEVSAMET
Subjt:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET

Query:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI
        EVP+V AAAKKKEPSKRA AKKKTTAKSAQIS  DDSDD DFEIKE+APPAAKKGGGRK AANAKTTK     KK+E  A +LGQKLITQML PT+NSGI
Subjt:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI

Query:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE
        SPEKKVRK+R SPFNKKSGS+LGR   EEEEE EE GNEGK+MGSASSET +E    +P ARGRSQR NRTQV+YV+SDSDS+PVYE    D DFD+E
Subjt:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

90.99

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVDS PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        S+KVVID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+R+L+GE M+PMDPWY+GFSGTIEKTATKEGG SYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRITELPVRRWTNDYK+FLDSVTRV+TKN  DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLE++EKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK
        TDEAEESPE  KGERVSDY YLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KPK
Subjt:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK

Query:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET
        ISRN APKAPRNSKKT NSETI ESMD TTSSSTT EVA+N VVKPKGKAAPRKAPAKK       D+DDDDEVLELKDRLAAYK++SSP+ SEVSAMET
Subjt:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET

Query:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI
        EVP+V AAAKKKEPSKRA AKKKTTAKSAQIS  DDSDD DFEIKE+APPAAKKGGGRK AANAKTTK     KK+E  A +LGQKLITQML PT+NSGI
Subjt:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI

Query:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE
        SPEKKVRK+R SPFNKKSGS+LGR   EEEEE EE GNEGK+MGSASSET +E    +P ARGRSQR NRTQV+YV+SDSDS+PVYE    D DFD+E
Subjt:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDE

A0A6J1J555 DNA topoisomerase 2

0.0e+00

90.87

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVE KRPLQNS  ANVDS PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        S+KVVID EQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVF DNMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVV
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNV

Query:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRS

Query:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS
        RFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDII NV+R+LDGE M+PMDPWY+GFSGTIEKTATKEGG SYTVS
Subjt:  RFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVS

Query:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRITELPVRRWTNDYK+FLDSVTRV+TKN  DKEKAAKDPFIEQADHHSDDKTVSI+VHLTEENMILA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKN--DKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLE++EKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNE

Query:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK
        TDEAEESPE  KGERVSDY YLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KPK
Subjt:  TDEAEESPE-AKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPK

Query:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET
        ISRN APKAPRNSKKT NSETI ESMD  TSSSTT EVA+N VVKPKGKAAPRKAPAKKGK     D+D DDEVLELKDRLAAYK++SSP+ SEVSAMET
Subjt:  ISRNAAPKAPRNSKKTINSETIAESMD-TTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMET

Query:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI
        EVP+V AAAKKKEPSKRA AKKKTTAKSAQIS  DDSDD DFEIKE+APPAAKKGGGRK AANAKTTK     KK+E  A +LGQKLITQML PT+NSGI
Subjt:  EVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRK-AANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGI

Query:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFD-DED
        SPEKKVRK+R SPFNKKSGS+LGR   EEEEE EE GNEGK+MGSASSET +E    +P ARGRSQR NRTQV+YV+SDSDS+PVYE  D D++ D DED
Subjt:  SPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLP-ARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFD-DED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

63.59

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Query:  KKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ S  AN+      P KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHR+V+YVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  VIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVIT
         ID E N +SV+NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADG+R KKYKQVF +NMG K EPVIT
Subjt:  VIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVIT

Query:  KCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSE
        KCK  +NWTKVTFKPDL KF M +LE+DVVALMKKRVLDMAGC GKTVKVELNG  +  KSF+DY DL+LK A   +  P  R H K  +RWEI ++LS+
Subjt:  KCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSE

Query:  GQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNVASKS
        GQFQQVSFVNSIATIKGGTHVDYITNQI  Y+MN VNKK K+ANVKAH VK++LWVF+N+LIDNPAFDSQTKETLT RQ+SFGS C++    LK+V  KS
Subjt:  GQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNVASKS

Query:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE
        GI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGGRNSEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQI +N+E
Subjt:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE

Query:  IQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNAS
        IQ IK+ILGLQQ KEY NVK LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+
Subjt:  IQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNAS

Query:  GWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSV
         W IKYYKGLGTST +EGREYF  LG+H+KDF+W D+ DG AIELAFSKKK E RK W+R+FEPGT  D   KLI Y DFVNKELILFS AD        
Subjt:  GWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSV

Query:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF
                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF
Subjt:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF

Query:  PRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVSGIIE
           DD+LL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPR+II NV+RLL+GE ++PMDPWYKGF GTIEK+A KEGG  Y V+G + 
Subjt:  PRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVSGIIE

Query:  EVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFDANGV
        E+ + T RITELP+R+WT DYK+FL+S+T      D     KDP IE    + DD  V I++ +  E +   LQEGL KKFKLT+T+STSNMHLFDA G 
Subjt:  EVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFDANGV

Query:  IKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEE
         KK+DTPEQILEEFFPLRL+YYEK K  +L NL R LL L+NKVRFIL VVNGEI+VSNR++ +L  EL+ KGFTP P+K KS +P+VAGA+++  E +E
Subjt:  IKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEE

