CuGenDBv2

Gene ID	MS019405
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	General transcription and DNA repair factor IIH helicase subunit XPD
Genome location	scaffold28:149057..149198
RNA-Seq Expression	MS019405
Synteny	MS019405
Gene Ontology terms	GO:0000717 - nucleotide-excision repair, DNA duplex unwinding (biological process) GO:0006366 - transcription by RNA polymerase II (biological process) GO:0006979 - response to oxidative stress (biological process) GO:0009408 - response to heat (biological process) GO:0009411 - response to UV (biological process) GO:0033683 - nucleotide-excision repair, DNA incision (biological process) GO:0045951 - positive regulation of mitotic recombination (biological process) GO:0005634 - nucleus (cellular component) GO:0009507 - chloroplast (cellular component) GO:0003678 - DNA helicase activity (molecular function) GO:0003684 - damaged DNA binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0016887 - ATPase activity (molecular function)
InterPro domains	IPR001945 - RAD3/XPD family IPR045028 - Helicase superfamily 1/2, DinG/Rad3-like

Homology

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GenBank top hits

e value

%identity

Alignment

KAF4352190.1 hypothetical protein G4B88_019326 [Cannabis sativa]

2.1e-11

86.96

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHI
        +E MQHKLVFIETQDVVET LALD YRKACDCGRG VFFSVARY I
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHI

KMZ72337.1 putative DNA repair helicase rad3/xp-d [Zostera marina]

6.1e-11

82.98

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        QE MQHKLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

XP_010278066.1 PREDICTED: DNA repair helicase XPD isoform X2 [Nelumbo nucifera]

4.6e-11

86.36

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARY
        Q+ MQHKLVFIETQDVVET LALD YR+ACDCGRG VFFSVARY
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARY

XP_024387541.1 general transcription and DNA repair factor IIH helicase subunit XPD-like [Physcomitrium patens]

6.1e-11

82.98

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        QE MQHKLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

XP_038898339.1 general transcription and DNA repair factor IIH helicase subunit XPD isoform X2 [Benincasa hispida]

1.6e-11

86.67

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYH
        +E MQHKLVFIETQDVVET LALD YRKACDCGRG VFFSVA YH
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYH

TrEMBL top hits

e value

%identity

Alignment

A0A1U8BM38 General transcription and DNA repair factor IIH helicase subunit XPD

2.3e-11

86.36

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARY
        Q+ MQHKLVFIETQDVVET LALD YR+ACDCGRG VFFSVARY
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARY

A0A7I3ZZ66 HELICc2 domain-containing protein

2.9e-11

82.98

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        QE MQHKLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

A0A7I4A080 DNA helicase

2.9e-11

82.98

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        QE MQHKLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

A0A7J6E2Y6 General transcription and DNA repair factor IIH helicase subunit XPD

1.0e-11

86.96

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHI
        +E MQHKLVFIETQDVVET LALD YRKACDCGRG VFFSVARY I
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHI

A9T079 General transcription and DNA repair factor IIH helicase subunit XPD

2.9e-11

82.98

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        QE MQHKLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

SwissProt top hits

e value

%identity

Alignment

A6QLJ0 General transcription and DNA repair factor IIH helicase subunit XPD

2.0e-04

56.41

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Query:  QHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVAR
        ++KL+FIETQD  ET +AL+ Y++AC+ GRG +  SVAR
Subjt:  QHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVAR

P06839 General transcription and DNA repair factor IIH helicase subunit XPD

3.0e-05

57.14

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Query:  ERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVAR
        E  +HKL+ +ET D  ET LAL+ YRKAC  GRG +  SVAR
Subjt:  ERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVAR

Q55G81 General transcription and DNA repair factor IIH helicase subunit XPD

3.0e-05

57.5

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Query:  MQHKLVFIETQDVVETMLAL-DYRKACDCGRGTVFFSVAR
        + +KL+F+ET D  E+ LAL +Y+KACD GRG V  SVAR
Subjt:  MQHKLVFIETQDVVETMLAL-DYRKACDCGRGTVFFSVAR

Q60452 General transcription and DNA repair factor IIH helicase subunit XPD

2.0e-04

56.41

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Query:  QHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVAR
        ++KL+FIETQD  ET +AL+ Y++AC+ GRG +  SVAR
Subjt:  QHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVAR

Q8W4M7 General transcription and DNA repair factor IIH helicase subunit XPD

2.0e-12

78.72

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        +E MQ KLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

Arabidopsis top hits

e value

%identity

Alignment

AT1G03190.1 RAD3-like DNA-binding helicase protein

1.4e-13

78.72

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        +E MQ KLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

AT1G03190.2 RAD3-like DNA-binding helicase protein

1.4e-13

78.72

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Query:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA
        +E MQ KLVFIETQDVVET LALD YR+ACDCGRG VFFSVAR  +A
Subjt:  QERMQHKLVFIETQDVVETMLALD-YRKACDCGRGTVFFSVARYHIA

Sequences

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CDS sequence

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CAGGAAAGAATGCAGCATAAACTTGTGTTTATTGAGACCCAAGATGTGGTGGAGACTATGCTGGCTCTCGACTACCGCAAGGCTTGCGATTGTGGGAGAGGTACTGTGTT
TTTCTCCGTAGCCAGGTATCATATTGCG

mRNA sequence

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CAGGAAAGAATGCAGCATAAACTTGTGTTTATTGAGACCCAAGATGTGGTGGAGACTATGCTGGCTCTCGACTACCGCAAGGCTTGCGATTGTGGGAGAGGTACTGTGTT
TTTCTCCGTAGCCAGGTATCATATTGCG

Protein sequence

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QERMQHKLVFIETQDVVETMLALDYRKACDCGRGTVFFSVARYHIA

MS019405 (gene) of Bitter gourd (TR) v1 genome