CuGenDBv2

Gene ID	MS016495
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog
Genome location	scaffold657:114028..119086
RNA-Seq Expression	MS016495
Synteny	MS016495
Gene Ontology terms	GO:0006203 - dGTP catabolic process (biological process) GO:0005634 - nucleus (cellular component) GO:0005524 - ATP binding (molecular function) GO:0008832 - dGTPase activity (molecular function)
InterPro domains	IPR003607 - HD/PDEase domain IPR006674 - HD domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022158922.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X1 [Momordica charantia]

1.8e-243

88.96

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL               +   GA+HMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDHCDIQTVKLAG LLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV             KGSRAKGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVK---AIELMLVDALLKANDYLEISSH
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVK   AIELMLVDALLKANDYLEISSH
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVK---AIELMLVDALLKANDYLEISSH

Query:  IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLD
        IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLD
Subjt:  IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLD

Query:  RLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
        R+              F +DYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
Subjt:  RLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

XP_022158924.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X2 [Momordica charantia]

4.2e-245

89.51

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL               +   GA+HMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDHCDIQTVKLAG LLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV             KGSRAKGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDR+ 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

XP_022989158.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog [Cucurbita maxima]

1.4e-229

83.74

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGAS+ DELSLAPVH+FNSSFQDLRC KHVHDNVHGNIYLDPL               +   G THMVYPGAVHSRFEHSLGVYWLA EA++KL+ YQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDH DIQTVKLAG LLHDVGHGPFSHLFEREF+PQV S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRV             KGSR KGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLT+HKLF+TRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PSQYWKLDD++VKTIETA DQELKESRDLIL+IRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPL+R+ 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATPEKKKRRI
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

XP_023531708.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X1 [Cucurbita pepo subsp. pepo]

2.5e-229

83.57

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGAS+ DELSLAPVH+FNSSFQDLRC KHVHDNVHGNIYLDPL               +   G THMVYPGAVHSRFEHSLGVYWLA EA++KL+ YQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRVK--------------GSRAKGFLYDI
        ELDIDH DIQTVKLAG LLHDVGHGPFSHLFEREF+PQV S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRVK              GSR KGFLYDI
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRVK--------------GSRAKGFLYDI

Query:  VANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIH
        VANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLT+HKLF+TRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIH
Subjt:  VANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIH

Query:  DPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRL
        DPSQYWKLDD++VKTIETA DQELKESRDLIL+IRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPL+R+
Subjt:  DPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRL

Query:  LRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                      F +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATPEKKKRRI
Subjt:  LRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

XP_023531709.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X2 [Cucurbita pepo subsp. pepo]

1.9e-229

83.74

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGAS+ DELSLAPVH+FNSSFQDLRC KHVHDNVHGNIYLDPL               +   G THMVYPGAVHSRFEHSLGVYWLA EA++KL+ YQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDH DIQTVKLAG LLHDVGHGPFSHLFEREF+PQV S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRV             KGSR KGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLT+HKLF+TRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PSQYWKLDD++VKTIETA DQELKESRDLIL+IRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPL+R+ 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATPEKKKRRI
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

TrEMBL top hits

e value

%identity

Alignment

A0A5A7UIY3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like protein isoform X1

2.9e-220

80.45

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGASLNDEL L PV +FNSS  D+R  KHVHDNVHGNIYLDPL               +   G THMVYPGAVHSRFEHSLGVYWLAG+A+QKLKNYQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDID  DIQTVKLAG LLHDVGHGPFSHLFEREF+ +V S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRV             KGS+ KGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNF F+RLM+TMRVIDDEICYKA DYLT+HKLFATRADLYRTVY HPKVKAIELM+VDALLKANDYL++SS+IHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PS+YWKLDD+IVKTIETA D+ELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGV L+EEDVAVSNVRIDLTRGR NPL+R+ 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATP+KKKRRI
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

A0A6J1DYF2 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X1

8.5e-244

88.96

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL               +   GA+HMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDHCDIQTVKLAG LLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV             KGSRAKGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVK---AIELMLVDALLKANDYLEISSH
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVK   AIELMLVDALLKANDYLEISSH
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVK---AIELMLVDALLKANDYLEISSH

Query:  IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLD
        IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLD
Subjt:  IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLD

Query:  RLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
        R+              F +DYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
Subjt:  RLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

A0A6J1E0V4 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog isoform X2

2.0e-245

89.51

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL               +   GA+HMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDHCDIQTVKLAG LLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV             KGSRAKGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDR+ 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

A0A6J1EJX3 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog

1.3e-228

83.33

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGAS+ DELSLAPVH+FNSSFQDLRC KHVHDNVHGNIYLDPL               +   G THMVYPGAVHSRFEHSLGVYWLA EA++KL+ YQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDH DIQTVKLAG LLHDVGHGPFSHLFEREF+P+V S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRV             KGSR KGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNF FQRLMETMRVIDDEICYKAKDYLT+HKLF+TRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PSQYWKLDD++VKTIETA DQELKESRDLIL+IRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPL+R+ 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATPEKKKRRI
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

A0A6J1JPF8 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog

7.0e-230

83.74

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Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGAS+ DELSLAPVH+FNSSFQDLRC KHVHDNVHGNIYLDPL               +   G THMVYPGAVHSRFEHSLGVYWLA EA++KL+ YQGA
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        ELDIDH DIQTVKLAG LLHDVGHGPFSHLFEREF+PQV S YEWSHELMSVKMVD++VDEHHIDIDSGMIKRV             KGSR KGFLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLT+HKLF+TRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PSQYWKLDD++VKTIETA DQELKESRDLIL+IRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGV+LQE+DVAVSNVRIDLTRGRNNPL+R+ 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DYES++KFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLK YGIKTQVHATPEKKKRRI
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

SwissProt top hits

e value

%identity

Alignment

B0G107 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog

3.4e-72

35.75

Show/hide

Query:  HDFNSSFQDLRCFKHVHDNVHGNI----YLDPLVTCS-----------GATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKL
        +D ++ +   +  K ++D +HG++    Y+   +              G T  V+P A HSRFEHS+GV  LAG+ I ++K  Q  EL+I   + + V++
Subjt:  HDFNSSFQDLRCFKHVHDNVHGNI----YLDPLVTCS-----------GATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKL

Query:  AGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHID-IDSGMIKRVKG-------SRAKGFLYDIVANGRNGIDVDKFDYIVRDC
        AG L HD+GHGPFSH FE  ++ Q+     + HE MS+KM+++++D+H +D  DS  IK +          + + F+YDIVAN RN +DVDKFDY+ RD 
Subjt:  AGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHID-IDSGMIKRVKG-------SRAKGFLYDIVANGRNGIDVDKFDYIVRDC

Query:  RACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHDPSQYWKLDDTIVKTIETAP
           G      FQRLME  +VIDD+IC+ +K+   +++LF TR  L++ VY H   K+IE M+ DA  +A+ +L+IS  + DP ++  L D++++ IET+ 
Subjt:  RACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHDPSQYWKLDDTIVKTIETAP

Query:  DQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLLRKFISLQYYNKFGFGQDYE
        + EL++SR +I  IR RNLY+F +E  V  DK+    D  A+DI  ++   G+L  E D+ V N++++      +P+        S ++Y +      Y+
Subjt:  DQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLLRKFISLQYYNKFGFGQDYE

Query:  SDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAF
        S + F I  +  SHL+P  +Q+  +R++ +  E  E +  AF
Subjt:  SDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAF

Q0VCA5 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1.1e-54

31.45

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Query:  KHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGSLLHDVGHGPF
        K ++D +HG+I   PL               +   G  + V+PGA H+RFEHSLGV +LAG  +++L   Q  EL I   DI  V++AG L HD+GHGPF
Subjt:  KHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGSLLHDVGHGPF

Query:  SHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHI-----------DIDSGMIKR-----------------VKG-SRAKGFLYDIVANGRNGIDVDK
        SH+F+  FIP    + +W+HE  SV M +++++ + +           + D   IK                   KG  + K FLY+IVAN RNGIDVDK
Subjt:  SHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHI-----------DIDSGMIKR-----------------VKG-SRAKGFLYDIVANGRNGIDVDK

Query:  FDYIVRDCRACGLGCNFQFQRLMETMRVID----DEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE----------ISSH
        +DY  RDC   G+  +F ++R ++  RV +      IC + K+   ++ +F TR  L+R  Y H     I+ M+ DA LKA+D++E          IS+ 
Subjt:  FDYIVRDCRACGLGCNFQFQRLMETMRVID----DEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE----------ISSH