Query:  --SPEAKGERVS-------DYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVK
           PE   + VS       DY  LL+L IGTLT+E VQ+L +++ + + E E L      SLWLKDLD  EK+LDE+D   A+ +  R  Q  K  N   
Subjt:  --SPEAKGERVS-------DYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVK

Query:  PKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV-------VVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDR
         K ++   P+  +N+KK       A+S++  + +++ME+ + V       V KPKG+AAP+K          +  ++ +D++  L++RLAAY I+SS ++
Subjt:  PKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV-------VVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDR

Query:  SEVSAMETEVPQVGAAAKKKEPSKRAPAKKKTTA------KSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAA-NAK------TTKPPAAAKKREAAA
        S+  AME+E  Q  AA KK+  +KR  AKKK++          +++D DD DDD  E+++ A P  KKGG + AA NAK        K PAA KKR    
Subjt:  SEVSAMETEVPQVGAAAKKKEPSKRAPAKKKTTA------KSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAA-NAK------TTKPPAAAKKREAAA

Query:  GK-LGQKLITQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDS
         +  GQKL+T ML P + +G SPEKKVRKMR SPFNKKSGSILGR    ++     + + G    +  SE         PAR R QRANRTQ+KY +S+S
Subjt:  GK-LGQKLITQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDS

Query:  DSDPVYEGDDKDDDFDDED
        +S+   + D +  DF+++D
Subjt:  DSDPVYEGDDKDDDFDDED

O46374 DNA topoisomerase 2-alpha

0.0e+00

47.14

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Query:  MAVEKKRPLQNSTVANVDSAPAGPKK--TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDP
        M V   +P+  +   N        KK  +IE +YQKKTQLEHILLRPDTY+GS+E  TQ +WVY+ D  + +R VT+VPGLYKIFDEILVNAADNKQRDP
Subjt:  MAVEKKRPLQNSTVANVDSAPAGPKK--TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDP

Query:  SMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGK
         M  ++V ID E N IS++NNG G+PV  H+ EK+YVP LIFG LLTSSNYDD  KK TGGRNGYGAKL NIFST+F +ETA  + +K +KQ + DNMG+
Subjt:  SMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGK

Query:  KSEPVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWE
          E  + K   G+++T +TF PDL+KF M  L+ D+VALM +R  D+AG   K VKV LNG ++PVK F+ YVDLYLK        P K  H + N RWE
Subjt:  KSEPVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWE

Query:  IVVTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEF
        + +T+SE  FQQ+SFVNSIAT KGG HVDY+ +QI   +++VV KKNK    VKAH VK+++W+F+NALI+NP FDSQTKE +T++  SFGS C+L+ +F
Subjt:  IVVTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEF

Query:  LKNVASKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS
        +K  A   GI++S+L+WV FK    L KK    K  +I GI KL+DAN AGGRNS +CTLILTEGDSAK LA++GLGVVGRD YGVFPLRGK+LNVREAS
Subjt:  LKNVASKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS

Query:  SKQITENKEIQYIKQILGLQQGKEY---NNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEY
         KQI EN EI  I +I+GLQ  K Y   +++K LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLLR   FL EFITPIVK + +N   ++FY++PE+
Subjt:  SKQITENKEIQYIKQILGLQQGKEY---NNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEY

Query:  ESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFE-----------PGTHL-DQTEKLIK
        E WK S   N   W +KYYKGLGTSTSKE +EYF  + +H+  F +    D  AI LAFSKK+I++RK WL HF            P  +L  QT   + 
Subjt:  ESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFE-----------PGTHL-DQTEKLIK

Query:  YSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN
        Y+DF+NKELILFS +D +RSIPS+VDGLKPGQRK+LF  FKRN  +E KV+Q +G V+E S+YHHGE SL  TII +AQ+FVGSNN+NLL P GQFGTR 
Subjt:  YSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN

Query:  HGGKDHASSRYIYTKLSNVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKG
        HGGKD AS RYI+T LS + R LFP  DD  L +L +D Q +EP WY+PIIP VL+NG+EGIGTGWS  +PN++ R+++ N++ L+DGE  +PM P YK 
Subjt:  HGGKDHASSRYIYTKLSNVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKG

Query:  FSGTIEKTATKEGGVSYTVSGIIEEVSDTTLRITELPVRRWTNDYKE-FLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQE
        F GTIE+ A  +    Y +SG +  ++ TT+ I+ELP+R WT  YKE  L+ +      N  EK    P I     +  D TV   V +TEE +  A + 
Subjt:  FSGTIEKTATKEGGVSYTVSGIIEEVSDTTLRITELPVRRWTNDYKE-FLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQE

Query:  GLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFT
        GL K FKL T+++ ++M LFD  G +KKYDT   IL +FF LRL+YY  RK  LL  L  E  +L N+ RFIL  ++G+I++ N+ + +L   L  +G+ 
Subjt:  GLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFT

Query:  PFPKKTKSVEPEVAGASNETDEAEESPEA-KGERVSDYG----YLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDR
          P K      +      E +E++   EA K + V+D G    YLL + +  LT EK  ELC  R++ + E+E L++ +P  LW +DL    +EL+ ++ 
Subjt:  PFPKKTKSVEPEVAGASNETDEAEESPEA-KGERVSDYG----YLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDR

