CuGenDBv2

Gene ID	MS016793
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	mediator of RNA polymerase II transcription subunit 18
Genome location	scaffold9_1:62420..64046
RNA-Seq Expression	MS016793
Synteny	MS016793
Gene Ontology terms	GO:0006357 - regulation of transcription by RNA polymerase II (biological process) GO:0006369 - termination of RNA polymerase II transcription (biological process) GO:0016592 - mediator complex (cellular component) GO:0070847 - core mediator complex (cellular component) GO:0003712 - transcription coregulator activity (molecular function)
InterPro domains	IPR019095 - Mediator complex, subunit Med18

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008444669.1 PREDICTED: mediator of RNA polymerase II transcription subunit 18 [Cucumis melo]

1.5e-104

97.57

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

XP_011649597.2 mediator of RNA polymerase II transcription subunit 18 isoform X1 [Cucumis sativus]

3.1e-105

98.06

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

XP_022144379.1 mediator of RNA polymerase II transcription subunit 18 [Momordica charantia]

4.3e-107

100

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

XP_022951149.1 mediator of RNA polymerase II transcription subunit 18 [Cucurbita moschata]

6.8e-105

97.09

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRI+CDLEQ EP+WTVKHIGGAMRG+GAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGF+FRFHRG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

XP_038885244.1 mediator of RNA polymerase II transcription subunit 18 [Benincasa hispida]

4.0e-105

97.57

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAVASE+RILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BBM1 mediator of RNA polymerase II transcription subunit 18

7.4e-105

97.57

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

A0A5A7VHE6 Mediator of RNA polymerase II transcription subunit 18

1.3e-104

96.62

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Query:  LQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLD
        ++HVEALEILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLD
Subjt:  LQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLD

Query:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
        HELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
Subjt:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS

Query:  DGAGTTM
        DGAGTTM
Subjt:  DGAGTTM

A0A6J1CS50 mediator of RNA polymerase II transcription subunit 18

2.1e-107

100

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

A0A6J1GHW3 mediator of RNA polymerase II transcription subunit 18

3.3e-105

97.09

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRI+CDLEQ EP+WTVKHIGGAMRG+GAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGF+FRFHRG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

A0A6J1KK74 mediator of RNA polymerase II transcription subunit 18

1.6e-104

96.6

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRI+CDLEQ EP+WTVKHIGGAMRG+GAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGF+FRFHRG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

SwissProt top hits

e value

%identity

Alignment

Q9SJZ6 Mediator of RNA polymerase II transcription subunit 18

8.1e-93

81.07

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQG+CGV RERLR+HE+CL+SGPNLG V+SEVR+LCDL+Q EP WTVKH+GGAMRGAGA+Q+SVLVR M+ESKVSKN LR+FYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATSENYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        G GTT+
Subjt:  GAGTTM

Arabidopsis top hits

e value

%identity

Alignment

AT2G22370.1 unknown protein

5.8e-94

81.07

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQG+CGV RERLR+HE+CL+SGPNLG V+SEVR+LCDL+Q EP WTVKH+GGAMRGAGA+Q+SVLVR M+ESKVSKN LR+FYALGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATSENYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        G GTT+
Subjt:  GAGTTM

Sequences

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CDS sequence

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CTTTGGACTTCTATTGACAGTTTGATTCTGCAGCACGTTGAGGCCCTTGAGATACTTCTTCAAGGTATTTGCGGCGTTCCTAGAGAACGATTGAGACTTCATGAAATATG
CCTAAAAAGTGGACCCAACTTAGGTGCTGTGGCTTCGGAGGTTCGGATCTTGTGTGATCTAGAGCAGGCTGAACCGGCATGGACGGTTAAACATATTGGAGGGGCAATGA
GAGGAGCAGGGGCTGAACAACTCTCTGTTCTGGTTAGGACAATGGTAGAAAGCAAAGTTAGCAAGAATGTGCTTCGTCTATTCTATGCACTTGGCTACAAGTTAGACCAT
GAGCTGCTTAGAGTTGGTTTTGCTTTCCGTTTCCATCGGGGTGCTCACATAACCGTGACGGTTTCATCAGTTAATAAGATGTTAAAGCTACATTCGACGGATGAGGCTGT
GCCTGTAACACCTGGTATACAGCTAGTCGAAGTGACAGCCCCAGCAACTTCTGAAAACTATTCTGAAGTAGCCGGTGCAGTGTCGACTTTCTGTGAATATCTTGCACCCC
TGCTGCATTTGTCGAAACCGGGAATATCCACCGGTGTCGTTCCTACTGCTGCTGCTGCTGCAGCATCTCTCCTATCTGATGGTGCAGGAACAACAATG

mRNA sequence

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Protein sequence

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LWTSIDSLILQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

MS016793 (gene) of Bitter gourd (TR) v1 genome