CuGenDBv2

Gene ID	PI0000374
Organism	Cucumis metuliferus PI 482460 (Melon (PI 482460) v1)
Description	Kinetochore protein NDC80-like protein
Genome location	chr06:8761786..8762910
RNA-Seq Expression	PI0000374
Synteny	PI0000374
Gene Ontology terms	GO:0051301 - cell division (biological process) GO:0051315 - attachment of mitotic spindle microtubules to kinetochore (biological process) GO:0031262 - Ndc80 complex (cellular component)
InterPro domains	IPR005550 - Kinetochore protein Ndc80 IPR038273 - Ndc80 domain superfamily

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6576966.1 Kinetochore protein NDC80-like protein, partial [Cucurbita argyrosperma subsp. sororia]

3.7e-75

74.63

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Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKG GRR PK SFNPPPPPTPQFRRDSD SFASSRPSSIGM+RP AASIDMYKERAVQIS VNTINSSLK+LF+HSFN+TFKPFSPPSLKDLTETI+LLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDY PTKLEDDLPI+LKSLGYPFKINK ILK PPAPHQ Y ILALLHWLVQ                   ++ +  LNSY+ Y+RGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

XP_004149971.2 kinetochore protein NDC80 homolog isoform X1 [Cucumis sativus]

9.8e-84

81.95

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Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKGT RRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRP +ASIDMYKERAVQISTVNTINSSLK+LFSHSFNVTFKPFSPPSLKDLTETINLLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQ YQILALLHWLVQ                   ++ +  LNSYLHYMRGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

XP_008439248.1 PREDICTED: kinetochore protein NDC80 homolog [Cucumis melo]

1.2e-84

82.44

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Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPP+ASIDMYKERAVQISTVNTINSSLK+LFSHSFNVTFKPFSPPSLKDLTETINLLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDYPPTKLEDDLPILLKSLGYPFKINKNILK PPAPHQ YQILALLHWLVQ                   ++ +  LNSYLHYMRGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

XP_022984383.1 kinetochore protein NDC80 homolog [Cucurbita maxima]

3.7e-75

74.63

Show/hide

Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKG GRR PK SFNPPPPPTPQFRRDSD SFASSRPSSIGM+RP AASIDMYKERAVQIS VNTINSSLK+LF+HSFN+TFKPFSPPSLKDLTETI+LLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDY PTKLEDDLPI+LKSLGYPFKINK ILK PPAPHQ Y ILALLHWLVQ                   ++ +  LNSY+ Y+RGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

XP_023553517.1 kinetochore protein NDC80 homolog [Cucurbita pepo subsp. pepo]

3.7e-75

74.63

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Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKG GRR PK SFNPPPPPTPQFRRDSD SFASSRPSSIGM+RP AASIDMYKERAVQIS VNTINSSLK+LF+HSFN+TFKPFSPPSLKDLTETI+LLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDY PTKLEDDLPI+LKSLGYPFKINK ILK PPAPHQ Y ILALLHWLVQ                   ++ +  LNSY+ Y+RGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L740 Uncharacterized protein

4.7e-84

81.95

Show/hide

Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKGT RRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRP +ASIDMYKERAVQISTVNTINSSLK+LFSHSFNVTFKPFSPPSLKDLTETINLLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQ YQILALLHWLVQ                   ++ +  LNSYLHYMRGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

A0A1S3AYB0 kinetochore protein NDC80 homolog

5.6e-85

82.44

Show/hide

Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPP+ASIDMYKERAVQISTVNTINSSLK+LFSHSFNVTFKPFSPPSLKDLTETINLLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDYPPTKLEDDLPILLKSLGYPFKINKNILK PPAPHQ YQILALLHWLVQ                   ++ +  LNSYLHYMRGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

A0A5D3DHD6 Kinetochore protein NDC80-like protein

5.6e-85

82.44

Show/hide

Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPP+ASIDMYKERAVQISTVNTINSSLK+LFSHSFNVTFKPFSPPSLKDLTETINLLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDYPPTKLEDDLPILLKSLGYPFKINKNILK PPAPHQ YQILALLHWLVQ                   ++ +  LNSYLHYMRGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

A0A6J1E5Y9 kinetochore protein NDC80 homolog

1.8e-75

74.63

Show/hide

Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKG GRR PK SFNPPPPPTPQFRRDSD SFASSRPSSIGM+RP AASIDMYKERAVQIS VNTINSSLK+LF+HSFN+TFKPFSPPSLKDLTETI+LLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDY PTKLEDDLPI+LKSLGYPFKINK ILK PPAPHQ Y ILALLHWLVQ                   ++ +  LNSY+ Y+RGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

A0A6J1JAC2 kinetochore protein NDC80 homolog

1.8e-75

74.63

Show/hide

Query:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL
        MKG GRR PK SFNPPPPPTPQFRRDSD SFASSRPSSIGM+RP AASIDMYKERAVQIS VNTINSSLK+LF+HSFN+TFKPFSPPSLKDLTETI+LLL
Subjt:  MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLL

Query:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF
        QCLDY PTKLEDDLPI+LKSLGYPFKINK ILK PPAPHQ Y ILALLHWLVQ                   ++ +  LNSY+ Y+RGDDDSVE L  EF
Subjt:  QCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSVEVL--EF