Query:  NDAQAEEV-----------RKQQRIK-----ANNDVKPKISRNAAPKAPRNSKKTINSETI-----------------------AESMDTTSSSTTMEV-
         + Q E++           +K Q  +         V P+++     +A +  KK I SE                          E    T   TT+   
Subjt:  NDAQAEEV-----------RKQQRIK-----ANNDVKPKISRNAAPKAPRNSKKTINSETI-----------------------AESMDTTSSSTTMEV-

Query:  ---------------------ASNVVVKPKGKAAPRKAPAKKGKVVNHNDED--DDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQVGAAAKKKEPS
                              SN  V P+ K   R A   K  V   +DED  D DE    +D + +   D+SP ++E S   T         K+ +P 
Subjt:  ---------------------ASNVVVKPKGKAAPRKAPAKKGKVVNHNDED--DDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQVGAAAKKKEPS

Query:  KRAPAKKKTTAKSAQ--ISDNDDSDDDDF-EIKEVAPPAAKKGGGRK--AANAKTTKPPAAAKKREAAAG
        K  P+     A  A+  +  +  S   DF  + E   P +KK    K  AA ++++     AKKR A  G
Subjt:  KRAPAKKKTTAKSAQ--ISDNDDSDDDDF-EIKEVAPPAAKKGGGRK--AANAKTTKPPAAAKKREAAAG

P08096 DNA topoisomerase 2

0.0e+00

49.04

Show/hide

Query:  IEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE
        +   YQ+ T  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++VTYVPGLYKIFDEI+VNAADNK RDP+M+++KV +D E N IS++NNG G+P+E
Subjt:  IEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE

Query:  IHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVITKCKEGDNWTKVTFKPDLAKFN
        IH +EK+Y+PELIFG+LLTSSNYDD  KK TGGRNGYGAKL NIFSTEFV+ETAD +R KKYKQ + DNM +KSEPVIT  K+ D +TK+TFKPDLAKF 
Subjt:  IHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVITKCKEGDNWTKVTFKPDLAKFN

Query:  MTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNSIATIKGGTHV
        M  ++DD+V+++K+R+ DMAG + +T KV LN +R+ +  F+ YV++YL S +    EPP+  +   N+RW++   +S+GQF+QVSFVN+I+TI+GGTHV
Subjt:  MTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNSIATIKGGTHV

Query:  DYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNVASKSGIMDSVLSWVNFKQSKDLKKT
        +Y+ N+I + +  VV K+NK A VKA  +K+Y+ VF+N  I+NP+FDSQTKETLT + S+FGS C L+ +FLK +  KS +++ VL +   K  + L K 
Subjt:  DYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNVASKSGIMDSVLSWVNFKQSKDLKKT

Query:  DGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNVKP
        DG    +I+G+ KLEDAN AG + S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  QI  NKEIQ IK+I+G    K Y +VK 
Subjt:  DGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNVKP

Query:  LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREY
        LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T R   V +FYT+PEYE WKE+   N  GW IKYYKGLGTS   + + Y
Subjt:  LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREY

Query:  FEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFI
        F  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T+  I   DF+N+ELI FSMAD  RSIPSVVDGLKPGQRK+++  FKRN +
Subjt:  FEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFI

Query:  KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDRLLNYLNEDGQSIEPT
         E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLL+PNGQFGTR+ GGK+ ++SRY+ T LS + R LF  +DD+LLNY N++GQ IEP 
Subjt:  KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDRLLNYLNEDGQSIEPT

Query:  WYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVSGIIEEVSDTTLRITELPVRRWTNDY
        +Y+PI+P VLVNG+EGIGTGWS+++PNYNP+DI  N++ +L+GE +  M PWY+GF G+I K A       Y +SGII ++ +  + ITELP+R WT D 
Subjt:  WYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSYTVSGIIEEVSDTTLRITELPVRRWTNDY

Query:  KEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEY
        KE+L+     A     EK  K  FI   + H  +  V  +V LTE  M  AL E L+ KFKL+ T +TSNM  FDA+G IKKYD+ E IL EF+ +RL  
Subjt:  KEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEY

Query:  YEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAGASNETDEAEESPEAKGERVSD-YGYLLAL
        Y++RK +++  LE+   +  N+ RFI  ++ GE+VVS +++ DL  EL+ K F P   PKK   V+ EV    N   E E+S +   +  SD Y YLL++
Subjt:  YEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAGASNETDEAEESPEAKGERVSD-YGYLLAL

Query:  AIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQ--RIKANNDVKPKISRNAAPKAPRNSKKTINSETIA
         + +LT E+  EL   +D++  E++ L K TPK LWL DLD  E   +++  +D Q E + ++Q  R   N   K    ++   + PR    + +S  + 
Subjt:  AIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQ--RIKANNDVKPKISRNAAPKAPRNSKKTINSETIA

Query:  ESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQVGAAAKK--KEPSKRAPAKK
        +   + S  +T       ++    + A  K P K   +     ED+   +   ++R++      S D  +       V    A +KK  K+ +  A  + 
Subjt:  ESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQVGAAAKK--KEPSKRAPAKK

Query:  KTTAKSAQISDNDDSDDDDFEIKEVAP------PAAKKGGGRKAANAKTTKP
        + T K    +     D+DD     + P       A+ K  G+KA++ K   P
Subjt:  KTTAKSAQISDNDDSDDDDFEIKEVAP------PAAKKGGGRKAANAKTTKP

