CuGenDBv2

Gene ID	PI0004362
Organism	Cucumis metuliferus PI 482460 (Melon (PI 482460) v1)
Description	26S protease regulatory subunit 6A homolog
Genome location	chr02:18157401..18162409
RNA-Seq Expression	PI0004362
Synteny	PI0004362
Gene Ontology terms	GO:0031323 - regulation of cellular metabolic process (biological process) GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process (biological process) GO:0051171 - regulation of nitrogen compound metabolic process (biological process) GO:0060255 - regulation of macromolecule metabolic process (biological process) GO:0080090 - regulation of primary metabolic process (biological process) GO:0005634 - nucleus (cellular component) GO:0008540 - proteasome regulatory particle, base subcomplex (cellular component) GO:0000166 - nucleotide binding (molecular function) GO:0016787 - hydrolase activity (molecular function) GO:0036402 - proteasome-activating ATPase activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

WP_152952109.1 hypothetical protein, partial [Escherichia coli]

4.7e-06

52.17

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFLWEAEMIKIKAQELKTKEGHASKILGFKFQY
        MV+DTNLEEDQLASMTT DI++AS LLDNEIRIL+EE   +   +++++ + K KE      L  +  Y
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFLWEAEMIKIKAQELKTKEGHASKILGFKFQY

XP_004135596.1 26S proteasome regulatory subunit 6A homolog [Cucumis sativus]

4.2e-07

63.33

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK
        MV+DTNLEEDQLASMTT+DII+AS LLDNEIRIL+EE       W++   KIK  + K K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK

XP_015933548.1 26S protease regulatory subunit 6A homolog [Arachis duranensis]

2.3e-05

49.28

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFLWEAEMIKIKAQELKTKEGHASKILGFKFQY
        MV+DTNLE+DQLA+MTT DI++AS LLDNEIRIL+EE   +   +++++ + K KE      L  +  Y
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFLWEAEMIKIKAQELKTKEGHASKILGFKFQY

XP_022136131.1 26S proteasome regulatory subunit 6A homolog [Momordica charantia]

4.2e-07

63.33

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK
        M +DTNLEEDQLASMTT DII+AS LLDNEIRIL+EEF      W++   KIK  + K K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK

XP_038880104.1 26S proteasome regulatory subunit 6A homolog [Benincasa hispida]

7.2e-07

63.33

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK
        MV+DTNLEEDQLASMTT DII+AS LLDNEIRIL+EE       W++   KIK  + K K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LWD4 AAA domain-containing protein

2.1e-07

63.33

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK
        MV+DTNLEEDQLASMTT+DII+AS LLDNEIRIL+EE       W++   KIK  + K K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK

A0A1S3BQ90 26S protease regulatory subunit 6A homolog

2.1e-07

63.33

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK
        MV+DTNLEEDQLASMTT+DII+AS LLDNEIRIL+EE       W++   KIK  + K K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK

A0A5D3CEH3 26S protease regulatory subunit 6A-like protein

2.1e-07

63.33

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK
        MV+DTNLEEDQLASMTT+DII+AS LLDNEIRIL+EE       W++   KIK  + K K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK

A0A6J1C2N5 26S proteasome regulatory subunit 6A homolog

2.1e-07

63.33

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK
        M +DTNLEEDQLASMTT DII+AS LLDNEIRIL+EEF      W++   KIK  + K K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL-----WEAEMIKIKAQELKTK

A0A6P4B402 26S protease regulatory subunit 6A homolog

1.1e-05

49.28

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFLWEAEMIKIKAQELKTKEGHASKILGFKFQY
        MV+DTNLE+DQLA+MTT DI++AS LLDNEIRIL+EE   +   +++++ + K KE      L  +  Y
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFLWEAEMIKIKAQELKTKEGHASKILGFKFQY

SwissProt top hits

e value

%identity

Alignment

O04019 26S proteasome regulatory subunit 6A homolog B

1.2e-04

53.45

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL---WEAEMIKIKAQELKTK
        M +DT+ E DQLASMTT DI +AS LL NEIRIL+EE      + E +K K +E + K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL---WEAEMIKIKAQELKTK

O23894 26S proteasome regulatory subunit 6A homolog

7.0e-05

65.79

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Query:  MVKDT-NLEEDQLASMTTKDIIQASHLLDNEIRILREE
        MV+DT + EEDQLASM+T+DI++A+ LL+NEIRIL+E+
Subjt:  MVKDT-NLEEDQLASMTTKDIIQASHLLDNEIRILREE

