CuGenDBv2

Gene ID	MS023046
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	Paired amphipathic helix protein Sin3-like 4
Genome location	scaffold502:87792..88187
RNA-Seq Expression	MS023046
Synteny	MS023046
Gene Ontology terms	GO:0000122 - negative regulation of transcription by RNA polymerase II (biological process) GO:0016575 - histone deacetylation (biological process) GO:0000118 - histone deacetylase complex (cellular component) GO:0000785 - chromatin (cellular component) GO:0003714 - transcription corepressor activity (molecular function)
InterPro domains	IPR013194 - Histone deacetylase interacting domain IPR039774 - Transcriptional regulatory protein Sin3-like

Homology

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GenBank top hits

e value

%identity

Alignment

KAG2587450.1 hypothetical protein PVAP13_5NG150362 [Panicum virgatum]

2.7e-48

73.48

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN+A KHVEEL++KM    DN+V  E PIRI++HL+ LNLRCIERLYGDHG+DV+DVLRKN++VALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEW++CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

KAG2587451.1 hypothetical protein PVAP13_5NG150362 [Panicum virgatum]

2.7e-48

73.48

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN+A KHVEEL++KM    DN+V  E PIRI++HL+ LNLRCIERLYGDHG+DV+DVLRKN++VALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEW++CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

XP_022151191.1 paired amphipathic helix protein Sin3-like 4 isoform X1 [Momordica charantia]

1.6e-48

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELLDK+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

XP_022151192.1 paired amphipathic helix protein Sin3-like 4 isoform X2 [Momordica charantia]

1.6e-48

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELLDK+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

XP_022151193.1 paired amphipathic helix protein Sin3-like 4 isoform X3 [Momordica charantia]

1.6e-48

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELLDK+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

TrEMBL top hits

e value

%identity

Alignment

A0A5A7STB7 Paired amphipathic helix protein Sin3-like 4 isoform X1

5.1e-48

73.48

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELL+K+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKN+ +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

A0A5D3CUK2 Paired amphipathic helix protein Sin3-like 4 isoform X2

5.1e-48

73.48

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELL+K+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKN+ +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

A0A6J1DBI6 paired amphipathic helix protein Sin3-like 4 isoform X3

7.8e-49

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELLDK+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

A0A6J1DCT7 paired amphipathic helix protein Sin3-like 4 isoform X2

7.8e-49

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELLDK+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

A0A6J1DDV1 paired amphipathic helix protein Sin3-like 4 isoform X1

7.8e-49

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESVN   K VEELLDK+NN   N + A+CPI IEDHL+ LNLRCIERLYGDHG+DV+DVLRKNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DFN+VWA+I+A NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

SwissProt top hits

e value

%identity

Alignment

O04539 Paired amphipathic helix protein Sin3-like 4

1.1e-44

67.42

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESV SA   VEELL K+N+N+   +  + PI IEDHL+ LNLRCIERLY DHG+DV+D+L+KN+ +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR +FN+VWA I+  NYH
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

O48686 Paired amphipathic helix protein Sin3-like 3

6.4e-48

69.7

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + F HM  K+QYEESLF+CED+RFELDMLLESVNS  KHVEELL K+N+N+   +    PIR+EDHL+ LNLRCIERLYGDHG+DV+DVL+KN ++ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DF++VWA+I+A NY+
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

Q9LFQ3 Paired amphipathic helix protein Sin3-like 2

1.5e-41

64.39

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  ++QYEESLF+CED+RFELDMLLESV SAAK  EELL   N   D  +  E   RIEDH + LNLRCIERLYGDHG+DV D++RKN A ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQ+EW +CR+ FN VWA ++A N++
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

Q9XIE1 Paired amphipathic helix protein Sin3-like 5

2.3e-45

67.42

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESV++A K VE LL+K+NN   N +  E PI I +HLS LNLRCIERLYGD+G+DV+D L+KNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DF +VWA+++A N+H
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

Q9XIK6 Paired amphipathic helix protein Sin3-like 6

1.5e-41

62.88

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + F HM  K+QYEESLF+CED+R+E+DMLL SV+SA K VE LL+KMNN   N +  +  I IE HLS +NLRCIERLYGD+G+DV+D+L+KN   ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+C  DF +VWA+++A N+H
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

Arabidopsis top hits

e value

%identity

Alignment

AT1G24190.1 SIN3-like 3

4.5e-49

69.7

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + F HM  K+QYEESLF+CED+RFELDMLLESVNS  KHVEELL K+N+N+   +    PIR+EDHL+ LNLRCIERLYGDHG+DV+DVL+KN ++ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DF++VWA+I+A NY+
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

AT1G24190.2 SIN3-like 3

4.5e-49

69.7

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + F HM  K+QYEESLF+CED+RFELDMLLESVNS  KHVEELL K+N+N+   +    PIR+EDHL+ LNLRCIERLYGDHG+DV+DVL+KN ++ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DF++VWA+I+A NY+
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

AT1G59890.1 SIN3-like 5

1.6e-46

67.42

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESV++A K VE LL+K+NN   N +  E PI I +HLS LNLRCIERLYGD+G+DV+D L+KNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DF +VWA+++A N+H
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

AT1G59890.2 SIN3-like 5

1.6e-46

67.42

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESV++A K VE LL+K+NN   N +  E PI I +HLS LNLRCIERLYGD+G+DV+D L+KNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DF +VWA+++A N+H
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

AT1G59890.3 SIN3-like 5

1.6e-46

67.42

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Query:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV
        + FKHM  K+QYEESLF+CED+RFELDMLLESV++A K VE LL+K+NN   N +  E PI I +HLS LNLRCIERLYGD+G+DV+D L+KNS +ALPV
Subjt:  FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPV

Query:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH
        IL RLKQKQEEWA+CR DF +VWA+++A N+H
Subjt:  ILARLKQKQEEWAQCRDDFNQVWAQIHADNYH

Sequences

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CDS sequence

Show/hide CDS sequence

TTCAAATTCAAACACATGATGCCCAAATCCCAGTACGAGGAGAGCCTGTTCCAATGTGAGGATGAGAGATTCGAACTCGACATGCTGCTGGAGTCTGTCAACTCCGCTGC
CAAGCATGTCGAGGAACTGCTCGACAAGATGAACAACAACGACGACAATGCGGTTGGAGCGGAATGTCCGATCAGGATTGAGGATCACCTCAGTGTTCTGAATCTGAGGT
GCATCGAACGGCTGTATGGTGATCATGGGGTTGATGTTGTGGATGTGTTGAGGAAGAATTCGGCTGTGGCTCTGCCTGTTATTTTGGCCCGTTTGAAGCAGAAACAGGAA
GAATGGGCACAGTGTCGTGATGATTTCAATCAAGTTTGGGCTCAAATACACGCTGACAACTATCAT

mRNA sequence

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Protein sequence

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FKFKHMMPKSQYEESLFQCEDERFELDMLLESVNSAAKHVEELLDKMNNNDDNAVGAECPIRIEDHLSVLNLRCIERLYGDHGVDVVDVLRKNSAVALPVILARLKQKQE
EWAQCRDDFNQVWAQIHADNYH

MS023046 (gene) of Bitter gourd (TR) v1 genome