P30182 DNA topoisomerase 2

0.0e+00

64.6

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Query:  KRPLQNSTVANVDSAPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNS  ANV  APA  +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSTVANVDSAPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        SV+VVIDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKR KKYKQVF +NMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV
        PVITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  +TE P  R   K N+RWE+ 
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKN
        V+LSEGQFQQVSFVNSIATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKN

Query:  VASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGG+NS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y NV  LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  LG HKKDFVW+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADL

Query:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPS+VDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSY
         VTR LFP+DDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NV+RLL+GE+M+PMDPWY+GF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSY

Query:  TVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMH
        T++G+ EEV +TT+RITELP+RRW +DYK FL S+     K D       PF +    ++D+K+V  D+ L+EENM+ A QEG  KKFKLTTT++TSNMH
Subjt:  TVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASN
        LFD  GVIKKY TPEQILEEFF LR EYYEKRK  +++N+E ELL+LENK RFILAV++GEI+V+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASN

Query:  ETDEAEE------SPEAKGERV--SDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEV--RKQQR
        + D AEE       PE+    +  S+Y YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL++L+KEL+++D  DAQ ++     Q++
Subjt:  ETDEAEE------SPEAKGERV--SDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEV--RKQQR

Query:  IKANNDVKPKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV--VVKPKGK-AAPRKAPAKKGKVVNHNDEDDDDEVLEL---KDRLAAYK
        I+A +    K+ R  APK P   K T   +  +ES  T +S + M+  +NV  VVKPK +  A +KA   +    +H+  D D+ V E+   K R  A K
Subjt:  IKANNDVKPKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV--VVKPKGK-AAPRKAPAKKGKVVNHNDEDDDDEVLEL---KDRLAAYK

Query:  IDSSPDRSEVSAMETEVPQVGAAAKKKEPSK--RAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLG
              ++  +A E E  ++   A++        APA    TA++++    DD DDD   + EVAP    K GGRK A  K  KPPAA +KR       G
Subjt:  IDSSPDRSEVSAMETEVPQVGAAAKKKEPSK--RAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLG

Query:  QKLI--TQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSD
        ++ +  T++L      G+SPEKKVRKMR+SPFNKKS S++ R+ + +EEE  EN     + G++SS   E+S G + A  R QRANR ++ YV+SDS+S+
Subjt:  QKLI--TQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSD

Query:  PV--YEGDDKDDDFDDE
             E DD +DD DDE
Subjt:  PV--YEGDDKDDDFDDE

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

46.96

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Query:  EKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N  V    ++ A   K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR V++VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVI
        VVID E+  ISV N+G G+P+++H E K+Y+PELIFG+LLTSS+YDD+ K+ TGGRNG+GAKL NIFST+F++E AD K +K YKQ F +NM  K +P I
Subjt:  VVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVI

Query:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS
        T  +   ++TK+TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + ++SF+ Y++LY       +   PK Y+ K ++RWE+ VTLS
Subjt:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS

Query:  -EGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNVA
         E QF QVSFVNSI T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDSQTKETLT + SSFGS CE + +F+K V 
Subjt:  -EGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNVA

Query:  -SKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         SKSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K 
Subjt:  -SKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKES
        +  N EI  I  ILGL+ GK Y  +  LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+LLR+P FLVEFITPIVK    N   +SFYTMPE+  W+E+
Subjt:  ITENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQ-TEKLIKYSDFVNKELILFSMADL
           N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + ++RK W+     GT L+Q   K + YSDF+NKEL+LFS+AD 
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQ-TEKLIKYSDFVNKELILFSMADL

Query:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMAQ+FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+
Subjt:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIE-KTATKEGGVS
        ++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWSS +PNYNPRD+I N++  +DG+ + P+ PWY+GF G+IE    +K  G  
Subjt:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIE-KTATKEGGVS

Query:  YTVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSV----TRVATKNDKEK--------AAKDPFIEQADHHSDD--------KTVSIDVHLTEENMILA
        Y   GI +++SD    ITELP+  WT DY+E LD +    TR   K +KEK         AK    +++    DD         TV    + + E+ I  
Subjt:  YTVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSV----TRVATKNDKEK--------AAKDPFIEQADHHSDD--------KTVSIDVHLTEENMILA

Query:  L--------QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVD
        +        +  ++K FKL +T++ +NM +FD  G I+++ T   + E FFPLR+++Y+ RK  L E L  E  +L NK RFILAVVN E+V+SN ++VD
Subjt:  L--------QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVD

Query:  LFHELQAKGFTPF------------PKKTKSVEPEVAGASNETDEAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKS
        L ++L+   F                KK K+   E   A +  +E + + E + +    Y YLL+L + +LT+E+V++L  +RD  K E + L     + 
Subjt:  LFHELQAKGFTPF------------PKKTKSVEPEVAGASNETDEAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKS

Query:  LWLKDLDTLEKELDEMDRNDA----QAEEVRKQQRIKA---NNDVKPKISRNA--AP---------KAPRNSKKTINSETIAESMDTTSSSTTMEVASNV
        ++ +DLD LEK LD+ D  D     Q E ++K+ + KA      +  K+ ++   AP         K P  +   ++     +S DTTS+ST+   +SN 
Subjt:  LWLKDLDTLEKELDEMDRNDA----QAEEVRKQQRIKA---NNDVKPKISRNA--AP---------KAPRNSKKTINSETIAESMDTTSSSTTMEVASNV