Query:  IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEY--AVPKDKLENFKDVTAKDIVCSQKNGGVLLQ----EEDVAVSNVRIDLTRG
        I D   + KL D I   I  + D  L ++R ++ +I  RNLY+F  E    + + K EN++ +  +  V S K   V L+     ED+ V  + +D    
Subjt:  IHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEY--AVPKDKLENFKDVTAKDIVCSQKNGGVLLQ----EEDVAVSNVRIDLTRG

Query:  RNNPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPE--LVEAISEAFENFQLKMYGIKTQVHATPEKKKRR
          NP+D        +++Y K       +  +   I+ +++S  LP ++ + ++RVY KK +   + A  + F ++ L     K Q+   P +K ++
Subjt:  RNNPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPE--LVEAISEAFENFQLKMYGIKTQVHATPEKKKRR

Q5ZJL9 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1.1e-59

33.27

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Query:  NSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGS
        N   Q     K  +D VHG+I + PL               +   G T+ V+PGA H+RFEHSLGV +LAG  +++LK  Q  ELDI   DI  V++AG 
Subjt:  NSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGS

Query:  LLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHH-----------IDIDSGMIKRVKGS-----------------RAKGFLYDIVAN
        L HD+GHGPFSH+F+  FIP       W HE  SV+M ++++  +            ++ D   IK   G                  + K FLY+IVAN
Subjt:  LLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHH-----------IDIDSGMIKRVKGS-----------------RAKGFLYDIVAN

Query:  GRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVID----DEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE-----
         +NGIDVDK+DY  RDC   G+  NF ++RL++  RV +      IC + K+   ++ +F TR  L+R  Y H     IE+M+ +A  KA+ + +     
Subjt:  GRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVID----DEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE-----

Query:  -----ISSHIHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNE------YAVPKDKLENFKDVTAKDIVCSQKN---GGVLLQEEDV
             IS+ + D   Y KL D I   I  +   EL E+R+++ +I RR LY+F  E        +PKD+     D  A DI  S+       V L  ED 
Subjt:  -----ISSHIHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNE------YAVPKDKLENFKDVTAKDIVCSQKN---GGVLLQEEDV

Query:  AVSNVRIDLTRGRNNPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKK--PELVEAISEAFENFQLKMYGIKTQ---
         V  V +D      NP+D +L       +Y K       +  +  KIS +++S LLP ++ + ++RVY K+  P +V A  + F  + +K    K Q   
Subjt:  AVSNVRIDLTRGRNNPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKK--PELVEAISEAFENFQLKMYGIKTQ---

Query:  ---VHATPEKK
            H TP K+
Subjt:  ---VHATPEKK

Q60710 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1.7e-55

31.91

Show/hide

Query:  KHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGSLLHDVGHGPF
        K  +D +HG+I   PL               +   G  + V+PGA H+RFEHSLGV +LAG  ++ L   Q  EL I   DI  V++AG L HD+GHGPF
Subjt:  KHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGSLLHDVGHGPF

Query:  SHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDI-----------DSGMIKR---------VKGS--------RAKGFLYDIVANGRNGIDVDKF
        SH+F+  FIP+   + +W HE  S++M +++V+ + + +           D   IK          VK S          K FLY+IV+N RNGIDVDK+
Subjt:  SHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDI-----------DSGMIKR---------VKGS--------RAKGFLYDIVANGRNGIDVDKF

Query:  DYIVRDCRACGLGCNFQFQRLMETMRVIDDE---------------ICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE----
        DY  RDC   G+  NF ++R ++  R+ + E               IC + K+   ++ +F TR  L+R  Y H     I++M+ DA LKA+ Y+E    
Subjt:  DYIVRDCRACGLGCNFQFQRLMETMRVIDDE---------------ICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE----

Query:  ------ISSHIHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNE-----YAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVS
              IS+ I D   + KL D I   +  + D +L E++ ++  I  RNLY++  E       + K++ E      AK     +K   V L+ ED  V 
Subjt:  ------ISSHIHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNE-----YAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVS

Query:  NVRIDLTRGRNNPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPE
         + +D      NP+DR       + +Y K        S +  +I+ +++S LLP  + + ++RVY KK +
Subjt:  NVRIDLTRGRNNPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPE

Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

4.4e-56

33.26

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Query:  KHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGSLLHDVGHGPF
        K ++D +HG+I L PL               +   G  + V+PGA H+RFEHSLGV +LAG  +  L   Q  EL I   D+  V++AG L HD+GHGPF
Subjt:  KHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGSLLHDVGHGPF

Query:  SHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHI-----------DIDSGMIKR----------------VKG-SRAKGFLYDIVANGRNGIDVDKF
        SH+F+  FIP    + +W+HE  SV M +++++ + I           + D   IK                  KG    K FLY+IV+N RNGIDVDK+
Subjt:  SHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHI-----------DIDSGMIKR----------------VKG-SRAKGFLYDIVANGRNGIDVDKF

Query:  DYIVRDCRACGLGCNFQFQRLMETMRV--IDDE--ICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE----------ISSHI
        DY  RDC   G+  NF ++R ++  RV  +D+E  IC + K+   ++ +F TR  L+R  Y H     I+ M+ DA LKA+DY+E          IS+ I
Subjt:  DYIVRDCRACGLGCNFQFQRLMETMRV--IDDE--ICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLE----------ISSHI

Query:  HDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVP---KDKLENFKDVTAKDIVCSQKNG--GVLLQEEDVAVSNVRIDLTRGRN
         D   Y KL D I   I  + D +LK++R+++ +I  RNL+++  E       K K E+++ +  K++  ++      V L+ ED  V  + +D      
Subjt:  HDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVP---KDKLENFKDVTAKDIVCSQKNG--GVLLQEEDVAVSNVRIDLTRGRN

Query:  NPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKK
        NP+D        + +Y K         +   +I+ +++S LLP  + + ++RVY KK
Subjt:  NPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKK

Arabidopsis top hits

e value

%identity

Alignment

AT5G40270.1 HD domain-containing metal-dependent phosphohydrolase family protein

1.5e-187

66.67

Show/hide

Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MGA  ++ LS  PV    +   +LR  KHV+DNVHGNIYLDPL               +   G T+MVYPGAVHSRFEHSLGVYWLAGE  Q+LKN+QG 
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        EL ID+ D+QTV+LAG LLHD+GHGPFSH+FEREF+P+V SD +WSHELMSV M+D+MVD HHIDID+ M+KRV             KG+  K FLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDY+VRD RACGLG NFQFQRL ETMRV+D+EIC++AK+YL+VHKLFATRADLYRTVY H KVKAIELM+VDA++KAN++LEISS I+D
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PS+YWKLDDTI+KTIE APD EL E+++LILR+RRR LYQFCNEYAVPKDK+++FK VT +DI+CSQK+  + L+EED+AV+NV+IDL RGR NPL+ + 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI
                     F +DY+S EKF I +DR+SHLLPT+YQDMIVRVY+KKPELVEA+SEAFENFQ++ YGIK QVHATPEKKKRR+
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQVHATPEKKKRRI

AT5G40290.1 HD domain-containing metal-dependent phosphohydrolase family protein

2.9e-172

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Query:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA
        MG   N++LS  P +       +LR  KHVHDNVHGNIYLDPL               +   G T+MVYPGAVHSRFEHSLGVYWLAGE +Q+LK +QG 
Subjt:  MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPL---------------VTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGA

Query:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV
        EL ID+ D+QTV+LAG LLHD+GHGPFSH+FEREF+P+V S  +WSHELMS+ M+DY+VD HHID+D+ M+KRV             KG+  K FLYDIV
Subjt:  ELDIDHCDIQTVKLAGSLLHDVGHGPFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRV-------------KGSRAKGFLYDIV

Query:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD
        ANGRNGIDVDKFDYIVRD RACGLGCNFQFQRL E MRVID+EICY AK+Y TVHKLFATRADL  TVYMHPK  AIELM+VDA++KAN+ LEISS I+D
Subjt:  ANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKAKDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHD

Query:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL
        PSQYWKLDDTI+KTIE +PD EL E+++LILR+ RR+LYQFCNEYAVPKDK+++FK +T +DI+C          EED+AV+NV+IDL RGR NPL+ + 
Subjt:  PSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDVTAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLL

Query:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQV
                     F +DY S EKF I +DR+SHLLPT+YQ+MIVRVY+KKPELVEA+SEAFENFQ++ YGIK QV
Subjt:  RKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKMYGIKTQV

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGGCGCTTCTCTCAACGACGAACTCTCCCTCGCTCCGGTTCACGACTTCAACTCCTCCTTCCAAGACCTCCGCTGCTTCAAGCACGTCCATGACAACGTCCACGGCAA
CATTTACCTCGATCCGCTTGTTACATGTTCAGGTGCGACGCATATGGTATATCCGGGAGCTGTACATTCTAGGTTTGAACACTCGTTAGGGGTGTATTGGCTTGCTGGAG
AAGCTATTCAAAAGCTTAAGAATTATCAAGGAGCAGAGCTTGATATTGACCACTGTGATATCCAAACAGTGAAGCTTGCTGGTAGCCTTCTGCATGATGTGGGCCATGGG
CCTTTTAGTCACCTGTTTGAACGCGAGTTCATCCCCCAGGTTTTCAGTGACTATGAATGGTCCCATGAACTTATGTCAGTTAAGATGGTTGACTATATGGTTGATGAGCA
CCACATTGATATTGATTCTGGAATGATAAAAAGAGTTAAGGGTTCAAGGGCGAAGGGTTTCCTGTACGACATTGTTGCAAATGGAAGAAATGGAATTGATGTGGACAAGT
TTGATTATATTGTTCGTGATTGTCGAGCTTGTGGTCTAGGATGCAATTTTCAGTTTCAGAGGTTGATGGAGACTATGCGGGTTATTGATGATGAAATTTGCTATAAGGCT
AAGGACTATCTTACTGTTCACAAGTTGTTTGCTACTCGGGCTGATTTGTATCGAACAGTCTATATGCATCCAAAAGTTAAGGCCATTGAGCTTATGCTAGTTGATGCTCT
GTTGAAGGCAAATGATTACCTTGAAATTTCATCCCACATCCATGATCCATCCCAGTACTGGAAGTTAGATGATACCATAGTTAAAACAATTGAGACAGCTCCAGACCAAG
AACTAAAAGAATCGAGAGATTTGATTTTGCGTATCCGAAGAAGAAATCTCTACCAGTTTTGTAATGAATATGCCGTCCCAAAAGACAAACTGGAAAATTTCAAGGATGTA
ACTGCCAAAGATATTGTTTGTTCTCAGAAAAATGGTGGAGTGCTGCTGCAAGAGGAGGATGTTGCTGTCAGCAATGTTAGGATTGACTTGACACGTGGTAGAAATAATCC
TCTTGACAGGTTGTTGAGAAAGTTTATTTCTTTGCAGTATTATAACAAATTCGGTTTTGGACAGGATTATGAAAGCGACGAGAAATTCAAGATCTCTGATGATCGCATAA
GCCATCTACTGCCAACATCATATCAAGATATGATAGTAAGGGTGTACTCCAAGAAACCTGAACTGGTAGAAGCCATCTCAGAAGCATTTGAAAACTTTCAGTTGAAAATG
TATGGGATTAAAACACAAGTTCATGCAACACCGGAGAAGAAGAAACGTCGCATT

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MGASLNDELSLAPVHDFNSSFQDLRCFKHVHDNVHGNIYLDPLVTCSGATHMVYPGAVHSRFEHSLGVYWLAGEAIQKLKNYQGAELDIDHCDIQTVKLAGSLLHDVGHG
PFSHLFEREFIPQVFSDYEWSHELMSVKMVDYMVDEHHIDIDSGMIKRVKGSRAKGFLYDIVANGRNGIDVDKFDYIVRDCRACGLGCNFQFQRLMETMRVIDDEICYKA
KDYLTVHKLFATRADLYRTVYMHPKVKAIELMLVDALLKANDYLEISSHIHDPSQYWKLDDTIVKTIETAPDQELKESRDLILRIRRRNLYQFCNEYAVPKDKLENFKDV
TAKDIVCSQKNGGVLLQEEDVAVSNVRIDLTRGRNNPLDRLLRKFISLQYYNKFGFGQDYESDEKFKISDDRISHLLPTSYQDMIVRVYSKKPELVEAISEAFENFQLKM
YGIKTQVHATPEKKKRRI

MS016495 (gene) of Bitter gourd (TR) v1 genome