P54776 26S proteasome regulatory subunit 6A homolog

1.9e-05

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL---WEAEMIKIKAQELKTK
        M +D+N E+DQL +M+T+DII+AS LLDNEIRI++EE      E +  K K +E + K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL---WEAEMIKIKAQELKTK

Q9SEI2 26S proteasome regulatory subunit 6A homolog A

7.0e-05

68.42

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Query:  MVKDT-NLEEDQLASMTTKDIIQASHLLDNEIRILREE
        MV+DT + EEDQLASM+T+DI +A+ LLDNEIRIL+E+
Subjt:  MVKDT-NLEEDQLASMTTKDIIQASHLLDNEIRILREE

Arabidopsis top hits

e value

%identity

Alignment

AT1G09100.1 26S proteasome AAA-ATPase subunit RPT5B

8.5e-06

53.45

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Query:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL---WEAEMIKIKAQELKTK
        M +DT+ E DQLASMTT DI +AS LL NEIRIL+EE      + E +K K +E + K
Subjt:  MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFL---WEAEMIKIKAQELKTK

AT1G24706.1 THO2

6.1e-04

67.86

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Query:  EGHASKILGFKFQYYQRIEVNASCGVVL
        + HAS+ILGFKFQYYQR+EVN+   V L
Subjt:  EGHASKILGFKFQYYQRIEVNASCGVVL

AT1G24706.1 THO2

5.2e-03

80.95

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Query:  EEFLWEAEMIKIKAQELKTKE
        EEFLWEA+M+KIKAQ+LK KE
Subjt:  EEFLWEAEMIKIKAQELKTKE

AT1G24706.2 THO2

6.1e-04

67.86

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Query:  EGHASKILGFKFQYYQRIEVNASCGVVL
        + HAS+ILGFKFQYYQR+EVN+   V L
Subjt:  EGHASKILGFKFQYYQRIEVNASCGVVL

AT1G24706.2 THO2

5.2e-03

80.95

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Query:  EEFLWEAEMIKIKAQELKTKE
        EEFLWEA+M+KIKAQ+LK KE
Subjt:  EEFLWEAEMIKIKAQELKTKE

AT3G05530.1 regulatory particle triple-A ATPase 5A

5.0e-06

68.42

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Query:  MVKDT-NLEEDQLASMTTKDIIQASHLLDNEIRILREE
        MV+DT + EEDQLASM+T+DI +A+ LLDNEIRIL+E+
Subjt:  MVKDT-NLEEDQLASMTTKDIIQASHLLDNEIRILREE

Sequences

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CDS sequence

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ATGGTCAAAGATACGAACCTCGAAGAAGACCAGTTGGCTTCTATGACCACAAAAGACATCATTCAGGCTTCTCATCTTCTTGACAATGAGATTCGAATCCTCAGGGAGGA
ATTTCTATGGGAGGCTGAAATGATAAAAATTAAGGCGCAAGAATTGAAGACTAAAGAGGGTCATGCTTCAAAAATCCTTGGGTTCAAATTTCAGTATTATCAGCGCATTG
AAGTAAATGCGAGTTGTGGAGTTGTATTGTCTGGGTCGCCTACCACACAAAGGTATGTTTCAATGCAACTTACTCCTGCAATTCTAACTCATGCTAGCCCTCTAATGCAT
AAACTCTTAATTTCCCGAAATCATGCTTTGATACCAAATTTGTCACACTCCGTTCTAGATTATCCTTCTAACCTAGATCGAGGCATGAAATGTAAGCAATATGATCAAAA
GAATTCTAAGGGGCGTTCTGATGTTCCTTTGGAACATTTGGGCTGCTCAAGTCGCGTTCTGTCTCGGGCATGTTGCGAGGAGGGTATTCTGGGGTGGGGCGTGACATGA

mRNA sequence

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Protein sequence

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MVKDTNLEEDQLASMTTKDIIQASHLLDNEIRILREEFLWEAEMIKIKAQELKTKEGHASKILGFKFQYYQRIEVNASCGVVLSGSPTTQRYVSMQLTPAILTHASPLMH
KLLISRNHALIPNLSHSVLDYPSNLDRGMKCKQYDQKNSKGRSDVPLEHLGCSSRVLSRACCEEGILGWGVT

PI0004362 (gene) of Melon (PI 482460) v1 genome