CuGenDBv2

Gene ID	Moc06g37740
Organism	Momordica charantia cv. OHB3-1 (Bitter gourd (OHB3-1) v2)
Description	RNase H domain-containing protein
Genome location	chr6:29026988..29027952
RNA-Seq Expression	Moc06g37740
Synteny	Moc06g37740
Gene Ontology terms	GO:0090502 - RNA phosphodiester bond hydrolysis, endonucleolytic (biological process) GO:0003676 - nucleic acid binding (molecular function) GO:0004523 - RNA-DNA hybrid ribonuclease activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

XP_022143535.1 uncharacterized protein LOC111013412 [Momordica charantia]

9.6e-53

87.18

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Query:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN
        +DK GEEER+RSMIIAWQIWEMRNKSIFKGVH ETRDIQLAIDRYIIN A RN NL+GKSTNKDLHL RRI DNTGA+WKPPTS SWKLNT++AWRADTN
Subjt:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN

Query:  TGGIGWILRDEKGEVIR
        TGGIGWILRDEKGEVI+
Subjt:  TGGIGWILRDEKGEVIR

XP_022154990.1 uncharacterized protein LOC111022134 isoform X1 [Momordica charantia]

6.8e-75

84.76

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Query:  KKEETTQHILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRN
        KKEETTQHILWECKVIKDIWINCTPIE+ FFYID TNWTTKEY EWL+DK GEEER+RSMIIA QIWEMRNKSIFKGVHSETRDIQLAIDRYIIN A ++
Subjt:  KKEETTQHILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRN

Query:  INLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR
         NL+ KS  KD H  RRIGDNT ARWKPPTS SWKLNTD+AWRADTNT GIGWILRDEKGEVI+
Subjt:  INLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR

XP_022154991.1 uncharacterized protein LOC111022134 isoform X2 [Momordica charantia]

3.9e-54

77.62

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Query:  NCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDN
        NC   E +F     TNWTTKEY EWL+DK GEEER+RSMIIA QIWEMRNKSIFKGVHSETRDIQLAIDRYIIN A ++ NL+ KS  KD H  RRIGDN
Subjt:  NCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDN

Query:  TGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR
        T ARWKPPTS SWKLNTD+AWRADTNT GIGWILRDEKGEVI+
Subjt:  TGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR

XP_022156777.1 uncharacterized protein LOC111023608 [Momordica charantia]

5.1e-54

86.55

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Query:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN
        +DK GEEER+RSMIIAWQIWEMRNKSIFKGVHSETRDIQL IDRYIIN A R+ NL+GKS NKDLHL RRIGDNTGARWKPPTS SWKLNTD+AWRADTN
Subjt:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN

Query:  TGGIGWILRDEKGEVIRVE
        TGGIGWILRDEKGEVI+ +
Subjt:  TGGIGWILRDEKGEVIRVE

XP_024042628.1 uncharacterized protein LOC112099434 [Citrus clementina]

2.2e-20

26.97

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Query:  PVYVQDGMKHNSVVCLMSERGRWNENLVRDNFYEEETEMILKIPLPRQSQKDEIIWNKDKRGLLTVKSAYHLGMKLEQAKECSTSNGENQKLWKKEETTQ
        P+ V+      +V  L++   RW E L+ D F +E+ + I+ IPLPR   +D++IW+ D++G  +VKS Y + +K++     S+S   N     + E   
Subjt:  PVYVQDGMKHNSVVCLMSERGRWNENLVRDNFYEEETEMILKIPLPRQSQKDEIIWNKDKRGLLTVKSAYHLGMKLEQAKECSTSNGENQKLWKKEETTQ

Query:  HILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFK----GVHSETRDIQLAIDRY-------IING
        H L ECK  +  W +    ES   + D          + L+ K+ + + +   +  W IW  RNK IF+    G        +  ++ Y       +I G
Subjt:  HILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFK----GVHSETRDIQLAIDRY-------IING

Query:  ADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVI
        AD+                      T   W PP    +K+N D+A R + N  G+G ++RD  G +I
Subjt:  ADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVI

TrEMBL top hits

e value

%identity

Alignment

A0A2N9IYH1 RNase H domain-containing protein

5.2e-20

26.44

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Query:  ERGRWNENLVRDNFYEEETEMILKIPLPRQSQKDEIIWNKDKRGLLTVKSAYHLGMKLEQAKECSTSNGENQKLWK------------------KEETTQ
        E+GRWN  L+   F   + E+I +IPL  +  +D++IW  ++RG+ +VKSAY L ++       S+  G   K W                   + ET  
Subjt:  ERGRWNENLVRDNFYEEETEMILKIPLPRQSQKDEIIWNKDKRGLLTVKSAYHLGMKLEQAKECSTSNGENQKLWK------------------KEETTQ

Query:  HILWECKVIKDIWINCT-PIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDI----QLAIDRYIINGADRNIN
        HILW C   + +W  C+ PI          N +  ++LE  +  +G  E +  + +AW +W  RN+ +++G+HS   D+     +   +++  G    ++
Subjt:  HILWECKVIKDIWINCT-PIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDI----QLAIDRYIINGADRNIN

Query:  LEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVI
         E     +               W PP   S+KL+    +R D+   G+G +LRD +G V+
Subjt:  LEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVI

A0A6J1CP26 uncharacterized protein LOC111013412

4.6e-53

87.18

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Query:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN
        +DK GEEER+RSMIIAWQIWEMRNKSIFKGVH ETRDIQLAIDRYIIN A RN NL+GKSTNKDLHL RRI DNTGA+WKPPTS SWKLNT++AWRADTN
Subjt:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN

Query:  TGGIGWILRDEKGEVIR
        TGGIGWILRDEKGEVI+
Subjt:  TGGIGWILRDEKGEVIR

A0A6J1DL64 uncharacterized protein LOC111022134 isoform X1

3.3e-75

84.76

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Query:  KKEETTQHILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRN
        KKEETTQHILWECKVIKDIWINCTPIE+ FFYID TNWTTKEY EWL+DK GEEER+RSMIIA QIWEMRNKSIFKGVHSETRDIQLAIDRYIIN A ++
Subjt:  KKEETTQHILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRN

Query:  INLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR
         NL+ KS  KD H  RRIGDNT ARWKPPTS SWKLNTD+AWRADTNT GIGWILRDEKGEVI+
Subjt:  INLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR

A0A6J1DQC9 uncharacterized protein LOC111022134 isoform X2

1.9e-54

77.62

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Query:  NCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDN
        NC   E +F     TNWTTKEY EWL+DK GEEER+RSMIIA QIWEMRNKSIFKGVHSETRDIQLAIDRYIIN A ++ NL+ KS  KD H  RRIGDN
Subjt:  NCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDN

Query:  TGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR
        T ARWKPPTS SWKLNTD+AWRADTNT GIGWILRDEKGEVI+
Subjt:  TGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIR

A0A6J1DSV1 uncharacterized protein LOC111023608

2.5e-54

86.55

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Query:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN
        +DK GEEER+RSMIIAWQIWEMRNKSIFKGVHSETRDIQL IDRYIIN A R+ NL+GKS NKDLHL RRIGDNTGARWKPPTS SWKLNTD+AWRADTN
Subjt:  IDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTN

Query:  TGGIGWILRDEKGEVIRVE
        TGGIGWILRDEKGEVI+ +
Subjt:  TGGIGWILRDEKGEVIRVE

SwissProt top hits	e value	%identity	Alignment
No hits found

Arabidopsis top hits

e value

%identity

Alignment

AT2G34320.1 Polynucleotidyl transferase, ribonuclease H-like superfamily protein

5.7e-11

28.99

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Query:  ETTQHILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEY--------LEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIIN
        ET  H+L++C   + +W   +PI +         WT   Y        LE  I K+G+       ++ W++W+ RN+ +FKG   +  ++          
Subjt:  ETTQHILWECKVIKDIWINCTPIESKFFYIDTTNWTTKEY--------LEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIIN

Query:  GADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSW-KLNTDSAWRADTNTGGIGWILRDEKGEVI
         + R   LEGK++        ++  N   +WK P  Y W K NTD+ W+ +    GIGWILR+E G V+
Subjt:  GADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSW-KLNTDSAWRADTNTGGIGWILRDEKGEVI

AT4G29090.1 Ribonuclease H-like superfamily protein

3.5e-13

24.14

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Query:  LMSERGR-WNENLVRDNFYEEETEMILKIPLPRQSQKDEIIWNKDKRGLLTVKSAY----HLGMKLEQAKECS--TSNGENQKLWKKEET--TQHILWEC
        L+ E GR W ++++   F E E ++I ++    +   D   W+    G  TVKS Y     +  K    +E S  + N   QK+WK + +   QH LW+C
Subjt:  LMSERGR-WNENLVRDNFYEEETEMILKIPLPRQSQKDEIIWNKDKRGLLTVKSAY----HLGMKLEQAKECS--TSNGENQKLWKKEET--TQHILWEC

Query:  -----------------------------KVIKDIWINCTPIESKFFYIDTT-----NWTTKEY--LEWL--IDKVGEEERKRSMII---AWQIWEMRNK
                                     + +  +   CT     +            W    Y  L W+  +     +  K S ++    W++W+ RN+
Subjt:  -----------------------------KVIKDIWINCTPIESKFFYIDTT-----NWTTKEY--LEWL--IDKVGEEERKRSMII---AWQIWEMRNK

Query:  SIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEV
         +F+G     +++   + R   +  +  I  E +S      + R    ++  RW+PP     K NTD+ W  D    GIGW+LR+EKGEV
Subjt:  SIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARWKPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEV

Sequences

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CDS sequence

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ATGCCAGTTTATGTCCAAGATGGGATGAAACACAATTCTGTGGTATGTCTAATGAGTGAAAGGGGAAGGTGGAATGAAAATCTTGTTCGTGATAACTTTTATGAGGAGGA
AACTGAAATGATTCTTAAAATTCCTTTACCGCGACAGAGTCAAAAAGATGAAATTATATGGAATAAAGACAAAAGAGGGTTGTTAACTGTTAAAAGCGCCTATCACTTAG
GGATGAAATTGGAGCAAGCAAAAGAATGTTCTACCTCTAATGGTGAAAATCAAAAGCTGTGGAAAAAAGAAGAAACTACTCAACATATCCTATGGGAATGTAAGGTAATT
AAAGATATATGGATAAATTGTACCCCTATTGAATCCAAATTTTTCTATATTGACACGACAAACTGGACCACAAAAGAGTATTTGGAGTGGCTAATTGATAAGGTTGGTGA
AGAAGAACGTAAAAGAAGCATGATCATAGCTTGGCAGATTTGGGAAATGAGGAACAAATCAATTTTCAAAGGTGTTCATTCAGAAACTAGAGACATTCAATTGGCGATTG
ACAGATACATAATCAACGGTGCAGATCGAAATATAAATCTAGAAGGAAAGTCAACAAACAAGGACTTGCACCTGACAAGGCGAATTGGAGACAATACAGGAGCCCGATGG
AAACCTCCCACATCATATTCATGGAAGTTAAATACGGATTCAGCATGGCGAGCTGATACAAACACTGGGGGGATTGGTTGGATTTTAAGAGACGAGAAGGGAGAAGTCAT
CAGAGTAGAATTATAA

mRNA sequence

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Protein sequence

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MPVYVQDGMKHNSVVCLMSERGRWNENLVRDNFYEEETEMILKIPLPRQSQKDEIIWNKDKRGLLTVKSAYHLGMKLEQAKECSTSNGENQKLWKKEETTQHILWECKVI
KDIWINCTPIESKFFYIDTTNWTTKEYLEWLIDKVGEEERKRSMIIAWQIWEMRNKSIFKGVHSETRDIQLAIDRYIINGADRNINLEGKSTNKDLHLTRRIGDNTGARW
KPPTSYSWKLNTDSAWRADTNTGGIGWILRDEKGEVIRVEL

Moc06g37740 (gene) of Bitter gourd (OHB3-1) v2 genome