Query:  VVKP------KGKAAPRKAPAKKGKVVNHNDED-DDDEVLELKDRLAAYKI----------DSSPDRSEVSAMETEVPQVGAAAKKKEPSKRAPAKKKTT
          KP      K    P  A  K   V   +D D DDD V+  K +    K           D   D+      + E P   + A  K+P+  A  KK TT
Subjt:  VVKP------KGKAAPRKAPAKKGKVVNHNDED-DDDEVLELKDRLAAYKI----------DSSPDRSEVSAMETEVPQVGAAAKKKEPSKRAPAKKKTT

Query:  AKSAQISDNDDSDD
        +KS  I D    D+
Subjt:  AKSAQISDNDDSDD

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

4.7e-25

25.16

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Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNY--DDTVKKTTGGRNGYGAKLTNIFSTEF
        GL+ +  EIL NA D  Q       + VV+  + + +S+ +NG G+P ++H        E +   L     +    +    +GG +G G  + N  S   
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNY--DDTVKKTTGGRNGYGAKLTNIFSTEF

Query:  -VIETADGKR-QKKYKQVFCDNMGKKSEPVIT-KC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVK
         VI   DG   Q+KY          + +PV T  C        G   T + F PD   F      + + +A   + +  +   +  ++K E +     V 
Subjt:  -VIETADGKR-QKKYKQVFCDNMGKKSEPVIT-KC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVK

Query:  SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVK
        S   Y     +  S   T+  K  H     R EI  +  +   Q          + + NSI TI GGTH++ +   +    +N + KK K   VK + + 
Subjt:  SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVK

Query:  SYLWV-------------------------------------FINALIDNPAFDSQTKETL---TIR-------QSSFGSGCELTPEFLKNVASKSGIMD
        S  W+                                      ++  + NP F+ QTK  L    +R       Q       EL P+ L+++ SKS  ++
Subjt:  SYLWV-------------------------------------FINALIDNPAFDSQTKETL---TIR-------QSSFGSGCELTPEFLKNVASKSGIMD

Query:  SVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQY
        +  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EIQ 
Subjt:  SVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQY

Query:  IKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWS
        +   LGL    E  N + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y     +    S  GNAS ++
Subjt:  IKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWS

Query:  IKYYKGLG
        I+ +KGLG
Subjt:  IKYYKGLG

AT3G10690.1 DNA GYRASE A

9.4e-10

27.54

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Query:  LQRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSE--HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        L R++P V DGLKP  R+ILF   +     +    + +  V E     + HG+ ++  +++ MAQ F  S    L+  +G FG+ +      A+ RY   
Subjt:  LQRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSE--HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTR--FLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII
        +L  +     L   D D +    N D    EP      +P +L+NG+ GI  G ++ +P +N  +++
Subjt:  KLSNVTR--FLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII

AT3G23890.1 topoisomerase II

0.0e+00

64.6

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Query:  KRPLQNSTVANVDSAPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNS  ANV  APA  +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSTVANVDSAPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        SV+VVIDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKR KKYKQVF +NMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV
        PVITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  +TE P  R   K N+RWE+ 
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKN
        V+LSEGQFQQVSFVNSIATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKN

Query:  VASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGG+NS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y NV  LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  LG HKKDFVW+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADL

Query:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPS+VDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSY
         VTR LFP+DDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NV+RLL+GE+M+PMDPWY+GF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSY

Query:  TVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMH
        T++G+ EEV +TT+RITELP+RRW +DYK FL S+     K D       PF +    ++D+K+V  D+ L+EENM+ A QEG  KKFKLTTT++TSNMH
Subjt:  TVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASN
        LFD  GVIKKY TPEQILEEFF LR EYYEKRK  +++N+E ELL+LENK RFILAV++GEI+V+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASN

Query:  ETDEAEE------SPEAKGERV--SDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEV--RKQQR
        + D AEE       PE+    +  S+Y YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL++L+KEL+++D  DAQ ++     Q++
Subjt:  ETDEAEE------SPEAKGERV--SDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEV--RKQQR

Query:  IKANNDVKPKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV--VVKPKGK-AAPRKAPAKKGKVVNHNDEDDDDEVLEL---KDRLAAYK
        I+A +    K+ R  APK P   K T   +  +ES  T +S + M+  +NV  VVKPK +  A +KA   +    +H+  D D+ V E+   K R  A K
Subjt:  IKANNDVKPKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV--VVKPKGK-AAPRKAPAKKGKVVNHNDEDDDDEVLEL---KDRLAAYK

Query:  IDSSPDRSEVSAMETEVPQVGAAAKKKEPSK--RAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLG
              ++  +A E E  ++   A++        APA    TA++++    DD DDD   + EVAP    K GGRK A  K  KPPAA +KR       G
Subjt:  IDSSPDRSEVSAMETEVPQVGAAAKKKEPSK--RAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLG

Query:  QKLI--TQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSD
        ++ +  T++L      G+SPEKKVRKMR+SPFNKKS S++ R+ + +EEE  EN     + G++SS   E+S G + A  R QRANR ++ YV+SDS+S+
Subjt:  QKLI--TQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSD

Query:  PV--YEGDDKDDDFDDE
             E DD +DD DDE
Subjt:  PV--YEGDDKDDDFDDE

AT3G23890.2 topoisomerase II

0.0e+00

64.81

Show/hide

Query:  KRPLQNSTVANVDSAPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNS  ANV  APA  +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSTVANVDSAPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE
        SV+VVIDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKR KKYKQVF +NMGKKSE
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSE

Query:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV
        PVITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  +TE P  R   K N+RWE+ 
Subjt:  PVITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKN
        V+LSEGQFQQVSFVNSIATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNSIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKN

Query:  VASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGG+NS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y NV  LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  LG HKKDFVW+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADL

Query:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPS+VDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSY
         VTR LFP+DDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NV+RLL+GE+M+PMDPWY+GF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKGFSGTIEKTATKEGGVSY

Query:  TVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMH
        T++G+ EEV +TT+RITELP+RRW +DYK FL S+     K D       PF +    ++D+K+V  D+ L+EENM+ A QEG  KKFKLTTT++TSNMH
Subjt:  TVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASN
        LFD  GVIKKY TPEQILEEFF LR EYYEKRK  +++N+E ELL+LENK RFILAV++GEI+V+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASN

Query:  ETDEAEE------SPEAKGERV--SDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEV--RKQQR
        + D AEE       PE+    +  S+Y YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL++L+KEL+++D  DAQ ++     Q++
Subjt:  ETDEAEE------SPEAKGERV--SDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEV--RKQQR

Query:  IKANNDVKPKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV--VVKPKGK-AAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDS
        I+A +    K+ R  APK P   K T   +  +ES  T +S + M+  +NV  VVKPKG+  A +KAPA   +V       ++DE+L+L  RLA Y   S
Subjt:  IKANNDVKPKISRNAAPKAPRNSKKTINSETIAESMDTTSSSTTMEVASNV--VVKPKGK-AAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDS

Query:  SPDRSEVSAMETEVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLI-
                                     APA    TA++++    DD DDD   + EVAP    K GGRK A  K  KPPAA +KR       G++ + 
Subjt:  SPDRSEVSAMETEVPQVGAAAKKKEPSKRAPAKKKTTAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLI-

Query:  -TQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPV--Y
         T++L      G+SPEKKVRKMR+SPFNKKS S++ R+ + +EEE  EN     + G++SS   E+S G + A  R QRANR ++ YV+SDS+S+     
Subjt:  -TQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEENGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPV--Y

Query:  EGDDKDDDFDDE
        E DD +DD DDE
Subjt:  EGDDKDDDFDDE

AT5G04130.1 DNA GYRASE B2

1.2e-28

24.76

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Query:  EMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQE
        E  Q    L+ +  RP  Y+GS                     T   GL+ +  EIL NA D  Q   +   V VV+  +   +SV +NG G+P ++H  
Subjt:  EMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQE

Query:  EKVYVPELIFGHLLTSSNYDDTVK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVIT-KCK------EGDNWTKVTFKPD
         K    E +   L     +  T      +GG +G G  + N  S    +E +  +   ++KQ +      + +P+ T  C+      +G   T + F PD
Subjt:  EKVYVPELIFGHLLTSSNYDDTVK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVIT-KCK------EGDNWTKVTFKPD

Query:  LAKFNMT-HLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QV
           F      + + +A   + +  +   +  ++K E +       S   +     +  S   T+     H     R EI     +   Q          +
Subjt:  LAKFNMT-HLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQ---------QV

Query:  SFVNSIATIKGGTHVDYITNQIANYVMNVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGSGCELTPEF
         + NSI TI GGTH++ +   +   +  +  K    K K+ ++   +V+  L   ++  + NP F+ QTK  L    +R       Q       EL P+ 
Subjt:  SFVNSIATIKGGTHVDYITNQIANYVMNVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGSGCELTPEF

Query:  LKNVASKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS
        L+++ SKS  +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+    
Subjt:  LKNVASKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS

Query:  SKQITENKEIQYIKQILGLQQGKEYNNVKP--LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE
           + +N+EIQ +  ILGL  G +  + K   LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y   + +
Subjt:  SKQITENKEIQYIKQILGLQQGKEYNNVKP--LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE

Query:  SWKESLRGNASGWSIKYYKGLG
            +   NAS ++I+ +KGLG
Subjt:  SWKESLRGNASGWSIKYYKGLG

Sequences

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CDS sequence

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ATGGCCGTGGAGAAGAAGCGCCCATTACAGAACAGCACCGTTGCCAATGTCGACTCCGCTCCGGCGGGGCCGAAGAAAACAATCGAAGAAATGTACCAGAAGAAGACTCA
GCTCGAGCACATTCTCCTCAGACCGGATACGTATGTCGGATCAATTGAAAAGCACACTCAAAACCTCTGGGTTTACGAGAACGACAAGATGGTGCACCGATCCGTTACCT
ACGTTCCTGGCCTCTACAAGATCTTCGATGAAATTTTAGTCAATGCTGCAGATAACAAGCAGAGAGACCCCTCGATGGACTCGGTCAAGGTTGTGATTGATGTCGAACAG
AACTGTATCAGTGTGTTCAACAATGGAGATGGAGTTCCTGTGGAGATTCATCAGGAGGAGAAGGTTTATGTGCCTGAATTGATCTTTGGCCATCTGTTGACTAGTAGTAA
TTATGATGACACTGTGAAGAAAACCACTGGTGGACGCAACGGCTACGGTGCAAAACTTACGAATATTTTTTCCACTGAGTTCGTCATCGAGACCGCGGATGGAAAACGCC
AGAAGAAGTATAAGCAGGTATTCTGTGACAACATGGGGAAAAAATCCGAGCCTGTCATAACGAAGTGCAAGGAGGGCGATAATTGGACCAAGGTGACTTTTAAGCCAGAC
TTGGCGAAGTTCAATATGACGCATCTTGAAGATGATGTTGTTGCACTGATGAAAAAGCGGGTGTTGGATATGGCCGGATGCCTCGGCAAAACCGTGAAGGTTGAGCTGAA
TGGACAAAGAGTCCCTGTTAAATCATTTCAAGATTATGTAGATCTCTACCTCAAATCGGCTTCCACATTCCAGACAGAGCCCCCAAAAAGGTATCACATTAAGCCTAACG
AGAGATGGGAAATCGTGGTGACTTTAAGTGAGGGGCAGTTCCAGCAGGTCAGCTTTGTGAACAGTATTGCAACTATAAAGGGTGGGACTCATGTTGATTACATCACTAAT
CAGATAGCAAATTATGTGATGAATGTTGTAAATAAGAAGAACAAAAATGCTAACGTGAAAGCCCACAACGTGAAGAGTTATTTGTGGGTTTTTATCAACGCTCTCATTGA
TAATCCTGCCTTCGACTCCCAAACCAAGGAAACTTTGACAATTCGTCAAAGCAGTTTCGGTTCTGGATGCGAACTGACACCAGAGTTTTTGAAGAATGTTGCCTCGAAAT
CTGGAATTATGGACAGCGTTCTCTCGTGGGTTAATTTCAAGCAAAGCAAAGACCTGAAGAAAACTGATGGAGCAAAAACTGAAAAAATCAGTGGTATCGAAAAGTTGGAG
GATGCCAATTGCGCTGGAGGGAGGAACTCGGAAAAATGTACCTTGATTTTGACAGAAGGAGATTCAGCGAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTGGGACGAGA
CTTCTATGGCGTATTCCCACTTAGAGGTAAATTGCTGAATGTGAGGGAAGCGAGTAGCAAACAGATCACAGAGAATAAAGAAATTCAGTACATTAAGCAGATTCTTGGAC
TTCAACAAGGGAAGGAATACAACAATGTCAAGCCTTTGAGATATGGTCATTTGATGATAATGACCGATCAGGATCATGATGGTTCACATATTAAAGGACTCTTGATCAAC
TTTATTCATTCTTTCTGGCCTTCCCTCCTAAGGGTACCGTCTTTCTTGGTTGAGTTCATAACGCCAATTGTCAAGGCTACTCATAGGAATGGAACTGTTTTATCATTCTA
TACCATGCCCGAGTACGAGTCCTGGAAAGAAAGCTTGAGGGGCAATGCAAGTGGGTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCAAAAGAAGGAAGAG
AGTACTTTGAACAGCTGGGAAAGCACAAGAAAGATTTTGTTTGGCAAGATGACCATGATGGGGAGGCAATTGAACTTGCATTCAGTAAGAAGAAGATTGAAGAGAGGAAG
AATTGGCTCCGCCATTTTGAGCCTGGTACCCATCTAGATCAGACAGAAAAATTGATAAAATACAGTGACTTTGTCAACAAGGAGCTTATATTATTTTCAATGGCTGATTT
ACAAAGGTCTATTCCTTCAGTGGTTGATGGCCTCAAGCCTGGCCAGAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACTTTATCAAAGAAGCCAAAGTTTCTCAATTTT
CCGGTTATGTATCTGAGCATTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGACTTTGTCGGCAGCAACAACATTAATCTTCTT
CTGCCAAATGGACAGTTTGGGACCCGGAACCATGGAGGCAAAGATCATGCGAGTTCTAGGTACATTTACACTAAGCTTTCAAATGTTACACGGTTTCTTTTCCCGAGAGA
CGATGACAGGCTTCTTAACTACTTGAACGAAGACGGCCAGTCGATTGAACCAACCTGGTATATGCCTATCATACCAACGGTTCTTGTCAACGGAAGTGAAGGAATTGGAA
CTGGGTGGAGTTCGTACGTTCCAAATTATAATCCTAGAGATATCATTACAAATGTAAAACGTTTATTAGATGGTGAAACGATGATGCCCATGGATCCCTGGTATAAAGGT
TTTTCAGGAACTATAGAGAAAACTGCTACCAAGGAAGGAGGTGTTAGTTACACTGTCAGTGGAATTATAGAGGAAGTCAGCGATACAACGTTGAGAATAACTGAACTGCC
AGTCCGCCGGTGGACTAATGATTATAAGGAATTTCTTGATTCTGTCACGAGAGTTGCAACAAAGAATGACAAAGAAAAAGCAGCGAAAGATCCTTTTATTGAGCAAGCTG
ATCACCACAGCGATGACAAAACTGTATCCATCGATGTCCACTTAACGGAGGAAAACATGATACTGGCCCTGCAGGAGGGTCTGAAGAAAAAATTCAAACTAACTACTACT
GTCAGCACAAGCAACATGCACCTGTTTGATGCAAATGGTGTGATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTTCCCCTTAGACTTGAATATTATGA
GAAAAGAAAGATGAATCTCTTGGAAAACCTTGAAAGGGAGTTGCTTCAACTGGAAAACAAGGTTAGGTTCATCCTGGCTGTTGTGAATGGAGAGATAGTAGTGAGCAATA
GAAGAAGAGTTGATTTATTCCATGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCGAAGAAGACTAAATCTGTTGAGCCGGAGGTTGCTGGGGCATCTAATGAAACTGAT
GAAGCAGAGGAAAGCCCGGAGGCGAAAGGGGAGCGGGTTAGCGACTATGGGTATCTACTGGCACTGGCAATCGGAACCTTGACCATTGAGAAGGTTCAGGAGCTATGTAA
CGACAGAGACAAGCTCAAAGGGGAAGTGGAAGATCTGAGGAAAGCAACCCCCAAGTCTTTGTGGCTGAAAGATCTTGATACTCTTGAGAAGGAGCTTGATGAAATGGATA
GAAATGATGCTCAGGCAGAGGAGGTAAGAAAACAACAGAGAATCAAAGCAAATAACGATGTAAAGCCAAAGATCTCTAGGAATGCTGCACCAAAAGCTCCACGTAACAGT
AAGAAAACCATCAATTCAGAGACCATCGCGGAAAGTATGGACACAACATCTAGTTCTACAACCATGGAAGTTGCTAGTAACGTGGTGGTGAAGCCCAAAGGCAAAGCAGC
TCCAAGAAAAGCTCCTGCTAAGAAGGGTAAAGTTGTCAACCATAACGACGAAGACGACGACGATGAAGTGCTTGAGCTTAAAGATCGTCTTGCAGCTTACAAAATTGATT
CGTCTCCCGATCGATCAGAAGTTTCAGCCATGGAAACTGAAGTGCCACAAGTAGGAGCGGCGGCCAAGAAGAAGGAACCCAGTAAGAGAGCACCTGCCAAGAAGAAAACT
ACTGCAAAGTCGGCTCAGATTTCCGATAACGACGACAGCGACGACGACGACTTTGAAATAAAGGAGGTAGCCCCTCCGGCAGCCAAGAAGGGAGGAGGGAGAAAGGCTGC
AAATGCCAAAACCACGAAACCCCCGGCGGCAGCCAAGAAGCGAGAGGCGGCGGCGGGAAAGTTGGGGCAGAAGCTGATAACTCAAATGCTGGGGCCGACGCAGAACTCCG
GCATCTCGCCGGAGAAGAAAGTGAGGAAGATGAGAGCATCTCCCTTCAACAAGAAAAGCGGCTCCATCTTGGGAAGAGTTGGGGAAGAGGAAGAAGAAGAAGGAGAAGAA
AATGGAAATGAAGGGAAGATTATGGGTTCTGCTTCTTCCGAGACGGCTGAAGAATCCGCCGGATTTCTGCCGGCCAGAGGAAGATCACAGAGGGCAAATAGAACTCAGGT
GAAGTATGTAATCAGTGACTCAGATAGTGACCCAGTTTATGAGGGTGATGATAAAGATGACGATTTTGATGATGAAGAT