Query:  TIKIK
          ++K
Subjt:  TIKIK

SwissProt top hits

e value

%identity

Alignment

O14777 Kinetochore protein NDC80 homolog

5.9e-07

33.33

Show/hide

Query:  HSFNVTFKPFSPPSLKDLTETINLLLQCL----DYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL
        ++ NV+ K    PS+KD  +    L   L    + P TK E+++P + K LGYPF ++K+ +    APH    I+A L WL+  +++
Subjt:  HSFNVTFKPFSPPSLKDLTETINLLLQCL----DYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL

Q4R630 Kinetochore protein NDC80 homolog

5.9e-07

33.33

Show/hide

Query:  HSFNVTFKPFSPPSLKDLTETINLLLQCL----DYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL
        ++ NV+ K    PS+KD  +    L   L    + P TK E+++P + K LGYPF ++K+ +    APH    I+A L WL+  +++
Subjt:  HSFNVTFKPFSPPSLKDLTETINLLLQCL----DYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL

Q5U4X5 Kinetochore protein NDC80 homolog

5.0e-06

34.48

Show/hide

Query:  HSFNVTFKPFSPPSLKDLTETINLLLQ--CLDY--PPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL
        +S  +T K    PS KD  +    +    C +Y  P +K E+++P + K LGYPF ++K+ +    APH   QI+A L WL+  ++L
Subjt:  HSFNVTFKPFSPPSLKDLTETINLLLQ--CLDY--PPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL

Q76I89 Kinetochore protein NDC80 homolog

5.9e-07

35.63

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Query:  HSFNVTFKPFSPPSLKD----LTETINLLLQCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL
        ++ NVT K    PS+KD     T     L    + P +K E+++P + K LGYPF ++K+ +    APH   QI+A L WL    +L
Subjt:  HSFNVTFKPFSPPSLKD----LTETINLLLQCLDYPPTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQL

Q9M1G5 Kinetochore protein NDC80 homolog

7.2e-21

35.29

Show/hide

Query:  GRRRPKASFN---PPPPPTPQFR------RDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTET
        G+RR    F    PPPPP+ + +      RDSD SFASSRPSSIG+    A+      +R+  I  +N        L +H+F ++ +    PS+KD++ET
Subjt:  GRRRPKASFN---PPPPPTPQFR------RDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTET

Query:  INLLLQCLDYP--PTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSV
        +  LL  LDYP    K ++DL   LKS   PFKI K+ LK P  PH    +LA++HWL +                   ++    + S+ H++RG+DD V
Subjt:  INLLLQCLDYP--PTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSV

Query:  EVLE
          L+
Subjt:  EVLE

Arabidopsis top hits

e value

%identity

Alignment

AT3G54630.1 CONTAINS InterPro DOMAIN/s: Kinetochore protein Ndc80 (InterPro:IPR005550); Has 24780 Blast hits to 15608 proteins in 1321 species: Archae - 545; Bacteria - 2969; Metazoa - 12597; Fungi - 2181; Plants - 1581; Viruses - 39; Other Eukaryotes - 4868 (source: NCBI BLink).

5.1e-22

35.29

Show/hide

Query:  GRRRPKASFN---PPPPPTPQFR------RDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTET
        G+RR    F    PPPPP+ + +      RDSD SFASSRPSSIG+    A+      +R+  I  +N        L +H+F ++ +    PS+KD++ET
Subjt:  GRRRPKASFN---PPPPPTPQFR------RDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTET

Query:  INLLLQCLDYP--PTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSV
        +  LL  LDYP    K ++DL   LKS   PFKI K+ LK P  PH    +LA++HWL +                   ++    + S+ H++RG+DD V
Subjt:  INLLLQCLDYP--PTKLEDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQ-------------------NLQLSFLNSYLHYMRGDDDSV

Query:  EVLE
          L+
Subjt:  EVLE

Sequences

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CDS sequence

Show/hide CDS sequence

ATGAAGGGAACTGGCCGCCGCCGTCCAAAGGCGTCTTTCAATCCTCCCCCACCCCCTACTCCCCAATTCCGCCGCGATTCCGATGTCAGCTTTGCCAGCAGCCGCCCTTC
TTCCATCGGAATGTCTCGTCCCCCCGCCGCCTCCATCGACATGTACAAAGAACGAGCCGTTCAAATTTCCACTGTCAACACCATCAATTCCTCTCTCAAGGACCTCTTTT
CTCACTCCTTTAACGTAACATTCAAACCCTTCTCTCCCCCTTCCCTCAAAGATCTCACTGAAACTATTAATTTGCTTCTTCAATGTCTCGATTATCCTCCCACTAAACTT
GAGGATGATCTCCCCATCCTTCTCAAATCCCTTGGGTATCCCTTCAAAATTAATAAGAACATCCTCAAGAACCCCCCTGCTCCTCATCAGCGGTACCAAATTCTTGCCCT
ACTTCACTGGCTTGTTCAGAATTTACAATTAAGTTTCTTGAATAGCTATTTGCATTATATGCGTGGGGATGATGATTCGGTGGAGGTTTTAGAATTTACAATTAAGATTA
AAGCTCGATAA

mRNA sequence

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Protein sequence

Show/hide protein sequence

MKGTGRRRPKASFNPPPPPTPQFRRDSDVSFASSRPSSIGMSRPPAASIDMYKERAVQISTVNTINSSLKDLFSHSFNVTFKPFSPPSLKDLTETINLLLQCLDYPPTKL
EDDLPILLKSLGYPFKINKNILKNPPAPHQRYQILALLHWLVQNLQLSFLNSYLHYMRGDDDSVEVLEFTIKIKAR

PI0000374 (gene) of Melon (PI 482460) v1 genome