CuGenDBv2

Gene ID	Moc09g03380
Organism	Momordica charantia cv. OHB3-1 (Bitter gourd (OHB3-1) v2)
Description	regulator of telomere elongation helicase 1 homolog isoform X1
Genome location	chr9:2617359..2619491
RNA-Seq Expression	Moc09g03380
Synteny	Moc09g03380
Gene Ontology terms	GO:0009555 - pollen development (biological process) GO:0010569 - regulation of double-strand break repair via homologous recombination (biological process) GO:0032508 - DNA duplex unwinding (biological process) GO:0036297 - interstrand cross-link repair (biological process) GO:0043007 - maintenance of rDNA (biological process) GO:0045910 - negative regulation of DNA recombination (biological process) GO:0048364 - root development (biological process) GO:0070716 - mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication (biological process) GO:0090657 - telomeric loop disassembly (biological process) GO:1904430 - negative regulation of t-circle formation (biological process) GO:0005634 - nucleus (cellular component) GO:0003677 - DNA binding (molecular function) GO:0003678 - DNA helicase activity (molecular function) GO:0005524 - ATP binding (molecular function) GO:0016887 - ATPase activity (molecular function) GO:0070182 - DNA polymerase binding (molecular function)
InterPro domains	NA

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022148878.1 regulator of telomere elongation helicase 1 homolog [Momordica charantia]

1.4e-101

100

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Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

XP_022992069.1 regulator of telomere elongation helicase 1 homolog isoform X1 [Cucurbita maxima]

9.7e-71

74.87

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Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        +N+Q +K+LLVGC  +KRKL STE A A+ M+ S GPSGA+PSE  N+ FKICSVKSE S SD+RG+QND V   LL  H +SHTT+KMG ES N+NDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P + GDEEAKGSDFLSQVR+KLSAREYK+FVGFMKALKTKAM ISQVLQSI+GIFSGPDRL LR GFKDYIPAKYHSLYEQFLGT T
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

XP_022992070.1 regulator of telomere elongation helicase 1 isoform X2 [Cucurbita maxima]

9.7e-71

74.87

Show/hide

Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        +N+Q +K+LLVGC  +KRKL STE A A+ M+ S GPSGA+PSE  N+ FKICSVKSE S SD+RG+QND V   LL  H +SHTT+KMG ES N+NDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P + GDEEAKGSDFLSQVR+KLSAREYK+FVGFMKALKTKAM ISQVLQSI+GIFSGPDRL LR GFKDYIPAKYHSLYEQFLGT T
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

XP_038900179.1 regulator of telomere elongation helicase 1 homolog isoform X1 [Benincasa hispida]

2.2e-70

75.92

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Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        M+EQ NK LLVGC  +KRKL STEH PA+ MR S GPSGA+PSE + + FKICSVKSEASPSDSR +QND V   LL    + HT +KMG ESV QNDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P H GDEEAKGSDFLSQVREKL+AREY++FVGFMKALKTKAM ISQVLQSI+ IFSGPDRL LR GFKDYIPAKYH LYEQFLGTST
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

XP_038900181.1 regulator of telomere elongation helicase 1 homolog isoform X2 [Benincasa hispida]

2.2e-70

75.92

Show/hide

Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        M+EQ NK LLVGC  +KRKL STEH PA+ MR S GPSGA+PSE + + FKICSVKSEASPSDSR +QND V   LL    + HT +KMG ESV QNDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P H GDEEAKGSDFLSQVREKL+AREY++FVGFMKALKTKAM ISQVLQSI+ IFSGPDRL LR GFKDYIPAKYH LYEQFLGTST
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

TrEMBL top hits

e value

%identity

Alignment

A0A6J1D6Q1 DNA helicase

6.7e-102

100

Show/hide

Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

A0A6J1GQH0 regulator of telomere elongation helicase 1 homolog isoform X1

2.6e-69

74.87

Show/hide

Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        +N+Q +K+LLV    +KRKL STE A A+ M+ S GPSGA+PSE  N+ FKICSVKSE S SD+RG+QND V   LL  H +SHTT+KMG ES N+NDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P H GDEEAKGSDFLSQVR+KLSAREYK+FVGFMKALKTKAM ISQVLQSI+GIFSGPDRL LR GFKDYIPAKYHSLYEQFLGTST
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

A0A6J1GQI2 regulator of telomere elongation helicase 1 isoform X2

2.6e-69

74.87

Show/hide

Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        +N+Q +K+LLV    +KRKL STE A A+ M+ S GPSGA+PSE  N+ FKICSVKSE S SD+RG+QND V   LL  H +SHTT+KMG ES N+NDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P H GDEEAKGSDFLSQVR+KLSAREYK+FVGFMKALKTKAM ISQVLQSI+GIFSGPDRL LR GFKDYIPAKYHSLYEQFLGTST
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

