CuGenDBv2

Gene ID	PI0002743
Organism	Cucumis metuliferus PI 482460 (Melon (PI 482460) v1)
Description	Cysteine synthase
Genome location	chr03:25013965..25014602
RNA-Seq Expression	PI0002743
Synteny	PI0002743
Gene Ontology terms	GO:0006535 - cysteine biosynthetic process from serine (biological process) GO:0019499 - cyanide metabolic process (biological process) GO:0005739 - mitochondrion (cellular component) GO:0004124 - cysteine synthase activity (molecular function) GO:0050017 - L-3-cyanoalanine synthase activity (molecular function)
InterPro domains	IPR001926 - Pyridoxal-phosphate dependent enzyme IPR031111 - L-3-cyanoalanine synthase, mitochondrial IPR036052 - Tryptophan synthase beta subunit-like PLP-dependent enzyme

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAB1214349.1 L-3-cyanoalanine synthase 1, mitochondrial [Morella rubra]

4.7e-43

98.88

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPAN+QVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

KAE7999480.1 hypothetical protein FH972_003904 [Carpinus fangiana]

8.0e-43

97.75

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

XP_019176247.1 PREDICTED: bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [Ipomoea nil]

8.9e-42

94.38

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPANTQ+HFETTGPEIWEDT+G VDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEP ESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

XP_022157695.1 bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [Momordica charantia]

2.3e-42

96.63

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKS+NPNVKIYGVEPAESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

XP_038875773.1 bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [Benincasa hispida]

2.3e-42

96.63

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKS+NPNVKIYGVEPAESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

TrEMBL top hits

e value

%identity

Alignment

A0A2N9EZQ6 Cysteine synthase

4.3e-42

96.63

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPN FMLQQFSNPANT+VHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

A0A371FQE6 Cysteine synthase

4.3e-42

95.51

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPN FMLQQFSNPANTQVHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEP+ESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

A0A5N6QMV3 Cysteine synthase

3.9e-43

97.75

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

A0A6A1VN75 Cysteine synthase

2.3e-43

98.88

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPAN+QVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

A0A6J1DTT8 Cysteine synthase

1.1e-42

96.63

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKS+NPNVKIYGVEPAESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

SwissProt top hits

e value

%identity

Alignment

Q1KLZ1 L-3-cyanoalanine synthase 2, mitochondrial

1.3e-43

93.26

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPN FMLQQFSNPANT+VHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKS+NPNV+IYGVEPAESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

Q1KLZ2 L-3-cyanoalanine synthase 1, mitochondrial

2.9e-43

92.13

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLLESTPN +MLQQFSNPANT+VHFETTGPEIWEDT GQVDIFVMGIGSGGTVSGVGQYLKS+NPNV+IYGVEPAESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

Q43153 Bifunctional L-3-cyanoalanine synthase/cysteine synthase, mitochondrial

5.4e-42

91.01

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKA  LL+STP+GFMLQQF+NPANTQVHFETTGPEIWEDT+G+VDIFVMGIGSGGTVSGVG+YLKSQNPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

Q76MX2 Bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial

1.4e-42

88.76

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGT+KKAYDLLESTPN +MLQQFSNPANTQ HFETTGPEIWEDT+G VDIFVMGIGSGGTVSGVGQYLKS+NPNVKIYG+EP ESN+L
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

Q9S757 Bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial

4.6e-41

87.64

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLL+STP+ FM QQF+NPANTQ+HF+TTGPEIWEDT G VDIFVMGIGSGGTVSGVG+YLKS+NPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

Arabidopsis top hits

e value

%identity

Alignment

AT3G59760.1 O-acetylserine (thiol) lyase isoform C

3.4e-31

61.8

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        M G V+KA ++L++TP+ +MLQQF NPAN ++H+ETTGPEIW+DTKG+VDIFV GIG+GGT++GVG+++K +NP  ++ GVEP ES+IL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

AT3G59760.3 O-acetylserine (thiol) lyase isoform C

3.4e-31

61.8

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        M G V+KA ++L++TP+ +MLQQF NPAN ++H+ETTGPEIW+DTKG+VDIFV GIG+GGT++GVG+++K +NP  ++ GVEP ES+IL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

AT3G61440.1 cysteine synthase C1

3.3e-42

87.64

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLL+STP+ FM QQF+NPANTQ+HF+TTGPEIWEDT G VDIFVMGIGSGGTVSGVG+YLKS+NPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

AT3G61440.2 cysteine synthase C1

3.3e-42

87.64

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLL+STP+ FM QQF+NPANTQ+HF+TTGPEIWEDT G VDIFVMGIGSGGTVSGVG+YLKS+NPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

AT3G61440.3 cysteine synthase C1

3.3e-42

87.64

Show/hide

Query:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL
        MGGTVKKAYDLL+STP+ FM QQF+NPANTQ+HF+TTGPEIWEDT G VDIFVMGIGSGGTVSGVG+YLKS+NPNVKIYGVEPAESNIL
Subjt:  MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNIL

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGGAGGTACTGTCAAAAAGGCTTATGATCTTTTGGAATCCACACCTAATGGTTTCATGCTCCAACAATTCTCAAACCCTGCCAATACTCAGGTGCATTTTGAAACCAC
TGGGCCTGAGATTTGGGAGGATACAAAAGGACAAGTTGACATTTTTGTGATGGGAATAGGCAGTGGAGGGACTGTCTCTGGAGTGGGACAGTATTTGAAATCCCAAAATC
CCAATGTTAAGATTTATGGAGTGGAGCCTGCTGAAAGTAATATACTGTGCTTAGTTTTGCCAATACAAAGCTGTAGACAGACCCAAGTCCATAGAACTATAAAAACCCGA
ACAAGAATTCCTAAAAGGACGTTGGTTGTGCTCGCTCCGGAAGCTCAAAAAATGGGCAACCAAACTGTCTTCTTAAAGTTCTAA

mRNA sequence

Show/hide mRNA sequence

GACCCAACTAAAGGCATGGGAGGTACTGTCAAAAAGGCTTATGATCTTTTGGAATCCACACCTAATGGTTTCATGCTCCAACAATTCTCAAACCCTGCCAATACTCAGGT
GCATTTTGAAACCACTGGGCCTGAGATTTGGGAGGATACAAAAGGACAAGTTGACATTTTTGTGATGGGAATAGGCAGTGGAGGGACTGTCTCTGGAGTGGGACAGTATT
TGAAATCCCAAAATCCCAATGTTAAGATTTATGGAGTGGAGCCTGCTGAAAGTAATATACTGTGCTTAGTTTTGCCAATACAAAGCTGTAGACAGACCCAAGTCCATAGA
ACTATAAAAACCCGAACAAGAATTCCTAAAAGGACGTTGGTTGTGCTCGCTCCGGAAGCTCAAAAAATGGGCAACCAAACTGTCTTCTTAAAGTTCTAA

Protein sequence

Show/hide protein sequence

MGGTVKKAYDLLESTPNGFMLQQFSNPANTQVHFETTGPEIWEDTKGQVDIFVMGIGSGGTVSGVGQYLKSQNPNVKIYGVEPAESNILCLVLPIQSCRQTQVHRTIKTR
TRIPKRTLVVLAPEAQKMGNQTVFLKF

PI0002743 (gene) of Melon (PI 482460) v1 genome