CuGenDBv2

Gene ID	MS017860
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	chloride conductance regulatory protein ICln
Genome location	scaffold373:3295809..3298224
RNA-Seq Expression	MS017860
Synteny	MS017860
Gene Ontology terms	GO:0000387 - spliceosomal snRNP assembly (biological process) GO:0006821 - chloride transport (biological process) GO:0006884 - cell volume homeostasis (biological process) GO:0045292 - mRNA cis splicing, via spliceosome (biological process) GO:0005681 - spliceosomal complex (cellular component) GO:0005829 - cytosol (cellular component) GO:0005886 - plasma membrane (cellular component) GO:0034709 - methylosome (cellular component) GO:0034715 - pICln-Sm protein complex (cellular component)
InterPro domains	IPR011993 - PH-like domain superfamily IPR039924 - ICln/Lot5

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0055130.1 chloride conductance regulatory protein ICln isoform X1 [Cucumis melo var. makuwa]

2.1e-34

72.45

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y +R  +  GLP FDV+QGEVLMH++PA+ +VFDNR PEFPGTLYVSSRQ+VWLSDA   KG+A+DFLSMSLHAVS DP+AYP PCLYVQ+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

XP_008467268.1 PREDICTED: chloride conductance regulatory protein ICln isoform X1 [Cucumis melo]

2.1e-34

72.45

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y +R  +  GLP FDV+QGEVLMH++PA+ +VFDNR PEFPGTLYVSSRQ+VWLSDA   KG+A+DFLSMSLHAVS DP+AYP PCLYVQ+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

XP_008467269.1 PREDICTED: chloride conductance regulatory protein ICln isoform X2 [Cucumis melo]

2.1e-34

72.45

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y +R  +  GLP FDV+QGEVLMH++PA+ +VFDNR PEFPGTLYVSSRQ+VWLSDA   KG+A+DFLSMSLHAVS DP+AYP PCLYVQ+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

XP_022159658.1 chloride conductance regulatory protein ICln [Momordica charantia]

3.1e-49

98.96

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Query:  MAMGLRTYPDRRRDGLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        MAMGLRTYPDRRRDGLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQ+
Subjt:  MAMGLRTYPDRRRDGLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

XP_038906602.1 chloride conductance regulatory protein ICln [Benincasa hispida]

4.8e-34

72.45

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y +R     GLP FDVNQGEVLMHI+PA+ +VFDNR PEFPGTLY+SSRQ+VWLSD    KG+A+DFLSMSLHAVS DP+AYP PCLYVQ+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KPP2 Uncharacterized protein

8.8e-34

70.41

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Query:  MAMGLRTYPDRRRDGL--PHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y  R  +GL  P FDV+QGEVLMH++PA+ +VFDNR PEFPGTLY+SSRQ+VWLSD I  KG+A+DFLSMSLHAVS DP+AY  PCLYVQ+
Subjt:  MAMGLRTYPDRRRDGL--PHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

A0A1S3CTC6 chloride conductance regulatory protein ICln isoform X1

1.0e-34

72.45

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y +R  +  GLP FDV+QGEVLMH++PA+ +VFDNR PEFPGTLYVSSRQ+VWLSDA   KG+A+DFLSMSLHAVS DP+AYP PCLYVQ+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

A0A1S3CUF8 chloride conductance regulatory protein ICln isoform X2

1.0e-34

72.45

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y +R  +  GLP FDV+QGEVLMH++PA+ +VFDNR PEFPGTLYVSSRQ+VWLSDA   KG+A+DFLSMSLHAVS DP+AYP PCLYVQ+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

A0A5D3DBS0 Chloride conductance regulatory protein ICln isoform X1

1.0e-34

72.45

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M MGLR Y +R  +  GLP FDV+QGEVLMH++PA+ +VFDNR PEFPGTLYVSSRQ+VWLSDA   KG+A+DFLSMSLHAVS DP+AYP PCLYVQ+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

A0A6J1DZF8 chloride conductance regulatory protein ICln

1.5e-49

98.96

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Query:  MAMGLRTYPDRRRDGLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        MAMGLRTYPDRRRDGLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQ+
Subjt:  MAMGLRTYPDRRRDGLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

SwissProt top hits

e value

%identity

Alignment

P54106 Methylosome subunit pICln

2.6e-06

47.06

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Query:  PGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        PGTLY++  +L WL+ +    GF++++ S+SLHA+S+D  AYP   LYV V
Subjt:  PGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

Q04753 Methylosome subunit pICln

2.0e-06

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Query:  GTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        GTLY++  +L WL  +    GF++++ ++SLHAVS+DP+AYP   LYV V
Subjt:  GTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

Q28678 Methylosome subunit pICln

2.0e-06

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Query:  GTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        GTLY++  +L WL  +    GF++++ ++SLHAVS+DP+AYP   LYV V
Subjt:  GTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

Q61189 Methylosome subunit pICln

2.0e-06

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Query:  GTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        GTLY++  +L WL  +    GF++++ ++SLHAVS+DP+AYP   LYV V
Subjt:  GTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

Q9LVA7 Chloride conductance regulatory protein ICln

2.1e-24

52.04

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M  GLR +  R  D  G P  D + GE LMH+  ++A+   NR  E PGTLY++SR+L+WLSD    KG+A+DFLS+SLHAVS+DP+AY  PC+Y Q+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

Arabidopsis top hits

e value

%identity

Alignment

AT5G62290.1 nucleotide-sensitive chloride conductance regulator (ICln) family protein

1.5e-25

52.04

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M  GLR +  R  D  G P  D + GE LMH+  ++A+   NR  E PGTLY++SR+L+WLSD    KG+A+DFLS+SLHAVS+DP+AY  PC+Y Q+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

AT5G62290.2 nucleotide-sensitive chloride conductance regulator (ICln) family protein

1.5e-25

52.04

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Query:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV
        M  GLR +  R  D  G P  D + GE LMH+  ++A+   NR  E PGTLY++SR+L+WLSD    KG+A+DFLS+SLHAVS+DP+AY  PC+Y Q+
Subjt:  MAMGLRTYPDRRRD--GLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

Sequences

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CDS sequence

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ATGGCTATGGGACTAAGGACATACCCGGACAGAAGGCGTGATGGATTACCACATTTCGACGTCAACCAAGGCGAGGTTCTCATGCACATCGTGCCTGCCATCGCCCTCGT
ATTCGATAATCGCCTTCCCGAGTTCCCTGGTACTCTTTACGTCTCCTCTAGGCAACTGGTTTGGTTGAGTGACGCGATTCAGACAAAAGGCTTTGCAATTGATTTCCTAT
CAATGTCATTACATGCAGTTTCAAAAGACCCCGATGCCTATCCTCATCCTTGTTTATATGTCCAGGTA

mRNA sequence

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Protein sequence

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MAMGLRTYPDRRRDGLPHFDVNQGEVLMHIVPAIALVFDNRLPEFPGTLYVSSRQLVWLSDAIQTKGFAIDFLSMSLHAVSKDPDAYPHPCLYVQV

MS017860 (gene) of Bitter gourd (TR) v1 genome