mRNA sequence

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Protein sequence

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MAVEKKRPLQNSTVANVDSAPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQ
NCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFCDNMGKKSEPVITKCKEGDNWTKVTFKPD
LAKFNMTHLEDDVVALMKKRVLDMAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNSIATIKGGTHVDYITN
QIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSGCELTPEFLKNVASKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLE
DANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNVKPLRYGHLMIMTDQDHDGSHIKGLLIN
FIHSFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFVWQDDHDGEAIELAFSKKKIEERK
NWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL
LPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDRLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIITNVKRLLDGETMMPMDPWYKG
FSGTIEKTATKEGGVSYTVSGIIEEVSDTTLRITELPVRRWTNDYKEFLDSVTRVATKNDKEKAAKDPFIEQADHHSDDKTVSIDVHLTEENMILALQEGLKKKFKLTTT
VSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEYYEKRKMNLLENLERELLQLENKVRFILAVVNGEIVVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETD
EAEESPEAKGERVSDYGYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDTLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPKISRNAAPKAPRNS
KKTINSETIAESMDTTSSSTTMEVASNVVVKPKGKAAPRKAPAKKGKVVNHNDEDDDDEVLELKDRLAAYKIDSSPDRSEVSAMETEVPQVGAAAKKKEPSKRAPAKKKT
TAKSAQISDNDDSDDDDFEIKEVAPPAAKKGGGRKAANAKTTKPPAAAKKREAAAGKLGQKLITQMLGPTQNSGISPEKKVRKMRASPFNKKSGSILGRVGEEEEEEGEE
NGNEGKIMGSASSETAEESAGFLPARGRSQRANRTQVKYVISDSDSDPVYEGDDKDDDFDDED

MS016089 (gene) of Bitter gourd (TR) v1 genome