A0A6J1JUP3 regulator of telomere elongation helicase 1 isoform X2

4.7e-71

74.87

Show/hide

Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        +N+Q +K+LLVGC  +KRKL STE A A+ M+ S GPSGA+PSE  N+ FKICSVKSE S SD+RG+QND V   LL  H +SHTT+KMG ES N+NDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P + GDEEAKGSDFLSQVR+KLSAREYK+FVGFMKALKTKAM ISQVLQSI+GIFSGPDRL LR GFKDYIPAKYHSLYEQFLGT T
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

A0A6J1JWK2 regulator of telomere elongation helicase 1 homolog isoform X1

4.7e-71

74.87

Show/hide

Query:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI
        +N+Q +K+LLVGC  +KRKL STE A A+ M+ S GPSGA+PSE  N+ FKICSVKSE S SD+RG+QND V   LL  H +SHTT+KMG ES N+NDKI
Subjt:  MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKI

Query:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        IKC P + GDEEAKGSDFLSQVR+KLSAREYK+FVGFMKALKTKAM ISQVLQSI+GIFSGPDRL LR GFKDYIPAKYHSLYEQFLGT T
Subjt:  IKCNPAHLGDEEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

SwissProt top hits

e value

%identity

Alignment

A0A0P0V4R0 Regulator of telomere elongation helicase 1 homolog

5.6e-13

35.44

Show/hide

Query:  STGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKIIKCNPAHLGDEEAKGSDFLSQVREKLSAREYKD
        S GP  AK    S     +C    + SP     +++ A+   L     S+ ++KK  +     N   I  +    G E   G  FL   REKLS  EY+D
Subjt:  STGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKIIKCNPAHLGDEEAKGSDFLSQVREKLSAREYKD

Query:  FVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST
        FV +MKALK K M I   L +I  +FS P+RL L +GF+ ++P  + SLYEQ + + T
Subjt:  FVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

F4HQE2 Regulator of telomere elongation helicase 1 homolog

1.7e-17

51.9

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Query:  EEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGT
        +EA  S FLSQV+EKL+  EYK F+G+M+ALK K +K++ V+QSI+ +F G +R HL  GFKD++P KY   YE+ + T
Subjt:  EEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGT

Arabidopsis top hits

e value

%identity

Alignment

AT1G79950.1 RAD3-like DNA-binding helicase protein

1.2e-18

51.9

Show/hide

Query:  EEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGT
        +EA  S FLSQV+EKL+  EYK F+G+M+ALK K +K++ V+QSI+ +F G +R HL  GFKD++P KY   YE+ + T
Subjt:  EEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGT

Sequences

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CDS sequence

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ATGAATGAACAAGCAAACAAAAAATTGTTGGTAGGGTGTGGTGAAAAGAAGCGGAAATTACTCAGCACAGAGCATGCTCCTGCAGAAACGATGAGGATTTCTACTGGGCC
TTCTGGTGCTAAACCATCTGAACCAAGTAACATTTCCTTCAAAATTTGTTCTGTGAAGTCTGAAGCTTCACCATCTGATAGCAGAGGCATGCAAAATGATGCTGTTGGTC
CAGCATTGCTACACGTACACGGTAGTAGTCATACTACGAAGAAGATGGGTGTAGAGTCTGTCAATCAGAATGACAAGATAATCAAATGCAATCCTGCTCATCTTGGTGAT
GAGGAAGCTAAAGGATCTGATTTTCTGAGTCAGGTCAGAGAGAAACTCAGTGCCAGAGAATACAAGGACTTTGTTGGGTTTATGAAAGCACTTAAAACCAAAGCAATGAA
AATAAGCCAAGTTTTGCAGTCCATTATAGGAATATTTTCAGGACCGGATAGGCTACATCTTCGTAAAGGCTTCAAGGATTATATCCCTGCAAAATATCATTCCTTGTACG
AGCAGTTTCTTGGGACCAGCACGTGA

mRNA sequence

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Protein sequence

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MNEQANKKLLVGCGEKKRKLLSTEHAPAETMRISTGPSGAKPSEPSNISFKICSVKSEASPSDSRGMQNDAVGPALLHVHGSSHTTKKMGVESVNQNDKIIKCNPAHLGD
EEAKGSDFLSQVREKLSAREYKDFVGFMKALKTKAMKISQVLQSIIGIFSGPDRLHLRKGFKDYIPAKYHSLYEQFLGTST

Moc09g03380 (gene) of Bitter gourd (OHB3-1) v2 genome