CuGenDBv2

Gene ID	MS019639
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	membrane magnesium transporter
Genome location	scaffold729:1205511..1207027
RNA-Seq Expression	MS019639
Synteny	MS019639
Gene Ontology terms	GO:0098655 - cation transmembrane transport (biological process) GO:0005769 - early endosome (cellular component) GO:0005794 - Golgi apparatus (cellular component) GO:0005886 - plasma membrane (cellular component) GO:0072546 - ER membrane protein complex (cellular component) GO:0022890 - inorganic cation transmembrane transporter activity (molecular function)
InterPro domains	IPR018937 - Membrane magnesium transporter

Homology

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GenBank top hits

e value

%identity

Alignment

XP_004137837.1 membrane magnesium transporter [Cucumis sativus]

7.3e-44

87.74

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEFS PP +VA+ELI+GLVLSMWAALTVPGKF SINP++EENRIVSLPAN DFMVFNHRGRLFP Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

XP_008442703.1 PREDICTED: membrane magnesium transporter [Cucumis melo]

1.3e-43

87.74

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEFS PP +VAIELI+GLVLSMWAALTVPGKF SINP++EENRIVSLPAN DFMVFNHRGRLFP + 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

XP_022144662.1 membrane magnesium transporter [Momordica charantia]

3.1e-50

100

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

XP_022955639.1 membrane magnesium transporter [Cucurbita moschata]

5.6e-44

88.68

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEFS PP NVAIEL++GLVLSMWAALTVPGKFLSINP+SEENRIVSLPAN DFMVFNHRG+LF  Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

XP_038903501.1 membrane magnesium transporter [Benincasa hispida]

1.9e-44

88.68

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEFS PP +VAIELI+GLVLSMWAALTVPGKF SINP++EENRIVSLPAN DFM+FNHRGRLFP QT
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LFT4 Uncharacterized protein

3.6e-44

87.74

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEFS PP +VA+ELI+GLVLSMWAALTVPGKF SINP++EENRIVSLPAN DFMVFNHRGRLFP Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

A0A5D3DND5 Membrane magnesium transporter

6.1e-44

87.74

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEFS PP +VAIELI+GLVLSMWAALTVPGKF SINP++EENRIVSLPAN DFMVFNHRGRLFP + 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

A0A6J1CUB1 membrane magnesium transporter

1.5e-50

100

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

A0A6J1GWV2 membrane magnesium transporter

2.7e-44

88.68

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEFS PP NVAIEL++GLVLSMWAALTVPGKFLSINP+SEENRIVSLPAN DFMVFNHRG+LF  Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

A0A6J1L020 membrane magnesium transporter

6.1e-44

87.74

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        MGV FVVGVFGVLILAHAAYSTIQYR+LLKIMQEEF+ PP NVAIEL++GLVLSMWAALTVPGKFLSINP+SEENRIVSLPAN DFMVFNHRG+LF  Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLKLKH
        DLKLKH
Subjt:  DLKLKH

SwissProt top hits

e value

%identity

Alignment

Q05AU4 ER membrane protein complex subunit 5-B

7.5e-07

28.26

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Query:  VVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL
        +VG+ G+  LAHAA+S  Q+R+ +++ ++E    P+++ ++ ++  +++ +  + + G+F  ++  SE       +L  +  F VFNHRGR+
Subjt:  VVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL

Q28HV5 ER membrane protein complex subunit 5

7.5e-07

28.26

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Query:  VVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL
        +VG+ G+  LAHAA+S  Q+R+ +++ ++E    P+++ ++ ++  +++ +  + + G+F  ++  SE       +L  +  F VFNHRGR+
Subjt:  VVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL

Q2HIM5 Membrane magnesium transporter

5.1e-40

77.67

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        M + F+VGVFGVLIL+HAAYSTIQYR LLKIM+EEFS PP+NV +ELIIGL L MWAALT PGKFLSI+PDS+ENR V LP NSDFM+FNHRGRLFP Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLK
        D+K
Subjt:  DLK

Q6GQ49 ER membrane protein complex subunit 5-A

7.5e-07

28.26

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Query:  VVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL
        +VG+ G+  LAHAA+S  Q+R+ +++ ++E    P+++ ++ ++  +++ +  + + G+F  ++  SE       +L  +  F VFNHRGR+
Subjt:  VVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL

Q6TLE4 ER membrane protein complex subunit 5

4.4e-07

29.29

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Query:  MGVSFVVGVFGV--LILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL
        M  SF  GV G+    LAHAA+S  Q+R+ +++ ++E    P+++ ++ ++  V++ +  + + G+F  ++  SE       +L  +  F +FNHRGR+
Subjt:  MGVSFVVGVFGV--LILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSE--ENRIVSLPANSDFMVFNHRGRL

Arabidopsis top hits

e value

%identity

Alignment

AT5G03345.1 FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium transporter (InterPro:IPR018937); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

3.6e-41

77.67

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        M + F+VGVFGVLIL+HAAYSTIQYR LLKIM+EEFS PP+NV +ELIIGL L MWAALT PGKFLSI+PDS+ENR V LP NSDFM+FNHRGRLFP Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLK
        D+K
Subjt:  DLK

AT5G03345.2 FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium transporter (InterPro:IPR018937); Has 155 Blast hits to 155 proteins in 63 species: Archae - 0; Bacteria - 0; Metazoa - 105; Fungi - 0; Plants - 44; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink).

3.4e-39

75.73

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Query:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT
        M + F+VGVFGVLIL+HAAYSTIQ   LLKIM+EEFS PP+NV +ELIIGL L MWAALT PGKFLSI+PDS+ENR V LP NSDFM+FNHRGRLFP Q 
Subjt:  MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQT

Query:  DLK
        D+K
Subjt:  DLK

Sequences

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CDS sequence

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ATGGGAGTGAGCTTCGTTGTTGGCGTCTTCGGAGTTCTAATTCTGGCTCATGCTGCTTATTCTACCATCCAATATAGGAACTTATTGAAGATCATGCAGGAAGAGTTCTC
AGCACCTCCAGTTAATGTGGCAATCGAATTGATCATAGGGTTAGTATTGTCTATGTGGGCTGCGCTCACCGTGCCAGGGAAGTTCCTATCGATTAATCCAGATTCTGAGG
AGAATAGGATAGTTTCTCTTCCCGCCAATTCAGATTTTATGGTCTTCAACCACAGAGGCAGATTATTTCCCCTGCAAACGGATTTGAAGCTGAAACAT

mRNA sequence

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Protein sequence

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MGVSFVVGVFGVLILAHAAYSTIQYRNLLKIMQEEFSAPPVNVAIELIIGLVLSMWAALTVPGKFLSINPDSEENRIVSLPANSDFMVFNHRGRLFPLQTDLKLKH

MS019639 (gene) of Bitter gourd (TR) v1 genome